Obstetrics and Gynaecology Cases - Reviews is an open access peer-reviewed journal of obstetrics, gynaecology, focused to publish cases and reviews in all aspects of reproductive health. Articles are peer reviewed by clinicians or researchers expert in the field of Obstetrics and Gynaecology. The journal invites submissions from scientific and clinical reviews relevant to practice and case reports. The Journal will give publication priority to reviews and case reports.
The goal of the journal is to promote excellence in the clinical practice of obstetrics and gynecology and related fields close to Obstetrics and Gynaecology. The journal publishing a broad range of original, peer-reviewed papers, from scientific and clinical research to reviews relevant to practice and case reports.
Title: Obstetrics and Gynaecology Cases - Reviews
Editor-in-chief: Leslie Iffy
NLM title abbreviation: Obstet Gynecol Cases Rev
ISO abbreviation: Obstet Gynecol Cases Rev
Other titles: OGCR
Category: General Medicine
Peer review: Double blind
Review speed: 3 weeks
Fast-track review: 10 days
Publication format (s): Electronic and print
Publication policy: Open Access; COPE guide
Publication type(s): Periodicals
Publisher: ClinMed International Library
Country of publication: USA
Contact email: email@example.com
Articles Search by Keyword | Journal title | Author name | DOI
Open Access DOI:10.23937/2377-9004/1410240
A Case Report of Repeat Methotrexate Failure in Ectopic Pregnancy during In Vitro Fertilization
Carmine Guynn, PA-S and Kevin Alten, MD
Article Type: Case Report | First Published: April 14, 2023
Patients who undergo assisted reproductive technology, specifically in vitro fertilization (IVF), are at an increased risk of developing ectopic pregnancy. 90% are successfully treated with either single dose or multi-dose methotrexate intervention....
Open Access DOI:10.23937/2377-9004/1410239
Cesarean Delivery in Extracorporeal Membrane Oxygenation Dependent COVID-19 Parturients: A Case Report
Sannoor S Syed, MD, Abigail O Souryal, MD, Emily H Adhikari, MD, Kelechi B Anyaehie, MD, Joo H Shin, MD, Miakka N Jalloh, MD, Matthew J Leveno, MD, Pamela E Fox, MD and Olutoyosi T Ogunkua, MD
Article Type: Case Report | First Published: April 13, 2023
This case report describes two cases of unvaccinated pregnant patients with COVID-19 who progressed to ARDS requiring Venovenous (VV)-ECMO and successfully underwent cesarean delivery. The patients provided Health Insurance Portability and Accountability Act authorization and consent to publish these reports. This article conforms to case report (CARE) guidelines....
Open Access DOI:10.23937/2377-9004/1410238
Pregnancy Complicated by Non-Compaction Cardiomyopathy in the Mother and Fetus: A Case Report of Both Maternal Management and Prenatal Diagnosis
Eileen O'Connor, DO, Leah Saylor, DO, Suzanne O'Nan, MD and William Schnettler, MD
Article Type: Case Report | First Published: April 13, 2023
Left ventricular noncompaction cardiomyopathy (LVNC) is a rare form of familial cardiomyopathy attributed to failure of ventricular compaction during embryogenesis. Scant data exists regarding the management approach to pregnant patients with this condition. Additionally, few cases are reported in which both the mother and fetus are simultaneously affected by this condition during the antepartum period. ...
Open Access DOI:10.23937/2377-9004/1410237
Case Report on the Successful Management of Listeria monocytogenes Infection in the Third Trimester of Pregnancy
Caroline VASSALLO and Yves MUSCAT BARON
Article Type: Case Report | First Published: March 30, 2023
Listeria monocytogenes (LM) is a motile Gram-positive facultative anaerobe, which is primarily transmitted to humans through consumption of contaminated food. Examples include ready-to-eat meals, dairy products like milk and soft cheeses, cold meats and vegetables. In pregnant women, illness caused by LM infection, listeriosis, may occur asymptomatically or it may present with vague flu-like and/or gastrointestinal symptoms....
Open Access DOI:10.23937/2377-9004/1410236
Idiopathic Granulomatous Mastitis, Erythema Nodosum, and Arthritis (GMENA) in Pregnancy: A Case Report
Ashley Berlot, BS, Lesly Sanchez-Alvarez, BS, Nichelle Simmons, MD and Marie Ward, MD, MPH, FACS
Article Type: Case Report | First Published: March 25, 2023
Idiopathic granulomatous mastitis (IGM) is a rare breast condition most commonly seen in parous reproductive-age females. Rarely is IGM seen with erythema nodosum (EN), and more uncommonly, concurrent IGM, EN, and arthritis, also known as GMENA, particularly during pregnancy. This report details the first known documented case of GMENA in a pregnant individual within the United States....
Open Access DOI:10.23937/2377-9004/1410235
Management of Cervical Stenosis - Mechanical Dilatation Adjunct with Hormonal Therapy
Wong Pui Ying, MBChB, MRCOG and Yu Chun Hung, MBChB, MRCOG, FHKCOG, FHKAM (Obstetrics and Gynaecology), Cert HKCOG (Urogynaecology)
Article Type: Case Report | First Published: March 17, 2023
Madam C was a 39-year-old primiparous lady having history of one IVF pregnancy delivered by Caesarean section (CS). She was found cervical intra-epithelial neoplasm (CIN) 2-3 with loop electro-excision procedure (LEEP) performed 6 months after her delivery. 1.8 cm-thick, 2 cm-wide cervix was resected and diagnosed CIN 1....
Open Access DOI:10.23937/2377-9004/1410234
Successful Management of Intractable Supraventricular Tachycardia in Pregnancy
Ernalyn Joy R Endaya, M.D
Article Type: Case Report | First Published: March 17, 2023
Pregnancy is a complex state in a woman's life. It is associated with anatomical and physiologic changes that greatly affect not only the mother but the living fetus inside her womb. This is a case of a 22-year-old woman at 36 5/7 weeks age of gestation presented with intractable tachycardia. The patient presented at the emergency room in cardiorespiratory distress in conjunction with preterm labor. The dilemma of the management would be thoroughly discussed in consideration of the present mater...
Open Access DOI:10.23937/2377-9004/1410233
Can a Specific 3.6:1 Myoinositol (1100 mg) to D-chiro-inositol (300 mg) Ratio-Based Food Supplement Increase Pregnancy Rates in Advanced Age Conception? A Series of Case Reports
Jorge Iranzo-Sola, Clara Limonta-Bonitto, Bibiana Rodríguez-Jiménez and Silvia Tapiador- Albertos
Article Type: Case Report | First Published: March 09, 2023
Over the last decades, there has been a progressive delay in the mean maternal age of childbirth in industrialized countries due to multifactorial causes. The proportion of women giving birth for the first time at 35 years or older is now higher than decades ago. Pregnancy in this age group is considered advanced age pregnancy. As age increases, there is a rising risk of infertility, mainly due to the inability to conceive, as well as gestational and perinatal complications, which can potentiall...
Open Access DOI:10.23937/2377-9004/1410232
A Case Report on Successful Management of Complete Placenta Previa with Internal Iliac Artery Ligation
Nalini Thiruvengadam and Kavitha Gautham
Article Type: Case Report | First Published: February 10, 2023
Placenta previa is a complex and extremely challenging scenario as it may result in serious life-threatening conditions like postpartum hemorrhage (PPH). In this case report we present a 32-year-old Primi with 37 weeks of gestational age who approached a multispeciality private hospital at Chennai with complaints of bleeding per vagina around 32 weeks. The Ultrasonogram finding revealed type- 3 placenta previa posterior and the patient was hospitalized. The concise steps taken in the managemen...
Open Access DOI:10.23937/2377-9004/1410231
Labial Agglutination in a Reproductive Age Woman
Annie Ruth B Dayu, MD and Ma. Isidora Margarita Yap-Garcia, MD
Article Type: Case Report | First Published: November 05, 2022
A 25-year-old nulligravid was consulted due to inability to have sexual intercourse accompanied by chronic urinary hesitancy, dribbling, and dysmenorrhea. On gynecologic pelvic examination, she presented with complete, adult- onset fusion of the labia minora. This paper describes a stepwise management of a reproductive-age woman with complete labial fusion. Treatment goals include etiological determination, anatomic correction, restoration of normal sexual function, improvement of genitourinary...
Open Access DOI:10.23937/2377-9004/1410230
Diapers and Dialysis: A Case Report on Postpartum Atypical Hemolytic Uremic Syndrome
Meghan St John, MD and Maritsa Scoulos-Hanson, DO
Article Type: Case Report | First Published: October 19, 2022
While thrombotic microangiopathy (TMA) syndromes such as thrombotic thrombocytopenic purpura (TTP), hemolytic uremic syndrome (HUS) and atypical hemolytic uremic syndrome (aHUS) present similarly with hemolytic anemia, thrombocytopenia, and renal injury, their etiology and treatment differs. This poses challenges to prompt diagnosis and treatment....
Open Access DOI:10.23937/2377-9004/1410229
Abortion in Patient with Obstructive Longitudinal Vaginal Adhesion following Vaginal Prolapse Surgery: A Case Report
Arielle W Fein, MD, Madeline A Dick-Biascoechea, MD, Gracie Nichols, CRNP and Jessica K Lee, MD, MPH
Article Type: Case Report | First Published: October 12, 2022
A vaginal adhesion is an uncommon complication of vaginal surgery. While treatment options for radiation- induced vaginal stenosis and vaginal septum have been well-characterized, there is little to guide surgeons providing care to patients with intravaginal adhesions. This report presents a multigravida with history of anterior and posterior colporrhaphy and perineoplasty referred from an outpatient abortion clinic for a dense longitudinal adhesion obstructing the cervix....
Open Access DOI:10.23937/2377-9004/1410228
Eclampsia and Postpartum Depression in the Setting of Recurrent Prenatal COVID-19
Olivia Cook, Sahar Zargar and Wanda Torres
Article Type: Case Report | First Published: September 30, 2022
We present a case of gestational hypertension, eclampsia, and postpartum depression in a 39-year-old nulliparous pregnant patient following multiple prenatal severe acute respiratory syndrome-related coronavirus 2 (SARS- CoV-2) infections. After an initial mild first trimester case of coronavirus disease-19 (COVID-19), the patient received a 2-dose mRNA vaccine against SARS-CoV-2....
Open Access DOI:10.23937/2377-9004/1410227
Complete Androgen Insensitivity Syndrome: A Rare Case with 47, XXY/46, XY Mosaic Karyotype and Literature Review
Yu Hong, Chun-ke Li and Hai-qi Liang
Article Type: Case Report | First Published: August 29, 2022
Androgen insensitivity syndrome (AIS) is an X-linked recessive genetic disease caused by the absence or defects of androgen receptor (AR). Due to the insensitivity to androgen, clinically, patients often manifest as sexual development disorder. According to the grade of the remaining AR function, AIS is classified as complete (CAIS), partial (PAIS) or mild (MAIS). A 14-year-old Chinese child, raised as female, presents with primary amenorrhea....
Open Access DOI:10.23937/2377-9004/1410226
A Case of Growing Teratoma Syndrome with Gliomatosis Peritonei in The Setting of Ovarian Immature Teratoma
Joshua Daum, BS, Lauren Griebel, MD and Paul Magtibay, MD
Article Type: Case Review | First Published: July 20, 2022
31-year-old nulliparous female with grade 2 immature teratoma presented following presumed treatment failure. Tumor markers remained consistently normal. Biopsies demonstrated gliomatosis peritonei (GP). Despite chemotherapy, tumor growth persisted. She then underwent fertility-sparing cytoreductive surgery. Final pathology showed no evidence of malignancy and presence of only mature teratoma cells....
Open Access DOI:10.23937/2377-9004/1410225
Case Report: Vulvar Condylomas - New Local Synergistic Treatments
Zuramis Estrada Blanco
Article Type: Case Report | First Published: May 21, 2022
Condyloma acuminata or genital warts are the clinical expression of infection from certain types of human papillomavirus (HPV) that are considered to have low oncogenic risk (No. 6 and No.11). They are currently considered one of the most common sexually transmitted diseases with increasing incidence among most populations. The lesions present and extend in numerous forms (from very localized forms and limited disease to very extensive forms with multi-focal involvement of the anogenital tract)....
Open Access DOI:10.23937/2377-9004/1410224
Vulvar Granular Cell Tumor in 51-Year-Old Female: A Case Report
Sophia Salas, Nicholas Haslett and Elise N Everett
Article Type: Case Report | First Published: April 21, 2022
A 51-year-old G3P2012 female presented to the gynecology clinic after referral from her primary care provider for a lump in the vulva. The lump was first noticed two years prior, at which time it was pea-sized per patient report and has slowly grown since. The patient reports the lump is not painful or pruritic but has become more bothersome due to its periclitoral location. There was no drainage, bleeding, ulceration, or inflammation at the site of the lump and no changes in vaginal bleeding or...
Open Access DOI:10.23937/2377-9004/1410222
Vaginal Dysbiosis Management and the Efficacy of a Non- Hormonal Hyaluronic Acid-Based Vaginal Gel (Palomacare®) as an Adjuvant Treatment: The Palomascopia Survey
Fernando Losa, Santiago Palacios, Silvia P González Rodríguez, Laura Baquedano, Danial Khorsandi and María José Muñoz
Article Type: Brief Report | First Published: March 31, 2022
To understand the diagnosis and treatment strategies for vaginal dysbiosis (VD), and the efficacy of Palomacare® vaginal gel as an adjuvant treatment and for relapse prevention. The Palomascopia study was a digital survey conducted from January to March 2021. The data was analyzed once collected. In Spain, 61% of gynecologists perform a vaginal culture to diagnose VD. To treat bacterial vaginosis 67% of gynecologists, prescribe topical antibiotics and 17% recommend prebiotics, meanwhile 71% of ...
Open Access DOI:10.23937/2377-9004/1410221
A Unique Case of Complex Pelvic Arterial Collateralization Requiring Multidisciplinary Approach to Prolapsing Submucosal Leiomyoma
Amanda P Stanton, PA-C, Charles Ritchie, MD and Christopher DeStephano, MD
Article Type: Case Report | First Published: March 31, 2022
Leiomyoma are the most common benign tumor of the reproductive tract in premenopausal women. Uterine artery embolization has been accepted as a minimally invasive option for the treatment of leiomyoma. While pelvic arterial embolization has shown promising safety and effectiveness in controlling postpartum hemorrhage, no studies have reviewed its clinical application for the prophylactic decrease of hemorrhage risk following minimally invasive therapies for fibroids. We present a case and discus...
Open Access DOI:10.23937/2377-9004/1410220
Vaginal Delivery in Pregnancy with Buschke-Löwenstein Tumor (Giant Condyloma Acuminatum)
Marta Narváez-Salazar, MD, Leyre Ruiz-Campo, MD, Javier Navarro-Sierra, MD, Peña Dieste- Pérez, MD, María Jesús Puente-Luján, MD, Marta Lamarca-Ballestero, MD, PhD and Laura Baquedano-Mainar, MD, PhD
Article Type: Case Report | First Published: March 31, 2022
The purpose of this paper is to present the case of a pregnant woman with diagnosis of Buschke-Löwenstein tumor at the beginning of labor, exposing the management and performing a review of the literature on the matter. A pregnant woman in the 37th week of gestation diagnosed with Buschke-Löwenstein tumor at the time of the delivery. Her medical history did not reveal any characteristics. Due to the predominantly perineal spread, with no warts in the vagina or birth canal, the labor progress w...
Open Access DOI:10.23937/2377-9004/1410219
Do the Neutrophil/Lymphocyte Ratio and the Platelet/ Lymphocyte Ratio Have an Effect on Birthweight, Gestational Age and Severity of Prematurity?
Ayca Nazli Bulut and Venhar Ceyhan, MD
Article Type: A Retrospective Study | First Published: February 19, 2022
There are studies in literature which have reported that the neutrophile to lymphocyte ratio (NLR) is associated with gestational diabetes, pre-eclampsia, the severity of pre-eclampsia, premature prelabour rupture of membranes (PPROM) and hyperemesis gravidorum. There may also be an association with healthy pregnancies without any pathological conditions. The aim of this study was to investigate whether the neutrophil/lymphocyte ratio (NLR) and the platelet/lymphocyte ratio (PLR) have an effect ...
Open Access DOI:10.23937/2377-9004/1410218
Polycystic Ovary Syndrome (PCOS) Presenting with Delayed Menarche and Clitoromegaly
Sa’adatu T Sule and Shedrach Anekwe
Article Type: Case Report | First Published: February 17, 2022
Polycystic ovary syndrome can present with various features including delayed menarche, amenorrhoea, and enlarged clitoris, as was the case with the patient presented here. The diagnosis of PCOS can be challenging especially in young women and managing the condition may be complicated especially where metabolic effects such as type 2 diabetes occur as demonstrated in this case. A 22-year-old student presented in May 2018 with a history of amenorrhoea for one year. Her first menses was 2 years p...
Open Access DOI:10.23937/2377-9004/1410217
Microglandular Hyperplasia of the Cervix- A Diagnostic Challenge
Sara Maria Bernardes da Cunha, Ana Marta Pinto, Sofia Raposo, Maria do Carmo Cruz, Rita Sousa, Luís Sá and Amália Pacheco
Article Type: Case Report | First Published: January 22, 2022
Microglandular hyperplasia was described for the first time in 1968 and referred to a benign lesion of the cervix, which mimics adenocarcinoma. The reported incidence is about 15%, leading to insufficient experience in pathological identification. The association with hormonal exposition has been assumed. However, it is not consensual. We report a clinical case of a 22-years-old women manifesting otorrhagia. In the physical assessment, a suspicious exophytic bulky lesion was observed. The macros...
Open Access DOI:10.23937/2377-9004/1410216
Advanced Abdominal Pregnancy at Full Term with Live Fetus Invading Colon Mesentery in a Patient with Relative Infertility, Case Report
Hagar G Okda, Nadeem Hamed, Samar Abdel Aziz and Ismail E Khalifa
Article Type: Case Report | First Published: December 31, 2021
Abdominal pregnancy is rare, it accounts for about 1% of ectopic pregnancies. It has a high misdiagnosis rate especially if the case is presented for the first time at advanced gestational age. In most of the published cases, abdominal pregnancies do not get to full term gestation and usually the end result is the extraction of a dead fetus or congenitally malformed live fetus. We report a case of undiagnosed advanced abdominal pregnancy at full term that was presented to our hospital for electi...
Open Access DOI:10.23937/2377-9004/1410215
Delayed, Stable Presentation of Complete Uterine Rupture
Melody Rasouli, Alyssa Stiff, McKenna Geary and Samet Albayrak
Article Type: Case Report | First Published: November 15, 2021
We present a rare case of fetal demise with delayed presentation of complete UR in a hemodynamically stable, asymptomatic 32-year-old woman with a history of one low transverse cesarean section and two subsequent uncomplicated vaginal births after cesarean delivery (VBAC). Complete prelabor ruptures in women with a previous uterine scar are rare but are associated with catastrophic outcomes. Intrauterine fetal demise should be recognized as a sign, not necessarily a sole diagnosis, until other...
Open Access DOI:10.23937/2377-9004/1410214
Resuscitation with Intact Cord Reduces the Rate of Asphyxia at 5 Minutes
Lixia Zheng, RM and Hong-yu Zhang
Article Type: Case Report | First Published: November 15, 2021
Retrospective cohort study. Asphyxia babes 104 cases from Jan. 2011 to Dec. 2013 in the seconde maternal and neonate hospital in Jinan Shandong province received immediate cord clamping and transferring to the emergence-bed for the resuscitation process were enrolled as controlled group; experimental group were those asphyxia babes 94 cases from Jan. 2014 to Dec. 2016 where they were resuscitated with intact cord in delivery bed. Data was recorded from the clinical record in the hospital. Inform...
Open Access DOI:10.23937/2377-9004/1410213
Intramural Pregnancy Misdiagnosed as Gestational Trophoblastic Neoplasia: Case Report and Review of the Literature
Lejing Zang and Yan Hu
Article Type: Case Report and Literature Review | First Published: November 13, 2021
To date, only a few cases of intramural pregnancy have been recorded. We aim to report an uncommon case of intramural pregnancy misdiagnosed as gestational trophoblastic neoplasia, emphasizing that earlier surgical intervention may contribute to timely diagnosis and precise treatment. Relevant articles published over the past five years were identified through a literature searching, and related references in those literatures were also manually searched to find additional articles. Nineteen ...
Open Access DOI:10.23937/2377-9004/1410212
Intrahepatic Cholestasis in Pregnancy: Increased Surveillance and the Role of Bile Acids in a Patient with History of Fetal Demise
Noah Ryan Begley and Abdalyz Frias Beltran
Article Type: Case Report | First Published: October 11, 2021
Intrahepatic cholestasis of pregnancy (ICP) is a known risk for fetal demise and premature delivery. We describe the case of a third-trimester patient with ICP that would have gone unnoticed based on laboratory reporting. Symptoms presented two weeks after laboratory values consistent with ICP were obtained, and serial labs fell below the threshold despite persistent symptoms. The diagnosis was further complicated when the types of bile acids and the ranges for normal varied between facilities. ...
