International Journal of

Tropical DiseasesISSN: 2643-461X

Early Online

 Open Access DOI:10.23937/2643-461X/1710065

Lassa fever in Nigeria: Social and Ecological Risk Factors Exacerbating Transmission and Sustainable Management Strategies

Sylvester Chibueze Izah, Kurotimipa Frank Ovuru and Matthew Chidozie Ogwu

Article Type: Review Article | First Published: July 24, 2022

With the advent of COVID-19, infectious diseases are increasingly a cause of concern to both national and international governments as well as non-governmental organizations. This review focusses on Lassa fever incidence, prevalence, and socioecological factors influencing the spread and management of the disease in Nigeria using data mined from the Nigeria Centre for Disease Control and other public databases....

 Open Access DOI:10.23937/2643-461X/1710063

COVID-19 Vaccine Acceptance and Hesitancy: A Continental Review

Olabode Ebenezer Omotoso, Tolulope Oladimeji, John Oluwafemi Teibo and Ayomide Oluwadarasimi Adebesin

Article Type: Review Article | First Published: June 09, 2022

There are various contributory factors that decide acceptance or ensure hesitancy among the populace which includes: Age, education, gender, residence, household income, marital status, religion, information source, access to vaccine and vaccine equity, etc. Major concerns, barriers, and motivators about vaccination were highlighted....

 Open Access DOI:10.23937/2643-461X/1710064

Clinical Profile of the Diagnosis and Treatment of Human Brucellosis in Ghindae Zonal Referral Hospital, Northern Red Sea Region, Eritrea

Esayas T Mehari, MD, Dawit Kidane, Abraham Dawit Jeff, Feven T Mehari, Michael Ghebrezghabiher and Fitsum Kibreab

Article Type: Original article | First Published: June 13, 2022

The study aims to uncover the burden of brucellosis in Ghindae Zonal Referral Hospital, the therapeutic approach used at the hospital, and the outcome of treatment....

 Open Access DOI:10.23937/2643-461X/1710062

Telfairia occidentalis as a Potential Lavicide against Human Malarial Vector, Anopheles coluzzi (Diptera: Culicidae): A First Report

Nura Abubakar and Muhammad Mahe Mukhtar

Article Type: Original Article | First Published: April 28, 2022

The eco-friendly nature of plant extracts has made them become sustainable alternative vector control agents. Anopheles mosquitoes serve as the vectors for human malaria. Malaria still kills more than 600,000 individuals every year, 90% of this in sub-Saharan Africa and mostly children under five. In the present study, larvicidal activity of leaf extract of Telfairia occidentalis was evaluated against the malarial vector, Anopheles coluzzi. The adult bloodfed Anopheles mosquitoes were collected ...

 Open Access DOI:10.23937/2643-461X/1710060

Impact of a Group-Based Video and Interactive Group Session Addressing Diarrheal Disease, Helminthic and Schistosomiasis Infections, Hypertension and Diabetes on Short and Long- Term Improvement in Knowledge and Healthy Behaviors in Seroconcordant HIV-Negative Zambian Couples

Sharkey, MPH, DrPH (cand), R Parker, MSPH, KM Wall, PhD, K Malama, PhD, W Kilembe, MD, MSc, M Inambao, MD, MPH, A Tichacek, MPH, C Kwok, MPH, N Ahmed, MPH, DrPH, R Burke, MPH, RW Peeling, PhD and S Allen, MD, MPH

Article Type: Original Article | First Published: April 27, 2022

Non-communicable and neglected tropical diseases (NCD and NTD) contribute to high morbidity and mortality in Zambia. While the public health importance of NTD has long been recognized, prevalence of disease remains high. NCD are emerging as causes of morbidity and mortality. Knowledge of risk factors, diagnosis, management, and prevention of NCDs and NTDs in the general population is poor and as a result, low-cost commodities are insufficiently used. Urban couples recruited in five government he...

