International Journal of

Stem Cell Research & TherapyISSN: 2469-570X


 Open Access DOI:10.23937/2469-570X/1410077

Mesenchymal Stem Cell Applications for the Treatment of COVID-19: Clinical Perspective

Begüm Nisa Kasapli, Şimal Tepe, Tunahan Geçit, Esra Albayrak and Melek Yüce

Article Type: Review Article | First Published: December 10, 2022

COVID-19, caused by the new Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), causing a global pandemic, causes severe tissue damage and death. The leading pathophysiology of COVID-19, which affects many organs, especially the lungs, is severe acute respiratory distress syndrome (ARDS), and respiratory failure due to ARDS is the main cause of death. Mesenchymal stem/ stromal cells (MSCs) show multipotent differentiation property....

 Open Access DOI:10.23937/2469-570X/1410076

Prospective Safety and Efficacy Study for the Use of Adipose Derived Cellular Therapy in Degenerative Lumbar Spine Disorders

Khoshal Latifzai MD, Mark Berman MD, Sean Berman MS, Elliot Lander MD and Vassily T Eliopoulos MD

Article Type: Original Article | First Published: October 13, 2022

Low back pain is a significant cause of dis- ability worldwide. This study looks at the safety and efficacy of Autologous Adipose Derived Cellular Therapy in the form of Stromal Vascular Fraction (SVF) as a minimally invasive treatment option for low back pain. This is a prospective, patient funded, IRB ap- proved study looking at 549 patients who suffered from low back pain related to degenerative spinal conditions....

 Open Access DOI:10.23937/2469-570X/1410075

Treatment of a Chronic Obstructive Pulmonary Disease Case with Regentime® Procedure

Rita Boulos, Lea Nemer, Vanessa Mansou and Nassim Abi Chahine

Article Type: Case Report | First Published: September 23, 2022

Chronic Obstructive Pulmonary Disease (COPD) is a common disease associated with high morbidity and mortality rates. It is characterized by airway and parenchymal inflammation leading to airway narrowing, decreased lung recoil, and eventual airflow limitation. Despite the advance in therapeutic approaches, no curative clinical treatment for COPD exists. We present the case of a 74-year- old gentleman diagnosed with COPD who underwent stem cell therapy with the Regentime® Procedure....

 Open Access DOI:10.23937/2469-570X/1410074

Development of Robust Cell Therapy Manufacturing Processes Largely Depends on the Choice of Cell Counting Method Considering Cell Type, Precision, and Accuracy Requirements

Saedeh Dadgar, Vinitha Mary Kuruvilla, Haritha Duvvuru, Sahana Suresh Babu, Justin Beller and Ahmadian Baghbaderani Behnam

Article Type: Research Article | First Published: September 23, 2022

Universal to all cell therapies (CT) is the need to determine the number of cells at each step of the manufacturing process as they are processed in different unit operations and developed into clinically relevant final CT products. Identifying a precise and accurate cell counting method considering the cell type and application is crucial for the development of robust and reliable manufacturing processes, product characterization, and eventually commercialization of the cell therapies....

Volume 9
Issue 1