Journal of Otolaryngology and Rhinology is an international, open access, peer-reviewed journal that publishes a wide variety of information on all aspects of head and neck medicine. The main objective of the journal is to set a forum for publication, education, and exchange of opinions globally. The Journal provides a podium for all clinicians, surgeons and health professionals to contribute their findings and help raise awareness among the community in various aspects of otology, rhinology, and laryngology. We aim to publish the highest quality clinical content via open access platform providing the readers free, immediate and unlimited access.
Journal of Otolaryngology and Rhinology is an open journal which provides research updates on Otology, Congenital deformities of the ear and temporal bone, Disorders of equilibrium, Neurological and Vascular causes of vertigo, Hearing loss, Facial Paralysis, Cochlear implantation in adults and children; Devices including bone anchored hearing aids and middle ear implants, Tinnitus, Ear trauma, Chronic suppurative otitis media including its intracranial complications, Neck masses in infants and children, Airway disorders in childhood, Congenital deformities of the ear and temporal bone, Basic sciences of rhinology, Congenital nasal abnormalities, Nose and sinus infections, Nose and sinus inflammation excluding infection, Nasal polyps, Foreign bodies, Epistaxis, Nasal trauma and deformity, Nasal and paranasal sinus tumours, Adenoidal and tonsillar pathology, Congenital deformities of the larynx, Head and neck cancer, Airway disorders, Voice disorders, Pharyngeal and oesophageal disorders, Cervical lymphadenopathy, Sleep apnoea, Adenoidal and tonsillar pathology, Rhinology, Basic sciences, Congenital abnormalities, Diseases of the oesophagus, Benign Oesophageal and Related Disorders in Childhood, Oesophageal Neoplasia etc. Original Article, Reviews, Mini-Reviews, Short Communications, Case Reports, Clinical Image, Perspectives/Opinions, Letters, Short Note, and Commentaries are accepted for publication. All articles published in the journal are subject to a rigorous peer review process. It encourages authors to publish their results in detail to disseminate the updated research findings.
Articles Search by Keyword | Journal title | Author name | DOI
Open Access DOI:10.23937/2572-4193.1510070
Article Type: Case Report | First Published: December 05, 2019
Epidermal cyst of the bony external auditory canal in adults is rare. Only nine cases are reported in the literature. They occasionally tend to develop into a malignancy. A 35-years-old female presented with complaints of decreased hearing and fullness at the left ear. The severity of these symptoms increased gradually for 6 months. On physical examination, the left otoscopy showed a mass that was completely occluding the canal; the tympanic membrane was not visualized. The property of this mass...
Open Access DOI:10.23937/2572-4193.1510068
Saad M Alshammari, MD and Nada A Alshaikh, MD
Article Type: Research Article | First Published: October 21, 2019
Endoscopic sinus surgery (ESS) gained growing popularity with indications expanding beyond rhinosinusitis. Preoperative high-resolution computed tomography (CT) scan is essential in providing the surgical map for surgeons. In addition of being a diagnostic imaging technique, it gives valuable information about origin, nature and extension of the pathology to adjacent structures. Therefore, preoperative review of para-nasal sinuses (PNS) CT scan is crucial in order to perform successful and compl...
Open Access DOI:10.23937/2572-4193.1510069
Ryan Marshall, MD, Gobind Gill, MD, Mohamad Babi, MD, Kirk Withrow, MD and Do-Yeon Cho, MD
Article Type: Research Article | First Published: November 04, 2019
The purpose of our study is to prove open repair (OR) for Zenker's diverticulum can result in similar lengths of stay in the hospital, and similar convalescent periods when compared to endoscopic repair (ER). Retrospective chart review was performed between 2013-2018 for those patients who had surgical repair of Zenker's diverticulum by two surgeons. After discussing all risks, benefits, and alternatives, patient made a decision whether to have ER vs OR of Zenker's diverticulum. These findings s...
Open Access DOI:10.23937/2572-4193.1510067
Anna Frants, MD, Marissa Lafer, MD, Cheng Z Liu, MD and Judy W Lee, MD
Article Type: Case Report | First Published: October 14, 2019
Aneurysmal fibrous histiocytoma (AFH), also known as aneurysmal dermatofibroma, is a rare variant of the more common and benign dermatofibroma (fibrous histiocytoma). AFHs account for approximately 2% of all cutaneous fibrous histiocytomas, and have been reported to occur most often on the extremities of young to middle aged adults, with a slight female predominance. The mass was excised en bloc using an open rhinoplasty approach. Once the nasal skin-SMAS envelope was elevated, a lobular, cystic...
Open Access DOI:10.23937/2572-4193.1510066
Nikolaus Hjelm, MD, Peter Ciolek, MD, Ryan Heffelfinger, MD and Howard Krein MD, PhD
Article Type: Case Report | First Published: October 07, 2019
As one ages, the structure of the nose undergoes a number of changes, leading to alterations in form and function. Patients with no previous history of nasal issues may present with age-related nasal obstruction later in life. Tip ptosis is a well-recognized etiology of nasal obstruction in the aging patient. The pathogenesis is believed to be due to weakening of several of the tip support mechanisms. Of primary importance, there is age-related degradation of the fibrous union at the cephalic ed...