Open Access DOI:10.23937/2377-9004/1410211
Successful Treatment of a Cesarean Scar Ectopic Pregnancy Using a Novel Approach with Oral Mifepristone followed by Trans Cervical Suction Evacuation with Prophylactic Tranexamic Acid: A Case Report
Muhunthan K, MBBS, MS, FRCOG, Anton Jenil Amirthanathan, MBBS, MD, Raguraman S, MBBS, MD, MRCOG and Guruparan K, MBBS, MD
Article Type: Case Report | First Published: October 09, 2021
Cesarean scar pregnancy is a rare form of ectopic pregnancy where the conceptus is implanted at the site of a previous cesarean section scar which pauses lifethreatening complications if not diagnosed and managed timely. Though numerous types of treatment approaches have been described there is no consensus on the optimal treatment modality which is a challenge to clinicians. Current treatment approaches are a combination of medical and surgical interventions with varying success rates and compl...
Open Access DOI:10.23937/2377-9004/1410210
Case Report: Rare Presentation of Invasive Mole Following Term Pregnancy after Assisted Reproduction
S Raguraman, K Muhunthan and P Kabileshan
Article Type: Case Report | First Published: October 06, 2021
Invasive mole (IM) is one of the Gestational trophoblastic neoplasia lesions, characterized by local invasion of trophoblastic with rare distal spread. It could follow any type of pregnancy and commonly arising from a complete hydatidiform mole (CHM). Pathogenesis of hydatidiform mole due to an underlying oocyte defect. Embryos are examined for triploidy to exclude dispermic fertilization in assisted reproduction technology (ART). Besides, several potential mechanisms and risk factors had been d...
Open Access DOI:10.23937/2377-9004/1410209
Primary Umbilical Endometriotic Nodule with an Ultrasound Incidental Finding of Ovarian Endometrioma and a Solitary Intramural Uterine Myoma: A Case Report
Ifeanyi Martin Okoye, Olufemi Omiwole and Oluwatoyosi Mary Adeoye
Article Type: Case Report | First Published: September 15, 2021
Endometriosis is the presence of endometrial stroma outside the uterine cavity. Endometrioma (chocolate cyst) is the most common form of endometriosis. Primary umbilical endometriosis (PUE) is rare, with a prevalence of < 1% of endometriosis cases. Our case is a 25-year-old nulliparous female with a three-year history of infertility presenting with primary umbilical endometriosis and an abdomino-pelvic ultrasonography finding of a right endometrioma, and a solitary intramural uterine myoma. Thes...
Open Access DOI:10.23937/2377-9004/1410208
A Suspected Ovarian Cancer in a Postmenopausal Woman That Turned Out to Be a Broad Ligament Leiomyoma with Extensive Hydropic Degeneration
Thoshya Polepalle, Navindi Hasara Fernandopulle and Jaydip Raut
Article Type: Case Report | First Published: July 26, 2021
Leiomyomas affect 30% of all women of reproductive age. They can be of uterine or extrauterine origin. Broad ligament leiomyomas are a type of extrauterine leiomyomas, its incidence comprising less than 1%. It can undergo degenerative changes. Extensive hydropic degeneration is a rare occurrence and is commonly reported in association with pregnancy. It is a close mimic of malignancy due to its rapid growth and atypical imaging appearances 3 which can lead to diagnostic challenges. We present a ...
Open Access DOI:10.23937/2377-9004/1410207
Administration of a Divided Dose of Carboplatin Following Carboplatin-Induced Syndrome of Inappropriate Secretion of Antidiuretic Hormone (SIADH): A Case Report
Suguru Fujitsuka, Naoki Horikawa, Teruki Yoshida, Sae Yu, Ryosuke Kuroda, Mitsuru Tsuji, Maki Umemiya, Rei Gou, Yoshihide Inayama, Hirohiko Tani and Kenzo Kosaka
Article Type: Case Report | First Published: July 30, 2021
Chemotherapy-induced severe hyponatremia is a lifethreatening condition. Platinum-based agents play a key role in ovarian cancer treatment, but they are more likely to cause hyponatremia than other anti-cancer agents. The optimal strategy for treating ovarian cancer in the case of severe hyponatremia induced by the platinum agent remains unclear. We report the case of 77-year-old women with multiple peritoneal recurrences five years and eight months after surgery for ovarian clear cell carcinoma...
Open Access DOI:10.23937/2377-9004/1410206
Robotic Resection of a Large Degenerating Leiomyoma
Cari Eckman, Andrea L Buras, Daniel K Jeong, Ardeshir Hakam and Hye Sook Chon
Article Type: Case Report | First Published: July 28, 2021
A 56-year-old African American, multiparous, postmenopausal woman presented with a cystic left adnexal mass found incidentally on her yearly transvaginal ultrasound to monitor fibroids. She had a known history of uterine leiomyomas for which she had not required treatment. Her only previous abdominal surgery was a tubal ligation. Pelvic examination demonstrated a mobile, nontender uterus with a large palpable left adnexal mass that was smooth and mobile. A transvaginal ultrasound demonstrated a ...
Open Access DOI:10.23937/2377-9004/1410205
HPV Positive Oropharyngeal Cancer in Two Gynaecologists Exposed to Electrosurgical Smoke Plume
Jim Parker and Jonathan Clark
Article Type: Case Report | First Published: July 26, 2021
Every day thousands of health-care professionals are exposed to surgical smoke plume produced by tissue destruction during electrosurgical procedures. There has been increased awareness of the possible health hazards associated with inhalation of a range of biological contaminants that have been identified in the aerosol created. This has corresponded to an increased number of observational and experimental studies aimed at identifying the specific risks to medical personnel and ways to control ...
Open Access DOI:10.23937/2377-9004/1410204
Termination of Pregnancy with Pseudomyxoma Peritonei Secondary to Ovarian Mucinous Adenocarcinoma: A Video Case Report
Abdalla Mousa, Islam T Elkhateb, Ahmed SA Soliman and Mario Rizk
Article Type: Case Report | First Published: June 26, 2021
A 27-years-old primigravida, at 30 weeks of gestation, was transferred to our tertiary care obstetric centre. On initial assessment, she was found to have fever (38.5 °C), dyspnoea (26 breaths per minute), altered mental status (drowsiness), tachycardia (110 beat per minute) and hypotension (80/50 mmHg). The patient started feeling sick following percutaneous ultrasound (US) guided ovarian cyst aspiration that was performed at an outpatient clinic 2 days before her presentation. Basically, the ...
Open Access DOI:10.23937/2377-9004/1410203
Neoadjuvant Chemotherapy during Pregnancy in Cervical Cancer Patient Followed by Simultaneous Cesarean Section and Radical Hysterectomy: A Case Report
Olga P Matylevich, MD
Article Type: Case Report | First Published: June 20, 2021
Current recommendations for pregnant women with cervical cancer depend on several factors, such as the stage of the disease, the gestational age at the time of diagnosis, and the patient’s desire to maintain the pregnancy. This report describes the case of a 24 weeks pregnant woman with stage IB2 cervical cancer who was successfully treated with three cycles of platinum-based neoadjuvant chemotherapy followed by a simultaneous Сaesarean section and radical hysterectomy. Her newborn daughter w...
Open Access DOI:10.23937/2377-9004/1410202
A Case Report of Possible Superfetation with Evidence of Ultrasound Findings, Gestational Age Calculations and Postnatal Complications
Taylor Alten, PA-S and Kevin Alten, MD
Article Type: Case Report | First Published: June 18, 2021
Superfetation is a when second ovum is fertilized after there is already presence of an embryo in the uterine cavity. Human superfetation is extremely rare with less than 10 cases in the literature. According to previous research, the diagnosis of superfetation is suspected when there is a growth discrepancy in a multiple pregnancy. We present a case of a 35-year-old gravid 1 para 0 who presented to her OB/GYN at 7 weeks by known last menstrual period (LMP) for her first prenatal visit. She was ...
Open Access DOI:10.23937/2377-9004/1410201
Eclampsia at 20 Weeks of Gestation: A Case Report
Mary Sue Makin
Article Type: Case Report | First Published: June 14, 2021
A 23-year-old primigravida with unknown last menstrual period and 20 weeks gestation by ultrasound presented to Daeyang Luke Hospital in Lilongwe, Malawi with a history of headache, fever, vomiting and new-onset of convulsions. At the time of her admission the full blood count instrument at our hospital was out of service. A rapid blood test for malaria was positive. After an initial blood pressure of 164/127 and 3+ proteinuria on urinary dipstick the diagnosis of eclampsia was made. She was giv...
Open Access DOI:10.23937/2377-9004/1410200
Endometrial Stromal Nodule: A Case Report
Şerife Özlem Genç, MD, Aliye Nigar Serin, MD and Burcu Yılmaz, MD
Article Type: Case Report | First Published: April 24, 2021
The endometrial stromal nodule (ESN) is the rarest subtype of endometrial stromal tumors (ESTs) that’s why experience with ESN is limited. ESN could mimic highly cellular leiomyomas, usually seen in the premenopausal age. Patients present with non-specific symptoms such as abnormal bleeding, lower abdominal pain, or maybe asymptomatic. Our patient was 46 years old women suffering from abnormal uterine bleeding and lower abdominal pain and had no desire to protect fertility. The preoperative di...
Open Access DOI:10.23937/2377-9004/1410199
Placental Site Nodule (PSN): An Uncommon Diagnosis with a Common Presentation
Sneha GS and Ramesh Kumar R
Article Type: Case Report | First Published: April 24, 2021
Placental site nodule is an uncommon, benign, generally asymptomatic lesion of trophoblastic origin, which may often be detected several months to years after the tenancy from which it resulted. PSN usually presents as menorrhagia, intermenstrual bleeding or an abnormal pap smear. PSN is benign, but it is important to distinguish it from the other benign and malignant lesions like decidua, placental polyp, exaggerated placental site and placental site trophoblastic tumor and squamous cell carcin...
Open Access DOI:10.23937/2377-9004/1410198
Gitajali Kumari, Vaishali Taralekar, Suchita Dhabadkar and Jyoti Rathi
Article Type: Case Report | First Published: April 05, 2021
Ovarian cancer is the third most common cancer in Indian women, accounting for 3% of all malignancies and 6% of deaths from cancer. It is fifth most common cause of death from malignancy in women. Ovarian cancer is associated with low parity and infertility. Because parity is inversely related to the risk of ovarian cancer, having at least one child is protective for the disease, with a risk reduction of 0.3 to 0.4. This case is presented to highlight the varied presentation of ovarian masses an...
Open Access DOI:10.23937/2377-9004/1410197
A Case of Incarceration of the Gravid Uterus & the Ehlers- Danlos Syndromes with Literature Review
Morgan H Campbell, BS, Adam T Sandlin, MD, Paul J Wendel, MD and M Luann Racher, MD
Article Type: Case Report with Literature Review | First Published: April 05, 2021
Incarceration of the gravid uterus (IGU) poses significant risk for maternal and fetal complications during pregnancy. Several risk factors have been implicated in the development of an incarceration of the gravid uterus; however, the association between IGU and the Ehlers-Danlos syndromes (EDS) has not been reported. A 28-year-old female at 24 weeks gestational age presented with concern for preterm labor. IGU was diagnosed and she underwent surgical reduction of the incarceration via midline l...
Open Access DOI:10.23937/2377-9004/1410196
A Multidisciplinary Approach to the Patient with Deep Infiltrating Endometriosis
Ulrich, Amanda, MD, Arabkhazaeli, Moona, MD, Dellacerra, Gary, DO, Malcher, Flavio, MD and Lerner, Veronica, MD
Article Type: Case Report | First Published: April 05, 2021
Endometriosis is a prevalent condition that affects women’s health-related quality of life worldwide and deep infiltrating endometriosis represents a subset of these patients who are most severely affected. Due to the complex nature of deep infiltrating endometriosis (DIE) a preoperative suspicion for the condition allows for coordination of a multidisciplinary approach to surgical planning, a key to successful surgical resection. We describe three patient cases to highlight the importance of ...
Open Access DOI:10.23937/2377-9004/1410195
Type 3 Transformation Zone of the Cervix and Risk of Missed Lesions during Cervical Cancer Screening with Visual Methods: A Case Report from Cameroon
Simon M Manga, PhD, Alan T Tita, MD, PhD, Warner K Huh, MD, Calvin Ngalla, BNS and Margaret I Liang, MD, MS
Article Type: Case Study | First Published: March 22, 2021
Type 3 transformation zone (TZ) of the cervix poses a challenge in cervical cancer screening with visual techniques because of the potential for missing important precancerous lesions. This paper presents two case reports of women with Type 3 TZs who were screened with visual methods at the Cameroon Baptist Convention Health Services, had reassuring screening results, but presented soon after with invasive cervical cancer (ICC)....
Open Access DOI:10.23937/2377-9004/1410194
Guillain-Barré Syndrome Complicating First Trimester Pregnancy: A Case Report and Review of Literature
Aniska W Fortuin, Anne-Lotte F van der Kooi, Laus JMM Mulder and Irene AM van der Avoort
Article Type: Case report and Review of Literature | First Published: March 18, 2021
Guillain-Barre syndrome (GBS) is a rare immune mediated polyradiculoneuropathy, causing muscle weakness, hyporeflexia and dysesthesia. There is no specific guideline for management of GBS during pregnancy in general and first term in particular. We report a 26-year-old nullipara who developed GBS in early pregnancy and present an overview of recommended treatment, maternal and fetal outcomes and pathogens associated with GBS in women diagnosed in first trimester pregnancy. We performed a systema...
Open Access DOI:10.23937/2377-9004/1410193
Benign, Self-Resolving Subcutaneous Emphysema and Abdominal Crepitus after Open Gynecologic Surgery
Conway Xu, MD, John C Elkas, MD and Chad A Hamilton, MD
Article Type: Case Report | First Published: February 18, 2021
Abdominal crepitus and associated subcutaneous emphysema on imaging following open gynecologic surgery typically signals life-threatening complications including perforated viscus and necrotizing fasciitis, which require prompt intervention. This case is the second to date after open gynecologic surgery where, after extensive workup, significant subcutaneous emphysema of uncertain etiology was diagnosed with a benign and self-resolving course without any long term sequalae. Subcutaneous emphysem...
Open Access DOI:10.23937/2377-9004/1410192
Intra-Operative Ultrasound Assessment of a Myometrial Cyst with Fertility-Sparing Myometrial Cystectomy
Gillian A Corbett, Claire Thompson, Zibi Marchocki and Noreen Gleeson
Article Type: Case Report | First Published: February 15, 2021
Benign leiomyoma can undergo degeneration that result in unusual clinical and radiological presentations. Diffuse hydropic fibroid degeneration resulting in myometrial cyst formation is very rare. Here we describe intra-operative ultrasound recognition of this phenomenon. A 35-year-old nulliparous woman presented to the Gynaecology Oncology Clinic with menorrhagia and pressure symptoms. Abdominal examination revealed an abdominal mass extending to the umbilicus. Ultrasound showed complex pelvic ...
Open Access DOI:10.23937/2377-9004/1410191
Clinical Implications and ESHRE/ESGE Classification of Mullerian Anomalies: A Case Series
Uma Gupta, Vartika Tripathi and Priya Sharma
Article Type: Case Series | First Published: February 10, 2021
Mullerian or paramesonephric ducts form the female genital tract and any deviation from the normal can lead to Mullerian anomalies. Depending on the type of Mullerian anomaly; the presentations, required investigations and treatment options vary considerably and so does the counseling regarding the condition. Due to the highly varied profile of patients with Mullerian anomalies, a number of classification systems have been proposed to aid in their diagnosis and management. A thorough knowledge o...
Open Access DOI:10.23937/2377-9004/1410190
Case Report: Management of an Early Third Trimester Large Adnexal Mass in a Singleton Pregnancy
Lindsay Rucker, MD, Zachary Walker, MD and Brian Casey, MD
Article Type: Case Report | First Published: January 29, 2021
Adnexal masses are increasingly being diagnosed in pregnancy. They are typically either managed expectantly or surgically in the early second trimester; however, limited reports on interventions for management in the third trimester. A 34-year-old G2P1001 patient had a right ovarian cyst found at 82/7 measuring 10.35 × 10.2 × 8.38 cm. It increased to 15 × 11 × 15 cm at 30 1/7 and became symptomatic. She underwent percutaneous drainage (PCD) at 30 2/7 with a decrease in size to 8.8 × 4.2 × ...
Open Access DOI:10.23937/2377-9004/1410189
Case Report of Pregnancy with Huge Fibroid
Hemali Bharat Karia, MBBS, DGO, Deepa Maniar, MBBS, MD and Ketan Gosai, MBBS, MD
Article Type: Case Report | First Published: January 21, 2021
Their presence has been linked to spontaneous abortion, intrauterine growth restriction (IUGR), anemia, multiple blood transfusions, infection, pain, degeneration, malposition of foetus, premature labour, uterine inertia, placental abruption, postpartum hemorrhage, retention of the placenta, increased rates of cesarean section, hysterotomy, obstetric hysterectomy...
Open Access DOI:10.23937/2377-9004/1410188
Modification of Staged Embolization-Hysterectomy Procedure for Placenta Accreta to Avoid Non-Target Embolisation of Ovaries
Catherine L Davis, Bishoy Hanna, John Keogh, Eisen Liang and Amir Hanna
Article Type: Case Series | First Published: December 21, 2020
Placenta accreta spectrum describes the abnormal adherence of the placenta to, into or beyond the myometrium of the uterus. Three women who were antenatally diagnosed with placenta accreta underwent a modified staged embolization- hysterectomy procedure consisting of; placement of prophylactic bilateral common iliac artery occlusion balloons, a classical caesarean section, surgical dissection of the ovaries from the uterus, embolization of the uterine arteries, followed by hysterectomy. The thre...
Open Access DOI:10.23937/2377-9004/1410187
A Pelvic Mass Masquerading as High Stage Malignancy - An Interesting Presentation of Psuedo-Meigs Syndrome
Cathy Monteith, PhD, Tamara Kalisse, Robert A Farrell, Yulia Shahabuddin and Thomas John D’Arcy, MD
Article Type: Case Report | First Published: December 21, 2020
The lifetime risk of developing an ovarian malignancy is reported to be 1.4%. Invasive epithelial ovarian cancers have the highest prevalence in women between 60-64 years while germ cell or borderline tumours pre-dominate in women under 40 years. We report the case of a 33-yearold nulliparous woman with a 7 kg leiomyoma, extensive endometriosis and several radiological features suggestive of a high stage ovarian malignancy. Meigs syndrome typically presents as a triad of ascites, pleural effusio...
Open Access DOI:10.23937/2377-9004/1410186
Trocar-Site Herniation (TSH) of the Small Bowel following Laparoscopy Despite Rectus Sheath Closure, Resulting in Subacute Bowel Obstruction in the Early Post-Operative Period: A Case Discussion and Review of Literature
Senadheera, DI, Jayasundara, DMCS and Jayawardane, IA
Article Type: Case Report and Literature Review | First Published: December 12, 2020
Laparoscopy is becoming the gold slandered of access to the abdomen and pelvis. However, it’s not without unique complications. Trocar site hernia is a rare but a serious complication which can cause diagnostic confusion, in the early post-operative period. It can be potentially life threatening with obstruction, strangulation, incarceration and finally perforation of the bowel, after a seemingly uncomplicated laparoscopy. First ever TSH, reported by “Fear in 1968”. Early studies described...
Open Access DOI:10.23937/2377-9004/1410185
Nagat Bettamer, Ream Langhe, Zahia Elghazal, Farag Ben Ali and Lamia Alkikhia
Article Type: Case Report | First Published: December 06, 2020
The authors present a rare case of vulval swelling in a 2-year period in a 35-year-old woman. The swelling was associated with mild vulval discomfort but no other symptoms. The tumour was removed surgically with no complications. Histopathology of the swelling confirmed vulval leiomyoma. Postoperative recovery was unremarkable and the woman was discharged on postoperative day 2. A 35-year-old patient presented to our department with a history of painless left vulval swelling of over a duration o...
Open Access DOI:10.23937/2377-9004/1410184
Ulipristal Acetate: Medical Management for Benign Metastasizing Leiomyoma?
Adina Schwartz, MD, Olivia Carpinello, MD and Alan DeCherney, MD
Article Type: Case Report | First Published: December 03, 2020
To describe the use of ulipristal acetate in an attempt to medically treat benign metastasizing leiomyoma (BML). Benign metastasizing leiomyoma (BML) is a rare disease characterized by smooth muscle tumors found outside of the uterus. Treatment options include surgery, embolization, and medical management. This case describes the use of ulipristal acetate in an attempt to medically manage an inoperable case of BML. A 40-year-old female presented with abdominal pain, urinary frequency, and decrea...
Open Access DOI:10.23937/2377-9004/1410183
Antenatal Management of Second Trimester Oligohydramnios and Evolving Abnormal Ultrasound Findings: Case Report
Daniel Roshan, MD, FACOG, FACS, Ellen Kolman, PA-C, Shira Plonka, MS CGC and Ilan Timor, MD, FACOG
Article Type: Case Report | First Published: December 03, 2020
Appropriate patient selection for prenatal intervention in the setting of abnormal antenatal ultrasound findings remains challenging. This case illustrates the course of a complicated pregnancy in a 35-year-old gravida 1 para 0 who presented to our Maternal-Fetal-Medicine clinic at 24.2 weeks gestation with fetal ascites, scalp edema, and oligohydramnios. Her first trimester ultrasound and genetic screening was normal. The patient was counseled that the observed findings carried a high chance fo...
