International Archives of Endocrinology Clinical Research is an open access peer reviewed journal that publishes articles in the field of endocrinology metabolism and clinical research. The journal mainly encompass the endocrine glands, its secretions and their coordination with metabolism.

International Archives of Endocrinology Clinical Research is a reliable source of information for the researcher and practitioners in the field of endocrinology such as Adrenal Disorders, Anti-obesity Drugs, Atypical Antipsych, Autoantibodies, Autoimmune Attack, Beta Cell Loss, Calcium Homeostasis Disorders, Comparative Endocrinology, Diabetes Insipidus, Diabetes Mellitus, Endocrine Emergencies, Endocrine Tumors, Endogenous Insulin, Gastric Balloon, Gestational Diabetes, Glucose Homeostasis, Histogenesis, Hormones, Hyperglycemia, Hypoglycemia, Ketoacidosis, Ketosis, Metabolism, Neonatal Diabetes, Neuroendocrinology, Obesity Risks, Organogenesis, Pediatric Endocrinology, Pituitary Gland Disorders, Reproductive Endocrinology, Sex hormone Disorders, Thyroid Disorders, etc. Two independent review comments followed by editor's decision will be considered to publish the article. IAECR is a permanent archive of endocrinology information under open access category provides its global readers with free access to its content, thus serving the scientific community.

 
Journal Information

Title: International Archives of Endocrinology Clinical Research

ISSN: 2572-407x

Editor-in-chief: Garth Graham

NLM title abbreviation: Int Arch Endocrinol Clin Res

ISO abbreviation: Int Arch Endocrinol Clin Res

Other titles: IAECR

Category: Endocrinology

DOI: 10.23937/2572-407X

Peer review: Double blind

Review speed: 3 weeks

Fast-track review: 10 days

Publication format (s): Electronic and print

Publication policy: Open Access; COPE guide

Publication type(s): Periodicals

Publisher: ClinMed International Library

Country of publication: USA

Language: English

Contact email: contact@clinmedjournals.org

 
Articles Search by   Keyword   |   Journal title   |   Author name   |   DOI

 

 Open Access DOI:10.23937/2572-407X.1510027

A Large Papillary Carcinoma of Thyroid Gland

Alhad Mulkalwar, Sujay Jaju and Samir Deolekar

Article Type: Clinical Image | First Published: September 30, 2021

A 55-year-old female patient presented with a swelling in the front and sides of the neck (Figure 1) for last 1 year which was initially increasing slowly in size but for the last 5 months, the patient noticed that the swelling was rapidly increasing in size. She was complaining of dull aching pain over the swelling for last 3 months. She also complained of slight hoarseness of voice for last 2 months. She had slight difficulty in swallowing and breathing. There were no symptoms suggestive of hy...
 

 Open Access DOI:10.23937/2572-407X.1510026

Graves Thyrotoxicosis and Cerebral Venous Sinus Thrombosis Causality or Chance Alone?

Richmond Ronald Gomes

Article Type: Case Report | First Published: September 22, 2021

Cerebral Venous Sinus Thrombosis (CVST) is a rare cerebrovascular condition accounting for 0.5-1% of all types of strokes in the general population and 12.5% of cases are considered to be idiopathic. Hypercoagulability, local bloodstream stasis, and vessel wall abnormalities may contribute to the development of this condition. The thyrotoxic phase of Graves’ disease is associated with venous thrombosis caused by hypercoagulability, which is in turn induced by increased levels of homocysteine a...
 

 Open Access DOI:10.23937/2572-407X.1510025

U.S. Survey Investigating Gaps between Patients and Specialists in the Treatment of Severe Hypoglycemia and Impressions of the Ease-of-Use of Liquid-Stable Glucagon for Subcutaneous Injection

James M. Meyer and Mary C. Devona

Article Type: Research Article | First Published: August 20, 2021

Severe hypoglycemia is an emergency condition where very low blood sugar may lead to confusion, seizure, unconsciousness, and if left untreated, death. It has been identified as a cause for recurrent morbidity in people with either Type 1 Diabetes (T1D) or Type 2 Diabetes (T2D); however, the understanding of signs and symptoms of Severe Hypoglycemia (SH), as well as when to use glucagon, tend to vary between patients, caregivers, and adult and pediatric endocrinologists (specialists). The purpos...
 