Open Access DOI:10.23937/2572-4193.1510065
Erkan YILDIZ, Sahin ULU and Orhan Kemal KAHVECI
Article Type: Research Article | First Published: August 26, 2019
Nasal septal perforation is the most common complication in the long term after septoplasty. Nasal septal perforation is the partial opening of the wall between both nasal cavities. In this study, we will evaluate the causes of septal perforation after septoplasty. 400 patients aged between 18 and 50 years who underwent septoplasty operation in Afyonkarahisar Şuhut State Hospital between 2016- 2019 were evaluated retrospectively. These patients were divided into groups with and without perforat...
Open Access DOI:10.23937/2572-4193.1510064
Manola M, Moscillo L, De Luca E, Lalinga AV and Possidente L
Article Type: Case Report and Literature Review | First Published: August 26, 2019
Salivary gland tumours constitute 3% of all head and neck neoplasms. Pleomorphic adenomas arising in the maxilla are extremely rare, with only few cases reported to date. Radiographically and clinically, these lesions have the appearance of osteolytic processes or odontogenic cysts and the diagnosis represents a challenge. The surgical treatment of intraosseous glandular neoplasms is debated because of the few cases reported in literature. The Authors describe a rare case of intraosseous pleomor...
Open Access DOI:10.23937/2572-4193.1510063
Bahareh Bakhshaie Philipsen
Article Type: Review Article | First Published: August 21, 2019
Difficulty swallowing is called dysphagia. There is a wide range of potential causes of dysphagia. Because there are many reasons why dysphagia can occur, treatment depends on the underlying cause. Thorough examination is important, and implementation of a treatment strategy should be based on evaluation by a multidisciplinary team. In this article, we will describe the mechanism of swallowing, the pathophysiology of swallowing dysfunction and different causes of dysphagia, along with signs and ...
Open Access DOI:10.23937/2572-4193.1510062
Graham Derek Unis, MS, BA, Basit A Jawad, MD, Ashwin Ananth, MD and Ryan Winters, MD
Article Type: Review Article | First Published: August 12, 2019
We present a case of a 72-year-old gentleman with an extruding internal carotid artery aneurysm coil through the Fossa of Rosenmuller. The patient was stable post-operatively and remained complication and progression free 8 months later at time of writing. Other reports involving pseudoaneurysms were found in the literature although no coil erosions in true aneurysms have been described. Conservative therapy with controlled amputation of the extruding filament in the operative room has served as...
Open Access DOI:10.23937/2572-4193.1510061
Gilberto Eduardo Marrugo Pardo, Carlos Julian Adarme Gomez and Alejandra Oliveros Vargas
Article Type: Research Article | First Published: August 07, 2019
Septic thrombosis of the lateral sinus is a rare complication of otitis media; currently, it hasn't been found a case report of septic thrombosis of the lateral sinus in the medical literature of Colombia and, in addition to this, there is no consensus in the management of this pathology. Hence the importance of the present case, which is a 3-year-old male patient, who presented a clinical picture of 7 days of evolution characterized by right otalgia and fever, which after the administration of ...
Open Access DOI:10.23937/2572-4193.1510060
Nannan Zhang, Mintao Zhong, Delong Liu, Cuiping Se, Wei Song and Qingfeng Zhang
Article Type: Research Article | First Published: June 10, 2019
Current surgical treatment for chronic rhinosinusitis and nasal polyps is functional endoscopic sinus surgery (FESS). Coblation-assisted Functional endoscopic sinus surgery (CAFESS) will probably replace of FESS with more effective result. Our aim was to explore the safety and efficacy of CAFESS for the patients with chronic rhinosinusitis and nasal polyps comparing to traditional FESS firstly by observing clinical data....
Open Access DOI:10.23937/2572-4193.1510059
Aman, Jagat Singh, Ashiya Goel, Chandni Sharma, Vikasdeep Gupta and Swati
Article Type: Research Article | First Published: April 27, 2019
Otitis media with effusion (OME) is an important and common condition in paediatric age group. It is the leading cause of hearing loss and a social morbidity in children which has long-term consequences for speech and language development. Adenoid hypertrophy is an important etiological factor in the causation of OME. Recurrent attacks of rhinitis, sinusitis and chronic tonsillitis may cause chronic adenoid infection and hyperplasia. Allergy of the upper respiratory tract may also contribute to ...
Open Access DOI:10.23937/2572-4193.1510058
Muhd Faiz Bin Zulkifli and Lokman Bin Saim
Article Type: Case Report | First Published: April 20, 2019
A 23-year-old female presented with progressive left sided facial asymmetry for 4 years and progressive hearing loss in the left ear for 2 years. She had normal left tympanic membrane and complete left lower motor neuron facial nerve palsy. High resolution computed tomography (HRCT) and magnetic resonance imaging (MRI) temporal bone showed extensive bony destruction, petrous apex and soft tissue lesion. Patient then proceed with transmastoid translabyrinthine approach. Diagnosis of cholesteatoma...
Open Access DOI:10.23937/2572-4193.1510056
Lewis William Murray
Article Type: RESEARCH ARTICLE | First Published: March 08, 2019
Both epistaxis and mental health disorders are common conditions encountered in medical practice and whilst there have been investigations into individual psychiatric conditions and epistaxis, to date no overview has been published of these conditions. This review aims to summarise the various aetiologies and their managements in the setting of epistaxis. A literature review was conducted using PubMed, Medline Ovid, and the Cochrane library using the terms epistaxis, mental health, psychiatric, ...
