The association between genetic variants and respiratory conditions such as allergy and chronic rhinosinusitis has been the subject of extensive research. While the mitochondrial tRNA A3243G mutation has been extensively studied in the context of mitochondrial disorders, its potential role in inflammatory conditions such as allergy and chronic rhinosinusitis is not as well understood. In this study, we aim to explore and understand the potential link between the mitochondrial tRNA A3243G mutatio...

Type 2 diabetes (T2DM) is a multifactorial disease with serious complications, particularly degenerative. Currently, several genes have been identified in its pathogenesis, including the 5,10-methylene tetrahydrofolate reductase (MTHFR) gene with an association of the c.677C>T and c.1298A>C variants. The aim of this study was first to investigate the frequency of these variants in Congolese subjects with T2DM and to compare them with healthy controls. Secondly, to establish a correlation between...