Journal of Sleep Disorders and Management is a global, peer-reviewed, open access journal focused on clinical, preventative, curative and social aspects of Sleep Medicine. The main objective of the journal is to set a forum for publication, education, and exchange of opinions globally. The Journal provides a podium for all clinicians, surgeons and health professionals to contribute their findings and help raise awareness among the community on Sleep Medicine. We aim to publish the highest quality clinical content via open access platform providing the readers free, immediate and unlimited access.
Journal of Sleep Disorders and Management is an open journal provides research updates on Advanced Sleep Phase Disorder, Bruxism, Deserted Sleep Phase Disorder, Hypopnea Syndrome, Idiopathic Hypersomnia, Narcolepsy, Neuropsychology, Night Terror, Nocturia, Parasomnias, Periodic Limb Movement Disorder, Primary Insomnia, Rapid Eye Movement Behavior Disorder, Restless Legs Syndrome, Shift Work Sleep Disorder, Sleep Apnea, Sleep Medicines, Sleep Paralysis, Sleepwalking or Somnambulism, Somniphobia, etc. Original Article, Reviews, Mini-Reviews, Short Communications, Case Reports, Perspectives/Opinions, Letters, Short Note, and Commentaries are accepted for publication. All articles published in the journal are subject to a rigorous peer review process. It encourages authors to publish their work in detail to disseminate the updated research findings.
Articles Search by Keyword | Journal title | Author name | DOI
Open Access DOI:10.23937/2572-4053.1510036
Tolga Dogan, PhD, Baris Sensoy, PhD and Aygul Gunes, PhD
Article Type: Original Article | First Published: October 25, 2021
The aim of this study was to evaluate the relationship of regional selectivity in coronary arteries with OSAS severity using the Syntax (SX) score in OSAS (Obstructive sleep apnea syndrome) patients. This retrospective study included 68 OSAS patients with coronary artery disease (CAD) who were followed up at Cardiology and Neurology Outpatient Clinic in our hospital between January 2019 and October 2020. Patients with previously diagnosed OSAS were separated into 2 groups as mild-moderate OSAS g...
Open Access DOI:10.23937/2572-4053.1510035
Alberto Labra, MD, Reyes Haro-Valencia, PhD, Montserrat Roldán-Navarro, MS, Mauricio Ruiz-Morales, MD and Francisco Sánchez-Narváez, PhD
Article Type: Original Article | First Published: September 30, 2021
Obstructive Sleep Apnea Syndrome (OSAS) is a consequence of a reduced area at the upper respiratory tract that leads to obstruction and cessation of airflow, causing oxygen desaturation and fragmentation of the sleep architecture. Between 60 and 70% of patients with OSAS are obese. We present a longitudinal, prospective, observational and analytical study. A sample of 89 patients with a polysomnographic diagnosis of OSAS was studied. The following anthropometric variables were determined: Neck C...
Open Access DOI:10.23937/2572-4053.1510034
Danielle Tran, BS, Christopher Tang, BS, Sanam Tabatabai, BS, Devon Pleasants, BS, Christopher Choukalas, MD, MS, Jie Min, MS, Quyen Do, MS, Laura Sands, PhD, Kathryn Lee, RN, PhD and Jacqueline M Leung, MD, MPH
Article Type: Original Investigation | First Published: August 16, 2021
Sleep disruption is prevalent in older patients. No previous studies have considered the impact of surgery duration or surgery end time of day on postoperative sleep disruption. Accordingly, we examined the duration of surgery and surgery end times for associations with postoperative sleep disruption. Inclusion criteria were patients ≥ 65 years of age undergoing major, non-cardiac surgery. Sleep disruption was measured by wrist actigraphy and defined as wake after sleep onset (WASO) during the...