Open Access DOI:10.23937/2572-4193.1510055
Masih Ahmed, MD, Sarah Ellison, MD and Kathryn S Moffett, MD
Article Type: CASE REPORT | First Published: February 27, 2019
A 10-year-old male was admitted to our hospital after worsening right-sided neck lymphadenitis and fever of 39.8 ℃ (103.6 ℉) of 7 days duration. He had been admitted to an outside facility and treated for 3 days with intravenous (IV) ampicillin/sulbactam and clindamycin, where a computed tomography (CT) revealed right sided lymphadenitis with no abscess formation. Blood and throat cultures showed no growth. Upon admission to our hospital, he had right neck swelling with tenderness and erythe...
Open Access DOI:10.23937/2572-4193.1510054
Fatima Betul Basturk, PhD, Dilek Turkaydin, PhD, Sertac Aktop, PhD and Hesna Sazak Ovecoglu, PhD
Article Type: Case Report | First Published: February 07, 2019
Dental practitioners frequently encounter with instrument fracture during root canal treatment. However, these fractures generally occur inside the root canals. It is not usual that high speed rotary instruments snap and go further to important anatomical landmarks. In our case report, a high-speed Gates-Glidden drill perforated the root and was introduced into the left maxillary sinus during a routine root canal treatment. The dental and surgical management of the case are described and the pos...
Open Access DOI:10.23937/2572-4193.1510053
Jason F Ohlstein, Thomas S Edwards, Charles A Riley, Joseph F Buell and Paul L Friedlander
Article Type: Original Article | First Published: Janaury 21, 2019
Retrospective chart review of 100 consecutive patients presenting from each of two tertiary referral centers in inner city New Orleans, Louisiana located in the same zip code serving the local community, with a new diagnosis of squamous cell carcinoma of the head and neck between 2011 and 2014.The data from 187 patients were analyzed for delay at presentation and subsequent provider delay. Statistical analysis was performed to evaluate the effect of race, insurance status, and patient navigation...
Open Access DOI:10.23937/2572-4193.1510052
Muhd Faiz Bin Zulkifli Nor Rahimah Binti Aini and Siti Sabzah Mohd Hashim
Article Type: Case Report | First Published: January 03, 2019
Congenital giant cervical lymphatic malformation are rare tumors. Recent advances in prenatal diagnosis and delivery by ex utero intrapartum treatment (EXIT) have improved prenatal outcome. An otherwise healthy 35-year-old woman, gravida 5, para 4, was referred to our institution at 25 weeks' gestation with a diagnosis large neck mass in the fetus. Prenatal ultrasound and magnetic resonance imaging (MRI) findings suggested airway obstruction in the fetus. The EXIT procedure attempt to deliver th...
Open Access DOI:10.23937/2572-4193.1510051
Omoregie J Idugboe, Babatope A Kolawole and Ebidisemene L Totyen
Article Type: Research Article | First Published: November 03, 2018
Among the most common chronic disorders of modern time, diabetes mellitus remains unique because of its multifactorial ramifications. Apart from the well-described association between congenital deafness and maternally inherited type of diabetes mellitus, the relationship between type 2 diabetes and hearing loss has been the subject of debate since Jordao reported a case of hearing loss with incipient diabetes coma almost 150 years ago. Documentation of this relationship among adult diabetics in...
Open Access DOI:10.23937/2572-4193.1510050
Meichan Zhu, Guangyao He, Songhua Tan and Anzhou Tang
Article Type: Case Report | First Published: October 27, 2018
Squamous cell carcinoma in pinna and external auditory canal is rare and aggressive variant of cell carcinoma. We report the case of squamous cell carcinoma in pinna and external auditory canal. The case is presented, along with a brief literature review concerning squamous cell carcinoma in pinna and external auditory canal. The patient experienced locally invasive squamous cell carcinoma in his right pinna and external canal with invasive of the right parotid, temporomandibular joint, external...
Open Access DOI:10.23937/2572-4193.1510049
Francisco Andre Escamilla Islas, Jose Luis Treviño Gonzalez and Jose Martin Martinez Camarillo
Article Type: Review Article | First Published: October 17, 2018
The antrochoanal polyp (ACP) is a unilateral, solitary, pear shaped mass with a cystic stalk, differing from the inflammatory polyps in the formation of a constricted sac, half in the maxillary antrum and the other half in the nose, extruding in a variable extent to the nasopharynx. The ACP has a clinic diagnosis, with image studies as the CT scan and the MRI for the differential diagnosis. By microscopy ACP lacks minor mucoserous glands and a well-developed eosinophilic inflammatory infiltrate,...
Open Access DOI:10.23937/2572-4193.1510048
Yang Liu, Yitung Chen, Woosoon Yim and Robert C Wang
Article Type: RESEARCH ARTICLE | First Published: September 24, 2018
The prevalence of obstructive sleep apnea (OSA) has been growing over the last few decades, but the treatment outcome differs from person to person. Interest in patient-specific modeling has increased substantially. The availability of detailed clinical data together with efficient numerical methods has now made the fluid-structure interaction modeling feasible. The current study uses 3-D two-way fluid-structure interaction to provide simulation results of the sleep apnea symptom in a female pat...