Open Access DOI:10.23937/2377-9004/1410182
Opioid Consumption after Transversus Abdominis Plane Block in Abdominal Hysterectomy
Ashley S Moon, MD, Dorothy Wakefield, MS, Joann Petrini, PhD, MPH, Vaagn Andikyan, MD and Erin Panarelli, MD
Article Type: Original Research | First Published: November 19, 2020
Transversus abdominis plane (TAP) block is an important component of multimodal analgesia after abdominal hysterectomy to help with postoperative pain control. Our study evaluates 24-hour postoperative opioid consumption after TAP block in abdominal hysterectomy. Retrospective study of 174 women who underwent abdominal hysterectomy at a single institution. Statistical analyses compared demographic variables, compared opioid consumption and pain score distributions, assessed the association betwe...
Open Access DOI:10.23937/2377-9004/1410181
A Case Report of Spontaneous Pregnancy in a Mosaic Turner Syndrome Patient
Abdelrahman Yousif, Madeline Wheatley and Moustafa A Abuzeid
Article Type: Case Report | First Published: November 04, 2020
1 in every 2500 females is born with turner syndrome (TS), a result of chromosomal abnormalities of the X chromosome. A common symptom of this syndrome is infertility due to ovarian dysgenesis. This case report will detail a spontaneous pregnancy in a 22-year-old female Gravida 1 Para 0 (G1P0) patient with mosaic Turner syndrome. At 34 weeks 0 days, she presented for her prenatal appointment with a past medical history significant for mosaic Turner syndrome diagnosed in her teens after a diagnos...
Open Access DOI:10.23937/2377-9004/1410180
Meconium Peritonitis: In Utero Diagnosis of a Rare Clinical Entity and Postnatal Outcome
Sarita Agrawal, MD, FICOG, FIAMS, FCGP, Arpana Verma, MS, Sarita Rajbhar, MS, Pushpawati Thakur, MD, Loukya Kodumuri, MBBS and Swati Kumari, MS, FNB
Article Type: Case Report | First Published: October 23, 2020
Meconium peritonitis (MP) is a rare cause of non-immune hydrops with reported incidence of 1:35,000 live births. MP is defined as an aseptic localized or generalized peritonitis caused due intrauterine bowel perforation and extravasation of the meconium. Few causes which might result in perforation include Ileal atresia, intussusception, Hirschsprung’s disease, cystic fibrosis, volvulus, colonic atresia, Meckel diverticulitis and vascular insufficiency. Successful outcome with conservative man...
Open Access DOI:10.23937/2377-9004/1410178
Spontaneous Conception after Hysterosalpingography in an Infertile Woman with Bilateral Tubal Factors: A Case Report
Ayissi Grégory, Astrid Ndolo Kondo, Kasia Onana Yves Bertrand, Ebode Koa Vanessa, Azambou Kenteu Sandrine, Ngo Dingom Anne Madye and Essiben Felix
Article Type: Case Report | First Published: October 16, 2020
Hysterosalpingography (HSG) is an outpatient fluoroscopy procedure that evaluates the uterine cavity and fallopian tube patency. In some cases, HSG may have a therapeutic effect. We present the case of a 35-year-old HIV-positive woman with a 3-years-old history of secondary tubal infertility, a hysterosalpingogram revealing bilateral proximal tubal obstruction and presented later on with a 6-weeks pregnancy on ultrasound after HSG evaluation. Hysterosalpingography (HSG) is an inexpensive and wid...
Open Access DOI:10.23937/2377-9004/1410177
SARS-CoV-2 Infection in Pregnancy: A Case Report on the First Emergency Cesarean Section in Vietnam and Literature Review
Tran Dinh Vinh, Vu Van Long and Pham Chi Kong
Article Type: Case Report and Literature Review | First Published: October 12, 2020
We report the first case of a pregnant woman infected with SARS-CoV-2 having an emergency cesarean section in Vietnam. This is the 569th patient infected with SARS-CoV-2 in Vietnam and is one of the first two pregnant women infected with SARS-CoV-2 in Vietnam (along with patient number 495 who is 11 weeks pregnant). The patient has a history of treatment at Da Nang General Hospital (an outbreak in Da Nang City) due to urinary tract infection. The patient was discharged from the hospital on July ...
Open Access DOI:10.23937/2377-9004/1410176
Gynaecological Near-Miss from Meleney’s Gangrene Post- Abdominal Myomectomy: A Case Report
Babatunde Olaniyi ROSIJI, Omagbeitse Henry ABIYERE, Babatunde Ajayi OLOFINBIYI, Olalekan Oladipupo ROSIJI, Blessing Oluwatosin OLANREWAJU and Olakunle John AYELOJA
Article Type: Case Report | First Published: October 03, 2020
Necrotizing fasciitis is a severe, rare, potentially lethal soft tissue infection that develops in the scrotum and perineum, the abdominal wall or the extremities. It progresses rapidly and septic shock may ensue. When the anterior abdominal wall is involved it is referred to as Meleney's gangrene. It is seen as a serious complication of surgery which evolves rapidly and could carry a high mortality rate of 30-50%, approaching up to 90% in diabetic patients. It is a synergistic infection involvi...
Open Access DOI:10.23937/2377-9004/1410175
Value of Minimally Invasive Gynecologic Surgeon in Surgical Management of Endometriosis
Natasha Gupta, MD
Article Type: Short Commentary | First Published: October 01, 2020
The quality of endometriosis surgery performed by a Minimally Invasive Gynecologic Surgeon (MIGS) is significantly different from that of a general gynecologist. Their training offers them the experience to detect subtle endometriosis, excise deeply infiltrative endometriosis, manage extra pelvic endometriosis and restore normal anatomy in stage 4 endometriosis. They are able to preserve fertility in an endometriosis patient if patient desires fertility. They are also able to address or excise e...
Open Access DOI:10.23937/2377-9004/1410174
In Vitro Fertilization Treatment of a Patient with Primary Partial Empty Sella and Other Co-Factors
Tünde Herman, Péter Török, Antonio Simone Laganà and Attila Jakab
Article Type: Case Report | First Published: September 23, 2020
We report the case of a patient with primary empty sella, who had successful assisted reproductive treatment. The patient is a 28-years-old infertile female with primary amenorrhoea and hypogonadotropic hypogonadism. Serum FSH, LH, E2 indicated central anovulation, but the production of GH, ACTH, TSH and PRL were normal. Obesity and insulin resistance were present. Male partner had asthenozoo-teratospermia and hyperprolactinaemia. After three failed intrauterine inseminations, she was addressed ...
Open Access DOI:10.23937/2377-9004/1410173
Management of Complete Hydatidiform Mole with Co-existing Fetus
Kaitlin DiBartola, MD, Devin Smith, MD, Kara Rood, MD and David O'Malley, MD
Article Type: Case Report | First Published: September 21, 2020
Complete hydatidiform mole with co-existing fetus (CHMCF) is a rare obstetrical finding. These pregnancies pose a unique set of health concerns including hemorrhage, thyrotoxicosis, preeclampsia, and gestational trophoblastic neoplasia (GTN). In this report, we present a 34-year-old G5P1 presented at 6 weeks and 5 days with vaginal bleeding. Further follow-up revealed a complete hydatidiform mole with co-existing fetus in a patient who desired continuation of pregnancy. There is a lack of data a...
Open Access DOI:10.23937/2377-9004/1410172
Case Report: Pregnancy While Using an IUD
Elvin Piriyev and Thomas Römer
Article Type: Case Report | First Published: September 19, 2020
Intrauterine contraception, mostly in the form of copper IUD or hormone-releasing system, is a widely used method with a high level of contraceptive security. Despite high contraceptive efficiency, pregnancy can still occur. Pregnancy with a levonorgestrel-releasing intrauterine system (LNGIUS) in situ is very rare. Intracavitary pregnancy with an IUD can lead to a higher risk of infection and preterm birth. We present the case of a 28-year-old woman who was admitted to our hospital due to pregn...
Open Access DOI:10.23937/2377-9004/1410171
Uterine Arteriovenous Malformation after First Trimester Termination of Pregnancy in a Patient with Hereditary Haemorrhagic Telangiectasia
Nicola Strobelt, MD, Elena Osella, MD and Vittorio Aguggia, MD
Article Type: Case Report | First Published: September 13, 2020
Hereditary haemorrhagic teleangiectasia (HHT) is a rare autosomic dominant genetic disorder, characterised by epistaxis, cutaneous teleangiectasias, and arteriovenous malformations (AVMs) located mainly in lungs, gastrointestinal tract, liver, and central nervous system. We report a case of uterine arteriovenous malformation acquired after medical pregnancy interruption in a patient with HHT, discussing the atypical genetic setting and the strategy for the case management. Uterine arteriovenous ...
Open Access DOI:10.23937/2377-9004/1410170
The Contribution of Anthroposophic Medicament Bryophyllum to the Quality of Life of Patient with Diagnosis of Cavernoma during Prenatal Care: A Case Report
Maria Fernanda Zugliani, Anamaria da Silva Facina, MD, PhD, Regina Helena Wirgues Ramos, Daniel Pereira Götz, Jorge K Hosomi, MD, MS, Eliane CR Follador, MD, PhD and Mary Uchiyama Nakamura, MD, PhD
Article Type: Case Report | First Published: August 10, 2020
We present the successful prenatal and postpartum follow up of a pregnant woman with diagnosis of epilepsy due to brain cavernoma, and depression. A 26-years-old woman had been receiving anti-epileptic drugs (carbamazepine and clobazam) for nine years, which were suspended at risk of teratogenicity at 10 weeks’ pregnancy, when she started prenatal care. The diagnosis was made when she had her first seizure at 17-years-old, and the characteristic image of brain cavernoma was detected on MRI. Sh...
Open Access DOI:10.23937/2377-9004/1410169
Giant Hemorrhagic Ovarian Cyst with Torsion-Rare Case Report
Durga K, MD, Yasodha A and S Yuvarajan
Article Type: Case Report | First Published: July 23, 2020
Giant ovarian tumours are rare nowadays due to early recognition of these tumours in clinical practice. Management of these tumours depends on age of the patient, size of the mass and its histopathology. We are reporting a rare case of torsion of hemorrhagic ovarian cyst presented to us with acute abdomen. 22-year-old, unmarried girl came to our outpatient department with complaints of lower abdominal pain for 3 days. Patient was apparently normal before 3 days after which she developed lower ab...
Open Access DOI:10.23937/2377-9004/1410168
A Case of a 33-Week Pregnant Woman with COVID-19 and Term Birth
György Léhner, MD, Walter Krugluger, MD, Stephan W Aberle, MD, Lukas Weseslindtner, MD and Beda Hartmann, MD
Article Type: Case Report | First Published: July 17, 2020
In this case report, we present a pregnant woman diagnosed with COVID-19 at 33 weeks gestation and having a vaginal birth at term. The postpartum and neonatal courses were uncomplicated. Anti-SARS-CoV-2-IgG antibodies were detected in the neonate. A vaginal delivery in this case was safe with clinical diagnosis of COVID-19. To date, there are only limited data about the effect of novel coronavirus (SARS-CoV-2) infection on pregnancy, delivery and placental transfer of antibodies. According to re...
Open Access DOI:10.23937/2377-9004/1410167
Conservative Management of Endometrial Carcinoma and Precursor Lesions Preceding IVF Treatment: A Case Series
Huda Afaneh, MD, Ahmed SZ Moustafa, MD, Stephanie Leiva, MD, Youssef Youssef, MD, Ahmed Abdullah, MD, John Hebert, III, MD, FACOG and Mostafa Abuzeid, MD, FACOG, FRCOG
Article Type: Case Series | First Published: June 11, 2020
Endometrial cancer (EC) is the most common gynecological malignancy in developed countries with a lifetime risk of 3% for women living in the United States. Women younger than 45 years of age represent 7% of endometrial cancer cases. Type 1 endometrioid adenocarcinoma is the most common type. Endometrial intraepithelial neoplasia (EIN) is a precursor lesion that carries a risk of concomitant invasive disease in up to 40% of patients. Risk factors for type 1 endometrial cancer and EIN include uno...
Open Access DOI:10.23937/2377-9004/1410166
A Rare Case: Nodular Adenomyosis Can Deceive Cornual Ectopic Pregnancy
Elvin Piriyev, Walter Mellin and Thomas Romer
Article Type: Case Report | First Published: June 03, 2020
Adenomyosis refers to the occurrence of ectopic endometrial glands and the surrounding stroma within the myometrium. A distinction is made between diffuse and focal forms (rare nodular forms and an adenomyoma). Ectopic pregnancy (EUG) occurs in about 1.5 to 2.0% of pregnancies and can be a life-threatening event. 2% of all EUG are cornual/intramural ectopic pregnancy. We present the case of a 33-year-old women (GII/PI) who complained about vaginal bleeding in the 6th week of pregnancy. The next ...
Open Access DOI:10.23937/2377-9004/1410165
A Rare Presentation of Herlyn Werner Wunderlich Disease in Young Female
Nicola Zampieri, MD, PhD
Article Type: Case Report | First Published: May 08, 2020
Herlyn-Werner-Wunderlich syndrome is a rare urogenital anomaly consisted of renal agenesia, uterovaginal duplication and ipsilateral blind hemivagina. Usually it presents some months after menarche with pelvic pain, acute abdomen, intermenstrual bleeding. A 13 year premenarchal female was transferred to our unit for acute abdomen and MR findings of left renal agenesis, blind hemivagina distended by ematic material, complete uterus duplication, dilated tuba and left ovarian mass with torsion. A d...
Open Access DOI:10.23937/2377-9004/1410164
Cangrelor in an Obstetric Patient Undergoing Cesarean Section on Dual Antiplatelet Therapy after Cerebral Stent Placement: A Case Report
Lauren Carlos, MD, Stephanie Paolini, MD, Christine Hawkes, MD, Janet FR Waters, MD, Ashutosh Jadhav, MD, PhD and Jonathan H Waters, MD
Article Type: Case Report | First Published: April 30, 2020
In this case, a 34-year-old woman G1P0 at 31 weeks gestation required intracranial stenting for an acute ischemic stroke. She was placed on aspirin and clopidogrel to prevent stent occlusion. The patient wished to undergo a cesarean delivery. Patients on dual antiplatelet therapy are at high risk of hemorrhage. Five days prior to the surgery, clopidogrel was replaced with cangrelor, a short-acting, reversible P2Y12 receptor inhibitor which was turned off at anesthesia induction. Surgery and the ...
Open Access DOI:10.23937/2377-9004/1410161
Mesenteric Venous Thrombosis Causing Acute Mesenteric Ischemia in the First Trimester of Pregnancy
Youssef M Zohdy and Ziad M Ahmed
Article Type: Case Report | First Published: April 03, 2020
Acute mesenteric ischemia is a rare complication of thromboembolic diseases in the mesenteric vessels, which was noted to occur due to the hypercoagulable circulation associated with pregnancy. Additionally, the early detection and treatment of such disease prevents further deterioration of the mother’s condition, thus ensuring a favorable outcome for both the mother and the fetus. This paper presents a case report of acute mesenteric ischemia in a 9 weeks pregnant female, which was diagnosed ...
Open Access DOI:10.23937/2377-9004/1410160
A Case of Uterine Arteriovenous Malformation with Retained Products of Conception, Presenting as Secondary Post-Partum Haemorrhage
OG Abutu, Bivas Biswas, Onnig Tamizian and AS Tirlapur
Article Type: Case Report | First Published: March 24, 2020
Uterine arteriovenous malformation (AVM) is defined as the rare occurrence of an abnormal and nonfunctional connection between uterine arteries and veins. Bleeding per vaginum is the typical presentation with potential for acute onset, life threatening haemorrhage. Investigations including ultrasound with or without doppler, magnetic resonance imaging [MRI] and angiography are often used to aid in the diagnosis. Management of uterine AVMs depend on the hemodynamic status of the patient, size and...
Open Access DOI:10.23937/2377-9004/1410163
Urinary Retention in The Case of a Retroverted Uterus in Pregnancy
Camille A Clare, MD, MPH
Article Type: Case Report | First Published: April 08, 2020
Acute urinary retention in patients with retroverted uteri is a rare, obstetrical emergency, and requires immediate intervention. If not treated, it may lead to serious maternal and/or fetal complications. This manuscript describes the case of a 35-year-old female who presents with lower abdominal pain and urinary hesitancy. Physical examination noted a palpable urinary bladder, which was also distended on pelvic ultrasound. Obstetrical ultrasound noted a viable intrauterine pregnancy. The patie...
Open Access DOI:10.23937/2377-9004/1410162
Surgical Management of a Juvenile Cystic Adenomyoma: A Unique Presentation of Adenomyosis
Huda Afaneh, MD, Karen Moses, MD, Omari Young, MD and Mostafa Abuzeid, MD, FACOG, FRCOG
Article Type: Case Report | First Published: April 03, 2020
Endometriosis is characterized by the presence of endometrial glands and stroma in ectopic locations within the peritoneal cavity. More commonly, the lesions can be found on areas such as the cul-de-sac and other pelvic parietal surfaces. Endometrial glands and stroma infiltrating the myometrium characterizes Adenomyosis. Adenomyosis is usually characterized by diffuse foci of endometrial glands scattered throughout the myometrium. Meanwhile, a less common type of adenomyosis, in which the lesio...
Open Access DOI:10.23937/2377-9004/1410159
Immature Fetiform Teratoma: An Unexpected Cause of Retroperitoneal Mass
Fernando Vazquez Rueda, Maria Rosa Ibarra Rodriguez, Francisco Javier Murcia Pascual, Sharmila Devi Ramnarine Sanchez, Sandra Rocio Wiesner Torres and Rosa Maria Paredes Esteban
Article Type: Case Report | First Published: February 06, 2020
A 5-month-old with normal prenatal checks, with a right permeable hydrocele antecedent, a non-painful and well-delimited mass, which occupied the entire right hemi abdomen, was incidentally detected. Ultrasound and abdominal CT show a retroperitoneal lesion that occupied the entire abdominal cavity, with the presence of fat bulbs and calcifications, which did not depend on any organic structure. Tumor markers were normal. Laparotomy was performed with complete exéresis of tumour. Histopathologi...
Open Access DOI:10.23937/2377-9004/1410158
Uterine Rupture Following Misoprostol Induction of Labour at 36 Weeks Gestation in an Unscarred Uterus
Ansong G, Sebuabe SA and Afrani AK
Article Type: Case Report | First Published: January 30, 2020
Case report of a 33-year-old G5P3+1SA diagnosed with an intrauterine foetal death at 36 weeks gestation and induction of labour started with 400 ug of misoprostol vaginally, which was complicated by a uterine rupture with subsequent referral and management in our facility. Intra-operative findings during laparotomy revealed uterine rupture with a macerated still birth intra-abdominally and moderate hemoperitoneum. Uterine rupture in an unscarred uterus following unsuccessful induction is an adve...
Open Access DOI:10.23937/2377-9004/1410157
A Rare Form of Dermoid Cyst: A Fetiform Teratoma
Erciyestepe SG, Turan H and Kahramanoglu I
Article Type: Case Report | First Published: January 24, 2020
Thirty three-years-old patient presented with abdominal distention and intermittent abdominal pain. She gave vaginal birth 2 times; last one three years ago. She didn’t have history of any abdominal operation, family history, or comorbidities. Her menstrual periods were regular. Review of the systems were unremarkable. In the pelvic examination, a 10 cm abdominal mass palpated which deviated to the left side. The pelvic mass had a soft consistency and free mobility. In the ultrasonography, 80*...
Open Access DOI:10.23937/2377-9004/1410156
Herlyn-Werner-Wunderlich Syndrome: A Rare Cause of Acute Abdomen in Adolescent Girls
Maher AlZaiem, MD, CU, ABPS, Abdulnaser Ali Alatili, MD, Ahmed Alawi, SBPS and Fadi Zaiem, MBBS
Article Type: Case Report | First Published: December 30, 2019
Herlyn-Werner-Wunderlich syndrome (HWHS) is a rare developmental anomaly of Mullerian ducts, characterized by the presence of a uterus didelphys with longitudinal vaginal septum obstructing the hemivagina and the presence of ipsilateral renal agenesis. It is a very rare syndrome with only a few cases that have been reported. We describe, In this report, the clinical presentation and the successful surgical management of an 11-year-old girl who presented with acute lower abdominal pain and palpab...
Open Access DOI:10.23937/2377-9004/1410155
Erector Spinae Plane Block for Peripartum Analgesia in a Patient with Tarlov Cysts
LT Scott B Hughey, MD/MBA, MC(FS), USN, LT Jacob H Cole, MD, MC, USN, LCDR Thomas F Olson, MD, MC(FMF), USN and LCDR Victor A Rivera, MD, MC(FS), USN
Article Type: Case Report | First Published: December 21, 2019
Tarlov cysts are sacral perineural cysts which occur in up to 4.6% of the population. Neuraxial anesthesia is relatively contraindicated in these patients. Similarly, many of these patients have chronic pain from the cysts, often requiring chronic opioid use. Pain during labor may be difficult to control in these patients due to concerns regarding neuraxial analgesia and submaximal benefit from systemic remifentanil infusions. The Erector Spinae Plane (ESP) Block has recently been described as a...
