International Archives of Medical Microbiology is an open access, peer reviewed, multidisciplinary journal dedicated to gather information on understanding the science of complex relationship between viral, bacterial or parasitic pathogens and the human host. Research is very rapidly growing in this field covering wide range of areas such as biomedical science including the molecular basis of disease, cancer biology, immunology and pathology. All published information is permanently archived and accessible under the attribution of Creative Commons Attribution License.
The journal gathers information via original, reviews, cases and other related type of articles gathered across the globe and are selectively published under various topics of general immunology, immunoglobulins, histocompatibility, humoral immunity, Ag-Ab reactions, cell mediated immunity, complement, hypersensitivity, immunological defects, antimicrobial chemotherapy, general microbiology, normal flora, gram-positive cocci: Staphylococcus, Streptococcus, gram-positive spore-formers: Bacillus, Clostridium; Anaerobic infections: bacteroides, gram-negative bacilli: Salmonella, Shigella, Escherichia, gram-negative bacilli: coliforms (Klebsiella, Proteus), Pseudomonas, gram-negative curved bacilli: Vibrio, Campylobacter, helicobacter, gram-negative coccobacilli: Brucella, Yersinia, Bordetella, fastidious gram-negative bacteria: Neisseria, Haemophilus, Legionella, gram-positive bacilli: Listeria, Corynebacteria, Mycobacteria, spirochetes: Treponema, Leptospira, Borrelia, obligate intracellular bacteria: Rickettsia, Chlamydia, mycotic infections, general virology; DNA viruses: Papillomavirus, Herpesvirus, Poxvirus; RNA viruses: Picornavirus, Hepatitis viruses, RNA Viruses: Togavirus, Rubella, Rhabdovirus; RNA viruses: Paramyxovirus, Orthomyxovirus; RNA viruses: Ebolavirus; RNA viruses: Retrovirus, etc.
Articles Search by Keyword | Journal title | Author name | DOI
Open Access DOI:10.23937/2643-4008/1710016
Joao Rodrigues dos Santos
Article Type: Research Article | First Published: November 16, 2022
Viruses invade the cell through a highly selective mechanism known as “Receptor-Mediated Endocytosis”. The virus's interaction with the target cell occurs via the formation of a vesicle that acts as a means of transport into the cell. Once internalized, the vesicle will originate an acidic organelle, containing digestive enzymes, called an endosome....
Open Access DOI:10.23937/2643-4008/1710015
Borré-Naranjo Diana, Cárdenas-Bolívar Yenny, Manzur-Barbur Maria Carolina, Toro Esteban, Buendía Emiro, Martínez Maria Cristina, Coronell Wilfrido and Dueñas-Castell Carmelo
Article Type: Review Article | First Published: September 01, 2022
Dengue is a very common viral infection in tropical zones, it is transmitted by vectors to humans by mosquito bites of the genre: Aedes. Oriental Mediterranean, Americas, Southeast Asia, Pacific, and Africa are all known as endemic zones for dengue. The treatment of severe dengue is based on the administration of intravenous fluids (IVF) and the management of complications....
Open Access DOI:10.23937/2643-4008/1710014
Article Type: Brief Note | First Published: October 25, 2021
Fungal infection caused by Candida auris is now a global crisis. However, its multidrug-resistant nature and onerous identification have left limited therapeutic options resulting in 30-60% mortality. Amphotericin-B (AmB), a broad-spectrum and a potent fungicidal with a rare resistance pattern, is considered a gold-standard antifungal drug. Yet, its antifungal potential is not fully recognized under the pretext of its potential nephrotoxicity. Liposomal AmB formulations are safer than AmB-Deoxyc...
