Current Issue

Review Article Open Access

Sleep Disturbance as a Contributor to Pediatric Obesity: Implications and Screening

Gitanjali Srivastava, Valerie O'Hara and Nancy Browne
J Sleep Disord Manag Volume 4, Issue 1

Abstract: Obesity causes more than 200 medical disorders including cardiovascular disease, diabetes, hypertension, sleep apnea. In particular, the prevalence and rate of obesity in children and adolescents have increased with over 1/3 of the US pediatric population afflicted with overweight and obesity. Though there is a multifactorial etiology including complex biological and physiological mechanisms involved in energy regulation that may predispose toward an obesity phenotype, we highlight an often missed and overlooked etiology of obesity in clinical assessment in children- sleep disturbance and its causation to weight gain.

PDF   Full Text   DOI: 10.23937/2572-4053.1510019

Research Article Open Access

Corticosterone Response in Sleep Deprivation and Sleep Fragmentation

Yonglin Gao, Brandon Akers, Michael B Roberts and Rif S El-Mallakh
J Sleep Disord Manag Volume 3, Issue 1

Abstract: Rapid Eye Movement (REM) sleep deprivation is understood to be associated with more severe negative effects than REM fragmentation. Comparison of the corticosterone response between these patterns of sleep disruption has not been well characterized. Black Swiss mice were exposed to 1-day and 3-day periods of REM deprivation with inverted flower-pot method or REM fragmentation using the moving bar method.

PDF   Full Text   DOI: 10.23937/2572-4053.1510018

Case Report Open Access

Sleep, Nightmares and Schizophrenia

Mary V Seeman
J Sleep Disord Manag Volume 3, Issue 1

Abstract: Sleep problems are recognized as widespread in patients with psychosis. Other facts are known as well - that not only can psychiatric illness result in sleep problems, but that these same problems can exacerbate psychopathology and that they constitute risk factors for suicide.

PDF   Full Text   DOI: 10.23937/2572-4053.1510017

Research Article Open Access

Valeriana Officinalis and Melissa Officinalis Extracts Normalize Brain Levels of GABA and Glutamate Altered by Chronic Stress

Francesco Scaglione and Andrea Zangara
J Sleep Disord Manag Volume 3, Issue 1

Abstract: Despite being traditionally used herbals to treat mild anxiety and sleep disorders, Valeriana officinalis and Melissa officinalis mechanism of action is not fully understood. While the pattern of mood modulation of both herbals suggests the involvement of the Gamma-Aminobutyric Acid (GABA) ergic system, other changes in the neurotransmitters pathways can provide an explanation for the clinical effects.

PDF   Full Text   DOI: 10.23937/2572-4053.1510016

Case Report Open Access

Polycystic Ovarian Syndrome and Narcolepsy: A Coincidental Relationship?

Danielle Lee, Bishoy Kolta and Karim Sedky
J Sleep Disord Manag Volume 3, Issue 1

Abstract: A relationship between Polycystic Ovarian Syndrome (PCOS) and narcolepsy have not been well examined. Both disorders share common co morbidities including obesity, Obstructive Sleep Apnea (OSA), and Excessive Daytime Sleepiness (EDS).

PDF   Full Text   DOI: 10.23937/2572-4053.1510015

Research Article Open Access

Biomimetic Oral Appliance Therapy in Adults with Mild to Moderate Obstructive Sleep Apnea Using Combined Maxillo-Mandibular Correction

G Dave Singh and Samuel E Cress
J Sleep Disord Manag Volume 3, Issue 1

Abstract: Although mandibular advancement devices (MADs) are utilized for the management of mild to moderate OSA, there are concerns about temporo-mandibular joint (TMJ) issues. Biomimetic oral appliance therapy (BOAT) differs from MADs as it aims to achieve midfacial redevelopment in combination with mandibular repositioning. In this study, we tested the hypothesis that mild to moderate cases of OSA can be addressed with combined maxillo-mandibular correction using BOAT.

PDF   Full Text   DOI: 10.23937/2572-4053.1510014

Volume 3
Issue 1