Open Access DOI:10.23937/2572-4053.1510033
Marcel Braun, MBA, Sarah Dietz-Terjung, BSc, MSc, Christian Taube, MD, PhD and Christoph Schoebel, MD
Article Type: Original Article | First Published: April 21, 2021
Understanding of patient preferences is increasingly seen as an important factor to improve the effectiveness of care, especially in chronic conditions such as obstructive sleep apnea (OSA). Evidence of preferences of patients with OSA is still limited, though the disease is highly prevalent. Aim of the study was to improve understanding of the relevance of treatment attributes among OSA patients. Based on a structured questionnaire, the relevance of attributes of OSA treatments as well as willi...
Open Access DOI:10.23937/2572-4053.1510032
Vishwesh Agarwal, Deepak Goel, Vimal Kumar Paliwal, Latika Gupta, Akanksha Ghodke and Vikas Agarwal
Article Type: Original Article | First Published: January 23, 2021
Due to the COVID-19 pandemic outbreak most countries have resorted to enforced lockdowns. Being forced to stay home people are prone to succumb to various kind of stressors and may later develop psychological problems like anxiety, depression and insomnia. Taking advantage of this situation we developed a survey to study sleep disruptions due to prolonged isolation. An electronic survey developed using an online cloud-based website (Survey Monkey®) was served to general population. Participants...
Open Access DOI:10.23937/2572-4053.1510031
Carlos S Ruggeri, MD and Sebastian López
Article Type: Original Article | First Published: December 31, 2020
In sleep apnea/hypopnea syndrome (SAHS) a superior airway collapse can occur in the anteroposterioror lateral direction. The primary or secondary decrease in the tone of the dilating muscles of the pharynx, due to the negative pressure produced by the contraction of the diaphragm cause the collapse. Pharyngoplasty surgical techniques try to improve lateral collapse by repositioning the muscles that constitute the pharyngeal lateral wall, mainly the palatopharyngeal (PP), palatoglossal (PG) and u...
Open Access DOI:10.23937/2572-4053.1510030
Cristina Anna Maria Lo Iacono, Enrico Reali, Paolo Perciballi and Mauro Cacciafesta
Article Type: Short Comunication | First Published: November 18, 2020
Obstructive sleep apnea (OSA) is a sleep respiratory disorder characterized by an intermittent complete or partial collapse of the upper airways, resulting in apnea and hypopnea events. Breathing pauses cause acute adverse effects including oxyhemoglobin desaturation, changes in blood pressure and heart rate, increased sympathetic activity, cortical arousals (micro awakenings) and sleep fragmentation. There is limited evidence to support the fact that mild OSA can have negative health consequenc...
Open Access DOI:10.23937/2572-4053.1510029
Article Type: Case Report | First Published: November 14, 2020
Obstructive sleep apnea is a disease consisting of episodes of partial or complete closure of the upper airway that occur during sleep and lead to breathing cessation defined as a period of apnea more than 10s. Symptom include restlessness, snoring, recurrent awakening, morning headache and excessive day time sleepiness. Diagnosis of obstructive sleep apnea is based on sleep history and polysomnography. Continuous positive airway pressure (CPAP) is the gold-standard treatment in severe OSAS. In ...
Open Access DOI:10.23937/2572-4053.1510028
Susan K Sebastian, MS, Ankur Sharma, MS, Omprakash Chawla, MS and Payal Garg, MS
Article Type: Retrospective Study | First Published: July 04, 2020
Twenty four patients with evidence of OSA on polysomnography were included. In all patients the major cause of obstruction was due to concentric collapse of velopharynx as evidenced on Muller Maneuver (MM) and Drug Induced Sleep Endoscopy (DISE). All had non-adherence to (CPAP) therapy and underwent Barbed Palato Pharyngoplasty (BPP) for correction of concentric collapse of velum. Apnoea-Hypopnoea Index (AHI), Lowest Oxygen Saturation (L-sat), Epworth Sleepiness Score (ESS), Visual Analog Score ...
Open Access DOI:10.23937/2572-4053.1510027
Behrooz Kamgar-Parsi, PhD
Article Type: Commentary | First Published: December 30, 2019
Despite earlier reports of success, controlled studies have not confirmed the effectiveness of vitamin B12 in treating circadian rhythm sleep disorders. We try to explain why these two types of studies do not produce similar results. Individuals with circadian rhythm sleep disorder suffer from recurrent patterns of disrupted sleep that can significantly affect their daily functioning. Evidence suggests that vitamin B12 supplements may have a beneficial effect on sleep patterns. However, researc...