Open Access DOI:10.23937/2572-4193.1510047
Marrugo Pardo Gilberto, Romero Moreno Luis Felipe and Munoz Becerra Daniel Edilberto
Article Type: Case Report | First Published: August 25, 2018
Idiopathic bilateral facial palsy is a rare entity with an incidence range between 0.2% and 0.3%. Granulomatosis with polyangiitis disease, Guillain Barre Syndrome, Systemic Lupus Erythematosus and infectious diseases such as neurosyphilis, parotiditis or borrelliosis are the main secondary causes of peripheral bilateral facial palsy....
Open Access DOI:10.23937/2572-4193.1510046
Salil Sood and Deepak Gupta
Article Type: Research Article | First Published: July 13, 2018
Over the years the importance of middle turbinate has increased with the wider use of nasal endoscopes in the management of the sino nasal diseases. Lateralization of the middle turbinate may cause scarring & adhesions which may affect the results of the surgery. We have been using a simple technique of placing a transeptal suture to stabilise the middle turbinate and prevent adhesions between middle turbinate and the lateral wall of the nose. We have used this technique in prospective study, wh...
Open Access DOI:10.23937/2572-4193.1510045
Sumana CV and Suhel Hasan
Article Type: Case Report | First Published: July 12, 2018
Silent sinus syndrome is a rare clinical entity affecting the maxillary sinus, causing progressive enophthalmos and hypoglobus resulting from retraction of maxillary sinus walls with increase in the orbital volume. We report a case of a 29-year-old male who presented with painless enophthalmos, without any disturbances in vision or ocular movements, with no history of sinusitis in the past....
Open Access DOI:10.23937/2572-4193.1510044
Saliha KARATAY and Berrire KURT
Article Type: Clinical Image | First Published: June 16, 2018
A 56-year-old female patient with osteoarthritis of the knee is presented pustules in her ear corresponding to knee and gastrointestinal auricular points. When she came to our clinic, her primary complaint was knee and hip pain. She had a history of generalized osteoarthritis for eight years. She had tried paracetamol, NSAIDs and hyaluronic acid injections as well physical therapy. Her pain was assessed at 8 by visual analog scale (VAS). We decided to treat her with acupuncture....
Open Access DOI:10.23937/2572-4193.1510043
Scott Mitchell, Matthew JV Holmes and Nicholas Turner
Article Type: Research Article | First Published: June 08, 2018
Down syndrome is one of the most common genetic conditions affecting approximately 1 in every 1000 live births. There are a multitude of potential clinical manifestations associated with this condition including dysmorphic features, organic disorders such as congenital cardiac defects, gastrointestinal defects, ocular abnormalities, celiac disease and endocrine disorders along with haemato-oncological, immunological and disorders affecting the ears, nose and throat....
Open Access DOI:10.23937/2572-4193.1510042
Article Type: Review Article | First Published: June 07, 2018
Since it was approved in 2003 by the FDA for the therapy of adult and adolescent moderate-severe persistent uncontrolled allergic asthma, the studies on asthma patients have demonstrated that omalizumab has an encouraging safety report, regardless of the allergic sensitization type. Omalizumab was later tried in the therapy of other Th2-type allergic disorders e.g. allergic asthma. Omalizumab hinders IgE effector functions by preventing IgE joining to high-affinity IgE receptors (FcεRI) on effe...
Open Access DOI:10.23937/2572-4193.1510041
Ozan Gokdogan, Hacer Baran, TolgahanCatli and Recep Karamert
Article Type: Case Report | First Published: May 30, 2018
Penetrating injuries usually affects non-dressed parts of body. Most of them treated by patient itself without any intervention. But some of them must be examined and treated by a specialist such as major injuries, minor injuries affecting the important structures and curved foreign bodies. Curved injuries can be made by a curved wire or fishhooks. Fishhooks take an important part of this injuries because of mechanism used in distal part of fishhooks....
Open Access DOI:10.23937/2572-4193.1510040
Alfonso Reyes Escobedo, Karla M Santos Santillana and Jose Luis Trevino Gonzalez
Article Type: Review Article | First Published: May 28, 2018
Recurrent respiratory papillomatosis (RRP) is a benign tumor of the respiratory tract caused by the human papillomavirus (HPV). It is considered as a manageable rather than a curable disease because of its high recurrence rates and its unpredictable clinical course. The unique molecular characteristics of the virus, induces cellular proliferation causing airway obstruction....
Open Access DOI:10.23937/2572-4193.1510039
Ahmad Elkhatib, Paul Wakely Jr, Luciano M Prevedello, Ralph Abi Hachem, Andre Beer-Furlan, Daniel M Prevedello and Ricardo Carrau
Article Type: Case Report | First Published: May 25, 2018
Report of the first case of chondroblastoma involving the sinonasal cavity and ventral skull base, offering a description of the puzzling diagnostic process followed by its management. We describe the main radiologic and histologic characteristics of chondroblastoma and compare them to those of frequently mistaken differential diagnoses....
Open Access DOI:10.23937/2572-4193.1510038
Moustafa W Mourad, Sami P Moubayed and Edward Shin
Article Type: Case Report | First Published: May 24, 2018
Giant cell angiofibroma (GCA) was first described in 1995, as a previously unrecognized soft tissue tumor of the orbit. Since that time, rare extraorbital head and neck manifestations of GCA have been documented. To the best of our knowledge, we present the fourth documented case of GCA of the buccal cavity, constituting the largest dominant site of occurrence in the extraorbital head and neck....