 Open Access DOI:10.23937/2572-407X.1510024

The Incidence and Predictors of Poor Glycemic Control among Adults with Type 2 Diabetes Mellitus in Ambulatory Clinic of Mettu Karl Referral Hospital, South Western, Ethiopia: A Prospective Cross Sectional Study

Gudisa Bereda and Gemechis Bereda

Article Type: Research Article | First Published: August 11, 2021

Diabetes mellitus refers to a grouping of metabolic diseases involving prolonged hyperglycemia caused by the inadequate secretion of insulin, poor insulin action, or a combination of the two. Poor glycaemic control is a major public health problem among patients with type 2 diabetes mellitus. To expose the incidence and predictors of poor glycemic control among adults with type 2 diabetes mellitus in ambulatory clinic of Mettu Karl Referral Hospital. An institutional based prospective cross-sect...
 

 Open Access DOI:10.23937/2572-407X.1510023

Is Oxidative Stress a Consequence of Hyperglycemia? Or is Hyperglycemia the Consequence of Oxidative Stress? Or are Both Caused by Insulin Resistance?

İhsan Boyacı, Türkan Yiğitbaşı and Handan Ankaralı

Article Type: Original Article | First Published: July 19, 2021

The oxidative status may not only be a cause of diabetes, but also a consequence of diabetes. We aimed to evaluate the relationship between hyperglycemia levels and oxidative status in patients with type 2 diabetes using Total Antioxidant Capacity (TAC), Total Oxidative State (TOS) and Oxidative Stress İndex (OSI). In this study, 145 patients diagnosed with prediabetes (n = 28) and type 2 diabetes (n = 117) according to HbA1c and oral glucose tolerance test (OGTT) levels were divided into five ...
 

 Open Access DOI:10.23937/2572-407X.1510022

The Impact of Glucose Load and Worse Metabolic Status Post Initiation of Peritoneal Dialysis

Nadiya Al Rahbi, Issa Al Salmi, Sadiq Abdul Baqi, Muna Al Bulushi and Suad Hannawi

Article Type: Research Article | First Published: December 03, 2020

End-Stage Kidney Disease (ESKD) has a major effect on global health, both as a direct cause of global morbidity and mortality. Peritoneal Dialysis (PD) utilization increases gradually due to increase of patient’s awareness for different types of RRT. Glucose constitutes the main component of the PD fluid utilized by the patients. In this study, we aim to evaluate the various demography and clinical and laboratory data before and a year after initiation of PD and determine the impact of glucose...
 

 Open Access DOI:10.23937/2572-407X.1510020

Surgical Resection Offers Long-Term Remission in a Solitary Lung Metastasis of Differentiated Thyroid Carcinoma - A Case Report and Literature Review

Idit Tessler MD, MPH, Oded Cohen MD, Judith Diment MD, Yonatan Lahav MD, Doron Halperin MD, MPH and Taiba Zornitzki MD

Article Type: Case Report | First Published: May 18, 2020

Solitary pulmonary lung nodule is a rare presentation of differentiated thyroid metastatic disease with significantly increased mortality. Current data about diagnosis and treatment are limited, based mostly on case reports. The patient initially underwent a total thyroidectomy and received radioactive treatment for locally advanced papillary thyroid carcinoma. During the follow-up scans, a solitary nodule in the left lung was identified, with positive uptake in fluorodeoxyglucose PET-CT but not...
 