Open Access DOI:10.23937/2572-4053.1510026
John Arek Kileci, Derya Arkonac, Leslie Seijo and Alfredo Astua
Article Type: Research Article | First Published: August 28, 2019
Obstructive Sleep Apnea (OSA) is a complex disease process with a known significant association with cardiovascular diseases and the metabolic syndrome. This study aimed to define phenotypes of OSA based on sleep studies and cardiovascular comorbidities and to further investigate whether there would be any meaningful association between these disease processes. Defining phenotypes could assist in individual targeted treatments for patients with OSA....
Open Access DOI:10.23937/2572-4053.1510025
Magdalena Deaton, MPH, MSN, RN, AGNP-C, Jeanne Ruff, MPH, BSN, RN and Lisa Boss, PhD, RN, CNS, CEN, CNE
Article Type: Research Article | First Published: July 26, 2019
Hypertension (HTN) and obstructive sleep apnea (OSA) are associated with increased risk for adverse cardiovascular events. Comorbid HTN with OSA is often resistant to pharmacologic treatment. Chronotherapy, the timing of treatment based on circadian rhythms, may prove to be a valuable, cost-effective tool for improving blood pressure (BP) control among those with OSA. This Systematic Review appraises the existing literature regarding morning (a.m.) vs. evening (p.m.) administration of antihypert...
Open Access DOI:10.23937/2572-4053.1510024
Isabel Loucao Amorim, MD, Linda Azevedo Kauppila, MD, Mariana Reis Costa, MD, Carla Bentes, MD, PhD, and Rita Peralta, MD
Article Type: Case Report | First Published: July 06, 2019
REM sleep behavior disorder shares some clinical similarities with nocturnal epileptic seizures, which can result in misdiagnosis. We report a case of a man with Parkinson Disease diagnosis and parietal and frontal meningiomas who started to have abnormal sleep behaviors, suggestive of REM sleep behavior disorder. Video-polysomnographic showed periodic bilateral occipital epileptiform activity that occurred near arousals, where subtle movements were detected. During REM sleep no loss of atonia n...
Open Access DOI:10.23937/2572-4053.1510023
Melrose Truett Garrett, Jr. Sc.D
Article Type: Short Note | First Published: June 24, 2019
RLS accompanying loose stool (not diarrhea) indicated two hypotheses: 1) Medications for diarrhea will relieve RLS, 2) RLS is caused by pressure in the colon blocking a femoral vein, the nervous system then causes muscle contraction in the leg. In tests both were sustained. Soluble fiber corrects loose bowels but the number of Americans with insufficient fiber is much greater than those with RLS....
Open Access DOI:10.23937/2572-4053.1510022
Jonathan Greenburg, DDS, Jesse Cozean, MBA and Colette Cozean, PhD
Article Type: Clinical Trial | First Published: June 10, 2019
Habitual snoring affects millions of individuals and their partners, but often goes unresolved due to the high cost of care and other barriers to treatment. The purpose of this study was to evaluate the effectiveness of a novel intraoral device that restrains the tongue in an overthe- counter setting in a population of habitual snorers. Individuals who self-reported snoring enrolled in the study and were sent an investigational device. After signing the informed consent, they completed an initia...
Open Access DOI:10.23937/2572-4053.1510021
Natalia Pinho de Oliveira Ribeiro, Alexandre Rafael de Mello Schier, Christina Maria Pinho de Oliveira and Adriana Cardoso Silva
Article Type: Case Report | First Published: May 27, 2019
Rheumatoid arthritis (RA) is an autoimmune disease. RA patients may undertake traditional therapy with antidepressants to control the depressive symptoms and to reduce their pain levels. This is the case of a patient with RA who presented with tactile hallucinations. On the second day of the pain crisis, the RA patient used agomelatine and a painkiller and showed symptoms of tactile hallucination. This is the first report of tactile hallucinations in this context....