Open Access DOI:10.23937/2572-4193.1510037
Mahir Khuri, Riad Khniefes, Noam Yehudai and Rabia Shihada
Article Type: Case Report | First Published: May 17, 2018
Lymphoma of the nasal cavity represent only 0.2-2% of head and neck lymphomas. Treatment is medical with an overall low 5-years survival between 40% and 59%. There are high rates of relapse as well as radiotherapy and chemotherapy resistance. We present a 44-year-old male, who was admitted to our department due to chronic sinonasal infection, complicated by a large septal perforation and nasal tissue necrosis, which developed over several months following an elective septoplasty surgery performe...
Open Access DOI:10.23937/2572-4193.1510036
Mark Gelpi, Emily N Ahadizadeh, Brian D'Anzaa and Kenneth Rodriguez
Article Type: Case Report | First Published: April 30, 2018
Cystic fibrosis (CF) is a multisystem disease that can have significant sinonasal manifestations. Viscous secretions are one of several factors in CF that result in chronic sinonasal pathology, such as sinusitis, polyposis, congestion, and obstructive crusting. Persistent discomfort and nasal manifestations of this disease significantly affect quality of life....
Open Access DOI:10.23937/2572-4193.1510035
Jeremy Goh Chin Guan and Yeo Seng Beng
Article Type: Research Article | First Published: April 28, 2018
Otosclerosis is a disease of the temporal bone that affects the inner and middle ear. It is characterized by a pathological pleomorphic replacement of normal bone with spongiotic or sclerotic bone. Otosclerosis has traditionally been presumptively diagnosed by characteristic clinical findings on medical history, physical examination and audiology testing....
Open Access DOI:10.23937/2572-4193.1510034
RA Fearnley, S Badiger, CA Oti and I Ahmad
Article Type: Research Article | First Published: January 20, 2018
Accurate localisation of the cricoid cartilage is a key step in the successful application of cricoid pressure during rapid sequence induction. Poorly localised pressure is unlikely to confer any protective benefit to our patients and may have deleterious effects on laryngoscopy. We postulated that the use of ultrasound would greatly improve the accuracy of cricoid cartilage localisation prior to the application of cricoid pressure....
Open Access DOI:10.23937/2572-4193.1510033
Vidur Bhalla, Naweed Chowdhury, Thomas Muelleman, Sameer Alvi, Chelsea Hamill, Roukoz Chamoun and D David Beahm
Article Type: Case Report | First Published: November 29, 2017
Sinonasal Teratocarcinosarcomas (SNTCS) are rare tumors of the anterior skull base that are typically diagnosed in the fifth decade of life, with only 5 reported cases in children. Treatment typically involves surgical resection and radiotherapy....
Open Access DOI:10.23937/2572-4193.1510032
Bottini G, Brandtner C,Rasp G and Gaggl A
Article Type: Case Report | First Published: November 15, 2017
Supraglottic laryngectomy for laryngeal cancer aims to remove cancer of the larynx whilst preserving its functions of airway protection, breathing and voice production. A well-known long-term complication of this procedure is aspiration....
Open Access DOI:10.23937/2572-4193.1510031
Vidur Bhalla, Thomas Muelleman, Chelsea S Hamill, D David Beahm, Hesham M Soliman, Roukoz B Chamoun and Kathy Newell
Article Type: Case Report | First Published: May 31, 2017
Pediatric brain tumors are the leading cause of cancer in children. While children more likely present with craniopharyngiomas, germinomas or optic gliomas, synchronous intracranial lesions are highly uncommon. Here, we describe the case of a 10-year-old female who presented with central Diabetes Insipidus (DI)....
Open Access DOI:10.23937/2572-4193.1510030
Thilaga Rajendran, Velayutham Kamaru Ambu and Azila Alias
Article Type: Case Report | First Published: March 30, 2017
Laryngeal cancer is rising in incidence among elderly men with history of smoking. Laryngeal tuberculosis is a rare clinical entity and the incidence is significantly less than 1% of all tuberculosis. This case report highlights the co-existence of laryngeal cancer and TB in a 75-year-old man who presented to us with a 4-year history of hoarseness....
Open Access DOI:10.23937/2572-4193.1510029
M Waheed Roomi, Bilwa Bhanap, Aleksandra Niedzwiecki and Matthias Rath
Article Type: Research Article | First Published: February 21, 2017
Head and neck squamous cell carcinoma (HNSCC) is a devastating disease with poor prognosis. Matrix metalloproteinases (MMPs), specifically, MMP-2 and MML-9 play a critical role in tumorigenesis by their ability to modify tumor microenvironments, facilitating cell invasion and metastasis. We compared MMP secretion by various cytokines, inducers, mitogen, inhibitors that regulate MMP-2 and MMP-9 activities in FaDu and Tongue cancer cell lines....
Open Access DOI:10.23937/2572-4193.1510028
Sean Keane, Patrick Dillon and John E Fenton
Article Type: Case Report | First Published: January 21, 2017
A 48-year-old male presented for microlaryngoscopy and vocal fold polypectomy, which was complicated by polyp displacement into the lower respiratory airway during direct laryngoscopy and tracheal intubation. It is the first reported incidence of such a case. Following preoperative assessment and preparation, anaesthesia was induced and the airway secured using direct laryngoscopy and tracheal intubation with a microlaryngoscopy tube (MLT), which was reported uneventful....
