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International Archives of

Endocrinology Clinical ResearchISSN: 2572-407X

Early Online

 Open Access DOI:10.23937/2572-407X.1510039

Challenges in Managing Primary Hyperparathyroidism during Pregnancy: Case Series

Dineash Kumar Kannesan, QingCi Goh, ChinVoon Tong and PohShean Wong

Article Type: Case Series | First Published: March 01, 2025

Primary hyperparathyroidism (PHPT) in pregnancy is uncommon and poses challenges in managing it with desired good maternal and fetal outcomes. We report two cases of PHPT in pregnancy with challenges in localizing the lesion, one localized successfully using low dose 99mTc-sestamibi and the other patient required neck exploration....

 Open Access DOI:10.23937/2572-407X.1510038

Iatrogenic Hypoparathyroidism: Basal Ganglia Calcification, Bilateral Cataract, and Medullary Nephrocalcinosis

Md Ejaz Alam, Shoiab Mohammad Patto, Mohammad Hayat Bhat and Mohammad Afaan Bhat

Article Type: Case Report | First Published: 2024/07/25

Hypoparathyroidism is a rare endocrine disorder characterised by low levels of serum calcium and parathyroid hormone. This report highlights iatrogenic hypoparathyroidism in a juvenile Graves' disease patient post near-total thyroidectomy, leading to low serum calcium and parathyroid hormone levels. Uncommon complications emerged, including asymptomatic basal ganglia calcification, medullary nephrocalcinosis, and bilateral cataracts. The case emphasises the need to recognize and manage the compl...

 Open Access DOI:10.23937/2572-407X.1510037

DKA at Diagnosis of Type 1 Diabetes Mellitus and Risk Factors in Children Aged 6 Months to 19 Years at David Bernardino National Pediatric Hospital-Angola

Ketha Francisco, Adelino Alex and Rosalon Pedro

Article Type: Cross Sectional Study | First Published: 2024/07/22

Diabetes mellitus is a disorder of metabolic homeostasis controlled by the beta cell hormone; insulin, leading to abnormal metabolism of carbohydrates, proteins and fats. Type 1 is caused by an absolute deficiency of insulin due to the progressive destruction of the beta cells of the pancreas. While the prevalence is between 15-30 million patients worldwide, the incidence of T1DM varies sharply across countries and age groups; with the highest incidence observed in children between 10 and 14-yea...

 Open Access DOI:10.23937/2572-407X.1510036

Cardiovascular Safety Outcomes of Testosterone Replacement in Men with Late-Onset and Functional Hypogonadism: A Systematic Review

Oluwarotimi B. Olopade, Ifedayo A. Odeniyi, Sekinat A. Adejumobi, Ifeyinwa N. Ijeh, Olufemi A Fasanmadeo and Atul Kalhan

Article Type: Systematic Review | First Published: 2024/01/19

A systematic review was conducted using the preferred reporting items for systematic reviews and meta-analyses (PRISMA) 2020 guidelines. Six databases (PubMed, Scopus, Wiley Library, Embase, Cochrane database for systematic reviews and Google Scholar) were searched for relevant articles. The Distiller-SR software was used for journal screening, duplicate removal and data extraction....

 Open Access DOI:10.23937/2572-407X.1510035

Refractory Hyperglycemia and Hypokalemic Paralysis: Rare Initial Presentation of Cushing Disease

Richmond R Gomes and Habiba Akhter

Article Type: Case Report | First Published: 2023/12/30

Cushing syndrome (CS) is a rare disease that results from prolonged supraphysiologic tissue action of glucocorticoids. This can be caused by a tumor of the adrenal glands, the lungs or the pituitary gland. When a pituitary tumor produces too much ACTH (adrenocorticotropic hormone), it causes the overproduction of cortisol by the adrenal glands. When the pituitary is the source of the over production, it is called Cushing's disease. Cushing's disease (CD) remains a diagnostic and therapeutic chal...