Open Access DOI:10.23937/2572-4053.1510020
Chu Qin PHUA, Yi Rong Leonora LIU, Pei Yuan FONG, Kay Yee Winnie FUNG and Kun Kiaang Henry TAN
Article Type: Retrospective study | First Published: April 29, 2019
The commonest cause of paediatric obstructive sleep apnoea (OSA) is the disproportionate adenotonsillar hypertrophy in relation to craniofacial growth and airway calibre. In recent years, there is an increasing awareness of paediatric OSA, leading to increasing number of adenotonsillectomy being performed for this indication. Adenotonsillectomy has been shown to confer improvement in child behaviour and quality of life. In up to 79% of patients, it can lead to normalisation of polysomnography......
Open Access DOI:10.23937/2572-4053.1510019
Gitanjali Srivastava, Valerie O'Hara and Nancy Browne
Article Type: Review Article | First Published: July 16, 2018
Obesity causes more than 200 medical disorders including cardiovascular disease, diabetes, hypertension, sleep apnea. In particular, the prevalence and rate of obesity in children and adolescents have increased with over 1/3 of the US pediatric population afflicted with overweight and obesity. Though there is a multifactorial etiology including complex biological and physiological mechanisms involved in energy regulation that may predispose toward an obesity phenotype, we highlight an often miss...
Open Access DOI:10.23937/2572-4053.1510018
Yonglin Gao, Brandon Akers, Michael B Roberts and Rif S El-Mallakh
Article Type: Research Article | First Published: December 23, 2017
Rapid Eye Movement (REM) sleep deprivation is understood to be associated with more severe negative effects than REM fragmentation. Comparison of the corticosterone response between these patterns of sleep disruption has not been well characterized. Black Swiss mice were exposed to 1-day and 3-day periods of REM deprivation with inverted flower-pot method or REM fragmentation using the moving bar method. ...
Open Access DOI:10.23937/2572-4053.1510017
Mary V Seeman
Article Type: Case Report | First Published: October 19, 2017
Sleep problems are recognized as widespread in patients with psychosis. Other facts are known as well - that not only can psychiatric illness result in sleep problems, but that these same problems can exacerbate psychopathology and that they constitute risk factors for suicide....
Open Access DOI:10.23937/2572-4053.1510016
Francesco Scaglione and Andrea Zangara
Article Type: Research Article | First Published: September 18, 2017
Despite being traditionally used herbals to treat mild anxiety and sleep disorders, Valeriana officinalis and Melissa officinalis mechanism of action is not fully understood. While the pattern of mood modulation of both herbals suggests the involvement of the Gamma-Aminobutyric Acid (GABA) ergic system, other changes in the neurotransmitters pathways can provide an explanation for the clinical effects....
Open Access DOI:10.23937/2572-4053.1510015
Danielle Lee, Bishoy Kolta and Karim Sedky
Article Type: Case Report | First Published: June 28, 2017
A relationship between Polycystic Ovarian Syndrome (PCOS) and narcolepsy have not been well examined. Both disorders share common co morbidities including obesity, Obstructive Sleep Apnea (OSA), and Excessive Daytime Sleepiness (EDS). ...
Open Access DOI:10.23937/2572-4053.1510014
G Dave Singh and Samuel E Cress
Article Type: Research Article | First Published: March 17, 2017
Although mandibular advancement devices (MADs) are utilized for the management of mild to moderate OSA, there are concerns about temporo-mandibular joint (TMJ) issues. Biomimetic oral appliance therapy (BOAT) differs from MADs as it aims to achieve midfacial redevelopment in combination with mandibular repositioning. In this study, we tested the hypothesis that mild to moderate cases of OSA can be addressed with combined maxillo-mandibular correction using BOAT....
Open Access DOI:10.23937/2572-4053.1510013
Ama Johal, Preeti Jahaur, Fatemah Alqattan, Saba Kassim and Kieran Mc Cloughlin
Article Type: Original Article | First Published: November 05, 2016
A long-term prospective observational study was undertaken in which patients with moderate OSAHS and in whom CPAP use had failed, to determine treatment compliance with MAA therapy, after a minimum period of 18 months, using an objective monitor. Treatment outcomes included both objective sleep monitoring and a determination of the therapeutic efficacy based on the calculation of the mean disease alleviation (MDA)....
