ClinMed International Library

The ClinMed International Library is a repository and an open access publisher for medical research that covers a wide range of areas in Clinical Medicine. ClinMed serves as a global platform for medical practitioners and research scholars to foster their learning and professional acumen through an extensive portfolio of research articles and publications that can be accessed without any restrictions.

Dedicated to clinical medical research, we now publish over 70 quality peer-reviewed journals making all the articles freely accessible. The manuscripts submitted to ClinMed will be processed through standard parameters and international peer review systems. This has enabled us to establish new milestones in the global research arena in terms of cogency and integrity, and to disseminate highly credible and accredited research content for researchers, scholars, and practitioners across the globe.

We ensure that all researchers and authors publishing their papers with us retain copyrights, licensed under Creative Commons Attribution License that permits the unrestricted use and re-use of the content with proper citation.

COVID-19 related research

Further Evidence of a Possible Correlation between the Severity of Covid-19 and BCG Immunization
Serge Dolgikh
Full article:90464112 | HTML:90464113 | DOI:10.23937/2474-3658/1510120
Strategies of the World Health Organization in the Covid 19 Outbreak
Emel Yürük Bal, (RN) MSc and Şenay Çetinkaya, PhD
Full article:90464112 | HTML:90464113 | DOI:10.23937/2474-3658/1510118
COVID-19 Threat to Major Global Urban Centers
Jean-dAmour K Twibanire
Full article:90464112 | HTML:90464113 | DOI:10.23937/2474-3658/1510116
Covid-19 Epidemic in Italy: Lesson Learning
Giangaspero M, DVM, MSc, PhD
Full article:90464112 | HTML:90464113 | DOI:10.23937/2469-5793/1510119
Modified Non-Invasive Computational Methods of HIV Drug Combinations for Treatment of Coronavirus Disease-19 (COVID-19)
Tamer Ezzat Youssef and Youssef Tamer Moustafa
Full article:90464112 | HTML:90464113 | DOI:10.23937/2469-567X/1510061
Epidemiology and Diffusion of Some Relevant Virus: Latitude, Air Pollutants and Humidity Role, Hypothesis of Work: Covid-19 Effect on the Air Pollution in Some World Region: What Implications?
Luisetto M, Ahmed Yesvi Rafa, Khaled Edbey, Ghulam Rasool Mashori, Farhan Ahmad and Oleg Yurevich Latyshev
Full article:90464112 | HTML:90464113 | DOI:10.23937/2572-4061.1510031
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Articles Search by   Keyword   |   Journal title   |   Author name   |   DOI

 Open Access DOI:10.23937/2377-3634/1410020

Torpid Diabetic Wound Healing: Evidence on the Role of Epigenetic Forces

Jorge Berlanga-Acosta, Yssel Mendoza-Mari, Maday Fernandez-Mayola, Ariana GarciaOjalvo, Calixto Valdes-Perez, William Savigne-Gutierrez, Daniel Reynaldo-Concepcion, Ileydis Iglesias-Marichal, Angel Abreu-Cruz, Celso Suarez-Lescay, Ana Mir-Benitez, Natacha Sancho-Soutelo and Luis Herrera-Martinez

Article Type: Research Article | First Published: January 29, 2015

The increasing number of diabetes patients represents a health challenge due to disease-related, end-organs complications. Hyperglycemia is considered the proximal trigger of an intricate cascade of molecular processes that progressively deteriorate tissues and organs, leading to the onset of clinical complications. Lower extremity ulcerations and their ensued refractoriness to heal can potentially result in amputation and disability and remain the second most feared diabetic complication. We ha...

 Open Access DOI:10.23937/2377-4630/2/1/1020

Fontan Physiology: Anaesthetic Implications for Non-Cardiac Surgery: A Case Report

Harikrishnan Kothandan, Lim Michelle Leanne and Shital Kumar Sharad Shah

Article Type: Case Report | First Published: February 06, 2015

Patients with congenital heart diseases are a growing population and noncardiac surgeries will become an important health care issue. Modification of surgical techniques and medical advances has improved the survival of patients with complex congenital cardiac abnormalities, resulting in more adult patients with fontan physiology presenting for non-cardiac surgery. The older fontan patient is at particular risk of thromboembolism, arrhythmias, progressive ventricular dysfunction, protein losing ...

 Open Access DOI:10.23937/2378-3419/2/1/1012

Phase I Clinical Study of Survivin-Derived Peptide Vaccine for Patients with Advanced Gastrointestinal Cancers

Fukino Satomi, Hiroaki Shima, Toru Mizuguchi, Toshihiko Torigoe, Goro Kutomi, Yasutoshi Kimura, Yoshihiko Hirohashi, Yasuaki Tamura, Tomohide Tsukahara, Takayuki Kanaseki, Akari Takahashi, Hiroko Asanuma, Yoichi M. Ito, Hiroshi Hayashi, Osamu Sugita, Noriyuki Sato and Koichi Hirata

Article Type: Original Article | First Published: February 04, 2015

Survivin is a member of the Inhibitor of Apoptosis Protein (IAP) family. It is expressed in fetal tissues but not in normal adult tissues. Since Survivin is over expressed in various types of tumor tissues as well as tumor cell lines, it is considered to be suitable as a target antigen for cancer vaccine therapy. We identified an HLA-A24-restricted antigenic peptide, SVN-2B (AYACNTSTL), derived from a splicing variant of Survivin-2B. In the present study, we carried out a phase I clinical study ...