 Open Access DOI:10.23937/2572-407X.1510021

A Case of Severe Hyponatremia Secondary to Pituitary Macroadenoma with Covid-19 Infection, Endocrinological Responses

José Carlos de la Flor Merino, MD, Laura Mola Reyes, MD, Francisco Valga Amado, MD, Alexander Marshall and Miguel Rodeles del Pozo, MD

Article Type: Letter to the Editor | First Published: August 03, 2020

SARS-CoV-2 disease (COVID-19) has dramatically increased since March 2020. There is insufficient data to establish the risk of acquiring the hyponatremia in patient with COVID-19 infection. We report here the clinical features and therapeutic course of the severe hyponatremia secondary to pituitary macroadenoma with confirmed COVID-19 pneumonia. This is a 59-year-old man without renal disease, who developed severe hyponatremia, hardly explained by the emetic episode and/or diuretic treatment wit...
 

 Open Access DOI:10.23937/2572-407X.1510019

No Significant Difference in Outcomes for Surgical Treatment of Thyroid Cancer in Kidney Transplant Recipients - Analysis of the HCUP NIS Data

Darren B Abbas, MD, Eric Goldschmidt, MD, Christina Camick, MD, Weikai Qu, MD, PhD and Jorge Ortiz, MD

Article Type: ORIGINAL ARTICLE | First Published: December 13, 2019

Solid organ transplant recipients, and in particular Kidney Transplant (KTx) patients, are at increased risk for developing thyroid cancers due to immunosuppression and improved long-term survival post-transplant. Using the HCUP NIS database, we compared mortality rate, disposition, LOS, and total hospital charge between KTx and Non-KTx patients following thyroidectomy for thyroid cancer during 2008-2014....
 

 Open Access DOI:10.23937/2572-407X.1510018

A Current Approach to Hyperprolactinemia

Lau CS and Aw TC

Article Type: REVIEW ARTICLE | First Published: December 04, 2019

Prolactin is a hormone secreted by the anterior pituitary lactotrophs and is controlled by the influence of hypothalamic dopamine. PRL stimulates the proliferation and differentiation of mammary cells for lactation. There are many causes for hyperprolactinemia, including analytical, physiological, pharmacological, pathological and idiopathic causes. Macroprolactin is a significant analytical cause of hyperprolactinemia, and the most common cause of pathological hyperprolactinemia is prolactin se...
 

 Open Access DOI:10.23937/2572-407X.1510017

Contribution of 99M TC-HMDP Bone Scintigraphy in the Diagnosis of Fibrous Dysplasia of Mccune Albright Syndrome in Infant: A Case Report

F Fokoue, S El Mselmi and N Ismaili Alaoui

Article Type: REVIEW ARTICLE | First Published: November 16, 2019

We report the case of an infant with McCune-Albright syndrome who was diagnosed with polyostotic fibrous dysplasia using 99m Tc-HMDP bone scintigraphy outside the clinical presentation, although not conventionally presented by the infant. The aim of this work is to show the interest of bone scintigraphy in the diagnosis of McCune Albright syndrome....
 

 Open Access DOI:10.23937/2572-407X.1510016

Close Relationship of Alzheimer's Disease (AD) and Glucose Dysregulation

Hiroshi BANDO, MD, PhD

Article Type: COMMENTARY | First Published: June 03, 2019

One of the recent crucial medical problems in the world has been diabetes mellitus, which is increasing in developed and also developing countries. Furthermore, dementia and Mild Cognitive Impairment (MCI) in the elderly has been also medical and social problems due to the extended life span....
 

 Open Access DOI:10.23937/2572-407X.1510015

Reference Intervals for TSH on the Architect Analyser Based on the National Academy of Clinical Biochemistry (NACB) Guidelines Derived from Healthy Multi-Ethnic Asians Attending a Community Health Fair

TC Aw, J Sickan, Shaoqing X Du, J Li, H Janel and A Beshiri

Article Type: Research Article | First Published: May 30, 2019

Thyroid diseases are prevalent in Malaysia. A community health survey was undertaken to improve community awareness of the risks of common non-communicable diseases such as thyroid disorders and the benefits of screening for prevention and early detection of these conditions. Thyroid stimulating hormone (TSH) is the main biomarker and initial test for thyroid dysfunction. However, no formal reference interval (RI) data for TSH is available in Malaysia and South East Asia. All TSH reference inter...
 

