International Archives of

Medical MicrobiologyISSN: 2643-4008

Early Online

 Open Access DOI:10.23937/2643-4008/1710014

Liposomal Amphotericin-B in Saline Shows Promising Efficacy against Candida auris compared to Azoles, Echinocandins and Other Amphotericin-B Formulations in Dextrose and Deoxycholate Suspension

Vijay Pancholi

Article Type: Brief Note | First Published: October 25, 2021

Fungal infection caused by Candida auris is now a global crisis. However, its multidrug-resistant nature and onerous identification have left limited therapeutic options resulting in 30-60% mortality. Amphotericin-B (AmB), a broad-spectrum and a potent fungicidal with a rare resistance pattern, is considered a gold-standard antifungal drug. Yet, its antifungal potential is not fully recognized under the pretext of its potential nephrotoxicity. Liposomal AmB formulations are safer than AmB-Deoxyc...

 Open Access DOI:10.23937/2643-4008/1710012

Comparative Transcriptomic Analysis of Pseudomonas aeruginosa Isolates from ICU Patients with Acute and Chronic Pneumonia

Jayasimha Rao, PhD, Adenike Adenikinju, MD, James M. Gray, MS, Lily Colpitts, MD, Alyson Prorock, BS, Yongde Bao, PhD, Thomas M. Kerkering, MD, Dorothy C. Garner, MD and Roderick V. Jensen, PhD

Article Type: Original Article | First Published: June 17, 2021

Multidrug-resistant (MDR) and virulent pathogenic strains of Pseudomonas aeruginosa (Pa) are among the most dangerous pathogens in healthcare-associated infections. In this study, a comparative analysis was performed on two clinical Pa strains from pneumonia patients, 1) An acute strain (CMC-115) and 2) A chronic multidrug- and carbapenemresistant strain (CMC-097) with distinct phenotypic and genetic characteristics. A transcriptome analysis using both the Pseudomonas DNA GeneChip microarray and...

 Open Access DOI:10.23937/2643-4008/1710011

The Importance of Microorganisms and Their Effects on Medicinal Plants and Their Various Applications

Abdlmanam Fakron, Idress Hamad Attitalla, Mohamed Younes A Hassan and Sumeet Dwivedi

Article Type: Review Article | First Published: April 30, 2021

Since photosynthesis is the primary process through which light energy absorbed and converted into organic matter, thus, plant chlorophyll pigment (forms A and B) plays an essential role in the progression absorbed solar energy and synthesis of organic matter in a plant. Therefore, this paper aims at the extent to which the optical activity of chlorophyll molecules monitored and methods (non-destructive and destructive) for quantification of chlorophyll content in plants. These methods using to ...

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