Open Access DOI:10.23937/2377-9004/1410154
Endovascular Management of Refractory Puerperal Hematomas: A Case Report and Review of the Literature
Simon Bradette, MD, FRCPC, Melissa Marien, MD, PGY-3, Melanie Rousseau, MD, FRCPC, Mathieu Beland, MD, FRCPC and Catherine Lalonde, MD, FRCPC
Article Type: Case Report | First Published: November 06, 2019
Pelvic hematomas can be a serious complication of vaginal delivery. They can be associated with significant morbidity related to blood loss, infection, surgery and blood product transfusion. Reported incidence varies from 1/300 to 1/1500. Operative vaginal delivery and episiotomy are among the most common risk factors associated with puerperal hematomas, but they may also occur in the absence of laceration of the surrounding tissue. They are classified as vulvar, vaginal, vulvovaginal or retrope...
Open Access DOI:10.23937/2377-9004/1410153
Refractory Hyperemesis Gravidarum in a Patient with Type 1 Diabetes Treated with Laparoscopically Assisted Feeding Jejunostomy Tube Placement
Melissa Chu Lam, MD, Briana Baxter, MD, Farrah Naz Hussain, MD, Kristina Martimucci Feldman, MD and Barak Rosenn, MD
Article Type: Case Report | First Published: November 04, 2019
Severe Hyperemesis gravidarum (HG) is a debilitating condition that affects less than 1% of pregnant women. Management of HG is further complicated in women with type 1 diabetes due to oscillations between hypo and hyperglycemia, often exacerbated by the presence of gastroparesis. We report a 25-year-old G1P0 with longstanding uncontrolled type 1 diabetes mellitus (HbA1C 10.5%), who presented to our service multiple times with hyperemesis and ketosis. On each of these admissions, she was diagnos...
Open Access DOI:10.23937/2377-9004/1410152
Robotic Radiosurgery to a Patient with Locally Advanced Cervical Cancer and Uterus Didelphys - A Case Report and Review of Literature
Janis Morgenthaler, Christhardt Kohler and Simone Marnitz
Article Type: Case Report | First Published: October 05, 2019
Consolidation brachytherapy is a critical treatment component for locally advanced cervical cancer. The use of alternatives (linac based stereotactic radiosurgery (SRS) or external beam (EBRT) boosts) on linacs compromise oncologic results in cervical cancer patients. Our patient, a 32-year old woman with a 5 cm FIGO IIB cervical cancer, had a uterus Didelphys and was therefore not suitable for intracervical brachytherapy. Instead, she received a brachytherapy emulating robotic radiosurgery boos...
Open Access DOI:10.23937/2377-9004/1410151
Isolated Fallopian Tube Torsion: A Rare Cause of Acute Abdominal Pain
Wael Hosni and Carl-Michael Schmidt
Article Type: Case Report | First Published: August 31, 2019
Isolated torsion of the fallopian tube without epsilateral ovarian involvement is a rare cause of acute lower abdominal pain in females. The clinical presentation of tubal torsion is nonspecific and is therefore a challenge for the clinician to recognize. A definitive diagnosis can rarely be made prior to surgery. An early diagnosis may help to preserve the fallopian tube. We report a case of isolated fallopian tube torsion in a young female patient. The patient’s presentation raised clinical ...
Open Access DOI:10.23937/2377-9004/1410150
An Unusual Case of Acute Complete Urinary Incontinence 20 Days after Pelvic Floor Surgery and Tension-Free Vaginal Tape Insertion 20 Days after Pelvic Floor Surgery and Tension-Free Vaginal Tape Insertion
Nicole Keller, Seraina Schmid and Beatrix Haemmerle
Article Type: Case Report | First Published: August 05, 2019
An 81-year-old woman presented herself with disturbing stress urinary incontinence and symptomatic pelvic organ prolapse. 30 years before she had had an abdominal hysterectomy and presumably a colposuspension. To repair the symptomatic pelvic floor disorder the patient needed an anterior and posterior colporrhaphy, vaginal repair of enterocele and anterior rectocele. Additionally, a tension-free midurethral sling (retropubic tension-free vaginal tape) was implanted because of stress urinary inco...
Open Access DOI:10.23937/2377-9004/1410149
Silver Russel Syndrome and Pregnancy
Juliana Barroso Zimmermmann, Adrianne Maria Berno de Rezende Duarte, Alexander Cangussu Silva, Patrícia de Oliveira Lima, Sophia Helena Batalha, Caroline Souza e Silva, Isadora Marinho de Sousa Bechtlufft, Analu Brito Mendes, Fernanda Coelho Ataydes Seabra, Júlia Alcântara Costa, Ana Clara Furtado Andreatta, Victória da Silva Coelho, Júlia Machado Azevedo de Freitas, Jorge Silveira Júnior, Isabela Rufini Gonçalves, Clarissa Rocha Panconi and André Luiz J
Article Type: Case Report | First Published: May 27, 2019
Silver-Russell syndrome is characterized by decreased intrauterine and postnatal growth, facial dysmorphia (triangular face), clinodactyly of the fifth finger, eating problems and body asymmetry, with a frequency of 1:50,000 to 1:100,000 live births. There are reports of rare familial cases with dominant autosomal, recessive autosomal and/or linked to the X and also of unknown etiology. ...
Open Access DOI:10.23937/2377-9004/1410148
Serum Transaminases Elevations to Predict Adverse Outcomes of Preeclampsia
Elkhoudri N, Fatima Zahra Marhoume, Amor H and Baali A
Article Type: Research Article | First Published: May 27, 2019
Eclampsia is characterized clinically by hypertension, edema, proteinuria, and seizures in women during the second half of pregnancy or in the immediate postpartum period. The pathophysiology remains unclear. One proposed mechanism is that cerebral vasospasm induced by severe hypertension results in ischemia and consequent cytotoxic edema. This is supported by angiographic findings of diffuse or focal vasospasm and by infarctions in some patients....
Open Access DOI:10.23937/2377-9004/1410147
Prognostic Factors for Secondary Cytoreductive Surgery in Recurrent Ovarian Cancer
Alice Savescu, IrinaBalescu, and Nicolae Bacalbasa
Article Type: Review Article | First Published: May 27, 2019
Ovarian cancer is an aggressive and lethal gynaecologic malignant disease with high capacity of relapse even if complete cytoreductive surgery is performed at the moment of the initial diagnosis. Once the relapses occur large studies focused on the subject of the best therapeutic protocol in order to achieve a good control of the disease. This is a literature review of the studies focused on this topic....
Open Access DOI:10.23937/2377-9004/1410146
Management of Fetal Supraventricular Tachycardia: Three Cases at a Single Institution
Rahel Ghenbot, MD, Veronica Gonzalez-Brown, MD and Kara Markham, MD
Article Type: Case Report | First Published: May 18, 2019
Fetal tachycardia complicates 1-2% of pregnancies, and a large percentage of these arrhythmias are supraventricular. Sustained fetal tachycardia can have serious complications for the fetus, including cardiovascular failure, nonimmune fetal hydrops, and fetal death. Management of fetal tachycardia depends on multiple factors. Here we present three different cases of fetal supraventricular tachycardia (SVT) and their management at a single institution....
Open Access DOI:10.23937/2377-9004/1410145
Uterine Leiomyoma with Lung Metastases Stump Tumour
Martin N, Escobar A, Varela A, Guillem E and Cortes-Funes H
Article Type: Case Report | First Published: April 24, 2019
We present one clinical case of a 41-year-old, female Russian origin patient, with lung nodules suggestive of metastases, with no primary tumor found, referred for study and treatment in our Oncology Department. After a deep analysis of the case, reviewed the literature and result of the pathology of biopsy from lung lesions, the final diagnosis reached was: Benign muscle tumors of Gynecological origin, with the capacity for produce distant metastasis compatible with STUMP Tumor (Metastatic leio...
Open Access DOI:10.23937/2377-9004/1410144
A Rare Case of Large Uterine Myoma in an Antenatal Women with Situs Inversus: A Case Report
Harsharan Kaur and Naina Kumar
Article Type: Case Report | First Published: April 15, 2019
Leiomyomas or fibroids are the most common benign tumor of uterus and it often increases in size during pregnancy. Its incidence in pregnancy is approximately 1.5-2% and is associated with increased risk of complication during pregnancy including abortions, preterm labor, red degeneration, malpresentations, increased cesarean section rates, postpartum hemorrhage. We hereby, discuss a case of large multi-lobed uterine fibroid complicating the second trimester of pregnancy. Our patient presented w...
Open Access DOI:10.23937/2377-9004/1410143
A Large Uterine Leiomyoma with Hypertrophied Omental Vessels: A Case Report
Ayse Nur Aksoy, Ebru Bulut Erdem, Gülsah Tanas Sarıkas and Elçin Telli
Article Type: Case Report | First Published: March 29, 2019
Uterine leiomyomas are the most common solid benign uterine neoplasms that arise from the overgrowth of smooth muscle and connective tissue in the uterus. It is estimated that 20-40% of women of reproductive age have uterine leiomyoma; the prevalence increases during the reproductive age and decreases after menopause. Uterine leiomyomas have been classified according to their location: Submucosal, intramural, subserosal. While subserosal uterine leiomyomas are usually asymptomatic; intramural an...
Open Access DOI:10.23937/2377-9004/1410142
Incarcerated Retroverted Uterus Manually Replaced in 24 Week Pregnancy
Lucy May, Susan Rutter, E H Whitby and Adam Temple
Article Type: Case Report | First Published: February 28, 2019
An incarcerated uterus is a rare obstetric complication, with a reported incidence of 1 in 3000 pregnancies. It occurs when a retroverted uterus does not resolve beyond mid-gestation and the uterine corpus becomes confined in the hollow of the sacrum. This causes the cervix to become displaced above or against the pubic symphysis. Retroversion of the uterus occurs in 15% of pregnancies and is considered a normal anatomical variation and usually resolves to an anteverted position by 14-16 weeks g...
Open Access DOI:10.23937/2377-9004/1410141
The Clinical Differences on 2:4 Finger Ratios of the Hirsute Women
Raziye Desdicioglu, Fatma Betul Erdemli, Selma Calıskan, Kadir Desdicioglu and Ayse Filiz Yavuz
Article Type: ORIGINAL ARTICLE | First Published: February 27, 2019
We aimed to research whether there was a difference in terms of the 2:4 finger ratio between women with hirsutism and healthy women without hirsutism and the correlation between degree of hirsutism and 2:4 finger ratios and clinically evaluated our results. Our study included 144 voluntary women (control group: 51, study group: 93) with ages from 18 to 38 years. The hirsutism level of patients was assessed using the Ferriman-Gallway scale with points given from 0 to 4 in 9 body regions. All pati...
Open Access DOI:10.23937/2377-9004/1410140
Hyperextension of the Fetal Neck
CR Elizalde, P Dieste, J Fernandez, V Fernadnez and C Zulueta-Santos
Article Type: CASE REPORT | First Published: February 22, 2019
The purpose of this study was to review the current challenges that the diagnosis and clinical management of hyperextension of the fetal neck represent and to describe the clinical significance and differential diagnosis of this entity, detected by ultrasound prior to the onset of labour. A case of hyperextension the fetal neck is presented. The key points in the diagnosis and management of fetuses with these sonographic finding are reviewed. Hyperextension of the fetal neck is a sonographic fin...
Open Access DOI:10.23937/2377-9004/1410139
Post-partum Polymorphic Eruption of Pregnancy
Brandao P, Portela-Carvalho AS, Melo A and Leite I
Article Type: Case Report | First Published: December 22, 2018
Polymorphic Eruption of Pregnancy, also known as Pruritic Urticarial Papules and Plaques of Pregnancy, is a common benign dermatosis of pregnancy related to stretching of the abdominal wall, frequent misdiagnosed with an allergic reaction. It usually appears during late third trimester and resolves within few days or weeks or after deliver. The authors present a case of Polymorphic Eruption of Pregnancy with its typical features appearing for the first time 5 days after delivery. The patient had...
Open Access DOI:10.23937/2377-9004/1410138
Evaluation of the Symptoms of Fibromyalgia in Premenopausal Women with Urinary Incontinence
Keziban Dogan, Filiz Yılmaz Aydın and Meltem Vural
Article Type: Research Article | First Published: November 30, 2018
Both urinary incontinence (UI) and fibromyalgia symptoms affect the physical function of women and lead to negative effects on the quality of life and emotional status. Our aim is to identify the prevalence of symptoms of fibromyalgia (FM) in women with UI and the relationships of FM with subtypes of UI. UI was diagnosed based on clinical histories, gynecologic examinations and urodynamic investigation results. FM was diagnosed according to the 2010 American Community of Rheumatology criteria......
Open Access DOI:10.23937/2377-9004/1410137
Non-Painful Out of Pill Membranous Dysmenorrhoea
Brandao P, Portela-Carvalho AS and Oliveira C
Article Type: Case Report | First Published: November 29, 2018
Membranous Dysmenorrhoea is defined as sudden sloughing of thickened endometrium as a whole with the shape of the uterine cavity, which may be associated with severe abdominal cramping. Although not rare, there are few cases described. It's more common in young females who were on either combined or progesterone only contraceptive pill, causing the decidualization of the endometrium. Due to its similarities to a gestational sac, miscarriage is the main differential diagnosis....
Open Access DOI:10.23937/2377-9004/1410136
Risk Factors Associated with Preterm Birth in a Brazilian Maternal and Child Health Hospital
Bianca Karenina Brito de Medeiros, Maria da Conceicao Cornetta, Janaina de Oliveira Crispim and Ricardo Ney Cobucci
Article Type: Research Article | First Published: November 19, 2018
This population-based case-control study aims to verify the risk factors associated with preterm birth (PTB) in a maternity school. The cases were newborns with a gestational age greater than or equal to 22 weeks and less than 37 weeks (birth weight greater than or equal to 500 g), and controls were those born with gestational age equal to or greater than 37 weeks gestation. Data are recorded in the Live Birth Information System of 3,915 births at the Januário Cicco Maternity School in the year...
Open Access DOI:10.23937/2377-9004/1410135
Vulvar Neoplasia in Cameroon, West Africa: Diagnostic Challenges
Simon M Manga, Rosanna F DeMarco, Florence Manjuh, Zacharie Sando and Edith R Welty
Article Type: Case Report | First Published: November 15, 2018
Disorders of the vulva have characteristically received less attention than disorders of the cervix and other reproductive organs. There are a number of challenges in diagnosing vulvar neoplasia (pre-invasive and invasive vulvar disease) in Cameroon and other low- and middle-income countries (LMICs). This is primarily because the early signs and symptoms of vulvar neoplasia are non-specific and are predominantly characterized by pruritus vulvae, which can easily be mistaken for vulvar candidiasi...
Open Access DOI:10.23937/2377-9004/1410134
Accurate Diagnosed by a Contrast-Enhanced Abdominal Computed Tomography (CT) for a Ruptured Large Tubal Pregnancy Mimicking Abdominal Pregnancy
Kun-Ta Ho, Jen-Yu Wen and Ming-Ping Wu
Article Type: Case Report | First Published: October 31, 2018
Abdominal ectopic pregnancy is a more complicated and severe situation, as compared with tubal pregnancy. Accurate differential diagnosis between abdominal and tubal pregnancy is important before the choice of laparoscopic approach. We presented the use of contrast-enhanced computed tomography (CT) to diagnose an unusual presentation of large tubal pregnancy mimicking abdominal pregnancy. A 24-year-old woman presented to emergency room (ER) with acute abdominal pain. Transabdominal ultrasound de...
Open Access DOI:10.23937/2377-9004/1410133
Endometrial and Colorectal Synchronous Cancer: A Case Report
Jose Antonio Perez Alvarez, Beatriz Contreras Gonzalez, Alfonso Angel Quesada Lopez-Fe, Dacil Judit Preckler Pena and Cristina Luisa Sanchez-Pinto Hernandez
Article Type: Case Report | First Published: October 25, 2018
Synchronous detection of different types of cancer at the pelvic level is a rare finding. Due to its low incidence, the actual knowledge of this disease is difficult since it is based on articles published on small series of cases. We present the clinical, surgical, and anatomopathological findings of a patient with a synchronous endometrial cancer with a colorectal cancer. Synchronous detection of different types of pelvic cancer in women is a rare finding in gynecologic oncology. Synchronous p...
Open Access DOI:10.23937/2377-9004/1410132
Cesarean Section in a Parturient with Pseudocholinesterase Deficiency Suspected by Preoperative Interview and Immune Thrombocytopenic Purpura
A Jlali, W Ben Moussa, M Gara, O Ammar, M Mehdi and L Grati
Article Type: Case Report | First Published: October 24, 2018
The preoperative evaluation of a patient for anesthesia is the cornerstone for perioperative management plans. The following case report details the importance of medical interview in a parturient with suspected pseudocholinesterase deficiency and documented immune thrombocytopenic purpura, and shows that anesthetic complications can be avoided by a rigorous preoperative anamnesis. Pseudocholinesterase (PChE) deficiency is an inherited or acquired condition in which the metabolism of succinylcho...
Open Access DOI:10.23937/2377-9004/1410131
Uterus-Sparing Treatment Options for the Management of Fibroids
Alessandro Napoli, Roberto Scipione, Hans-Peter Erasmus, Cristina Marrocchio, Susan Dababou, Fabrizio Andrani, Carola Palla, Michele Anzidei, Federica Ciolina, Lucia Manganaro, Delia Savone, Ludovico Muzii, Francesco Pecorini and Carlo Catalano
Article Type: Original Article | First Published: August 22, 2018
Currently, different treatment options are available in the management of uterine fibroids: Medical therapy aims at relieving symptoms, while semi-invasive or non-invasive procedures aim to treat symptoms and eventually to reduce the fibroids' size. A wide spectrum of treatments may be confusing to implement correctly, and the gynecologist should be familiar with the features of each procedure, to provide a personalized therapy....
Open Access DOI:10.23937/2377-9004/1410130
Primary Breast and Lung Cancer - Case Report
Rodrigo Dias Nunes, Adriana Magalhaes de Oliveira Freitas and Djulie Anne de Lemos Zanatta
Article Type: Clinical Case | First Published: August 10, 2018
A case review of a Caucasian 35-year-old female patient with no family history, diagnosed with primary breast cancer, and later finding lesions on the right lung. After image exams on the lungs and research, what was expected to be a result of a metastasis, was in fact a primary adenocarcinoma....
Open Access DOI:10.23937/2377-9004/1410129
A Case of Intra-Operative Anaphylaxis to Patent Blue Dye during Sentinel Lymph Node Biopsy
A Jlali, M Gara, M Mehdi and LGrati
Article Type: Case Report | First Published: August 02, 2018
Patent Blue Violet dye is commonly used for selective localization of the lymphatic system before sentinel lymph node biopsy. This procedure is routinely recommended for staging the axilla in early breast cancer. However, it has long been recognized that such dye is associated with anaphylaxis. Here, we present a case of an intraoperative grade 2 anaphylaxis which commenced 20 minutes following the subcutaneous periareolar injection of patent blue for sentinel lymph node detection during segment...
Open Access DOI:10.23937/2377-9004/1410128
A Case of Intra-Abdominal Desmoplastic Small Round Cell Tumor in a Young Girl Patient
Houda Fagouri, Mounia Ziyadi, Abdellahi Ibrahim, Ali Osman, Abdelah Babahabib, Mohamed Oukabli, Jaouad Kouach, Driss Rahali Moussaoui and Mohamed Dehayni
Article Type: Case Report | First Published: July 30, 2018
Desmoplastic small round cell tumor (DSRCT) is a rare and highly aggressive mesenchymal tumor; fewer than 200 cases have been reported in the literature. DSRCT mainly develops in adolescent and young adults with a strong male predominance; the male to female ratio is 4:1. Among female, it appears more precociously in the form of a pelvic mass, an abdominal distension or a high rate of Ca125. Its diagnosis is anatomopathological. The tumor typically develops in the abdominal cavity, invading the ...
Open Access DOI:10.23937/2377-9004/1410127
High Grade Uterine Sarcoma with Concurrent Metastatic Adenocarcinoma to the Uterus: A Case Report
Luke King, Radhika P Gogoi, Christopher Hummel, Zongming Chen and Ashlee Smith
Article Type: Case Report | First Published: July 12, 2018
A 59-year-old G1P1001 with a past medical history of hypertension, benign thyroid nodules, class III obesity (body mass index 35.02 kg/m2) and appendectomy with colonic resection due to intussusception as a child, presented for gynecologic consultation for a large uterine mass found on transvaginal ultrasound following a 2-month history of lower abdominal pain, vaginal bleeding, and malodorous vaginal discharge....
Open Access DOI:10.23937/2377-9004/1410126
Effect of N-Acetyl Cysteine Supplementation on Blood Lead Levels in Pregnant Women Suffering from Pre-Eclampsia
Shimaa M Motawei, Hossam E Gouda and Adel M El-Mansoury
Article Type: Original Article | First Published: June 09, 2018
Lead toxicity is still a prevalent public health problem in both developed and developing countries. While, the developed countries have largely succeeded to decrease the severity of this problem, developing countries still suffer from the burden of this health hazard and many sources of lead exposure still exist in these countries....
Open Access DOI:10.23937/2377-9004/1410125
An Atypical Presentation of Extraovarian Endometrioma
Alexander Berger, Nora Ward Graham, Crystal Berry-Roberts and William Schlaff
Article Type: case Presentation | First Published: May 30, 2018
Patients with endometriomas typically present with an intraovarian mass, often associated with multiple foci of extraovarian lesions. An isolated extraovarian endometrioma is rare and represents a challenging diagnostic dilemma....