 Open Access DOI:10.23937/2572-407X.1510014

Influence of Insulin Resistance and TSH on the Risk of Malignancy of Thyroid Nodule

Erdal Sayyigit, Zafer Pekkolay and Alpaslan Kemal Tuzcu

Article Type: Original Article | First Published: October 12, 2018

The incidence of thyroid cancer has increased in recent years. This increase may be due to the change of metabolic parameters in patients. This study was designed to clarify the association of malignancy of thyroid nodules with metabolic parameters. This study designed as a cross-sectional study between January 2018 and May 2018. Samples were collected from the patients by thyroid fine needle biopsy and patients who had thyroid surgery. Group 1 patients were pathologically benign patients; Group...
 

 Open Access DOI:10.23937/2572-407X.1510013

Polycystic Ovary Syndrome: Genetic Contributions from the Hypothalamic-Pituitary-Gonadal Axis

Branavan Umayal, NV Chandrasekharan, WSS Wijesundera and Chandrika N Wijeyaratne

Article Type: Short Communication | First Published: October 08, 2018

Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder, present in 5-13% women of reproductive age. The endocrine manifestations of PCOS include excess androgen production of ovarian and/or adrenal origin and arrested follicular development leading to chronic oligo- or anovulation. Long term health risks of women with PCOS include cardiovascular disease, type 2 diabetes mellitus and endometrial cancer. PCOS is diagnosed by chronic anovulation, polycystic ovaries on ultrasound and bioche...
 

 Open Access DOI:10.23937/2572-407X.1510012

Serum Apelin-36 Levels in Migraine Patients with Aura and without Aura

Serap Yildirim, Arzu Sahin, Abdulkadir Yildirim, Mutlu Kuyucu, Engin Sebin, Senol Dane and Eda Dokumacioglu

Article Type: Research Article | First Published: July 28, 2018

Migraine is a chronic disease which affects approximately 12-18% of the society, can be accompanied by neurologic and systemic symptoms, and is characterised by mild or severe recurring headache attacks. The aim of this study is to determine serum apelin-36 level in the patients with migraine with aura and without aura and to compare the obtained data with the data of the healthy control group. The migren study group consisted of 44 women patients, suffering from migraine with (n = 16) and witho...
 

 Open Access DOI:10.23937/2572-407X.1510011

Serum Level of Cytokeratin-18/M30 Antigen is Increased in the Cases with Impaired Glucose Tolerance

Solen Himmetoglu, Selin Yuksel, Taner Damcı, Hasan Ilkova and Yildiz Dincer

Article Type: Research Article | First Published: November 22, 2017

Beta cell death by apoptosis is an important mechanism in beta cell dysfunction and development of diabetes. Inhibition of apoptosis may be helpful approach in the prevention of diabetes....
 

 Open Access DOI:10.23937/2572-407X.1510010

Pathobiology of Human Uterine Leiomyosarcoma for Development of Novel Diagnosis and Clinical Therapy

Takuma Hayashi, Tomoyuki Ichimura, Mari Kasai, Gal Gur, Pnina Yaish, Dorit Zharhary, Yae Kanai, Susumu Tonegawa, Nobuo Yaegashi and Ikuo Konishi

Article Type: Short Communication | First Published: September 28, 2017

Uterine sarcomas comprise a group of rare tumours with differing tumour pathobiology, natural history and response to clinical treatment. Diagnosis is often made following surgical treatment for presumed malignant mesenchymal tumours and benign tumours. Currently pre-operative diagnosis does not reliably distinguish between malignant mesenchymal tumours....
 

 Open Access DOI:10.23937/2572-407X.1510009

Associations between Thyroid Hormones and Blood and Urine Lead

Ram B Jain

Article Type: Research Article | First Published: July 01, 2017

Data from National Health and Nutrition Examination Survey for 2007-2012 were used to evaluate associations between urine and blood lead and Thyroid Stimulating Hormone (TSH), Free and Total Triiodothyronine (FT3, TT3), and Free and Total Thyroxine (FT4, TT4)....
 

