Treating Diabetic Peripheral Neuropathy Using a Novel, Nanotechnology-Based Topical Formulation to Improve Pain, Sensitivity, and Function
Jeffery LaMour, DPM, Douglas Grimm, DPM, Ester Smith, PhD, Zvi Yaniv, PhD and Peter Hurwitz
Article Type: Original Research | First Published: September 24, 2021
Diabetes has become one of the largest global healthcare problems of the 21st century. More than 100 million U.S. adults are now living with diabetes or pre-diabetes. The Centers for Disease Control and Prevention (CDC) reports that as of 2015, 30.3 million Americans (9.4% of the U.S. population) have diabetes and 1.5 million Americans are diagnosed with diabetes every year. The population prevalence of diabetes in the US is approaching 10% and is increasing by 5% each year. Annual costs for dia...
Prevalence, Contributing Factors and Management Strategies (Self-Management Education) of Type 2 Diabetes Patients in Nigeria: A Review
Emos E Tella, Ismaeel Yunusa, Judith H Hassan, Ibrahim A Chindo and Victor B Oti
Article Type: Review Article | First Published: September 17, 2021
Diabetes is one of the major causes of morbidity and premature mortality globally with over 371 million people worldwide and more than 80% of morbidity and mortality due to diabetes occurred in the low- and middle-income countries (LMICs) including Nigeria, which has the highest burden of diabetes in Africa. The high number of medical admissions and deaths (15% and 22%) due to diabetes complications in Nigeria reflect the poor quality of care. Therefore, this review aims to discuss the prevalenc...
Clinical Characteristics and Outcome of COVID-19 among People Living with Diabetes in Nigeria
Vivian Gga Kwaghe, Rifkatu Reng, Olufemi Adediran and Felicia Anumah
Article Type: Original Article | First Published: August 28, 2021
The novel coronavirus disease 2019 (COVID-19) has affected millions of people globally with over 3 million deaths. People with underlying comorbidities are at a risk of having severe disease with increased fatality. This study aimed at describing the clinical characteristics and outcome of COVID-19 among people living with diabetes mellitus (DM) in Nigeria. This was a retrospective study that analyzed the data of adult patients who were admitted into the isolation and treatment center at the Uni...
Oral Semaglutide: A Novel Oral Preparation of GLP-1 Receptor Agonist
Priya Mohan Babu and Vinay Eligar
Article Type: Review Article | First Published: August 07, 2021
The glucagon-like peptide-1 (GLP-1) is an endogenous hormone produced by the L cells in the intestine. It is released in response to the intake of food and intestinal dilatation. It stimulates the pancreatic beta-cell to secrete insulin which is dependent upon ingestion of food. GLP-1 acts to slow down gastric motility and suppress appetite through the GLP-1 receptors in the satiety center. It is neutralized by the dipeptidyl peptidase-4 (DPP-4) enzyme very quickly. Hence the endogenous GLP-1 ha...
Effect of Educational Intervention Programme on Self- Management Practices of Individuals with Type 2 Diabetes Mellitus in South-East, Nigeria
Christiana Nkiru Okafor, PhD, Pauline Ojinaka Ezenduka, PhD, Chinedu Charles Onyenekwe, PhD, Kenneth Umezulike Ani, BMR (PT), M.Sc, Chika Chioma H Odira, PhD, Adaobi Maryann Ibekwe, PhD and Vera Ijeoma Onyekaonwu, M.Sc
Article Type: Original Research Article | First Published: July 31, 2021
Diabetes mellitus (DM) is a chronic disease that has great impact on health and affects quality of life of DM sufferers. Despite its chronic nature, DM is also a self managed disease that requires adequate knowledge of DM self management, in order for the sufferers to actively participate in their self care. The study was aimed at determining the effect of educational intervention programme on the selfmanagement practices of persons with type 2 diabetes (T2DM) in South East, Nigeria. A quasi ex...