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ClinMed International Library

For the past decade, ClinMed International Library has been at the forefront of publishing cutting-edge research in clinical medicine. Over the last 10 years, we have consistently provided a platform for publishing innovative findings and advancements in medical science.

The ClinMed International Library is a repository and an open access publisher for medical research that covers a wide range of areas in Clinical Medicine. ClinMed serves as a global platform for medical practitioners and research scholars to foster their learning and professional acumen through an extensive portfolio of research articles and publications that can be accessed without any restrictions.

Dedicated to clinical medical research, we now publish over 70 quality peer-reviewed journals making all the articles freely accessible. The manuscripts submitted to ClinMed will be processed through standard parameters and international peer review systems. This has enabled us to establish new milestones in the global research arena in terms of cogency and integrity, and to disseminate highly credible and accredited research content for researchers, scholars, and practitioners across the globe.

We ensure that all researchers and authors publishing their papers with us retain copyrights, licensed under Creative Commons Attribution License that permits the unrestricted use and re-use of the content with proper citation.


  Last Updated: June 29, 2024
Articles Search by   Keyword   |   Journal title   |   Author name   |   DOI

 Open Access DOI:10.23937/2378-3656/1410058

The Challenge of Infections in Frail Elderly: The Story of Mr. Nilsson

Sund-Levander M and Grodzinsky E

Article Type: Case Report | First Published: September 26, 2015

Signs and symptoms of infection in Nursing Home Residents (NHR) are often atypical with a lack of specific ones, causing a delay in diagnosis and treatment. The complexity of detecting infections in NHR can be explained by difficulties in understanding and interpreting non-specific signs and symptoms and co-existing chronic diseases that blur the clinical picture. The case of Mr. Nilsson illustrates the process from the first signs and symptoms of infection to diagnosis in an elderly person with...

 Open Access DOI:10.23937/2378-3419/2/4/1028

Targeting of Myeloid Derived Suppressor Cells Using Anti-inflammatory and Pro-inflammatory Agents

Parvin Forghani and Edmund K Waller

Article Type: Review Article | First Published: October 03, 2015

Myeloid-derived suppressor cells (MDSC) have been considered to be key mediators of immuno-suppression in cancer. The numbers of MDSCs increased in the blood and in the tumor microenvironment during inflammation. Due to the strong correlation between inflammation and cancer that results in tumor progression through MDSCs-associated immune-suppression, it is posited that modulating MDSCs using anti-inflammatory drugs will enhance the activity of immunotherapy and antitumor immunity....

 Open Access DOI:10.23937/2378-3419/2/4/1027

Metastatic Squamous Cell Carcinoma of the Neck from Unknown Primary Sites: the Ottawa Regional Cancer Centre (ORCC) Experience

Osama Marglani, Ameen Zaid Alherabi, Ali Safar, Suliman Alghamdi, Libni Eapen, Helen Caetano and Martin Corsten

Article Type: Original Research Article | First Published: September 25, 2015

Metastatic squamous cell carcinoma (SCC) to the neck from an unknown primary site presents a challenging diagnostic and therapeutic disease entity, despite a thorough diagnostic workup. The optimal management of patients who have this syndrome is still unclear and controversial. We present our experience in management of patients with unknown primary....

 Open Access DOI:10.23937/2378-3419/2/4/1026

Systematic Review and Meta-Analysis to Determine the Optimum Staging modality for Primary Breast Cancer

Berney M, Manning A, Carter M, Sacchini V, Kell M R. Barry M

Article Type: Original Article | First Published: September 24, 2015

Staging of primary breast cancer can radically alter the management if stage IV disease is accurately detected. A systematic review and meta-analysis were performed to determine whether conventional CT TAP or PET-CT provides the optimum staging modality. A meta-analysis involving 158 patients with primary breast cancer showed that PET-CT was more sensitive than CT-TAP for detection of metastatic disease (OR 3.28, 95% CI 2.37 - 4.53, p < 0.0001). A systematic review of 1780 patients undergoing PE...

 Open Access DOI:10.23937/2378-3419/2/4/1025

Common Polymorphisms in the USF1 Gene and Cancer Susceptibility: A Meta-Analysis

Meng Zhang, Jian Bai1, Junjie Huang, Yukun Ge, Hu Xiong, Wei Lu, Jizhou Shi, Lu Fang, Song Wu and Zhiming Cai

Article Type: Original Article | First Published: September 21, 2015

Upstream transcription factor 1(USF1) has been identified to be implicated in the development of many cancer categories. In view of recent studies, several polymorphisms in USF1 gene appeared to exert diverse influence on cancer susceptibility. However, the association between USF1 polymorphisms and cancer susceptibility remains inconclusive due to the finite relevant published discoveries. Therefore, we conducted a meta-analysis by pooling all available published data on the susceptibility of U...

 Open Access DOI:10.23937/2469-570X/1410011

Potential Immune Modulatory Action of Mesenchymal Stem Cell-Derived Extracellular Vesicles in Type 1 Diabetes

Andrea Carpanetto, Chiara Gai, Enrica Favaro, Maria Maddalena Zanone and Giovanni Camussi

Article Type: Short Review | First Published: September 28, 2015

Several preclinical studies have shown potential immune-modulatory properties of mesenchymal stem cells (MSC) in type 1 diabetes leading to phase I/II clinical trials. Immune-modulatory properties of MSC have been mainly ascribed to their secretome. The extracellular vesicles (EV) have emerged as paracrine mediators of MSC actions. In fact, MSC-derived EV have been shown to carry proteins and nucleic acids capable to mimic the effect of originating cells. In the present short review we discuss e...