Open Access DOI:10.23937/2643-4008/1710012
Jayasimha Rao, PhD, Adenike Adenikinju, MD, James M. Gray, MS, Lily Colpitts, MD, Alyson Prorock, BS, Yongde Bao, PhD, Thomas M. Kerkering, MD, Dorothy C. Garner, MD and Roderick V. Jensen, PhD
Article Type: Original Article | First Published: June 17, 2021
Multidrug-resistant (MDR) and virulent pathogenic strains of Pseudomonas aeruginosa (Pa) are among the most dangerous pathogens in healthcare-associated infections. In this study, a comparative analysis was performed on two clinical Pa strains from pneumonia patients, 1) An acute strain (CMC-115) and 2) A chronic multidrug- and carbapenemresistant strain (CMC-097) with distinct phenotypic and genetic characteristics. A transcriptome analysis using both the Pseudomonas DNA GeneChip microarray and...
Open Access DOI:10.23937/2643-4008/1710011
Abdlmanam Fakron, Idress Hamad Attitalla, Mohamed Younes A Hassan and Sumeet Dwivedi
Article Type: Review Article | First Published: April 30, 2021
Since photosynthesis is the primary process through which light energy absorbed and converted into organic matter, thus, plant chlorophyll pigment (forms A and B) plays an essential role in the progression absorbed solar energy and synthesis of organic matter in a plant. Therefore, this paper aims at the extent to which the optical activity of chlorophyll molecules monitored and methods (non-destructive and destructive) for quantification of chlorophyll content in plants. These methods using to ...
Open Access DOI:10.23937/2643-4008/1710010
Abdurrahman Kaya, MD, Mehtap Turfan, MD, Acar Yurtbasi Nuran, Ekrem Sezgin, MD and Sibel Yildiz Kaya
Article Type: Clinical Image | First Published: October 17, 2019
Streptococcus agalactiae (group B streptococcus; GBS) is gram-positive bacterium frequently colonized in pharynx, gastrointestinal and female genital tract. While the microorganism is also responsible for a wide range of infections which include sepsis and meningitis in newborn and chorioamnionitis and urinary tract infection in pregnant women, the incidence of invasive GBS disease has appeared to increase among non-pregnant adults and those with significant underlying conditions in the recent y...
Open Access DOI:10.23937/2643-4008/1710009
Peyman Ghorbani, Hamid Reza Mollaei, Seyed Alimohammad Arabzadeh and Mohammad Javad Zahedi
Article Type: Research Article | First Published: May 29, 2019
Programmed death-1 (PD-1) is major inhibitory molecule that reduces T cell activation. PD-1 and their polymorphisms have separately been shown to be associated with hepatitis B virus (HBV) infection. Therefore, we aimed to investigate the association of PD1 polymorphisms with potential of chronic hepatitis B infection in Iranian population to do a Case-Control study....
Open Access DOI:10.23937/IAMM-2017/1710008
Olga Efremenkova, Nina Gabrielyan, Irina Malanicheva, Mariya Demiankova, Tatiana Efimenko, Eugene Rogozhin, Sofiya Sharapchenko, Tatyana Krupenio, Dmitrij Davydov and Maksim Kornilov
Article Type: Research Article | First Published: May 11, 2019
The object of our research is the transient probiotic strain Bacillus subtilis 534 that is a basis of the drug Sporobacterin. The strain 534 was cultivated in submerged conditions and the obtained culture liquid (CL) was investigated for antimicrobial activity by diffusion into the agar medium method. As test objects, collection strains of bacteria and fungi were used as well as clinical isolates with different resistance to antibiotics. For preliminary chemical characterization, CL was passed t...
Open Access DOI:10.23937/iamm-2017/1710007
Maritza Fernandez, Luz Amalia Rios-Vasquez, Rogelio Ocampo-Cardona, Oscar Florez, David L Cedeno, Teresa M Garrigues, Antonio J Almeida, Ivan D Velez and Sara M Robledo
Article Type: Research Article | First Published: October 13, 2018
Cutaneous leishmaniasis (CL) is an infectious disease endemic in tropical and subtropical countries. The current drugs have severe drawbacks that restrict their use and enhance the need for better drugs. Recently, the N-iodomethyl-N,N-dimethyl-N-(6,6-diphenylhex-5-en-1-yl) ammonium iodide (C6I) was identified as a promising compound for the topical treatment of CL. The need for oral drugs with potential use to treat cutaneous, mucosal and visceral leishmaniasis, in the present work were determin...