Open Access DOI:10.23937/2572-4193.1510027
Andrew Petersen, Fariha Farid, Richard Klapchar, Sumit Bapna and Boris Karanfilov
Article Type: Case Report | First Published: December 03, 2016
We report the use of multiple balloon sinus dilation (BSD) catheters in the reduction of bilateral anterior table frontal sinus fractures in a 13-year-old male following sports injury. This case is unique in that it displays a less-invasive surgical correction of anterior table frontal sinus fractures using a new surgical tool and follows the literature-supported trend towards sinus preservation. More extensive frontal sinus fractures with severe comminution or displaced posterior table fracture...
Open Access DOI:10.23937/2572-4193.1510026
Abou-elfadl M, Benzaouia A, Abada R, Rouadi S, Roubal M and Mahtar M
Article Type: Clinical Study | First Published: December 03, 2016
The laryngeal tuberculosis incidence decreased significantly since the development of antituberculosis drugsand early detection of new cases. Currently, it represents less than 1% of cases of extrathoracic tuberculosis. As tuberculosis is endemic in Morocco, we continue to see this rare localization. Its clinical presentation is atypical and endoscopic aspects are polymorphic, hence the difficulty of diagnostic. The aim of the study is to report three different observations of the laryngeal loca...
Open Access DOI:10.23937/2572-4193.1510025
Susannah Orzell, Todd Falcone and Gregory Grillone
Article Type: Clinical Study | First Published: October 05, 2016
Killian-Jamieson Diverticulum (KJD) is a rare type of cervical esophageal diverticulum. It originates inferior to the cricopharyngeal muscle and lateral to the longitudinal muscle of the esophagus, and is closely associated with the recurrent laryngeal nerve (RLN). We report a case of KJD in a 78-year-old man treated with an open diverticulectomy with a nerve integrity monitor (NIM), and present a comprehensive literature review....
Open Access DOI:10.23937/2572-4193.1510024
Scott L Lee
Article Type: Perspective | First Published: September 01, 2016
Leaders often use the proverbial departed train to get people on board with unpopular changes, especially ones with little supporting evidence. Most hop on so as to not get left behind, but is the Maintenance of Certification (MOC) train heading in the right direction? In 2000, the American Board of Medical Specialties (ABMS) mandated all specialty affiliates to limit board certification (BC) to 10 years, rather than continue the lifetime certificate....
Open Access DOI:10.23937/2572-4193.1510023
Hanadi Fatani, Faraj Alotaiby and Saleh F Aldhahri
Article Type: Case Report | First Published: August 12, 2016
A 51-year-old female presented with 2 months' history of sore throat, change in voice, odynophagia, along with neck and thyroid nodule. CT/PET scan showed thickening of epiglottis with enhancement after intravenous contrast. Laser resection of epiglottis was done and histopathology revealed moderately differentiated neuroendocrine carcinoma. A week later patient underwent total thyroidectomy with bilateral modified radical neck dissection. Adjuvant external beam radiotherapy to the larynx and ne...
Open Access DOI:10.23937/2572-4193.1510022
Guler Yavas and Cagdas Yavas
Article Type: Review Article | First Published: July 12, 2016
Human papillomavirus (HPV) - associated head and neck squamous cell carcinoma (HNSCC) is an entity with unique clinical and molecular characteristics, which mainly arises from the palatine tonsils and base of the tongue. Nowadays, oropharyngeal cancers are increasing in incidence despite declining prevalence of smoking and in direct opposition to a decreasing incidence of all other HNSCC. An epidemic of HPV-associated oropharyngeal cancers seems to account for these incidence trends....
Open Access DOI:10.23937/2572-4193.1510021
Randolph B Capone, Michael M Kim and Dane J Genther
Article Type: Clinical Study | First Published: June 02, 2016
Background: Revision nasal valve reconstruction is one of the few treatment options available for patients with persistent nasal valve dysfunction after primary functional rhinoplasty. Revision nasal surgery is challenging, hampered by the presence of scar tissue, incorporated grafts, and the morbidity of obtaining additional autologous cartilage. Objective: In order to enhance nasal valve function while avoiding revision nasal surgery, a sublabial technique was developed to increase the project...
Open Access DOI:10.23937/2572-4193.1510020
Michael D Puricelli, Christopher I Newberry, Ryan M Neff, Michael S Cooperstock and Eliav Gov-Ari
Article Type: Research Article | First Published: June 01, 2016
469 charts were reviewed and 31 potential cases identified. 29 individuals were included with 20 successfully contacted. 11 cases met the classic definition (CD), 9 had intermittent cardinal symptom(s) (IS), and 9 had isolated periodic fever (IPF). Treatment included observation, steroid administration, and/or surgery (tonsillectomy or adenotonsillectomy). Steroids terminated each episode in all treated patients, 9/11 with CD and 11/18 with IS/IPF. When steroid treatment shortened the inter-epis...
Open Access DOI:10.23937/2572-4193.1510019
A Macchi, F De Bernardi, A Peirolo and D Simoncini
Article Type: Original Article | First Published: May 01, 2016
Rhinitis, a common condition throughout the world, are classified in non-allergic (NAR) and allergic rhinitis (AR). The data collected by recent studies show that NAR affects more than 200 million patients world-wide, among which 8% to 10% suffer from NARES and NARESMA. Nevertheless, respiratory diseases, and in particular rhinitis, are not considered real and serious diseases, and, as a result, they remain frequently underdiagnosed and undertreated despite the heavy burden they place on patient...