Open Access DOI:10.23937/2377-9004/1410124
Early Pregnancy Loss: A Management Guide
Paul R Brezina
Article Type: Review Article | First Published: May 30, 2018
One of the most difficult aspects of reproductive medicine is the management of recurrent pregnancy loss. Recurrent pregnancy loss is one of the most emotionally devastating challenges facing couples who want to grow their family. For many couples, risk factors that increase the chances of experiencing a loss can be identified and treated. For other couples, however, a definitive cause is never identified....
Open Access DOI:10.23937/2377-9004/1410123
A Rare Case of Langerhans Cell Histiocytosis
Francesca Letizia Vellucci, Cristina Regini, Alice Cannoni, Cinzia Orlandini, Sandro Razzi, Rosa Santopietro, Felice Petraglia and Stefano Luisi
Article Type: Case Report | First Published: May 25, 2018
A 49-years-old nulliparous woman came to our attention reporting pain and discomfort in the vagina as well as an important dyspareunia, which prevented a normal sex life by a few months. The gynecological examination showed a small paraurethral lesion easily bleeding and a small sub urethral ulcerated lesion. A biopsy specimen of vagina reported localization of Langerhans cell histiocytosis (LCH)....
Open Access DOI:10.23937/2377-9004/1410122
High Grade Endometrial Stromal Sarcoma with Osteoclast-like Giant Cells: A Unique Subtype of a Rare Tumor
David Matthew Saulino, Noah Reilly, Bihong Zhao and Songlin Zhang
Article Type: case Presentation | First Published: May 23, 2018
Osteoclast-like giant cells have been reported in variety of different tumor types including breast carcinoma, pancreatic carcinoma, ovary tumor, uterine leiomyosarcoma, hepatocellular carcinoma, renal cell carcinoma. To the best of our knowledge, there are only two previous case reports in the literature showing endometrial stromal sarcoma with osteoclast-like giant cells. Endometrial stromal sarcoma is a rare uterine malignant neoplasm and includes low grade and high grade types....
Open Access DOI:10.23937/2377-9004/1410121
Adenomyosis in an 18-Year-Old Adolescent: A Case Report
Iaponira da Silva Vidal, Lilian Santos Soares, Cassio Aurelio Dutra, Mara Juliane Jovino, Ana Katherine Goncalves and Ricardo Ney Cobucci
Article Type: Case Report | First Published: March 31, 2018
Adenomyosis is a rare cause of chronic pelvic pain or severe dysmenorrhea that presents in the adolescent population. Here we describe an 18-year-old nulliparous woman who presented with a history of severe and worsening dysmenorrhea with cramps and increased menstrual flow since the menarche occurred 4-years-ago. A magnetic resonance imaging (MRI) described a poorly defined junctional zone of the endometrium, suggestive of adenomyosis, associated with the discrete heterogeneity of the adjacent ...
Open Access DOI:10.23937/2377-9004/1410120
Hot Flushes in a 15-Year-Old Girl Post Treatment of Bilateral Ovarian Dysgerminoma: A Case Report
Iaponira da Silva Vidal, Lilian Santos Soares, Karen Beatriz Gurgel, Ana Katherine Goncalves and Ricardo Ney Cobucci
Article Type: Case Report | First Published: March 29, 2018
Ovarian tumors in adolescents are a medical challenge due to their rarity. The aim is to describe a case of adnexal disease in a girl with hot flushes after treatment. A 15-year-old girl presented a history of menstrual delay and progressive increase of abdominal volume. Initially, clinical suspicion was for pregnancy, but after abdominal magnetic resonance imaging, a solid-cystic abdominopelvic mass was revealed. She underwent laparotomy and pathologic evaluation revealed a bilateral ovarian dy...
Open Access DOI:10.23937/2377-9004/1410119
Splenosis Mimicking Peritoneal Implants in a Female with Ovarian Cystic Masses: A Case Report
Nancy Boniel, Amit Mayer, Alex Rabinovich, Mihai Meirovitz and Alla Khashper
Article Type: Case Report | First Published: March 19, 2018
A case of large bilateral cystic ovarian masses is reported. Initial imaging, including ultrasound (US) and computed tomography (CT), showed a large right ovarian cystic tumor, a smaller multicystic left ovarian tumor and multiple solid peritoneal implants suspicious for metastases. Due to a history of remote post-traumatic splenectomy, the presence of bilateral benign ovarian cystic tumors in combination with peritoneal splenosis was considered....
Open Access DOI:10.23937/2377-9004/1410118
Case of Outpatient Pregnancy Prolongation at Premature Rupture of Membranes before Reaching the Viability Term
YE Dobrokhotova, AS Olenev, PA Kuzetsov, LS Djokhadze and KI Konstantinova
Article Type: Case Report | First Published: February 16, 2018
Premature rupture of membranes is not losing its topicality, as one third of all the premature deliveries starts with the discharge of the amniotic fluid. Despite the fact that the treatment tactics is represented in the normative documents, the world literature describes cases of the outpatient management of patients. The given article describes the case of a successful pregnancy completion as a result of outpatient management, which is considered to be an acceptable option in the case of the p...
Open Access DOI:10.23937/2377-9004/1410117
Ovarian Granulosa Cell Tumor: A Clinicopathological Series
Mark R Brincat, David Pisani, Donika Metaraku, Rachel Micallef, Yves Muscat Baron, Eleanor Borg, Annelise Aquilina, James Degaetano and Salvina Zrinzo
Article Type: Case Report | First Published: February 05, 2018
Granulosa cell tumours (GCT) are uncommon neoplasms, accounting for 2-5% of all ovarian carcinomas. The pathogenesis of these tumours is characterised by differentiation towards the follicular granulosa cell. However, the exact cell of origin is disputed, with the granulosa cell, thecal cell or fibroblast having been proposed as putative progenitors. A granulosa stem-cell has been described, which has also been suggested as a cell of origin....
Open Access DOI:10.23937/2377-9004/1410116
Septicaemia with Fusobacterium necrophorum from Periodontal Disease in Pregnancy Resulting in Immature Birth: Case Report and Review of Literature
D van der Windt, R Kornegoor, R Walhof, BP Overbeek and KM Paarlberg
Article Type: Case Report | First Published: February 05, 2018
A 26-year-old woman (gravida four, para two) delivered an immature infant at 23 weeks of gestation after presenting with abnormal vaginal blood loss and sepsis. Blood cultures and placenta cultures showed bacteremia by Fusobacterium necrophorum. Histopathological examination of the placenta was concurrent with that, showing severe chorioamnionitis with funisitis. A dentist and oral surgeon confirmed the diagnosis of generalised periodontal disease....
Open Access DOI:10.23937/2377-9004/1410115
Tubo-Ovarian Abscess in Early Pregnancy - Report of a Rare Coexistence
Brandao P , Portela-Carvalho AS, Estevinho C, Soares E and Melo A
Article Type: Case Report | First Published: February 05, 2018
Pelvic inflammatory disease is extremely rare during pregnancy. Both differential diagnosis and management of tubo-ovarian abscesses in pregnancy are challenging and associated with poor obstetric outcomes. The authors present a case of a 17-years-old girl with low abdominal pain for five days. A tubo-ovarian abscess was suspected, with an early pregnancy of unknown location. She was admitted to receive intravenous antibiotics and to rule out ectopic pregnancy....
Open Access DOI:10.23937/2377-9004/1410114
Laparoscopic Management of Interstitial Ectopic Pregnancy with Endo GIA™ without Rupture
Rawan Al Harmi, Rania Hassan, Basma Darwish and Nawal Dayoub
Article Type: Case Report | First Published: February 02, 2018
Interstitial pregnancy is uncommon, accounting for 2-4% of all ectopic pregnancies. It is potentially serious and mortality is most commonly due to rupture and subsequent hemorrhage. Both medical and surgical management options are available, depending on a given individual's case. Currently, the preferred surgical approach is laparoscopy. However, despite the presence of different laparoscopic techniques, there is no consensus on a single best technique. We report a case of a 27-year-old pregna...
Open Access DOI:10.23937/2377-9004/1410113
Managing Tetraplegia and its Associated Risks in Pregnancy and Labour- A Case Report
Fatima Rashed, Summia Zaher, and Marion Beard
Article Type: Case Report | First Published: January 22, 2017
The management of tetraplegic women in pregnancy and labour is a rare event, with sporadic cases reported worldwide. These women often require increased medical input due to potentially life-threatening complications associated with their spinal cord injury. Of these, autonomic dysreflexia is the most widely feared....
Open Access DOI:10.23937/2377-9004/1410112
Biamniotic Parasitic Conjoined Twins with Discordant Genotype
Sofie C Husen, Maarten FCM Knapen, Femke AT de Vries, Robert M Verdijk and Lutgarde CP Govaerts
Article Type: Case Report | First Published: January 20, 2018
Conjoined twin pregnancies are uncommon. The prevalence of conjoined twins in the first trimester of pregnancy is estimated as 1:50,000, with an unexplained female predominance (3:1). It is thought that at 13-14 days gestational age an incomplete fission of the germinal disc causes the development of a conjoined twin pregnancy, obligatory being associated with a monochorionic monoamniotic placentation. ...
Open Access DOI:10.23937/2377-9004/1410111
Tension Free Vaginal Tape Erosion into the Urinary Bladder: A Case Report
Priyanka Singh and Han How Chuan
Article Type: Case Report | First Published: December 28, 2017
The Tension-free Vaginal Tape (TVT) is the most commonly performed procedure for the management of Stress Urinary Incontinence (SUI). There is insufficient data on the occurrence of complications and their management. The incidence of tape erosion and infection is observed to be higher with synthetic non-absorbable slings....
Open Access DOI:10.23937/2377-9004/1410110
Unusual Localization of a Leiomyoma; Vaginal Leiomyoma in a 24 Years Virgin Woman: A Case Report
Najeh Hsayaoui, Wael Mbarki, Hajer Bettaieb, Youssef El Cadhi, Fatma Douik, Hedhili Oueslati, Sana Mezghenni and Chaouki Mbarki
Article Type: Case Report | First Published: December 11, 2017
Vaginal leiomyomas are rare benign solid tumors of the vagina with only about 300 reported cases. Here we describe a 24-year-old sexually inactive patient presented with a vaginal bleeding. On ultrasonography, a 5-centimeter vaginal mass was diagnosis in the anterior vaginal wall under urethra....
Open Access DOI:10.23937/2377-9004/1410109
Ultrasound and Biochemical First Trimester Markers as Predictive Factors for Intrauterine Growth Restriction
Benitez Martin A, Vargas Perez M and Manzanares Galan S
Article Type: Research Article | First Published: December 06, 2017
After analyzing our results, we ascertained that some variables were protective, and others were risk factors for SGA, however a multivariate model established to predict SGA indicates that these were not good predictors of SGA (AUC = 0.65)....
Open Access DOI:10.23937/2377-9004/1410108
Intravenous Leiomyomatosis of the Uterus: A Case Report
Fatma Douik, Najeh Hsayaoui, Hajer Bettaieb, Wael Mbarki, Hedhili Oueslati and Chaouki Mbarki
Article Type: Case Report | First Published: October 30, 2017
Intravenous Leiomyomatosis (IVL) is an unusual clinical condition characterized by histologically benign smooth muscle lesions extending from the uterus into pelvic and systemic veins and, more rarely, into the right cardiac chambers....
Open Access DOI:10.23937/2377-9004/1410107
Anterior Vaginal Wall Epitheloid Leiomyoma: A Case Report
Priyanka Singh, Leong May Ying and Han How Chuan
Article Type: Case Report | First Published: October 26, 2017
Primary paraurethral tumours of benign nature in females are quite infrequent. Physical examination and imaging modalities like ultrasound and magnetic resonance imaging of the pelvis help in characterising the mass morphologically and structurally. They also help to decipher the relationship of the mass with the urethra and the vagina....
Open Access DOI:10.23937/2377-9004/1410106
Management of Maternal Atrial Myxoma in Advanced Pregnancy: A Clinical Dilemma
Emma Wilson, Karthikeyan Gopal, Jay Iyer, Robert Tam, Ryan Schrale and Yaniv Zipori
Article Type: Case Report | First Published: October 16, 2017
In this report, we present a challenging case of pedunculated left atrial myxoma which was initially diagnosed on Transthoracic Echocardiography (TTE) at 39 weeks and 2 days gestation in a grand-multigravida woman with previous normal deliveries. She was delivered by urgent caesarean section with resection of the myxoma on the following day....
Open Access DOI:10.23937/2377-9004/1410105
Outcome of Novasure Endometrial Ablation in Women with Heavy Menstrual Bleeding with or without Dysmenorrhoea, Including Those with Uterine Cavity Length More Than 6.5 cm
Nader Gad, Ashlee Rigby, Alia Vemuri and Mahima Singh
Article Type: Research Article | First Published: October 14, 2017
Heavy Menstrual Bleeding (HMB) is a common health problem and may be associated with iron deficiency anaemia affecting the quality of life of many women. Problems of HMB can be more complicated when it is associated with dysmenorrhea. Traditionally, medical management of HMB has been the first line therapy....
Open Access DOI:10.23937/2377-9004/1410104
Challenges with Cervical Cancer Treatment in Cameroon
Simon Manga, Mireille Kanjo and Wilfred Ngwa
Article Type: Case Study | First Published: October 13, 2017
This is a case study of women with Invasive Cervical Cancer (ICC) and her course of treatment, showing the critical need for prevention through aggressive screening and vaccination programs. Even though cost of treatment was a barrier, she completed her radiation therapy and felt better....
Open Access DOI:10.23937/2377-9004/1410103
Breast Cancer Masquerades as an Endometrial Cancer
Atinuke Akinpeloye, Mohamed Satti, Douglas Congdon and Guy Boike
Article Type: Case Report | First Published: May 12, 2017
Patient A was a 47-year-old African American lady admitted for thrombocytopenia. A mammogram done a few weeks prior to admission was reported as BIRADS 4 for the right breast. She had a biopsy done as an inpatient which revealed invasive lobular carcinoma. Due to persistent vaginal bleeding a gynecological consult was requested....
Open Access DOI:10.23937/2377-9004/1410102
Treatment of Chronic Ovarian Vein Thrombosis
Article Type: Case Report | First Published: March 06, 2017
Ovarian vein thrombosis is a rare condition, occurring most commonly in the postpartum or postoperative period, but has also been identified in cases of malignancy and infection. This report describes a case of chronic ovarian vein thrombosis that most likely developed postoperatively in a patient who was subsequently found to have a malignancy....
Open Access DOI:10.23937/2377-9004/1410101
Laparoscopic Single Mesh Sacrohysteropexy Plus bladder Patch for Pelvic Organ Prolapse
Mai Myoga, Kazuaki Yoshimura, Kazuaki Nishimura, Kaori Hoshino and Toru Hachisuga
Article Type: Case Report | First Published: January 28, 2017
Here we introduce a laparoscopic sacrohysteropexy plus bladder patch procedure as a useful operative procedure for POP patients who desire uterine preservation. A 62-year-old woman, gravida 2 para 2 with pelvic organ prolapse quantification (POP-Q) stage III of uterine prolapse and stage II of cystocele, came to our hospital and desired a POP operation with uterine preservation....
Open Access DOI:10.23937/2377-9004/1410100
Giant Vulvar Leiomyoma: Successful Management in a Poor Setting of a Common Neoplasm in an Uncommon Site
Bang Guy Aristide, Savom Eric Patrick, Missi Amanda Marlene, Metogo Ntsama Junie Annick and Essomba Arthur
Article Type: Case Report | First Published: December 01, 2016
In clinical practice, leiomyoma of the vulva are infrequent and rarely encountered. We report the case of a 36-year-old Cameroonian with a 10-year history of a left labia majora swelling. After evaluating history and clinical examination, a decision of excision of this tumor was taken. Intraoperatively, the mass was well circumscribed with a weight of 480 g. The cosmetic result was good. Histopathology confirmed the diagnosis of vulvar leiomyoma....
Open Access DOI:10.23937/2377-9004/1410099
Hydrops Fetalis Associated with Congenital Cytoplasmic Body Myopathy
Yuki Kodama, Hiroshi Sameshima, Masatoki Kaneko, Hideki Kawaguchi, Tomoaki Ikeda and Tsuyomu Ikenoue
Article Type: Case Report | First Published: November 26, 2016
A 27-year-old, gravida 3, para 1 Japanese woman was transferred to our hospital because of fetal pleural effusion and polyhydroamnios at 33 weeks of gestation. She had a family history of amyotrophic lateral sclerosis in her maternal uncle. Her first child, a 3-year-old boy, was healthy. The pregnancy had been uneventful until 33 weeks, when the patient noticed the fetus was less active than before. On admission, the fetus had bilateral pleural effusion, ascites, and subcutaneous edema. The amni...
Open Access DOI:10.23937/2377-9004/1410098
Challenges Diagnosing Appendiceal Neoplasms during Pregnancy
Vidya Bharati, Angeles Alvarez Secord, Thomas M Price and John Migaly
Article Type: Case Report | First Published: November 01, 2016
A 31 y.o. G1P0 at 18 weeks estimated gestational age was found to have an echogenic 7.8 cm by 3.1 cm mass adjacent to the uterine fundus during an anatomy scan. Follow-up radiology performed abdominal ultrasound was normal. Patient delivered vaginally without incident. Three years later she was diagnosed with a right complex pelvic mass identified during a saline infusion sonogram for fertility evaluation. Carcinoembryonic antigen was elevated. Laparoscopic surgery revealed appendiceal mass and ...
Open Access DOI:10.23937/2377-9004/1410097
Cyst of Canal of Nuck: Our Experience
Juan Piazze, Ettore Palma, Francesco Recchia, Valerio D'Orazi, Daniela Romanzi, Michele Rosselli, Massimo Bratta and Silvio Rea
Article Type: Case Series | First Published: October 01, 2016
We report two cases of a cyst of the canal of Nuck in which sonography showed a tubular cystic structure characterized by internal septum localized within the inguinal canal. Unfortunately, Magnetic resonance (MRI) examination was not performed in the first case, however in the second case, MRI demonstrated that the mass suggested an hydrocele of the Canal of Nuck. Both cases were solved satisfactorily and confirmed cysts of canal of Nuck by means of laparoscopic technique....
Open Access DOI:10.23937/2377-9004/1410096
Pheochromocytoma in Pregnancy: A Review of the Literature
A Yulia, I W Seetho, A Ramineni and RAK Jaiyesimi
Article Type: Review Article | First Published: September 24, 2016
pheochromocytoma in pregnancy is a life-threatening condition. Although it is rare, if the diagnosis is missed or mismanaged, it has detrimental effect on both mother and fetus, with mortality up to 58%. Diagnosis of pheochromocytoma in pregnancy remains a huge challenge faced by clinicians due to its non-specific signs and symptoms and the fact that it mimics other conditions which occur much more commonly in pregnancy....
Open Access DOI:10.23937/2377-9004/1410095
The Anesthetic Approach for a 27-Week Pregnant Woman Undergoing Endoscopic Sinus Surgery
Nilay Boztas, Sevda Ozkardesler, Mert Akan and Mine Sari
Article Type: Case Report | First Published: September 02, 2016
In pregnancy non-obstetric surgery involves many significant difficulties for the anesthetist. The majority of these procedures are non-elective and some are life-threatening. This report explains the preoperative preparation and general anesthetic method for a 27-week pregnant woman with osteofibrotic mass narrowing the left optic canal causing rapidly advancing loss of vision....
Open Access DOI:10.23937/2377-9004/1410094
Supraclavicular Lymph Node as a Presentation of Fallopian Tube Cancer
Mohamed Satti, Ahmed Abdelaziz, Pouya Abhari and Guy Boike
Article Type: Case Report | First Published: September 01, 2016
A 44-year-old female presented with a large firm mass involving the left side of her neck; she denied any other symptoms. A CT scan was performed which was consistent with a 5.9 cm left-sided neck mass. A fine needle aspiration biopsy was consistent with poorly differentiated adenocarcinoma, and a serum CA125 was normal. Subsequently, a PET scan was performed and revealed increased uptake in the para-aortic and retroperitoneum lymph nodes; a soft tissue mass was seen in the left hemi-pelvis....
Open Access DOI:10.23937/2377-9004/1410093
Breus Mole: A Placental Anomaly in a Patient Undergoing a Dilation and Evacuation
Navdeesh Reiners, Victor Sai, Nagesh Ragavendra, Aparna Sridhar and Angela Chen
Article Type: Case Report | First Published: August 06, 2016
A 22-year-old woman presented at 21+1 weeks for dilation and evacuation. Sonographic features were consistent with a Breus mole. Intraoperatively, traction and massage were used to deliver the placenta; the patient quickly achieved hemostasis. Final pathology showed a fibrin lined intervillous cystic structure compatible with a Breus mole....
Open Access DOI:10.23937/2377-9004/1410092
Termination of Pregnancy for an 11q Terminal Deletion Incidentally Diagnosed Prenatally; Jacobsen Syndrome Penetrance and Ethical Dilemmas
Sofia F Makrydima, Eftihios Trakakis, Athanasios Minkoff and Nikolaos Papantoniou
Article Type: Case Report | First Published: July 05, 2016
The currently noted boost of de novo microdeletions has been partly attributed to the relevant increase of mean paternal age at the time of first child acquisition. The simultaneous widespread implementation of molecular techniques for prenatal karyotyping has revealed distinct deletion aberrations of uncertain clinical significance. Recent research has failed to confirm the intrinsic correlation between implicated genome fragment and extent of phenotypic abnormality....
