Isoproterenol and Lidocaine for Recurrent Torsades de Pointes in a 32-Year-Old Pregnant Woman
Breyanna Reachi, PharmD, Jenna Negrelli, PharmD, Abby Hickman, PharmD, MBA, BCCCP, Sarah Beesley, MD and Jeffrey Osborn, MD
Article Type: Case Report | First Published: September 19, 2019
A 15-week pregnant 32-year-old female was admitted to an outside hospital for alcohol withdrawal and developed multiple episodes of ventricular tachycardia (VT) and TdP resulting in her prompt transfer to our hospital for escalation of care. On arrival she was awake, alert, and hemodynamically stable but quickly began experiencing recurrent episodes of TdP that developed into pulseless VT despite defibrillation, magnesium and calcium administration, and chest compressions. We initiated lidocaine...
Comparison of Normal Skin and Thermal and Chemical Burn Wounds using Vibrational Optical Coherence Tomography
Frederick H Silver, Nikita Kelkar and Ruchit Shah
Article Type: Research Article | First Published: September 16, 2019
The search for methods to evaluate the extent and severity of skin lesions, such as burns and other skin disorders, has been a subject of extentive research. While suction testing, elastography and other tests can be done noninvasively on intact skin, these tests cannot be done on burns and open wounds due to the possible injury that may occur. In addition, they fail to yield comparable results obtained using destructive tests such as uniaxial tensile testing. We have developed a technique to co...
The Bone Phone: Improving Time to Pain Medication Administration in Long Bone Patients
Brian Wagers, MD, Santhi Reddi, MD, Kara Kowalzyck, MD and Jessica Kanis, MD
Article Type: Research Article | First Published: September 05, 2019
Orthopedic complaints are one of the most frequent reasons for presentations to the pediatric emergency department (PED). National metrics have defined that each child should have a pain assessment and/or pain medication administered within one hour of arrival to an emergency department. Patient surges, transfers from referring hospitals, and acuity can affect the ability of a PED to meet this metric. We queried our electronic medical record (EMR) for all patients presenting to our level 1 traum...
Enhancement of NK Cell-Mediated Lysis of Osteosarcoma Cells by Up-Regulating the NKG2D Ligands using Spironolactone and Avemar
Sellamuthu Subbanna Gounder, Thamil Selvee Ramasamy, Sharaniza Ab Rahim and Baskar Subramani
Article Type: Original Article | First Published: September 04, 2019
Natural Killer (NK) cell has the capability to immunosensitize and cell-mediated lysis of many types of cancer cells, however, most of the cancer cells are evading the NK cell-mediated lysis by down-regulating the NK cell specific ligands. In the present study, we have evaluated the comparative and synergic effect of spironolactone (SPIR) and (AVE) in enhancing the susceptibility of osteosarcoma cells (MG-63) to NK cell-mediated lysis in vitro. NK cells used in this study was characterised by th...
The 'SAFE PT' Handover: Impact on Safe Patient Handover between Shifts in the Emergency Department
Ahmed Mikky, MD, Mohamed Al Busafi, MD and Issa Al Salmi, MD, PHD
Article Type: Research Article | First Published: September 04, 2019
50 participants each were approached prior and post implementation of SAFE PT to fill descriptive questionnaires. The new SAFE PT tool was found to be clear and user friendly. It enhanced the handover process to a smooth one and was found to be systematic and highlighted the high acuity patients as well as red flags of each patient handed over. The bedside handover coupled with the prefilled written SAFE PT made it a safe process with increased patient satisfaction emphasized by the significant ...