Open Access DOI:10.23937/IAMM-2017/1710006
Emanuella Francisco Fajardo, Gabriela Roberta Braz, Mara Rosa, Tatiane Marques, Bruno Belmonte Martinelli Gomes, Thiago Mantello Bianco, Ana Karina Marques Salge, Dayana Pousa Siqueira Abrahao, Eduardo Elias Vieira de Carvalho, George Kemil Abdalla and Douglas Reis Abdalla
Article Type: Research Article | First Published: October 06, 2018
Vaginal infections and inflammations are responsible for the most demand at gynaecology, because the main complains are leucorrhea and vulvovaginitis, there is a specifically interest in cervix cancer prevention. The aim of this study is to understand the prevalence of vaginal infections cases and cervical lesions, found in women attended at health basic units from Igarapava, Sao Paulo state, Brazil....
Open Access DOI:10.23937/IAMM-2017/1710005
Pires Eduardo De Lima Sa, Morais Livia Mota, Pires Amanda De lima Sa, Matsuda Luis Otavio, Matsuda Josie Budag and Alves Angelo Roncalli Melo
Article Type: Research Article | First Published: October 05, 2018
Know the tumor stage of breast cancer and identify the immunohistochemical markers are important in the evaluation of predictive and prognostic factors, in the differential diagnosis of breast lesions and in the determination of the possible origin of metastatic neoplasms, besides helping to define the type of treatment. Cross-sectional and quantitative study of patients diagnosed with breast cancer, submitted to treatment at the Ceara Cancer Institute (ICC) mastology service from 2008 to 2012. ...
Open Access DOI:10.23937/iamm-2017/1710004
Abdelrahman M Elsawy, Hani S Faidah and Elrashdy M Redwan
Article Type: Case Report | First Published: August 08, 2018
Streptococcus salivarius (S. salivarius) is a rare cause of purulent meningitis. We report a case of meningitis due to S. salivarius in 15-years-old Sudanese boy. Diagnosis was established based on Cerebrospinal fluid (CSF) findings. The patient responded well to systemic antibiotics and recovered completely without any neurological complications after proper supportive measures. In this patient the meningitis caused by S. salivarius was thought to be spontaneous. The importance of bacteriologic...
Open Access DOI:10.23937/iamm-2017/1710003
Shih-Chao Lin, Christopher Z Lien and Chi-Chen Lin
Article Type: Short Communication | First Published: July 13, 2018
John-Cunningham virus (JCV) has been recognized as a major contributor to progressive multifocal leukoencephalopathy (PML) in humans, especially in immunodeficient patients. While the prevalence rate of PML in human populations could be up to 80%, the occurrence of tumorigenesis is around 0.07%. Thus, we investigated whether crude-oil extracts could synergistically increase the carcinogenesis along with T antigen from JC virus in vitro. Here we analysed the cell cycle distribution and cytotoxici...
Open Access DOI:10.23937/iamm-2017/1710002
Samuel Edward Kahema, Maseke Richard Mgabo, Basiliana Emidi, Geofrey Nimrod Sigalla and Debora Charles Kajeguka
Article Type: Research Article | First Published: May 16, 2018
High level of Antiretroviral Therapy adherence among HIV infected patients contributes to better treatments outcome and has additional importance in preventing the development of drug resistance. It also improves the quality of life and makes the patient live longer and healthier. The objective of the study was to determine level of adherence as well as factors influencing adherence to antiretroviral therapy among HIV infected patients in Nyamagana district, Mwanza, Tanzania....
Open Access DOI:10.23937/iamm-2017/1710001
Article Type: Review Article | First Published: November 20, 2017
Supercritical solvent impregnation is a modern technique which exploits the unique transport properties and qualities of supercritical fluids such as low viscosity, high diffusion coefficients, densities as in a liquid state and zero surface tension, for the fabrication of novel materials. The mentioned properties allow deep penetration of supercritical fluid with a dissolved bioactive substance into a solid matrix enabling even distribution of the active substance through the whole volume of th...
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