Open Access DOI:10.23937/2572-4193.1510018
Marciante Giulia Anna, Saibene Alberto Maria, Pisani Antonia, Biglioli Federico and Giovanni Felisati
Article Type: Case Report | First Published: April 30, 2016
A 73-year-old man, treated with a maxillary subperiosteal implant in 1985, was referred to our ENT clinic by his dental practitioner due to the onset of sudden edema, pain and purulent nasal discharge. Although the patient had experienced painful recurrent mobilization of the implant from 1995, he did not approach his dentist until 2006, when edema and purulent nasal discharge occurred. The radiologic imaging revealed a maxillary sinusitis with severe maxillary bone resorption and an oro-nasal/o...
Open Access DOI:10.23937/2572-4193.1510017
Sandhu JS, Rea PA and Ray J
Article Type: Case Report | First Published: April 02, 2016
In cases of intractable benign paroxysmal positional vertigo (BPPV) where conservative management has failed, surgical plugging of the semi-circular canal can provide an effective solution. Where bilateral disease is present, selecting the ear on which to operate can provide a challenge as there is often a pre-existing vestibulopathy and therefore surgery carries a considerable risk of chronic imbalance....
Open Access DOI:10.23937/2572-4193.1510016
Kokong DD, Yaro PJ, Embu HY, Nimkur LT, Iduh AA, Okwori ET, Adoga AS and Binitie OP
Article Type: Retrospective Study | First Published: April 01, 2016
Tracheostomy is a surgical procedure in which an incision is made in the anterior part of the neck in order to gain access into the trachea via a stoma. The resultant stoma can serve independently as an airway-tracheotomy or a site for a tracheostomy tube to be inserted-tracheostomy, so as to establish an alternate airway. This is a valuable life-saving operation employed in critical airway....
Open Access DOI:10.23937/2572-4193.1510015
Aleix Rovira, Marta Fulla Campi, Julio Nogues Orpi and Manel Manos Pujol
Article Type: Case Report | First Published: March 01, 2016
The Ortners syndrome or cardiovocal syndrome is an uncommon entity characterized by hoarseness due to left recurrent laryngeal nerve paralysis caused by identifiable cardiovascular disease. The most common conditions which may lead to Ortner's syndrome include mitral stenosis, aortic aneurysm, mitral valve prolapsed, cardiovascular surgery, aortic dissection etc. Herewith, we report the case of an atypical etiology of cardiovocal syndrome in a patient with a Pulmonary Artery Aneurysm (PAA)....
Open Access DOI:10.23937/2572-4193.1510014
May Lim, Annabelle C Leong and Vijayadwaja Desai
Article Type: Case Report | First Published: February 25, 2016
Tumor metastases from colorectal carcinoma to the thyroid gland are extremely rare. We present a case of metastatic colonic adenocarcinoma to the thyroid occurring in a longstanding multinodular goiter together with a review of existing literature. A 60 year old lady presented acutely with stridor in 2014 on a background of colorectal carcinoma diagnosed 2003 and multinodular goiter diagnosed in 2006....
Open Access DOI:10.23937/2572-4193.1510013
John E Nathan
Article Type: Editorial | First Published: February 02, 2016
This editorial takes a critical look at one aspect of healthcare which involves interaction between the fields of otolaryngology and pediatric dentistry. Not uncommonly on a daily basis each discipline makes use of general anesthesia to complete invasive procedures on young and pre-cooperative children. Myringotomies, tonsillectomies with and without adenoidectomies are commonplace in surgical schedules of hospitals and out-patient surgical centers....
Open Access DOI:10.23937/2572-4193.1510012
Abou-elfadl M, Elbousaadani A, Abada RL, Rouadi S, Roubal M and Mahtar M
Article Type: Case Series | First Published: January 30, 2016
The laryngocele is a dilation of the laryngeal saccule filled with air which communicates with the lumen of the larynx. It is pathology, rare but can be serious. Symptoms are varied and diagnosis is based on direct laryngoscopy and scanner. The treatment is purely surgical. We discussed, through three different cases, the clinical, radiological and therapeutic modalities of laryngocele....
Open Access DOI:10.23937/2572-4193.1510011
Catherine Weng, Rod Rezaee, Jason E Thuener and Chad Zender
Article Type: Retrospective Chart Review | First Published: January 27, 2016
Various imaging modalities have been used to evaluate lower extremity anatomy including traditional angiography, color flow Doppler (CFD), CT angiography (CTA) and MR angiography (MRA). We seek to compare these imaging modalities for preoperative planning of fibular osteocutaneous free flap reconstruction and to identify the optimal imaging method....
Open Access DOI:10.23937/2572-4193.1510010
Khaled M Mokbel, Waleed Moneir, Hossam Elsisi and Ahmed Alsobky
Article Type: Original Article | First Published: December 28, 2015
Our aim is to evaluate transcanal endoscopic approach in repair of subtotal tympanic membrane perforation in a trial to prevent conventional postaural approach. Our study was done in 80 patients with unilateral dry subtotal tympanic perforations. They were 44 males and 36 females. Their ages ranged from 18-50 years with mean of 33 years. Autograft thin (0.2 mm) auricular cartilage shield was used to repair tympanic membrane perforation. Patients were divided into two groups according to the appr...