 Open Access DOI:10.23937/2643-461X/1710061

Isothermal Amplification-Based Detection Platforms for Pathogenic Leptospira Species in Flood and Environmental Waters

Rubigilda Paraguison-Alili, Renmar M Dela Cruz, Analiza M Balaga and Winston A Palasi

Article Type: Original Article | First Published: April 27, 2022

Detecting the occurrence of pathogenic Leptospira spp. is vital for public health implications and epidemiological studies. Different isothermal-based techniques ascribed to loop-mediated isothermal amplification (LAMP) to detect Leptospira spp. in black rats and spiked environmental waters were evaluated. In this study, modified platforms were designed to detect the lipL32 gene encoding the major outer membrane lipoprotein of Leptospira spp. Standard and direct dry isothermal technique platform...

 Open Access DOI:10.23937/2643-461X/1710059

Performance of GeneXpert in the Diagnosis of Tuberculosis in a Decentralized Area: Example of Hopital De La Paix, in Ziguinchor, Southern Senegal from 2016 to 2018

Kalilou Diallo, Ansoumana Diatta, Bruce Shinga Wembulua, Awa Camara, Habibou Sarr, Mame Ngone Coly, Alassane Diatta and Noel Magloire Manga

Article Type: Research Article | First Published: March 17, 2022

The Xpert MTB/RIF test is one of the innovative responses to the challenges of early diagnosis of tuberculosis and rifampicin resistance. Three years after the arrival of GeneXpert at La Paix hospital, we carried out this study in order to assess its contribution to the diagnostic process. This cross-sectional, descriptive and analytical study focused on suspected tuberculosis patients whose pathological products were analyzed at the unit of microbiology of La Paix hospital of Ziguinchor, Senega...

 Open Access DOI:10.23937/2643-461X/1710058

Antimicrobial Resistance Patterns of Pseudomonas aeruginosa in a Vietnamese Tertiary Care Hospital

Thi Ha Vo, PhD, Pharm, Quang Hien Bui, BSc, Pharm, Hoang Hai Nguyen, PhD, MD and Hong Tham Pham, BSc, Pharm

Article Type: Original Article | First Published: March 17, 2022

Vietnam is one of the countries at high alert of antibiotic resistance. This study aimed to evaluate the antimicrobial susceptibility of P. aeruginosa isolates collected from a Vietnamese hospital in 2019. A retrospective review was conducted of all reports of P. aeruginosa isolates from the records of the laboratory of Nhan Dan Gia Dinh Hospital between January 01 2019 to December 31 2019. Of 224 samples, the most common infection from which P. aeruginosa was isolated was pneumonia in hospitali...

 Open Access DOI:10.23937/2643-461X/1710057

Understanding the Systemic Effects of COVID-19: Possible Clues to Potential Therapeutic Approaches

Oritoke M Aluko, Saheed A Lawal, Celestine S Reuben, Sikirullai O Jeje and Omamuyovwi M Ijomone

Article Type: Review Article | First Published: February 18, 2022

The novel coronavirus disease (COVID-19) is an infectious disease caused by the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It is an acute respiratory disease that causes life-threatening symptoms. This virus directly or indirectly affects the various systems of the body. In the respiratory system, it causes pulmonary edema, impaired oxygen diffusing capacity, difficulty in breathing, etc. In the nervous system, it causes encephalitis, thrombo-embolitic stroke, Guillan-Barr...

 Open Access DOI:10.23937/2643-461X/1710056

Analysis of IgG Responses to P. falciparum Antigens MSP1, MSP4-20 and MSP4-40 during Severe Malaria in Dakar, Senegal

Bruce Shinga Wembulua, Kalilou Diallo, Folly Mawulolo Gaba, Babacar Mbengue and Louise Fortes

Article Type: Original Article | First Published: February 07, 2022

Antibodies to merozoite surface antigens (MSPs), the primary targets of malaria vaccine research, are associated with low malaria morbidity. However, few studies have looked at the implications of their variations on the evolution of clinical-biological forms of severe malaria. This cross-sectional, prospective, and analytical study evaluates by ELISA the IgG responses directed against the antigens MSP1, MSP4-20 and MSP4-40 of P. falciparum during severe malaria in patients hospitalized in the i...

Volume 5
Issue 1