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Open Access DOI:10.23937/2378-3419/1410186
Yoriko Nomura, Tomoki Ryu, Kazuki Takeishi, Gen Yamamoto, Yoshiyuki Wada and Yuko Takami
Article Type: Original Article | First Published: 2024/02/08
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive and challenging cancers, causing substantial mortality worldwide. Despite advancements in treatment modalities, the prognosis for patients with PDAC remains dismal, emphasizing the critical need for identifying factors influencing early recurrence and survival post-surgery. This study aimed to clarify the risk factors for early recurrence (within 1 year) in patients who underwent upfront surgery for resectable PDAC....
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Open Access DOI:10.23937/2378-3419/1410185
Genomic Profiling of Breast Cancer: A Single Institution's Experience and Impact on Patient Outcomes
Ezzelkdin M. Ibrahim, Bushra A. Al-Quzi, Duaa A. Jabal, Ali M. Bayer, Ahmed Y. Shaheen, Zeinab A. Morsi, Majidah M. Ahmed, Mohammed H. Kulak and Ahmed A. Refae
Article Type: Research Article | First Published: 2024/02/02
Genomic profiling (GP) of breast cancer (BC) tumors is a promising approach to identifying genetic mutations that aid patient management. Herewith, we present a single institutional experience of performing GP to assess its impact on patient outcomes. Tumor tissues of 56 patients were tested using the FoundationOne® next-generation sequencing platform. Patients median age was 54 years; 51 patients had metastatic BC, while 5 had an early-stage disease. The most frequently identified genes were T...
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Volume 11
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Issue 1