Open Access DOI:10.23937/2377-9004/1410091
Clinical Observation of 84 Days Delayed Delivery of the Second Fetus in Twin Pregnancy
Julia E Dobrokhotova, Oleg V Makarov, Pavel V Kozlov and Pavel A Kuznetsov
Article Type: Case Report | First Published: July 04, 2016
Perinatal morbidity and mortality in preterm labor is significantly higher than in on-term delivery. The share of preterm infants accounts for approximately 70% of all cases of early neonatal mortality. One of the most important independent risk factors for preterm birth is multiple pregnancy. The risk of delivery before 30, 32 and 34 weeks in twin pregnancy is about 4%, 8% and 16%, respectively. In general, the frequency of preterm labor with twins is 6 times higher than in singleton pregnancie...
Open Access DOI:10.23937/2377-9004/1410090
The Use of Advanced Reproductive Technologies while Breastfeeding: A Role for in Vitro Maturation
Catherine S Rose and Bruce I Rose
Article Type: Case Report | First Published: July 01, 2016
Breastfeeding provides significant health benefits for both the mother and child. There is a decreased risk of ovarian and breast cancer, the development of diabetes, and myocardial infarction for women who breastfed their child. The risk decreases even more significantly if the mother is exclusively breastfeeding without supplementation of formula and the longer the mom and baby choose to breastfeed. For the child, breastfeeding decreases the risk of childhood leukemia, childhood obesity, asthm...
Open Access DOI:10.23937/2377-9004/1410089
Aggressive Complete Hydatidiform Mole Coexistent With A Normal Fetus During Pregnancy: Is There A Correlation Between Outcome, and Serum HCG Levels? A Report on 2 Cases and Review of the Literature
Nathalie Renard, SWA Nij Bijvank, HH De Haan, J van Eyck, JWB de Groot, RHM Verheijen and AJ Kruse
Article Type: Case Series | First Published: June 01, 2016
wo cases of complete hydatidiform mole with coexisting fetus are described. In the first case, the mole of this twin pregnancy displayed an aggressive behavior with early maternal onset of severe pre-eclampsia and lung and liver metastases. The second patient opted for termination of pregnancy prior to a possible onset of complications. Existing literature on this topic is also reviewed, in particular on the role of serum hCG levels to predict a favourable fetal prognosis....
Open Access DOI:10.23937/2377-9004/1410088
Sacral Nerve Stimulation and Fecal Incontinence: Current Uses and Emerging Trends
Jennifer E Hrabe, Brooke Gurland and Tracy L Hull
Article Type: Short Review | First Published: May 21, 2016
Fecal incontinence (FI) is a socially devastating condition affecting both men and women. Patients often suffer in silence, as FI is frequently unreported. It is commonly seen in patients who also experience urinary incontinence (UI). Risk factors for FI include obstetrical trauma as well as increasing age. Until recently, treatment options were limited and consisted of medical therapy or surgical options with limited efficacy or high morbidity. Initially used for UI, sacral nerve stimulation ha...
Open Access DOI:10.23937/2377-9004/1410087
Isolated Rectal Laceration Following Normal Spontaneous Vaginal Delivery and Delayed Rectal Hemorrhage
Article Type: Case Report | First Published: May 21, 2016
A 37-year-old Para 0 patient underwent an induction of labor due to chronic hypertension. She had a successful normal vaginal delivery but experienced acute cardiovascular collapse immediately following the delivery requiring massive transfusion. She also was found to have an isolated rectal laceration without laceration of anus or anal sphincter. After she was discharged home she presented to the emergency room with rectal hemorrhage 5 days after the initial repair requiring an additional two u...
Open Access DOI:10.23937/2377-9004/1410086
Dextroposition of the Heart Reflected Mosaic Fetal Trisomy 18
Mohamed A Satti, Frederico G Rocha, Erin Beaver and Jeffrey M Dicke
Article Type: Case Report | First Published: May 02, 2016
Anatomy scan of a 22 year old prima gravida at 19w4d showed a viable IUP with unilateral choroid plexus cyst and dextroposition of the heart without any other observed structural malformation. Amniocentesis revealed a normal male pattern for chromosomes 13, 18, 21, X and Y by fluorescence in situ hybridization (FISH). However, chromosomal microarray analysis (CMA) for circulating fetal DNA in maternal blood was consistent with mosaic Trisomy 18. The karyotype of cultured dividing cells confirmed...
Open Access DOI:10.23937/2377-9004/1410085
Successful Treatment of A Primary Cervical Diffuse Large B-Cell Lymphoma with Rituximab-CHOP Immunochemotherapy
Diaz-De La Noval B, Hernandez A, Zapardiel I, De-Santiago J and Diestro Tejeda
Article Type: Case Report | First Published: May 02, 2016
We describe a 46-year-old healthy woman with primary extranodal Non-Hodgkin's diffuse large B-cell lymphoma of the uterine cervix Ann Arbor stage IIEA IPI 1. She presented an acute renal failure and severe ureterohydronephrosis successfully treated with 6 courses of chemotherapy based on Rituximab plus Cyclophosphamide, Doxorubicin, Vincristine and Prednisone (R-CHOP) with no major side effects....
Open Access DOI:10.23937/2377-9004/1410084
Cutaneous Horn of the Breast: A Rare Clinical Feature
Cedric Nadeau, David Desseauve and Emilie Laban
Article Type: Letter to Editor | First Published: April 11, 2016
A benign cutaneous horn was evocated as its base was thin but the diagnostic of a pre invasive intraepithelial dysplasia or squamous cell carcinoma of the skin had to be eliminated by histological examination. It looked like a solid elongated keratinized tumor connected to the skin by a thin bridge of pink/red regular skin (Figure 1 and Figure 2). No evidence of pre invasive skin lesion was found around. The patient had an excision of the lesion and its base under local anesthesia....
Open Access DOI:10.23937/2377-9004/1410083
The Confusion of Mothers with Gestational Diabetes Mellitus due to the Multidimensionality of Healthcare and Therapeutic Care: A Serious Threat to Mother and Fetus's Health
Fatemeh Ghaffari, Zahra Rahnavard, Mahvash Salsali and Soroor Parvizi
Article Type: Research Article | First Published: April 05, 2016
Gestational diabetes mellitus (GDM) is a challenge of the 21st century. The management of the diseases confronts numerous issues which lead to undesirable results of care consequences. The aim of this study is to explain factors involved in the confusion of mothers with GDM due to the multidimensionality of healthcare and therapeutic care. The present study was carried out in 2014 with a qualitative method. Purposive sampling was employed to select 17 pregnant women with GDM who had referred to ...
Open Access DOI:10.23937/2377-9004/1410082
Amniotic Fluid Embolism: Combined Treatment with Surgery and Extracorporeal Membrane Oxygenation Support - A Case Report
Arnon Wiznitzer, Rinat Gabbay-Benziv, Eran Altman, Dan Aravot and Philippe Biderman
Article Type: Case Report | First Published: March 28, 2016
A 42-year-old gravida 1, 40-weeks' gestation, presented with rupture of membranes in labor. Her history and prenatal care were unremarkable except for obesity. On physical examination, blood pressure was 156/91 mmHg with no other signs of pre-eclamsia. Due to non-progression at active labor, cesarean section was performed with extended "top-up" epidural and delivery of a healthy boy. Immediately after removal of the placenta, the patient reported chest pain, and became unresponsive. ECG (electro...
Open Access DOI:10.23937/2377-9004/1410081
An Idiopathic Case of Recurrent Spontaneous Ovarian Hyper Stimulation Syndrome
Alessandra Ainsworth, Zaraq Khan and Jani Jensen
Article Type: Case Report | First Published: March 26, 2016
We report a case of recurrent spontaneous ovarian hyperstimulation syndrome (OHSS). The patient presented at 8 weeks gestation. Due to severity of symptoms, the patient required both inpatient and outpatient management. Her symptoms resolved at 11 weeks gestation and the pregnancy was carried to term. Recurrent spontaneous OHSS is a rare and potentially morbid event. While most cases will eventually resolve, patients require careful diagnosis, surveillance, and supportive care....
Open Access DOI:10.23937/2377-9004/1410080
Urinary Incontinence as a Presenting Symptom of Bladder Cancer
Elena Vilar Gonzalez, Marta Perez de la Fuente, Enrique Gonzalez Diaz
Article Type: Case Report | First Published: March 25, 2016
Urinary incontinence is a very common complaint among women. We should think of potentially serious aetiologies when there is no response to empiric treatments, especially in postmenopausal women. We report a case of a 69 year old woman, referred to our pelvic floor unit with urinary incontinence and nocturia. After failing with anticholinergic treatment, a transvaginal ultrasound scanning shows an irregular solid lesion of 6 mm, which was diagnosed by further urological investigation as a trans...
Open Access DOI:10.23937/2377-9004/1410079
Postpartum Low Back Pain: It is not always What You Think
Melissa Corso, Diane Grondin and Carol Ann Weis
Article Type: Case Report | First Published: March 18, 2016
Postpartum back pain is common, with up to 75% of women experiencing back pain immediately following birth. This pain can be moderately to severely debilitating to the new mom, affecting activities of daily living such as caring for her new born, sleep patterns, and otherhousehold activities. However, all low back pain is not created equal and we document a case study with an unusual cause of postpartum back pain....
Open Access DOI:10.23937/2377-9004/1410078
Management of Pregnancy in a 24 Year Old Woman with Cervical Cancer in Resource Limited Settings: Case Report
Elichilia R Shao, George Semango, Kevin V Nandonde and Richard Rumanyika
Article Type: Case Report | First Published: March 03, 2016
Cervical cancer (CaCx) among immune competent young women is quite rare. Its management is a challenge especially in resource limited settings. We report management of pregnancy in a 24 year old woman with CaCx in Mwanza, Tanzania. A 24-year-old Tanzanian black women gravida three at 23 weeks of gestational age (GA) came to our hospital complaining of heavy vaginal bleeding mixed with foul smell discharges for about 2 months....
Open Access DOI:10.23937/2377-9004/1410077
An Internet Survey of Women with Unicornuate Uterus: Pregnancy Outcomes by Classification
Article Type: Original Research | First Published: March 02, 2016
Unicornuate Uterus is a rare uterine anomaly that currently has very little scientific research on the reproductive possibilities and experiences of women with this condition, the majority of research is done on individual case studies. This article seeks to gain a wider look at all of the reproductive complications that women with Unicornuate uterus encounter, and also to investigate if there are statistically significant differences between subclasses in regards to reproductive outcomes....
Open Access DOI:10.23937/2377-9004/1410076
Investigating Alcohol Consumption during Pregnancy for the Prevention of Fetal Alcohol Spectrum Disorders (FASD)
Mauro Ceccanti, Daniela Fiorentino, Paola Ciolli, Giovanna Coriale, Marisa Patrizia Messina, Maria Concetta Marcella Scamporrino, Simona Solombrino, Marco Fiore and Valentina Carito
Article Type: Review Article | First Published: March 01, 2016
The term FASD (Fetal Alcohol Spectrum Disorders) is used to describe the entire spectrum of pathologies and disorders caused by alcohol exposure in uterus. Alcohol assumed in pregnancy passes directly through the placental barrier causing a broad range of symptoms whose severity can greatly vary in degree. The alcohol teratogenic effect may result in physical damage and specific facial anomalies, growth delays, neurological defects along with intellectual disabilities and behavioral problems....
Open Access DOI:10.23937/2377-9004/1410075
"The Association between Child Loss, Children's Paternity and High Parity in Dar Es Salaam, Tanzania": A Cross Sectional Survey at the National Referral Hospital
Andrew H. Mgaya, Hussein L. Kidanto and Hans N. Mgaya
Article Type: Research Article | First Published: February 26, 2016
A cross-sectional study conducted at Muhimbili National referral Hospital in Tanzania inquired about and compared age, socioeconomic status, perception of obstetric risks of grand multiparity, contraceptive knowledge and practice, obstetric history and having children of different paternity, between grand multiparas and lower parity women using Chi-square and student's t-tests....
Open Access DOI:10.23937/2377-9004/1410074
A Rare Case of Mekel's Diverticulum Perforation by the Gangrenous Appendicitis during Pregnancy
Cinzia Orlandini, Nathalie Conti, Alessandra Pizzo, Elisabetta Guerrini, Luigi Verre, Felice Petraglia and Stefano Luisi
Article Type: Case Report | First Published: February 22, 2016
Meckel's diverticulum is one of the most common congenital malformations of the small intestine and it results from an incomplete obliteration of the omphalomesenteric or vitelline duct. The position of Meckel's divericulum along the length of the small intestine is variable, but is usually found within 100cm of the ileocecal valve. Perforated Meckel's diverticulum is a rare complication during pregnancy. Its presentation is similar to appendicitis and its diagnosis must be considered in all cas...
Open Access DOI:10.23937/2377-9004/1410070
A Rare Case of Acute Pseudo-Meigs' Syndrome Presenting with Pleural Effusion and Ascites and a Ruptured Leiomyoma and Hemorrhagic Shock
Matthew Cowan, Janine Crantz, Stephanie Welsh, William Nahhas and Steven R Lindheim
Article Type: Case Report | First Published: January 28, 2016
Meigs' Syndrome is classically described as a triad of benign solid ovarian tumor with the gross appearance of a fibroma (either a fibroma, thecoma, or granulosa cell tumor) accompanied with ascites and pleural effusion. In contrast, pseudo-Meigs' Syndrome presents with ascites and pleural effusion but with any other pelvic mass, including mature teratomas, struma ovarii, and leiomyomata of the ovary, fallopian tube, or uterus....
Open Access DOI:10.23937/2377-9004/1410073
Vulvar Abcess due to Actinomyces Meyerii
Article Type: Case Report | First Published: January 30, 2016
A 14 years old girl presented with vulvar swelling, pain, and difficulty to walk. Her examination showed a tender and large left labial abscess (Figure 1). In OR, the patient underwent incision and drainage. Large amounts of puss were evacuated. Aerobic and anaerobic cultures were obtained. The patient's postoperative recovery was unremarkable and she was discharged on oral Ciprofloxacin 250 mg twice a day and Cephalexin 500 mg twice a day for 7 days....
Open Access DOI:10.23937/2377-9004/1410072
Robotic Assisted Repair of Bilateral Fallopian Tube Prolapse after Vaginal Hysterectomy
Ruben J. Barrera -Vera, Kimberley Chiu, Perry Cohen, Victoria Chernyak and Nicole S. Nevadunsky
Article Type: Case Report | First Published: January 30, 2016
Hysterectomy is the most frequent major surgical procedure performed in gynecology. Fallopian tube prolapse into the vaginal vault is a rare but known reported complication of hysterectomy, estimated to occur in approximately 0.1% of procedures, although the true incidence of this complication is difficult to estimate, as many cases are either unreported or unrecognized. It is three times more frequent after vaginal hysterectomy....
Open Access DOI:10.23937/2377-9004/1410071
Broad Ligament Hernia after Cesarean Section
Christopher M Tarney, Johnnie Wright Jr and Karen Wilson
Article Type: Case Report | First Published: January 29, 2016
Small bowel obstruction is rare after cesarean section but can become a surgical emergency. As the rate of cesarean deliveries increases, the frequency of complications will likely increase. A 26-year-old woman, gravida 3 para 2002, underwent emergent cesarean section at term for non-reassuring fetal status. The procedure was complicated by difficulty returning the uterus to the abdomen after exteriorization for hysterorrhaphy. She was readmitted and brought to surgery on postoperative day five ...
Open Access DOI:10.23937/2377-9004/1410069
Latrogenic Myometrial Defect Following Fetoscopic Laser Therapy for Twin-Twin Transfusion Syndrome (TTTS)
Stephanie L Cooper, Sean Spence, David Somerset, Rory Windrim and Greg Ryan
Article Type: Case Report | First Published: January 23, 2016
Monochorionic twin pregnancies have significantly increased risk of fetal loss, perinatal mortality and morbidity compared to dichorionic twin and singleton gestations. Twin to twin transfusion syndrome (TTTS) occurs in 10-15% of these twins, and is the most important cause of mortality....
Open Access DOI:10.23937/2377-9004/1410068
Uterine Arteriovenous Malformations and its Imitators: Is there a Role for Hysteroscopy?
Christopher M Tarney, Saioa Torrealday and Jason Parker
Article Type: Case Report | First Published: December 28, 2015
Uterine arteriovenous malformations (AVMs) are an uncommon vascular disease occurring in women during the reproductive years, which can lead to life-threatening vaginal bleeding. The prevalence of AVMs is unknown with less than 100 case reports described in the literature. Uterine AVMs may be congenital or acquired; risk factors for the latter include early pregnancy loss, pregnancy termination, and instrumentation of the uterus, cervical or endometrial cancer, endometritis, and trophoblastic di...
Open Access DOI:10.23937/2377-9004/1410067
Growing Teratoma Syndrome Concurrent with Pregnancy: A Case Report and Literature Review
Aki Tanaka-Murakami, Masakazu Abe, Yuka Kasamatsu, Nobuhiro Kado, Shiho Kuji, Nobutaka Takahashi, Munetaka Takekuma and Yasuyuki Hirashima
Article Type: Case Report and Literature Review | First Published: November 30, 2015
Growing teratoma syndrome (GTS) is a rare disease characterized by the appearance of benign metastatic lesions during or after chemotherapy for germ cell tumor. Complete surgical resection is important for the diagnosis and cure of GTS. We encountered a patient with a suspected GTS during her second pregnancy and childbirth; 4 years later, radical surgery confirmed the diagnosis. A tumor that was suspected to be GTS was observed in a 31 year old 2 para woman immediately after the completion of f...
Open Access DOI:10.23937/2377-9004/1410066
Familial Hypercholesterolemia and Pregnancy: Risk and Management
Roberta Mombelli and Giuliana Mombelli
Article Type: Review Article | First Published: November 18, 2015
Familial hypercholesterolemia (FH) is a dominantly inherited disorder present from birth with elevated levels of low-density lipoprotein (LDL) cholesterol and increased risk for premature coronary heart disease (CHD) with clinical manifestation between the first and the fourth decades of life. Although statins are the most effective therapy for individuals with FH the use of statins is contraindicated during pregnancy. For this reason, before of a pregnancy the lipid-lowering drugs are discontin...
Open Access DOI:10.23937/2377-9004/1410065
VIA and Challenges of a Single Visit Approach in Malawi
Haeok Lee, Mary Sue Makin, Jasintha T Mtengezo and Address Malata
Article Type: Case Report | First Published: November 01, 2015
Cancer of the cervix is the most common cancer in women in sub-Saharan Africa. This is a report of the experience of a 25 year-old HIV negative woman with five children who was detected with a precancerous lesion with VIA at a local health facility. She was referred for post-VIA treatment at another facility 60 Km away. She traveled all day for her follow-up treatment and spent all her money to get there so that she had none remaining to pay for food or her return bus fare. This case study point...
Open Access DOI:10.23937/2377-9004/1410064
Left Vaginal Obstruction and Complex Left Uterine Horn Communication in a 12 Year Old Female
Barry E. Perlman, Amy S. Dhesi, Gerson Weiss
Article Type: Case Report | First Published: October 29, 2015
Obstructive Mullerian duct anomalies are an infrequently encountered clinical problem. The use of imaging and surgical exploration allowed for diagnosis and treatment of symptoms of a complex obstructive mullerian anomaly. We present a case of a 12 year old female with a history of intermittent lower abdominal pain and absent left kidney who was found to have an obstructed left vagina and complex left uterine horn communications resulting in hematocolpos, hematometra, and endometriosis....
Open Access DOI:10.23937/2377-9004/1410063
Turner Syndrome and Infertility: A Review of Literature
Emine Demirel, Emre Ekmekci, Zeynep Soyman and Sefa Kelekci
Article Type: Review Article | First Published: October 28, 2015
Fertility of women with Turner Syndrome is now being more interested due to the new improvements in assisted reproductive techniques. Turner Syndrome is characterized by the premature atresia of ovarian follicules. Atresia starts at intrauterine period and continues till all ovarian follicules go to atresia. The time of this period changes from patient to patient. Also Turner Syndrome is related with higher risks in pregnancy. These include higher incidence of spontaneous abortion, fetal anomaly...
Open Access DOI:10.23937/2377-9004/1410062
Placental Abruption Diagnosed by the Lab Technician
L MacDonald, F Waterson, S Marshall and A Cope
Article Type: Case Report | First Published: September 30, 2015
Placental abruption is the separation of the placenta from the uterus. Diagnosis of placental abruption is largely a diagnosis of exclusion and ultrasound is not diagnostic. A case of a placental abruption diagnosed by the presence of two blood types in the group and save sample is presented. A thorough search of the relevant databases would suggest that this is the first reported case of such....
Open Access DOI:10.23937/2377-9004/1410061
Primary Umbilical Endometrioma: A Case Report
Lim Leek Mei and Mickael Hoong Farn Weng
Article Type: Case Report | First Published: September 30, 2015
We report a case of primary umbilical endometrioma. She was a 41year old lady, para 1+1 with a background history of type2 diabetes mellitus, hypertension and a previous uneventful Caesarean section in 2005. She was subfertile since then. She presented with scanty painless bleeding from the umbilicus for past 5 months which coincided with her menses. The bleed would start a few days before her menses and ceased by day two, in small amount and painless. Her cycles were regular with normal flow a...