Open Access DOI:10.23937/2572-4053.1510012
Juliana S Ee, Cristobal S Berry-Caban, Dana R Nguyen, Madina Boyd, Nick Bennett, Thomas Beltran and Michele Williams
Article Type: Research Article | First Published: October 20, 2016
nsomnia is a highly prevalent sleep disorder in the US. Among the military population, 41% of active duty service members reported less than 5 hours sleep per night, and there was nearly a 20-fold increase in incidence of insomnia among service members between 2000 and 2009. Given that most soldiers with insomnia seek initial treatment in the primary care setting, an understanding of soldiers' treatment expectations and preferences may contribute to treatment success....
Open Access DOI:10.23937/2572-4053.1510011
Meritxell Espuga, Maria Antonia Ramon PT, Alfons Ayora, Manuel Alonso, Gabriel Sampol, Guadalupe Silveira and Patricia Lloberes
Article Type: Research Article | First Published: July 28, 2016
The aim of the study is to assess the sleep habits and prevalence of excessive daytime sleepiness (EDS) in Spanish health care workers and the relationship between sleep habits, EDS, anthropometric measurements, work shift, sleep apnea risk, and work commute traffic accidents....
Open Access DOI:10.23937/2572-4053.1510010
Beate Stubbe, Thomas Penzel, Ingo Fietze, Anne Obst, Carmen Garcia, Sandra Zimmermann, Beate Diecker, Martin Glos, Carsten Oliver Schmidt, Katharina Lau, Michael Piontek, Katrin Hegenscheid, Johannes Dober, Klaus Berger, Andras Szentkiralyi, Stephan B. Felix, Christoph Schaper, Sven Glaser, Henry Volzke and Ralf Ewert
Article Type: Research Article | First Published: June 02, 2016
The Study of Health in Pomerania (SHIP) consists of two independent population-based prospective subcohorts. The core diagnostic program of the baseline SHIP-TREND included the assessment of risk behaviour, common chronic diseases, cardiac, vascular, pulmonary, and serum blood parameters, mental health, and cognitive functioning. Genotyping and whole-body MRI were also performed. In addition, all participants were offered a standard overnight laboratory-based polysomnography (PSG). Subjective sl...
Open Access DOI:10.23937/2572-4053.1510009
Cigdem Akyol Beyoglu
Article Type: Review Article | First Published: February 25, 2016
The aim of this manuscript is to determine perioperative management of patients with obstructive sleep apnea. Obstructive sleep apnea (OSA) may cause postoperative complications related to upper airway collapse and cardiopulmonary system. Treatment with continue positive airway pressure (CPAP) may offer high standards of living to the patients and may protect them against postoperative complications. Long-acting and potent opioids may cause postoperative airway collapse in this population....
Open Access DOI:10.23937/2572-4053.1510008
Gregory John Vitale, Kimberly Capp, Kimberly Ethridge, Maggie S. Lorenzetti, Mary Jeffrey, John Skicki and Ashley Stripling
Article Type: Review Article | First Published: February 10, 2016
Sleep apnea research has become increasingly relevant to the field of psychology. Although the physiological sequelae have been researched extensively, and treatment options are now available for those diagnosed, much is left to be done. Specifically, to date, the cognitive and psychological consequences of sleep apnea have received less attention. As such, this paper serves to review the current state of the literature and presents relevant neuropsychological and emotional domains....
Open Access DOI:10.23937/2572-4053.1510007
Michelle B Collier, Stephanie D Nichols and John J Campbell
Article Type: Case Report | First Published: December 01, 2015
Unlike dyssomnias that influence quality and duration of sleep, parasomnias primarily affect behavior. Rapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia characterized by loss of normal skeletal muscle atonia during REM sleep. Usually, atonia occurs through neural inhibition via pontine nuclei to spinal motor neurons. Dysfunction, due to lesions or neurodegeneration, can lead to dream enactment. Therefore, sleepers may act violently, including: hitting, jumping, or kicking......