 Open Access DOI:10.23937/2572-407X.1510034

Treatment Outcome and Associated Factors among Type 1 Diabetic Children Admitted with DKA in Bahir Dar City Public Referral Hospital, Northwest, Ethiopia: A Cross-Sectional Study

Fentahun Meseret, Silenat Muluken, Tilaye Gebru and Tsegasew Embiale

Article Type: Clinical Endocrinology | First Published: 2023/12/30

Length of hospital stay, complication and mortality are the primary outcomes that should be measured during diabetic ketoacidosis management. However, data associated with the length of stay, complications, and mortality rate due to diabetic ketoacidosis remains limited in Ethiopia. In addition, nonfiction is very scarce about factors associated with treatment outcomes starting from its initial presentation and the overall management process. ...

 Open Access DOI:10.23937/2572-407X.1510033

Navigating Diagnostic Challenges in Endocrinology: A Case Report of Macro-TSH

Stephanie T Walls, BSc and Mary Ryan, MB BCH BAO MA TCD MD MRCP

Article Type: Case Report | First Published: March 27, 2023

A 47-year-old female was referred with elevated plasma thyroid stimulating hormone (TSH) levels. The patient reported increased hair loss and infrequent menstrual periods which is likely related to her recent significant weight loss and perimenopausal symptoms respectively. No other stigmata of thyroid disease were noted, and the patient appeared euthyroid clinically. ...

 Open Access DOI:10.23937/2572-407X.1510032

Accuracy of Flash Glucose Monitoring in Critically Ill Patients Receiving Intravenous Insulin

Jia Wei Tan, MD, Sachin K Majumdar, MD

Article Type: Brief Report | First Published: December 11, 2022

To compare the Free Style Libre (FSL) 2 14- day Flash Glucose Monitoring (FGM) and Point-Of-Care Capillary (POC) Blood Glucose (BG) testing among critically ill patients who receive insulin infusion. We conducted an open-label, prospective study and enrolled stepdown or critical care unit patients on intravenous insulin. Paired POC and GCM values were obtained to calculate the Mean Absolute Relative Difference (MARD). Accuracy was further evaluated with error grid analysis between matched glucos...

 Open Access DOI:10.23937/2572-407X.1510031

Use of Insulin during the Current Pandemic

Selia Chowdhury, Mehedi Hasan Bappy, Md. Shahraj Chowdhury, Santiago Clocchiatti-Tuozzo, Muhammad Haseeb ul Rasool, Shreeya Desai, Catalina Sekzer and Pawan Kumar Thada

Article Type: Literature Review | First Published: May 31, 2022

Insulin is one of the greatest medical discoveries of the twentieth century and it continues to be the solitary effective treatment for type 1 diabetes mellitus patients and save millions of lives around the world. In 2021, we have rejoiced 100 years of insulin discovery....

 Open Access DOI:10.23937/2572-407X.1510030

Clinical, Endocrinological and Histopathological Evaluation of Patients with Adrenal Incidentaloma - A Single-Center and Retrospective Study Including 320 Patients

Ahmet GORGEL, Devrim DOLEK CETİNKAYA, Fusun SALGUR, Mustafa DEMIRPENCE, Husnu YILMAZ and Mitat BAHCECİ

Article Type: Research Article | First Published: April 14, 2022

The aim of our study is to evaluate the patients with adrenal incidentaloma in terms of clinical and endocrinological features and, to determine whether a correlation between the malignancy and preoperative tumor size via analyzing of the histopathological results of the masses. This study was performed on 320 patients (86 males, 234 females) with adrenal incidentaloma who visited our clinic during a period of 3 years. Chi-square test was used to categorize the patients according to their hormon...

 Open Access DOI:10.23937/2572-407X.1510029

An Interesting Case of DeQuervain’s Thyroiditis

Arul Prakash Rajadurai

Article Type: Case Report | First Published: February 26, 2022

We present an interesting case of De Quervin’s Thyroiditis following Enteric fever with classical features of pain neck and hyperthyroidism ended up in Hypothyroidism. A 34-years-old women consulted surgeon for neck pain and swelling for 1 week, and expressed her fear of cancer of thyroid. She told that her distant relative had thyroid cancer. Surgeon noted a tender goitre, moving with deglutition, no nodules or nodes in the neck and mild features of hyperthyroidism like palpitation, tremor. H...

Volume 8
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