Open Access DOI:10.23937/2377-9004/1410060
Adenomyoma of Endocervical Type of the Cervix Uteri with Reactive Atypia and Goblet Cell Differentiation - A Case Report and Review of the Literature
Steffen Hauptmann, Katja Mohr and Regina Grosse
Article Type: Case Report | First Published: September 30, 2015
In this report we present the rare case of a 53 years old woman with an adenomyoma of endocervical type of the cervix uteri with reactive atypia and focal goblet cell differentiation. The epithelium of the lesion was MUC5AC positive, making this marker invalid in excluding the most important differential diagnosis of this lesion, the minimal deviation adenocarcinoma. The most relevant literature is reviewed and the differential diagnoses are discussed....
Open Access DOI:10.23937/2377-9004/1410059
Case Report: Gestational Diabetes Mellitus: 2 Cases Diagnosed and Treated Using IADPSG Criteria. The Debate Goes On
Alejandra Duran Rodriguez-Hervada, Amparo Sabate Garcia, Consuelo Aunon Pereda, Carla Assaf-Balut, Miguel A Rubio, Nuria Izquierdo Mendez, Noelia Perez Perez, Miguel A Herraiz Martinez, and Alfonso L Calle-Pascual
Article Type: Case Report | First Published: September 28, 2015
Gestational Diabetes Mellitus (GDM) is an important public health problem, given its high prevalence and its association with adverse maternal and fetal outcomes. Recent evidence has confirmed that the risk of adverse outcomes is a continuum, increasing as maternal blood glucose levels rise. Furthermore, women with prior GDM are a high-risk group for the future development of diabetes, metabolic syndrome, and cardiovascular disease....
Open Access DOI:10.23937/2377-9004/1410058
Ovarian Stromal Hyperthecosis and Hyperandrogenemia Refractory to Hormonal Suppression
Gregory M Gressel, Natalia Buza, Shirley M McCarthy and Pinar H Kodaman
Article Type: Case Report | First Published: September 26, 2015
Ovarian stromal hyperthecosis (OSH) is an uncommon clinical entity. According to the 2014 WHO classification of gynecologic tumors, it has been documented in one-third of patients older than age 55 years of age in autopsy studies. This disorder usually presents in the second or third decade of life with menstrual irregularity as well as signs of virilization. Presentation in the post-menopausal period is less common, but has been reported....
Open Access DOI:10.23937/2377-9004/1410057
Bochdalek Diaphragmatic Hernia Complicating Pregnancy in the third Trimester: Case Report
Monica Hernandez-Aragon, Laura Rodriguez-Lazaro, Raquel Crespo-Esteras, Leyre Ruiz-Campo, Ignacio Adiego-Calvo, Jose Manuel Campillos-Maza, Sergio Castan-Mateo
Article Type: Case Report | First Published: August 07, 2015
A 32-year-old primiparous woman was diagnosed of diaphragmatic hernia at 29 weeks' gestation and transferred to our hospital. Initially, gastrointestinal symptoms mimicked pathology related to pregnancy, but failure of conservative measures led to performing imaging tests. It was a Bochdalek hernia containing small bowel loops, colon and omentum but not stomach. She was stabilized, but finally cesarean delivery and hernia repair were performed at 32 weeks because of her symptoms, with a successf...
Open Access DOI:10.23937/2377-9004/1410056
Management of Spontaneous Rupture of the Amnion with an Intact Chorion
Jenny A. Jacob, Norman A. Ginsberg, Lee P. Shulman and Leeber Cohen
Article Type: Case Report | First Published: August 06, 2015
Idiopathic severe preterm oligohydamnios as a result of spontaneous rupture of the amnion with an intact chorion is a rare event with a scarcity of reports found in the literature. We evaluated the impact of serial amnioinfusions on this unusual occurrence. This is a followup of a 37-year-old woman with idiopathic severe oligohydramnios diagnosed at 18 weeks of gestation. We performed fie serial amnioinfusions with the purpose of improving fetal lung maturity and to prevent Potter anomalad. At 3...
Open Access DOI:10.23937/2377-9004/1410055
The Case of 11w+ 2d Fetal Heart Rate Positive Unruptured Cervical Pregnancy
Onder Sakin, Bulent Kars, Ilke Tanir and Omer Talip Turhan
Article Type: Case Report | First Published: August 05, 2015
The treatment of cervical pregnancy which is one of the rarest forms of ectopic pregnancy is one of the cases difficult decisions need to be taken. Many years ago when hysterectomy was the only treatment and in case of late treatment decision, 50% of maternal mortality was seen, which results in a change of status with the shape of the high-risk pregnancies' extremely minimal invasive treatment may be possible Moreover, the patient fertility will be preserved and hysterectomy and the negative si...
Open Access DOI:10.23937/2377-9004/1410054
Postmenopausal Calcified Pedunculated Large Subserous Leiomyoma: A Case Report
Ozhan Ozdemir, Cemal Resat Atalay, Mustafa Erkan Sari, Ertugrul Sen and Mehriban Nebioglu
Article Type: Case Report | First Published: August 03, 2015
A 72-year-old postmenopausal and nullipar woman presented with abdominopelvic pain and a palpable mass in the right lower quadrant. Ultrasonography showed a large, hyperechoic, solid mass. Contrast-enhanced computed tomography (CT) of the abdomen demonstrated a well-circumscribed mass. Rutine laboratuary tests and tumour markers revealed as normal. Total abdominal hysterectomy and bilateral salpingo-oophorectomy is the surgery of choice in this case. Histopathological examination confirmed a cal...
Open Access DOI:10.23937/2377-9004/1410053
Cervical Varices Presenting as Vaginal Bleeding: A Description of Two Cases and A Management Plan
Kathy Chyjek, Catherine Hutz, Charles Macri, Jeffrey Berger, Anthony Venbrux, Nadia Khati, Dorothy Bulas and John Larsen
Article Type: Case Report | First Published: August 01, 2015
We present two cases of cervical varices found in the setting of second and third trimester bleeding, report on the clinical outcomes and propose a management plan. Both of our patients were delivered between 38-39 weeks gestation and required interdisciplinary meetings between Obstetrics and Gynecology, Anesthesiology, Neonatology and Interventional Radiology to prepare for delivery....
Open Access DOI:10.23937/2377-9004/1410052
Pregnancy Outcome in Women with History of Uterine Rupture or Dehiscence
Sagy Shick and Ran Neiger
Article Type: Case Series | First Published: July 30, 2015
The rate of Cesarean deliveries continues to increase world-wide. Cesarean delivery, in particular when repeated, is associated with an increased risk of several complications in subsequent pregnancies, including uterine rupture and uterine dehiscence. Rupture of a uterine scar is defined as a disruption of the full thickness of the uterine wall including the overlying visceral peritoneum (uterine serosa). It occurs most frequently in women who have undergone previous uterine surgery (e.g. Cesar...
Open Access DOI:10.23937/2377-9004/1410051
Intestinal Obstruction due to Endometriosis Involving Atypical Hyperplasia: A Case Report
Mehmet B. Senturk, Hakan Guraslan, Bulent Babaoglu and Mesut Polat
Article Type: Case Report | First Published: July 24, 2015
Intestinal endometriosis is not a rare entity. However, malignant transformation and emergency clinical table such as intestinal obstruction due to endometriosis are rare. This is an important condition because it requires a multidisciplinary approach and careful pathologic intervention especially in mass lesions. The case is here presented of a patient who underwent laparotomy in the emergency surgery clinic because of intestinal obstruction. The pathology analysis revealed atypical endometrial...
Open Access DOI:10.23937/2377-9004/1410050
Diagnosis and Management of Embryonal Rhabdomyosarcoma in a Woman with Prolapsing Cervical Mass
Elizabeth V. Connor and Paul A. Disilvestro
Article Type: Case Report | First Published: July 10, 2015
Background: Cervical rhabdomyosarcoma is very rare, comprising less than 1% of cervical cancers in adult women. Less than 40 cases of cervical rhabdomyosarcoma have been reported in adult women in the last 50 years. Due to the rarity of this disease, management guidelines are non-existent. Case: We present a 36-year-old woman who presented with pelvic pain and a vaginal mass. The mass was excised, and pathology confirmed poorly differentiated embryonal type rhabdomyosarcoma....
Open Access DOI:10.23937/2377-9004/1410049
Uterine Tumour Resembling Ovarian Sex Cord Tumour (UTROSCT): Experience with a Rare Disease. Two Case Reports and Overview of the Literature
Brenda Hermsen, Fabrizio Bogliatto, Maaike Bleeker, Luciano Leidi, Hans Trum, Erika Comello and Christianne Lok
Article Type: Case Report | First Published: July 09, 2015
Background: Uterine tumour resembling an ovarian sex cord tumour (UTROSCT) is a rare neoplastic lesion. Patients are generally of reproductive age. Although conservative treatment to preserve fertility has been reported, literature on the optimal treatment on UTROSCT is scarce and only case reports or small case series are available. Aim: To describe the difficulties and resemblances of two different cases of UTROSCT in a pre- and post-menopausal woman in order to classify this uncommon tumour.....
Open Access DOI:10.23937/2377-9004/1410048
Retroperitoneal Lymphoma Presenting as Gynecologic Malignancy: Case Report and Review of the Literature
Devin Miller, Sarah Andiman, Elena Ratner and Diana English
Article Type: Case Report | First Published: July 04, 2015
Pelvic malignancy is commonly thought to represent a gynecologic primary on presentation. In reality, the differential diagnosis is wide and tumors which do not fit typical patterns on imaging or initial pathology can present a significant diagnostic dilemma as these patients may undergo radical gynecologic surgery unnecessarily. We present the case of a 63 year old female presenting with abdominal pain, back pain, weight gain, and hydronephrosis with acute kidney injury. She was initially admit...
Open Access DOI:10.23937/2377-9004/1410047
Minimal Deviation Adenocarcinoma Associated with High-Grade Squamous Cervical Intraepithelial Neoplasia
Carlos Villegas-Cruz, Alhely Lopez Arias, Delia Perez Montiel, Jose Chanona-Vilchis, Luis Alonso Herrera Montalvo and David Cantu de Leon
Article Type: Case Report | First Published: June 30, 2015
Cancer of the uterine cervix is the second cause of cancer at the worldwide level in women, with an incidence of 529,409 new cases annually and is the third place in mortality with 274,883 deaths; in Mexico it represents the second cause of cancer in women with 10,186 new cases each year and the second cause of cancer-related mortality with 5,061 cases, second only to breast cancer....
Open Access DOI:10.23937/2377-9004/1410046
Mieczyslaw R. Gajda, Masoud Mireskandari, Harald Winzer, Herbert Diebolder, Matthias Regensberger, Ingo B. Runnebaum and Iver Petersen
Article Type: Case Report | First Published: June 28, 2015
Liposarcoma is the most common soft tissue sarcoma in adults. It typically occurs in retroperitoneum or extremities. However, this malignant tumor is very rare in the female reproductive system. In this article we present detailed clinical and histopathologic features of a case with liposarcoma of vagina and review the literature on this theme using PUBMED database. The tumor was presented as a rapidly growing mass in the vagina in a 50 year old woman. Pathological evaluation of the biopsy speci...
Open Access DOI:10.23937/2377-9004/1410045
Sclerosing Stromal Tumor of the Ovary in Postmenopausal Women: A Report of Two Cases
Chae Min Lee, Soyi Lim, Hyun Yi Cho, Seung Yeon Ha and Jin Woo Shin
Article Type: Case Report | First Published: June 19, 2015
Sclerosing Stromal Tumor (SST) was first delineated as a distinct ovarian sex cord stromal tumor in 1973 by Chalvardjian and Scully. It is a benign neoplasm, distinguished from other ovarian stromal tumors by the production of collagen and a pseudolobular pattern, and it tends to occur in the second and third decades of life in diagnosed patients. We discovered two rare cases of SST in postmenopausal women which are the topic of this report. These case studies are accompanied by a brief review o...
Open Access DOI:10.23937/2377-9004/1410044
Fertility Sparing Surgery for Management of Serous Cystadenoma: Surgical Technique and Follow Up
Islam Fahmi, Mili Thakur, Ahmed Abdelaziz, Mohammed Ashraf and Mostafa I. Abuzeid
Article Type: Case Report | First Published: June 14, 2015
Ovarian cysts are commonly encountered adnexal masses by gynecologists, with a reported incidence of 5-15% of all reproductive age women. Large ovarian cysts are usually treated by surgical excision with cystectomy or oophorectomy. Laparoscopic ovarian cystectomy in large ovarian cysts has been underutilized. This report discusses the surgical technique of fertility sparing laparoscopic cystectomy for serous cystadenoma and subsequent follow up of these patients....
Open Access DOI:10.23937/2377-9004/1410043
Extensive Hemorrhage during C-section of a Placenta Percreta with Bladder Invasion - Case Report
Rodrigo Dias Nunes, Djulie Anne de Lemos Zanatta and Natalia Vidal Lucena
Article Type: Case Report | First Published: June 08, 2015
Morbidly Adherent Placenta is a clinical condition where the placental tissue implants abnormally to the myometrium. In rare situations, the placenta can pass through the myometrium and invade organs surrounding the uterus; this is referred to as Placenta Percreta. This high morbidity condition can lead to a massive hemorrhage during surgery along with other various complications. We report a case of a 35 year old woman with no previous diagnosis of Placenta Percreta. During C-section, extensive...
Open Access DOI:10.23937/2377-9004/1410042
Membranous Dysmenorrhea - Case Report
Rodrigo Dias Nunes and Viviane Cristine Pissetti
Article Type: Case Report | First Published: June 06, 2015
This is the report of a 32-year-old woman with severe abdominal pain followed by a decidual cast discharge. The Membranous Dysmenorrhea is a clinical entity rarely mentioned in the medical literature. Few discoveries have been made about this condition. The medical knowledge, due to the lack of description of this entity in current textbooks, also contributes to it's under diagnosis. The anatomopathological exam defines the diagnosis. These case reports are important to help to define the ideal ...
Open Access DOI:10.23937/2377-9004/1410041
Mayer-Rokitansky-Kuster-Hauser Syndrome - Case report
Rodrigo Dias Nunes and Djulie Anne de Lemos Zanatta
Article Type: Case Report | First Published: June 02, 2015
This is the report of a teenager student with primary amenorrhea with secondary sexual characteristics. The incidence of Mayer- Rokitansky-Kuster-Hauser syndrome was not clearly established, but studies indicate a variation of 1/4,000 and 1/5,000 live births of the female sex. The syndrome is characterized by aplasia of the Mullerian duct on a person who has karyotype 46, XX with female phenotype characteristic of primary amenorrhea in adolescence. Treatment is usually delayed until the patient ...
Open Access DOI:10.23937/2377-9004/1410040
Leiomyosarcoma of the Right Iliac Veins Presenting as a Pelvic Mass: A Case Report
E.Tripodi, V. Zanfagnin, C. Fava, P. Zola and A. Ferrero
Article Type: Case Report | First Published: May 30, 2015
Leiomyosarcoma of the iliac veins is a very uncommon tumour. Prognosis is usually poor and the best treatment is unknown. Case report: We report the case of a 74-year-old woman presenting a right leg oedema. Venous colour doppler was normal. Abdominal ultrasound and magnetic resonance scanning demonstrated a 70 mm mass in the right pelvis with a well-defined profile, which was not homogeneous after contrast enhancement....
Open Access DOI:10.23937/2377-9004/1410039
Long Term Triptorelin Therapy in a Large Endometriosis Nodule Arising in an Episiotomy Scar
Basma Darwish, Gregoire Leleup, Cecile Martin and Horace Roman
Article Type: Case Report | First Published: May 26, 2015
Endometriosis is the extra-uterine presence of endometrial glands and stroma, most often in the pelvis. It is very occasionally found in extra-abdominal sites. Perineal endometriosis is the presence of endometrial tissue in the perineal sites. Endometriosis of the perineum and vulva is extremely rare, with the most common site being episiotomy scars....
Open Access DOI:10.23937/2377-9004/1410038
The Gravid Patient Presenting with Laryngeal Angioedema
Luke Maxfield Jessica R Jackson and Julie Decesare
Article Type: Case Report | First Published: May 08, 2015
Laryngeal swelling can be life threatening with etiologies including angioedema and cellulitis. While both involve swelling of subcutaneous tissues angioedema involves extravasation of fluid into interstitium while cellulitis is caused by direct extension of a spreading infection. The cause of angioedema involves multiple etiologies with response to treatment varying with underlying pathophysiology....
Open Access DOI:10.23937/2377-9004/1410037
A Case of Arthrogryposis Multiplex Congenita in One Identical Twin Pregnancy
Ulas Fidan, Fahri Burcin Firatligil, Kazim Emre Karasahin, Mustafa Ulubay, Ugur Keskin and Ali Ergun
Article Type: Case Report | First Published: May 06, 2015
Arthrogryposis multiplex congenita, is a developmental deformation characterized with multiple joint contructures that is seen in one delivery out of 3000 in average. The limitation of fetal movements which start in early pregnancy weeks especially at the 7th or 8th gestastional week, is the most important factor in etiology....
Open Access DOI:10.23937/2377-9004/1410036
Case Report: 7q11 Microdeletion in Swyer Syndrome Patient
Patrick T Reeves, Axel G Moreira, Tochi M Amagwula, Toy G Lee, Dominique D Washington, AkilaMuthukumar and John Y Phelps
Article Type: Case Report | First Published: May 04, 2015
Swyer syndrome or XY gonadal dysgenesis is caused by genetic mutations in testis-determining factors, such as the SRY gene, that lead to streak gonads in phenotypical females. The following case demonstrates a patient with a 7q11 microdeletion, a region which governs the coding of a transcription regulator called Zinc Finger 92 (ZNF92)....
Open Access DOI:10.23937/2377-9004/1410035
Retained Placenta Accreta Presenting as Secondary Postpartum Hemorrhage
Yilun Koethe, Gabrielle A Rizzuto and Maureen P Kohi
Article Type: Case Report | First Published: May 02, 2015
Abnormal placentation and retention of products of conception (RPOC) are common causes of postpartum hemorrhage. Case: A 37-year-old gravida 4 para 1 woman with history of Asherman's syndrome from prior dilatation and curettage presented in spontaneous labor. Following normal vaginal delivery, portions of the placenta were retained and had to be manually extracted....
Open Access DOI:10.23937/2377-9004/1410034
Haemoglobin Electrophoretic Patterns, ABO and Rhesus D Blood Groups Distribution among Antenatal Women in Sokoto, Nigeria
Udomah FP, Isaac IZ, Aliyu N, Erhabor O, Ahmed MH, Yakubu A, Hassan M and John RT
Article Type: Research Article | First Published: April 23, 2015
All human red blood cells contain a pigmented metalloprotein called haemoglobin which is of different types. Hemoglobin is the oxygen carrying pigment of the red blood cells. Defects in its genes can produce abnormal haemoglobin which leads to conditions known as haemoglobinopathies. Haemoglobin electrophoretic patterns include the normal haemoglobin which is the most prevalent and is referred to as hemoglobin A (HbA) and other abnormal ones also exist, like hemoglobin S (HbS), which is a varian...
Open Access DOI:10.23937/2377-9004/1410033
Case Report on a 10cm Pelvic Mass: Unruptured Chronic Ectopic versus Neoplasm
Christine Rojas, Kerry Ann Hudson and Kevin Byrd
Article Type: Case Report | First Published: April 14, 2015
Ectopic pregnancy is the leading cause of maternal death in the first trimester. Approximately 18% of ectopic pregnancies present to the emergency department with vaginal bleeding, abdominal pain or both....
Open Access DOI:10.23937/2377-9004/1410032
Blasts on Blood Film after Treatment of Ovarian Cancer
Heong V, Duong B and Wong S
Article Type: Case Report | First Published: April 13, 2015
A 40 year old female with a history of hypertension, depression and menorrhagia was admitted with a one week history of flu like symptoms, lethargy and neutropenia. Two years prior to admission, she was diagnosed with FIGO Stage IIC clear cell epithelial ovarian cancer and underwent a total abdominal hysterectomy and bilateral salphingo-oophorectomy (optimal debulking)....
Open Access DOI:10.23937/2377-9004/1410031
Collision Tumor: Dermoid Cysts and Mucinous Cystadenoma in the Same Ovary and a Review of the Literature
Mehmet Suhha Bostanci, Ozge Kizilkale Yildirim, Gazi Yildirim, Murat Bakacak, Isin Dogan Ekinci, Sevgi Bilgen and Rukset Attar
Article Type: Case Report | First Published: March 31, 2015
Collision tumor is defined as the coexistence of two adjacent, but histologically distinct tumors without histological admixture in the same tissue or organ. Collision tumors involving ovaries are extremely rare. The coexistence of a mucinous cystadenoma with a dermoid cyst is infrequently reported. However, the most common histological combination of collision tumor in the ovary is the coexistence of teratoma with mucinous tumors....
Open Access DOI:10.23937/2377-9004/1410030
Hybrid Arc Stereotactic Ablative Body Radiation Therapy for Pelvic Relapse of Gynecologic Malignancies
Charles A Kunos, Howard Shaffer and Jeffrey M Fabien
Article Type: Case Report | First Published: March 30, 2015
Relapsed gynecologic cancers are difficult to control in the pelvis, especially when surgery, chemotherapy and radiation treatments have already been administered. For this clinical scenario, stereotactic body radiation therapy has emerged as a meaningful treatment strategy. The new Vero stereotactic body radiation therapy system uses coplanar and noncoplanar radiation treatment beams with submillimeter precision to treat cancer targets....