Open Access DOI:10.23937/2572-4053.1510006
Angelika A. Schlarb, Isabel Bihlmaier, Martin Hautzinger, Marco D. Gulewitsch and Barbara Schwerdtle
Article Type: Research Article | First Published: October 27,2015
Sleep problems are a common complaint among adults. In university students international studies showed prevalence rates between 4.7 and 36.2% for sleep difficulties and 2-3% of students report nightmares. Previous studies show that nightmares are often associated with insomnia and mental strain, but also with gender. The goal of this study was to outline nightmares, associations with sleep disturbances and mental strain as well as self-efficacy among university students. An amount of 2196 stude...
Open Access DOI:10.23937/2572-4053.1510005
Flora Bat-Pitault, Christine Deruelle, Sophie Flori, Veronique Porcher-Guinet, Camille Stagnara, Aurore Guyon, Sabine Plancoulaine, Joelle Adrien, David Da Fonseca, Hugues Patural and Patricia Franco
Article Type: Original Article | First Published: September 26, 2015
217 women recruited in childbirth in the maternity participated in the survey with 34 included in the MDD group. 17 among the MDD group were diagnosed PPMD. Sleep characteristics of women were assessed before and during pregnancy with self-administered questionnaires and depressive symptoms after delivery were screen with the hospital anxiety depression scale (HAD). Diagnosis of depression was performed according to DSM-IV criteria during a semi-structured interview done by phone....
Open Access DOI:10.23937/2572-4053.1510004
Che Wankie, D. Kritz-Silverstein, E. Barrett-Connor and D.M. Kado
Article Type: Original Article | First Published: September 21, 2015
Accentuated kyphosis, popularly known as the dowager's hump, is a forward curvature of the thoracic spine that appears as a humped or crooked back. Progressive kyphosis may develop as a result of spinal fractures caused by osteoporosis, postural changes due to muscle weakness, and/or degenerative disc disease. Hyperkyphosis is a common condition affecting 20-40% of older persons, but can occur less commonly among the young. In older persons, hyperkyphosis has been associated with falls, fracture...
Open Access DOI:10.23937/2572-4053.1510003
Fructuoso Ayala-Guerrero and Graciela Mexicano
Article Type: Research Article | First Published: September 14, 2015
The sleep patterns of ten blind adults and their matched controls were studied during three consecutive nights. The first night was allowed for adaptation. Significant electroencephalographic and quantitative findings were obtained from nights 2 and 3. Although alpha-like rhythm was registered in only one blind subject during wakefulness, it was displayed by 8 of the 10 blind participants of this study during REM sleep. This rhythm was also present during the N2 sleep stage. The delta phase of s...
Open Access DOI:10.23937/2572-4053.1510002
Nirosha J. Murugan, Nicolas Rouleau, Lukasz M. Karbowski, Andrew P. Lapointe and Michael A. Persinger
Article Type: Case Report | First Published: September 10, 2015
Quantitative electroencephalographic (QEEG) measurements were completed for a 35 year old of paramedic following two to five days of shift change and rest periods. The most conspicuous and reliable change was a marked increase (factor of 5) in power within the alpha band over the left prefrontal region and, to a lesser degree, increased power within the low-beta band over the right parietal region during the test periods after no work days. These results indicate that regions of cerebral cortice...
Open Access DOI:10.23937/2572-4053.1510001
Silvia Cerolini, Andrea Ballesio and Caterina Lombardo
Article Type: Review Article | First Published: August 28, 2015
Recent findings suggest that insomnia and emotion regulation are closely connected. Insomnia is widely associated with medical and psychiatric conditions as well as with impaired quality of life and emotional functioning. Additionally empirical evidence suggests that emotional dysregulation plays a crucial role in the onset and maintenance of psychopathological disorders. Although these seem to interact, very few studies investigated the relationship between disturbed sleep and problems in emoti...
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