 Open Access DOI:10.23937/2572-407X.1510008

Adrenal Neuroblastoma Mimicking Pheochromocytoma in an Adult with Neurofibromatosis Type 1

Harbi Khalayleh, Hilla Knobler, Vitaly Medvedovsky, Edit Feldberg, Judith Diment, Lena Pinkas, Guennadi Kouniavsky and Taiba Zornitzki

Article Type: Case Report | First Published: February 21, 2017

A 42-year-old normotensive woman with neurofibromatosis type 1 (NF1) with typical cutaneous manifestations (multiple neurofibromas, cafe-au-lait spots and axillary freckling), underwent evaluation for abdominal pain and a large left adrenal mass displacing the spleen pancreas and colon, was found upon a CT scan....
 

 Open Access DOI:10.23937/2572-407X.1510007

Myopathy Revealing Parathyroid Carcinoma

KS Moalla, N Bouzidi, M Damak, M Abid and C Mhiri

Article Type: Case Report | First Published: February 21, 2017

Primary hyperparathyroidism (PHPT) is defined as an inappropriate and excessive secretion of parathyroid hormone (PTH). It is usually asymptomatic and often diagnosed after a fortuitous discovery of hypercalcemia. We report the case of severe myopathy revealing PHPT secondary to parathyroid carcinoma (PC) with lung metastasis....
 

 Open Access DOI:10.23937/2572-407X.1510006

Update on Pituitary Folliculo-Stellate Cells

Maria Pires and Francisco Tortosa

Article Type: Mini Review | First Published: October 27, 2016

Folliculo-stellate cells (FSCs) are a non-endocrine population of sustentacular-like, star-shaped and follicle-forming cells, which contribute about 5-10% of elements from the anterior pituitary lobe. First identified with electron microscopy as non-hormone secreting accessory cells, light microscopy has revealed many of their cytophysiological features, and is known as positive for S-100 protein, a marker for FSCs. They are currently considered as functionally and phenotypically heterogeneous.....
 

 Open Access DOI:10.23937/2572-407X.1510005

Effect of Race/Ethnicity and Smoking on Diurnal Variations in Testosterone Levels

Ram B Jain

Article Type: Research article | First Published: December 10, 2015

The effect of race/ethnicity and smoking on diurnal variations in total serum testosterone level (T-TST) was evaluated by analyzing data from NHANES for 2011-2012 for adolescent and adult males. For adolescent males, diurnal variability in T-TST levels was substantially smaller among smokers than nonsmokers for non-Hispanic white (NHW) and Hispanics but the reverse was true for non-Hispanic black (NHB). For adult males, morning levels of T-TST were 21-31% higher than the T-TST levels during even...
 

 Open Access DOI:10.23937/2572-407X.1510004

Thyroid Profile of the Reference United States Population: Data from NHANES 2007-2012

Ram B Jain

Article Type: Research article | First Published: November 16, 2015

Objective: This study was undertaken to describe the thyroid profile of reference U.S. population including generating reference ranges for thyroid stimulating hormone (TSH), free and total triiodothyronine (FT3, TT3), free and total thyroxine (FT4, TT4), and thyroglobulin. Design and methods: Publically available data from National Health and Nutrition Examination Survey (NHANES) for the cycles 2007-2012 were analyzed for this purpose....
 

 Open Access DOI:10.23937/2572-407X.1510003

Hypercalcemia, an Uncommon Presentation of Hyperthyroidism

Fathimabeebi PK, Noor Bader Al Busaidi and Mohamed Al Lamki

Article Type: Case Report | First Published: October 13, 2015

Background: Moderate to severe hypercalcemia associated with hyperthyroidism is not very common and can raise a diagnostic challenge to the treating physician. Objective: To present a case of thyrotoxicosis manifested with symptoms of hypercalcemia and resolution of symptoms after rendering euthyroid. Method: We report the case of a 61 year old Omani gentleman, who presented with symptoms of hypercalcemia like weight loss (10 kg) with poor appetite, constipation and depression as first manifesta...
 