Open Access DOI:10.23937/2572-4193.1510009
Peirolo Anna, Simoncini Daniela, Macchi Alberto, Graziani Daniela, Porcu Stefania and Nespoli Luigi
Article Type: Research Article | First Published: December 24, 2015
Background: An increasing proportion of patients have coexisting upper and lower airway disease. Therefore, the historic perspective of these allergen-induced disorders as distinct and separate entities is being displaced by current thinking that they are better described as a continuum of inflammation involving one common airway. Objectives:The aim of this study was to investigate the role that upper airway inflammation and therapy plays on lower airway situation. Methods:This study was perform...
Open Access DOI:10.23937/2572-4193.1510008
Rispoli L, Fontana F, Beretta M, Poggio CE and Maiorana C
Article Type: Review Article | First Published: November 15, 2015
Objectives: To analyze the biological principles of guided bone regeneration and to provide the clinician with information regarding the use of different membranes. Materials and Methods: The choosing criteria among different membranes and the clinical options are presented. Finally, the surgical technique is described in details. Results and Conclusions: Guided bone regeneration is one of the several surgical techniques that have been introduced in the last two decades for bone regeneration pri...
Open Access DOI:10.23937/2572-4193.1510007
Sheldon P. Hersh and William H. Rodgers
Article Type: Case Report | First Published: September 25, 2015
Glomangiopericytoma, also known as sinonasal hemangiopericytoma, is a rare sinonasal neoplasm that commonly occurs during the sixth or seventh decade of life, often presenting with complaints of nasal congestion and epistaxis. Identified in less than 0.5% of all sinonasal tumors, this typically indolent lesion is a different tumor from the far more common and aggressive so-called soft tissue hemangiopericytoma that arises in varying sites throughout the body....
Open Access DOI:10.23937/2572-4193.1510006
Steve Manzon, Malcolm Zola, Jared S Weiner, Rawle F Philbert, Kevin R. Torske, Donald B MacDougall, and Daniel Nadeau
Article Type: Case Report | First Published: September 18, 2015
Clinicians are often faced with diagnosing routine oral and maxillofacial pathology. Experience and training make such tasks relatively easy. Establishing differential diagnoses, and ruling out the most unlikely, usually will lead to an appropriate treatment plan. Occasionally, a pathologic presentation may significantly differ from the expected, and stump even an experienced clinician. It is imperative, when encountering an unknown or unusual lesion, to return to basics and approach the entity ...
Open Access DOI:10.23937/2572-4193.1510005
D'Ascanio Luca, Palmeri Annamaria Iole, Pappacena Marco and Piazza Fabio
Article Type: Case Report | First Published: September 09, 2015
The optimal surgical approach for extended parapharyngeal pleomorphic adenomas of the parotid gland is still controversial, also in relation to the possible complications of this type of surgery. We report our experience on 5 patients treated in the last 4 years with the 'extracapsular dissection-endocapsular decompression' surgical approach for parotid deep lobe extended adenomas. The surgical details are described. No complication in terms of temporary/permanent facial paralysis, sialocele or ...
Open Access DOI:10.23937/2572-4193.1510004
Article Type: Case Report | First Published: September 3, 2015
The most common presentation of Herpes Zoster infection in the head and neck region is Ramsay Hunt syndrome (RHS). RHS represents a complication of the Varicella Zoster Virus (VZV) infection, tipically presenting with the triad of ipsilateral peripheral type facial nerve paralysis, ipsilateral ear pain and erythematous vesicles in the external auditory canal. Herpes Zoster results from the reactivation of VZV in the dorsal root ganglia and RHS can be associated with trigeminal, abducent, glossop...
Open Access DOI:10.23937/2572-4193.1510003
Reid A. Waldman, Corey W. Waldman and Steven D. Waldman
Article Type: Review Article | First Published: August 28, 2015
First described in 1907 by James Ramsay Hunt, an American neurologist, Ramsay Hunt syndrome is the eponym given to a constellation of symptoms including a vesicular rash of the external ear and the ipsilateral two thirds of the tongue with associated paralysis of the seventh cranial nerve. The syndrome, which is also known as herpes zoster oticus and Hunt's syndrome, is believed to be caused by reactivation of dormant varicella-zoster virus (VZV) within the geniculate ganglion and associated sen...
Open Access DOI:10.23937/2572-4193.1510002
Claude F Harbarger and Brian J Wiatrak
Article Type: Case Report | First Published: August 21, 2015
Video Capsule Endoscopy (VCE) is an established means of evaluating the upper and lower aerodigestive tracts, with 3 companies now having received FDA clearance for their devices. The most prevalent risk of VCE is capsule retention, which infrequently results in bowel obstruction. In patients suspected of having a high risk of capsule retention, a dissolvable patency capsule is given a few days prior to the VCE procedure to ensure ultimate passage of the VCE device. Here we report what is, to ou...
Open Access DOI:10.23937/2572-4193.1510001
John E. Nathan
Article Type: Editorial | First Published: July 04, 2015
Pre-cooperative and severely apprehensive children have immature cognitive abilities, a restricted range of coping skills, brief or negligible attention spans, and virtually no experience coping with stress. For these children conventional communication strategies may often prove inadequate or inappropriate to overcome the behavioral manifestations of childhood dental fear and anxiety. Well- chosen pharmacological approaches has potential to permit in-office treatment, avoid aversive measures, a...
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