 Open Access DOI:10.23937/2378-2951/1410020

Relationship between Insulin Levels and Coronary Atherosclerosis in Newly Diagnosed Diabetes Mellitus and Impaired Glucose Tolerance

Naohiko Nemoto, Rintarou Nakajima, Kennji Ymazaki, Makoto Utsunomiya, Masaki Hori, Shingo Ito, Itaru Yokouchi, Masamichi Wada, Masanori Shiba, Hisao Hara, Hidehiko Hara, Takuro Takagi, Kaoru Sugi and Masato Nakamura

Article Type: Review Article | First Published: February 06, 2015

Background: While some therapies implemented for newly diagnosed Diabetes Mellitus (DM) or impaired Glucose Tolerance (IGT) are effective in preventing cardiovascular events, investigations of coronary plaque in patients with newly diagnosed DM or IGT are lacking. Methods: We evaluated 96 patients with acute coronary syndrome. The External Elastic Membrane (EEM), Lumen Cross-Sectional Area (CSA), plaque CSA, and plaque burden in the Left Anterior Descending (LAD) artery proximal to the lesion, d...

 Open Access DOI:10.23937/2378-2951/1410019

Physical Examination of the Cardiovascular System

John P. Higgins

Article Type: Review Article | First Published: January 27, 2015

The physical examination, while frequently not performed well, is critical to the diagnosis and management of cardiovascular disorders. This paper describes a basic cardiovascular physical examination and explains findings, with the goal of improving skills in this area....

 Open Access DOI:10.23937/2377-4630/2/1/1019

Proposing a Novel Concept to Evaluate Safety of Supraglottic Devices Regarding Seal Pressure during Laparoscopic Surgery

Jose M. Belena, Monica Nunez and Alfonso Vidal

Article Type: Opinion | First Published: January 23, 2015

It is a fact that Supraglottic Airway Devices (SAD) are currently present at many clinical scenarios in anesthesia and they are also a good alternative to endotracheal intubation in some routine anesthetic procedures. Nowadays, laparoscopy is one of the most common and widely established surgical techniques. This procedures increase airway pressure due to the peritoneal insufflation and consequently the risk of regurgitation and aspiration. Over the last two decades, many studies have establishe...

 Open Access DOI:10.23937/2469-5696/1410005

A Case of Localized Neuroblastoma in Caffey Disease, with Early and Uncommon Progression

Manuela Pagano, Chiara Galletto, Maurizio Bianchi and Franca Fagioli

Article Type: Case Report | First Published: January 21, 2015

Background: Caffey disease is a rare syndrome caused by mutation in the alpha-1 collagen type I gene, not described in literature as a predisposing condition to cancer development. Observation: We report a case of a 6-years-old female diagnosed with Caffey disease that developed a localized neuroblastoma. The patient had a poor clinical and radiological response with unusual disease dissemination and progression until death. Conclusion: The case is a rare example of rapid progression of localize...

 Open Access DOI:10.23937/2469-5696/1410004

Diverse Genotype Presentation of the Saudi-Type Poly A Signal Mutation (αTsaudiα) in the Population of Bahrain

Nabeel Al Moamen, Fawzia Mahdi, Ahmed Thabet, Rugaya Abbas, Ebtihal Salman and Ahmed Al Alawi

Article Type: Letter to Editor | First Published: January 15, 2015

A total of 1187 patients with α-thalassemia phenotype presentation have been recruited for this investigation. Preliminary diagnosis of α-thalassemia was based on low hematological indices (MCV and MCH) of the red blood cells and/or persistently low hemoglobin levels, along with low or normal levels of HbA2 and absence of iron deficiency. Th molecular diagnosis of α-thalassemia was established by using a commercially available α-thalassemia strip assay (α-Globin StripAss...

 Open Access DOI:10.23937/2378-346X/1410010

Macular Multifocal Granular Hyperfluorescence on Fluorescein Angiography

Taiichi Hikichi

Article Type: Research Article | First Published: January 30, 2015

Purpose: To investigate the causes of multifocal granular hyperfluorescence at the macula on Fluorescein Angiography (FA) in Japanese patients. Methods: I retrospectively studied 1,457 consecutive Japanese patients (1,457 eyes) who underwent digital simultaneous FA and indocyanine green angiography (ICGA). Results: One hundred forty-seven of the 1,457 eyes had multifocal granular hyperfluorescence on FA images. Of the 147 eyes, 94 (64%) eyes had polypoidal choroidal vasculopathy (PCV); 25 (17%) ...

 Open Access DOI:10.23937/2378-346X/1410009

Optic Disk Size Assessment Techniques: Photo Essay

Sourabh Arora, Helen Chung and Karim Damji

Article Type: Case Report | First Published: January 25, 2015

Measuring optic disc size is an essential part of the optic nerve head for evaluation for glaucoma. Large discs that appearing to have large cups may in fact be physiologic because of normal neuroretinal rim area. Small discs may appear to have a normal cup to disc ratio, but have decreased neuroretinal rim area in association with glaucoma. We illustrate relevance of these points with respect to glaucoma diagnosis in two case examples. We then present clinically relevant techniques to assess di...

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