Open Access DOI:10.23937/2377-9004/1410029
Preventing E. coli O157:H7 Infection in Pregnancy
Bharati Kalgi and Mark G Martens
Article Type: Review Article | First Published: March 29, 2015
E. coli O:157 causes 73,000 illness in the United States annually. It is estimated that up to 10% of patients with EHEC infections may develop HUS, with a case-fatality rate ranging from 3% to 5%. Overall, HUS is the most common cause of acute renal failure leading to chronic renal sequelae in approximately 50% of survivors....
Open Access DOI:10.23937/2377-9004/1410028
Aortobifemoral Reconstruction during Pregnancy
Muller VA, Kasper AS and Hinterseher I
Article Type: Case Report | First Published: March 28, 2015
We report a case of aortobifemoral bypass because of severe peripheral artery disease in a 40-year-old woman at 13 weeks of pregnancy. The patient presented herself to the emergency room with necrosis on her toes and a reduction of her maximal walking distance. She was obese and a heavy smoker although she has been pregnant at that time....
Open Access DOI:10.23937/2377-9004/1410027
A Case Study of Stillbirth in a Pregnancy Complicated by Asthma
Vicki L Clifton and Maureen D Busuttil
Article Type: Case Report | First Published: March 25, 2015
Asthma during pregnancy can be complicated by intrauterine growth restriction, preterm delivery and stillbirth. This paper reports the obstetric and respiratory history of a 23 year old woman whose pregnancy was complicated by asthma and a severe asthma exacerbation that was associated with a stillbirth at 34 weeks gestation....
Open Access DOI:10.23937/2377-9004/1410026
The Evolution of Laparoscopy in the Management of the Ovarian Mass: Challenges Overcome, Challenges Remaining
Mohamad S Mahmoud
Article Type: Opinion | First Published: March 13, 2015
While laparotomy and ultrasound guided aspiration were still the common approaches for the management of ovarian cysts in the late 20th century, the introduction of laparoscopy in the surgical armatarium has begun changing this approach as early as the late 1960's. In his publication dated 1969, Dr Stepto from the royal college of obstetrics and gynecology describes his own techniques using laparoscopy to diagnose the type of the ovarian cyst by aspirating its content or by biopsy of the cysts i...
Open Access DOI:10.23937/2377-9004/1410025
Expectant Management in Cesarean Scar Pregnancy
Article Type: Letter | First Published: February 27, 2015
The incidence of pregnancy implantation at unusual sites like cesarean scar, cervix or ovaries is on rise due to the increase in incidence of cesarean sections, dilatation and curettages and pelvic inflammatory diseases. Diagnosis of these rare types of ectopic pregnancies is extremely challenging. Cesarean scar ectopic pregnancy as well as cervical pregnancy can be easily confused with each other or with an inevitable abortion....
Open Access DOI:10.23937/2377-9004/1410024
The Outcome of TVT-O Procedure with Cough Test in Theatre under Local Anaesthesia and Sedation in Women with or without Intrinsic Sphincter Deficiency: Retrospective Case Series of 111 Women
Nader Gad, Basia Slusarczyk, Brooke O'Brien and Andrew Mitchell
Article Type: Case Report | First Published: February 23, 2015
Aim: To assess the outcome of TVT-O procedure performed under local anaesthesia and sedation, with a cough test, on patients with urodynamic stress urinary incontinence with or without intrinsic sphincter deficiency. Methods: A retrospective cohort study analysing the outcomes of 111 women between December 2004 and April 2013. The primary outcome was the resolution of stress urinary incontinence....
Open Access DOI:10.23937/2377-9004/1410023
Uterine Artery Embolisation for the Treatment of Large Submucosal Fibroid (Clinical Case)
Dobrokhotova J, Grishin I, Khachatryan A, Causeva O, Zlatovratsky A and Rogovskaya S
Article Type: Case Report | First Published: February 09, 2015
Article is devoted to the problem of endovascular treatment of uterine fibroids - Uterine Artery Embolization (UAE). A number of researches do not promote to use UAE technique when the uterine fibroid has submucosal position, considering the conservative transcervical myomectomy to be more accessible. In the article, based on clinical case, indication of EMA at the large submucous uterine fibroid among women that are still in their reproductive age as an alternative to a hysterectomy is discusse...
Open Access DOI:10.23937/2377-9004/1410022
Intra-operative Management of Skull Remnant Discovered during Emergent Primary Cesarean Delivery
Lisa A. Licare and Suruchi Thakore
Article Type: Case Report | First Published: February 08, 2015
Background: Operative anticipation of patients with prior abdominal surgeries is critical for the evaluation of obstetric patients. The following case demonstrates the importance of preoperative planning before emergent surgery is indicated. Case: T.M. is a 26 year- old gravida 8, para 0161 at 24 weeks 5 days who presented with preeclampsia with severe features. Her history is significant for brain surgeries with abdominal skull flap preservation. She required an emergent cesarean where a skull ...
Open Access DOI:10.23937/2377-9004/1410021
Arteriovenous Malformation of the Cervix: A Rare Cause of Vaginal Bleeding after Supracervical Hysterectomy
Nigel Pereira, Kayla M Wishall, Gabrielle M Hawkins, Nima R. Patel and Carl R. Della Badia DO
Article Type: Case Report | First Published: January 30, 2015
Background: Cyclic vaginal bleeding is a well-known complication after a supracervical hysterectomy; however, severe delayed vaginal bleeding occurs infrequently. Case: A 29-year-old woman underwent a supracervical hysterectomy for dysmenorrhea and pelvic pain refractory to multiple medical modalities. Eight weeks after surgery, the patient began to experience persistent heavy vaginal bleeding that continued in spite of application of silver nitrate to the cervical stump. The patient subsequentl...
Open Access DOI:10.23937/2377-9004/1410020
Endoscopic Conservative Treatment for an Ureterovaginal Fistula Caused by Foreign Body
DeLeon E, Lankford D, Allman D, Phillibert D, Paolucci M, Gore S and Clare C
Article Type: Case Report | First Published: January 20, 2015
Foreign body placement in the vagina is a rare cause of ureterovaginal fistula. A fistula is often due to an unrecognized injury to the ureter, most commonly after gynecologic pelvic surgery, such as during hysterectomy for benign indications. This manuscript will discuss a case of a 34-year-old African American female who presents with a history of sexual assault and a one month history of urinary incontinence. Physical examination revealed clear liquid in the vaginal vault and a malodorous for...
Open Access DOI:10.23937/2377-9004/1410019
Conservative Management of Uterine Artery Pseudoaneurysm Rupture with Rectal Fistula after Laparoscopic Myomectomy and Review of the Literature
Gabbi L, Petrocelli F, Di Domenico S, Ferrero S and RemorgidaV
Article Type: Case Report | First Published: December 17, 2014
Late uterine hemorrhage caused by uterine artery pseudoaneurysm is a rare but life-threatening complication after uterine surgery. The association of uterine pseudoanerysm rupture causing rectal fistula has not been reported in literature as well as its management. Herein we report a case of massive late uterine bleeding and rectal bleeding after laparoscopic myomectomy. A 43 year old Caucasian nulliparous woman underwent laparoscopic excision of 8 cm posterior intramural myoma. One month later ...
Open Access DOI:10.23937/2377-9004/1410018
Management of Early Pregnancy Failure in a Patient with Pancytopenia
Diana Cholakian and Jenell Coleman
Article Type: Case Report | First Published: December 08, 2014
The safest and most effective therapy for an early pregnancy failure in women with pancytopenia is unknown. Here, we present a case report of a patient diagnosed with a 10-week embryonic demise who had a rare hematologic disorder called TnPolyagglutination syndrome that caused pancytopenia. The patient was offered expectant, medical, or surgical management, and she chose outpatient vaginal misoprostol. A week later, the patient presented to the emergency room with a septic abortion. She was give...
Open Access DOI:10.23937/2377-9004/1410017
Is Single Incision Laparoscopy A Feasible Alternative for Advanced Ovarian Cancer Approach? A Case Report and Literature Review
Marina Fistarol, Paula Guastaferro Magalhaes, Paola Gaston Giostri, Admario Silva Santos Filho, Augusto Henriques Fulgencio Brandao and Mauricio Bechara Noviello
Article Type: Case Report | First Published: December 08, 2014
Single Incision Laparoscopy (SIL) is a promising technique in the context of minimally invasive surgery, since it might improve cosmesis and cause less tissue trauma, if compared to multiple incision laparoscopies. Recent studies have shown its feasibility and safety for the approach of benign diseases. In this article, we report four cases of advanced ovarian cancer, addressed through SIL, with the purpose of fast diagnosis and recovery, allowing prompt onset of chemotherapy....
Open Access DOI:10.23937/2377-9004/1410016
An Unusual Cause of Transıent Fetal Ascıtes: Fetal Ovarıan Cyst Rupture
Article Type: Case Report | First Published: December 07, 2014
Background: Ovarian cysts can be diagnosed prenatally and in case of persistence are found in newborns. Most resolve spontaneously, although in a small proportion of cases they can persist and be symptomatic. Fetal ascites may be due to immune or non immune hydrops fetalis or to a series of locoregional problems However, it can be an isolated finding rarely. Case: In this case we reported an isolated fetal ascites case that was caused by fetal ovarian cyst rupture. Conclusion:Fetal hydrops may b...
Open Access DOI:10.23937/2377-9004/1410015
Angular Pregnancy: A Review of Cases Reported in the Past 80 Years
Michael Brett Rankin, Allison Dunning BS and Elizabeth Kagan Arleo
Article Type: Review Article | First Published: December 06, 2014
Objective: To review reported cases of angular pregnancy (defined in 1898 as "implantation of the embryo just medial to the uterotubal junction, in the lateral angle of the uterine cavity") to determine outcomes. Study design: A systematic search of medical electronic databases (1934-2013; search term: "angular pregnancy") was performed, initially yielding 150 manuscripts; after application of selection criteria, 54 were included for review, yielding 85 cases of angular pregnancy. Pregnancy outc...
Open Access DOI:10.23937/2377-9004/1410014
An Uncommon Case of Antepartum and Postpartum Surgical Aorta Repair in a Patient with Marfan Syndrome
Liggins Casandra A, Lin Monique G and Foley Michael R
Article Type: Case Report | First Published: November 30, 2014
Background: Marfan syndrome is a heritable connective tissue disorder with significant risk of cardiovascular compromise. The physiological changes of pregnancy greatly increases that risk resulting in significant threat of maternal and fetal morbidity and mortality. Case: A 21-year-old G1P0 female with Marfan syndrome presented at 16 weeks gestation with a 7.3 cm ascending aortic aneurysm and a desire to maintain her pregnancy. Immediate surgical repair was performed upon presentation with reas...
Open Access DOI:10.23937/2377-9004/1410013
Paraganglioma and Pregnancy: Management of Cesarean Delivery and Subsequent Laparoscopic Adrenalectomy
Jennifer T. Mallek, Monique Ho, Christiana Shaw, Mark Rice and Tammy Euliano
Article Type: Case Report | First Published: November 30, 2014
Background: Pheochromocytomas and paragangliomas are rare catecholamine-secreting tumors (CSTs) that may lead to severe hypertensive episodes and are associated with high maternal and fetal mortality when undiagnosed or mismanaged. Case: A 28-year-old full-term, normotensive woman with presumed pheochromocytoma underwent a cesarean under epidural anesthesia, which was also used for postoperative pain control, followed by an uncomplicated adrenalectomy under general anesthesia 5 days later....
Open Access DOI:10.23937/2377-9004/1410012
Case Report of Massive Subcutaneous Emphysema: A Benign Postoperative Finding
Jonathan R. Foote, Matthew F. Kohler and Jennifer Young-Pierce
Article Type: Case Report | First Published: November 29, 2014
The development of postoperative crepitus following abdominal surgery is not a normal physical exam finding and should prompt an immediate concern for necrotizing fasciitis. Imaging using Computed Tomography (CT) will demonstrate subcutaneous emphysema. This case report presents a patient with benign postoperative surgical subcutaneous emphysema presenting as crepitus on exam. A 44-year-old female presented with a large uterine firoid with concerns for sarcomatous growth given dramatic short int...
Open Access DOI:10.23937/2377-9004/1410011
Neoadjuvant Chemotherapy for Vulvar Cancer: Case Series from a Single Institution
Ismail Mert, Jacqueline Guterman, Ira S. Winer, Rouba Ali-Fehmi and Gunter Deppe
Article Type: Case Report | First Published: November 27, 2014
Vulvar carcinoma accounts for approximately 5% of gynecologic cancers in the United States with an estimated 4,490 new cases and 950 deaths in 2012. Survival depends on the extent of cancer spread upon initial diagnosis. Th staging of vulvar cancer depends on tumor size and spread to lymph nodes and other organs. Stage I and II comprise the early stages of vulvar carcinoma, where there is localized disease without lymph node involvement. Whereas late stage disease, stage III and IV, involves tum...
Open Access DOI:10.23937/2377-9004/1410010
Staged Management of Placenta Accreta in a Hybrid Operating Room Suite
Valerie E Whiteman, Bruce Zweibel, Amrat Amand, Mary A Cain, Xiaomang Stickles and Mitchel Hoffman
Article Type: Case Report | First Published: November 17, 2014
Background: The proper management of placenta accreta remains challenging, with risks of significant blood loss. Interventional radiology assistance for control of hemorrhage is considered for difficult cases however this involves transportation of a critically ill patient. Case: We performed a multi-step cesarean hysterectomy for placenta accreta in a hybrid operating room suite. With intra-arterial catheters placed pre-operatively, the cesarean was performed leaving the placenta in utero, with...
Open Access DOI:10.23937/2377-9004/1410009
Comparative Genomic Hybridization (CGH) for Prenatal Diagnosis of Wolf-Hirschhorn Syndrome
Adara Benitez, Marina Naveiro, Manuel Vargas, Maria Setefila Lopez-Criado, Carmen Entrala and Sebastian Manzanares
Article Type: Original Article | First Published: November 17, 2014
Wolf-Hirschhorn Syndrome (WHS) is a rare genetic condition caused by partial deletion of the short arm of chromosome 4 (4p-). Variability in 4p deletions and rearrangements leads to a wide spectrum of clinical manifestations of this disease. Most prenatal WHS diagnoses are associated with large 4p deletions identified by conventional cytogenetic techniques; however some submicroscopic deletions can only be diagnosed using molecular techniques. In this case report, a combined diagnostic approach ...
Open Access DOI:10.23937/2377-9004/1410008
Laparoscopic Management of Bilateral Large Ovarian Cysts in a Young Female
M. Brigid Holloran-Schwartz, Jacqueline F. Lou and Leslie McCloskey
Article Type: Case Report | First Published: November 15, 2014
Adnexal masses are a common finding in women of all ages, with a 5-10% lifetime risk of surgery for suspected ovarian neoplasms. The most common symptoms of ovarian cysts are pelvic pressure or pain, however many can remain asymptomatic. Ovarian cancer risk increases in a linear fashion between the ages 30 and 50, with this risk continuing to increase, although at a slower rate, after the age of 50. While age is the largest risk factor for ovarian cancer, the combined history and physical findin...
Open Access DOI:10.23937/2377-9004/1410007
Successful Outcome of an Uneventful Caesarean Scar Pregnancy with Intra-Ligamentary Development
Akladios Cherif Y and Langer Bruno
Article Type: Case Report | First Published: November 15, 2014
A 33-year-old woman, gravida 5, para 2, was scheduled for a caesarean delivery at 38 weeks, because of both the foetus's breech presentation and her history of 2 caesarean deliveries. A subsequent dilatation and curettage for incomplete abortion completed her obstetric history. Early pregnancy was uneventful. Ultrasound at 6 and 8 weeks showed a viable and apparently normally situated embryo. During the second and third trimester, fetal growth and Doppler waveforms were within normal limits, and...
Open Access DOI:10.23937/2377-9004/1410006
Ovarian Cancer in Early Pregnancy, an Unusual Presentation
Saniya M Eltayeb, Moza A AlKalbani, Sarah O Abu Zaid and Saba Mubbashir
Article Type: Case Report | First Published: November 13, 2014
The incidence of diagnosed ovarian carcinoma in pregnancy is rare, reported as 0.018-0.073/1000 pregnancies. Very few cases are reported in the English literature regarding management of ruptured malignant ovarian cyst in pregnancy; almost all the cases reported described patients in the third trimester of pregnancy. We report a case of a young female who presented with acute abdomen at seven weeks gestation and was found to have an ovarian malignancy....
Open Access DOI:10.23937/2377-9004/1410005
Knowledge and Attitude of Nurses towards In-vitro Fertilization: A Prospective Cohort Study
Obioha Joy A, Ikechebelu Joseph I, Eleje George Uchenna and Joe-Ikechebelu Ngozi N
Article Type: Research Article | First Published: October 29, 2014
Caesarean scar pregnancy (CSP) is the rarest type of ectopic pregnancy. It is a life-threatening abnormal form of implantation of a gestational sac in the myometrium at the site of a previous Caesarean scar. CSP was fist described by Larsen and Salomon in 1978. It is estimated that CSP constitutes about 6% of all ectopic pregnancies in patients with a history of at least one Caesarean section. Th incidence of this pathology ranges from 1/1800 to 1/2200 pregnancies and its rate is 0.15% in women ...
Open Access DOI:10.23937/2377-9004/1410004
Klinefelter's Syndrome in an Adolescent
Eleje George Uchenna and Ikechebelu Joseph Ifeanyichukwu
Article Type: Case Report | First Published: October 31, 2014
Klinefelter's syndrome is an important common sex chromosomal abnormality in humans and it remains an important genetic cause of male infertility. A 12-year-old student was referred to our hospital due to presence of small penis and testes since birth and progressive breast enlargement of fie years duration. On examination, the height was 1.64 metres and weight was 75kg. Breasts and axillary hairs were well developed at Tanner stage IV and III respectively and hair distribution of external genit...
Open Access DOI:10.23937/2377-9004/1410003
Bilateral Uterine Artery Chemoembolization with Methotrexate and Gelatine Foam for Caesarean Scar Pregnancy - Case Report
Krzysztof Pyra, Slawomir Wozniak, Piotr Czuczwar, Piotr Szkodziak and Michał Sojka
Article Type: Case Report | First Published: October 29, 2014
Caesarean scar pregnancy (CSP) is the rarest type of ectopic pregnancy. It is a life-threatening abnormal form of implantation of a gestational sac in the myometrium at the site of a previous Caesarean scar. CSP was fist described by Larsen and Salomon in 1978. It is estimated that CSP constitutes about 6% of all ectopic pregnancies in patients with a history of at least one Caesarean section. Th incidence of this pathology ranges from 1/1800 to 1/2200 pregnancies and its rate is 0.15% in women ...
Open Access DOI:10.23937/2377-9004/1410002
An Incidental Diagnosis of the Cystadenofibroma of the Ovary in the Cesarean Section: A Case Report
Hasan Onur Topcu, Zeynep Aslı Oskovi, Ali Irfan Guzel, Irfan Ozer, Mahmut Kuntay Ko kanali and Sabri Cavkaytar
Article Type: Case Report | First Published: October 27, 2014
Ovarian cystadenofibromas are relatively rare epithelial ovarian tumors which contain fibrous stroma besides the epithelial proliferation. They may mimic malignant neoplasms with their gross appearance or by imaging modalities. In our case, an incidental ovarian mass was detected in a 41 year-old patient during cesarean section with an appearance like a malignant tumor. We did not have the chance for frozen-section diagnosis because the emergency cesarean section was performed in night shift con...
Open Access DOI:10.23937/2377-9004/1410001
Outcome of Labor in Twin Gestation at a Tertiary Institution in a Developing Nation: A 15-Year Review
Rose Anorlu and Olukayode Akinlaja
Article Type: Review Article | First Published: September 19, 2014
Objective: To describe our experience with twin gestation in a developing nation tertiary institution. Method: All cases of twin gestation at the Lagos University Teaching Hospital over a 15-year period were retrospectively reviewed. Results: There were 642 twin births out of a total of 28,472 deliveries, a ratio of 1:44. Peak age at occurrence was 28 with only 6% (39) being grand multipara. 66.4% (426) delivered preterm at about 36 weeks and 74.5% (478) had the leading twin in cephalic pres...
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ClinMed Journals Index Copernicus Values
Clinical Medical Image Library: 93.51
International Journal of Critical Care and Emergency Medicine: 92.83
International Journal of Sports and Exercise Medicine: 91.84
International Journal of Womens Health and Wellness: 91.79
Journal of Musculoskeletal Disorders and Treatment: 91.73
Journal of Geriatric Medicine and Gerontology: 91.55
Journal of Infectious Diseases and Epidemiology: 91.55
Clinical Medical Reviews and Case Reports: 91.40
International Archives of Nursing and Health Care: 90.87
International Journal of Ophthalmology and Clinical Research: 90.80
International Archives of Urology and Complications: 90.73
Journal of Clinical Nephrology and Renal Care: 90.33
Journal of Family Medicine and Disease Prevention: 89.99
Journal of Clinical Gastroenterology and Treatment: 89.54
Journal of Dermatology Research and Therapy: 89.34
International Journal of Clinical Cardiology: 89.24
International Journal of Radiology and Imaging Technology: 88.88
Obstetrics and Gynaecology Cases - Reviews: 88.42
International Journal of Blood Research and Disorders: 88.22
International Journal of Diabetes and Clinical Research: 87.97