 Open Access DOI:10.23937/2572-407X.1510002

Growth-Differentiation Factor-15 at Risk Stratification in Diabetes Patients: Usefulness, Discrepancies, and Hype

Alexander E. Berezin

Article Type: Mini Review | First Published: September 17, 2015

Growth differentiation factor-15 (GDF-15) is a stress-responsive cytokine, which belongs to super family of the transforming growth factor beta. GDF-15 is widely presented in the various cells (macrophages, vascular smooth muscle cells, adipocytes, cardiomyocytes, endothelial cells, fibroblasts), tissues (adipose tissue, vessels, tissues of central and peripheral nervous system) and organs (heart, brain, liver, placenta) and it plays an important role in the regulation of the inflammatory respon...
 

 Open Access DOI:10.23937/2572-407X.1510001

Energy Intake, Dietary Habits and Life Style in Obese School Children with Dyslipidemia in the UAE

Asma Deeb, Rawan Al Hazaimeh, Salima Attia, Abubaker ElFatih, Omar Afandi and Nico Nagelkerke

Article Type: Original Article | First Published: May 28, 2015

The incidence of obesity in children is increasing. In the United Arab Emirates (UAE), childhood overweight and obesity reached up to 25% of the population. In addition, UAE has become one of the highest countries in the prevalence of type 2 diabetes. Various forms of life style behavior and dietary habits have contributed to obesity and the development of the metabolic syndrome. We aim to study energy intake, dietary habits and life style behavior in obese children with dyslipidemia in the UAE ...

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ClinMed Journals Index Copernicus Values

Clinical Medical Image Library: 93.51

International Journal of Critical Care and Emergency Medicine: 92.83

International Journal of Sports and Exercise Medicine: 91.84

International Journal of Womens Health and Wellness: 91.79

Journal of Musculoskeletal Disorders and Treatment: 91.73

Journal of Geriatric Medicine and Gerontology: 91.55

Journal of Infectious Diseases and Epidemiology: 91.55

Clinical Medical Reviews and Case Reports: 91.40

International Archives of Nursing and Health Care: 90.87

International Journal of Ophthalmology and Clinical Research: 90.80

International Archives of Urology and Complications: 90.73

Journal of Clinical Nephrology and Renal Care: 90.33

Journal of Family Medicine and Disease Prevention: 89.99

Journal of Clinical Gastroenterology and Treatment: 89.54

Journal of Dermatology Research and Therapy: 89.34

International Journal of Clinical Cardiology: 89.24

International Journal of Radiology and Imaging Technology: 88.88

Obstetrics and Gynaecology Cases - Reviews: 88.42

International Journal of Blood Research and Disorders: 88.22

International Journal of Diabetes and Clinical Research: 87.97




New Issues

VOLUME 8, ISSUE 2

International Journal of Clinical Cardiology

ISSN: 2378-2951 | ICV: 89.24

VOLUME 8 | ISSUE 2 | 2021

VOLUME 8, ISSUE 2

Obstetrics and Gynaecology Cases - Reviews

ISSN: 2377-9004 | ICV: 88.42

VOLUME 8 | ISSUE 2 | 2021

VOLUME 7, ISSUE 1

Journal of Hypertension and Management

ISSN: 2474-3690 | ICV: 87.69

VOLUME 7 | ISSUE 1 | 2021

VOLUME 8, ISSUE 2

International Journal of Diabetes and Clinical Research

ISSN: 2377-3634 | ICV: 87.97

VOLUME 8 | ISSUE 2 | 2021

VOLUME 7, ISSUE 4

Journal of Infectious Diseases and Epidemiology

ISSN: 2474-3658 | ICV: 91.55

VOLUME 7 | ISSUE 4 | 2021