Global Impacts of Legalization and Decriminalization of Marijuana and Cannabis
Karen Mollner, MPAS, MS, PA-C
Article Type: Research Article | First Published: August 25, 2022
The purpose of this article is to discuss global public health impacts of legalization and decriminalization of marijuana and cannabis regarding physical and mental health impacts as well as accident and death reports. Extensive review of the current medical literature was performed with a focus on papers discussing medical effects from marijuana use, public health impacts from legalization and decriminalization of marijuana and accident and death reports in various countries after legalization ...
In vitro and in vivo Evaluation of the Toxicity Roots of Leptadenia hastata (PER) Decne. Cytotoxicity on Caco2 and HepG2 Cells, Acute and Sub-acute Toxicity on Wistar Rats
Fatoumata Bah, Pascale Marie Aimée Dozolme, Mama Sy Diallo, Ramadhan Nyandwi, Mohamadou Lamine Daffé, Aminata Touré, Absa Lam, Mathilde Cabral, MatarSeck, Serge Maria Moukha and Mamadou Fall
Article Type: Research Article | First Published: August 10, 2022
Nowadays, the use of medicinal plants, for treatment of several pathologies, continues to gain grounds throughout the world. Leptadenia hastata, like other medicinal plants, is used as therapeutic agent for several pathological conditions including diabetes mellitus, diarrhoea, and prostatitis, among other, however, limited data on its toxicity are available....
Meta-Analyses of Glyphosate and Non-Hodgkin’s Lymphoma: Expert Panel Conclusions and Recommendations
Kirman CR, Cocco P, Eslick GD, Villeneuve PJ and Hays SM
Article Type: Review Article | First Published: March 31, 2022
An expert panel was assembled to support a review of a series of recent publications using a modified Delphi format. These publications were scored based on a consideration of confidence in their methods, results, conclusions, and applicability to risk-based decision making. Mean confidence scores for the papers reviewed ranged from 53 to 74 (maximum score = 100), and key strengths and concerns were identified. This review highlights the need for transparency in meta-analyses. Different conclusi...
Cytotoxic Effects of Ceteareth-20 and Paraffinium Liquidum In Vitro
Duygu Kirkik, PhD, Fatih Hacimustafaoglu, PhD and Derya Altunkanat, PhD
Article Type: Research Article | First Published: March 31, 2022
The aim of this study is to investigate the effects of ceteareth-20 and paraffinium liquidium on cell viability and cytotoxicity in human lymphocyte in vitro. We studied the cytotoxic and inhibitory effects of ceteareth-20 and paraffinium liquidum on cell proliferation using lactate dehydrogenase (LDH) assay and cell proliferation (WST-1) assay. The cytotoxicity was enhanced when cells were treated with 1%, 5%, 25% and 50% paraffinium liquidium dilutions (p < 0.05). Moreover, cell number signifi...