 Open Access DOI:10.23937/2469-5831/1510006

Noise Analysis of Gene Regulatory Networks Using Particle Filter

Haixin Wang and Dawit Aberra

Article Type: Original Article | First Published: October 03, 2015

One of the most important properties in gene expression is the stochasticity. Gene expression process is noisy and fluctuant. In this paper, the noise of gene regulatory networks (GRNs) using polynomial model and S-system model is analyzed by proposed approach on the basis of particle filter. The measurement noise and process noise are analyzed to test noise effects on the synthetic GRNs. The relation among Root Mean Square (RMS) error, measurement noise, and system noise covariance is analyzed....

 Open Access DOI:10.23937/2469-5726/1510022

Lupus-Associated Pancreatitis: Clinical Aspects

Maria Helena Favarato

Article Type: Review Article | First Published: September 28, 2015

Systemic lupus erythematosus (SLE) is a systemic autoimmune inflammatory disease, with several different clinical manifestations. Its annual incidence is about 5 cases per 100000 inhabitants. The prevalence is around 52 cases per 100000 inhabitants. The gastrointestinal tract may be affected, either by the disease itself or by adverse reactions of medications or by opportunistic infections. Although common, the incidence of gastrointestinal manifestations may be underestimated, as the symptoms m...

 Open Access DOI:10.23937/2469-5726/1510021

Eosinophilic Fasciitis Treated with Tocilizumab: Demonstration of Efficacy after Withdrawal and Re-Challenge in a Patient

Glen T D Thomson, Janine L Johnston and Brent R J Thomson

Article Type: Case Report | First Published: September 28, 2015

A 41-year-old man presented with clinical features of eosinophilic fasciitis (EF) confirmed on biopsy. The patient responded to high-dose prednisone but subsequent steroid sparing medication including methotrexate, hydroxychloroquine, etanercept, golimumab and rituximab failed to deliver steroid sparing response. Tocilizumab provided rapid and sustained improvement in the patient's symptoms and signs. Withdrawal of tocilizumab resulted in a flare of the clinical manifestations of EF; retreatment...

 Open Access DOI:10.23937/2469-5726/1510020

A Case of Rhabdomyolysis and Polyarticular Inflammatory Arthritis May be the Initial Presentation of Chronic Myelogenous Leukemia (CML)

Yelliann Ruiz-Irizarry and Petros Efthimiou

Article Type: Case Report | First Published: September 24, 2015

Rhabdomyolysis and inflammatory arthritis are common rheumatologic conditions that manifest in people of all ages. Proximal muscle weakness associated to rhabdomyolysis is frequently the initial presentation of inflammatory myopathies such as dermatomyositis (DM) and polymyosistis (PM) both, extensively described in literature to be related to paraneoplastic process. Inflammatory arthritis has been associated to certain paraneoplastic syndromes, but not in relation to Chronic Meylogenous Leukemi...

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Partnered with ICI World of Journals. Check the Index Copernicus Values of ClinMed Journals

ClinMed Journals Index Copernicus Values

Clinical Medical Reviews and Case Reports: 91.40

International Archives of Nursing and Health Care: 90.87

International Journal of Sports and Exercise Medicine: 91.84

Obstetrics and Gynaecology Cases - Reviews: 88.42

International Journal of Womens Health and Wellness: 91.79

Journal of Musculoskeletal Disorders and Treatment: 91.73

Journal of Geriatric Medicine and Gerontology: 91.55

Journal of Infectious Diseases and Epidemiology: 91.55

International Journal of Clinical Cardiology: 89.24

Journal of Dermatology Research and Therapy: 89.34



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New Issues

VOLUME 10

International Journal of Clinical Cardiology

ISSN: 2378-2951 | ICV: 89.24

VOLUME 10
VOLUME 10

Obstetrics and Gynaecology Cases - Reviews

ISSN: 2377-9004 | ICV: 88.42

VOLUME 10
VOLUME 9

Journal of Hypertension and Management

ISSN: 2474-3690 | ICV: 87.69

VOLUME 9
VOLUME 10

International Journal of Diabetes and Clinical Research

ISSN: 2377-3634 | ICV: 87.97

VOLUME 10
VOLUME 9

Journal of Infectious Diseases and Epidemiology

ISSN: 2474-3658 | ICV: 91.55

VOLUME 9

Featured Articles

Right Ventricular Mass: A Unique Approach to Tissue Diagnosis

Bistees George, MD, Marina Sharif, MD, Rishi Bolla, BS, Shaheen Muhammad, MD and Stephen Cook, MD

DOI: 10.23937/2378-2951/1410285



Cyclopia, A Rare Congenital Malformation: A Case Report in a Resource-Limited Setting in Sub-Saharan Africa

Therence N. Dingana, Carlson Sama, Nuh T. Zeh, Herbert Fonteh, Achuasah M. Tah-Atam and Gloria Ashuntantang

DOI: 10.23937/2378-3656/1410435



LigaSure for Management of Obstructed Hemivagina with Ipsilateral Renal Anomaly (OHVIRA) Syndrome

Haven Nicole Frazier, DO and Glendell de Guzman, MD

DOI: 10.23937/2377-9004/1410248


Featured Journals

Clinical Medical Reviews and Case Reports Editor-in-chief: Prof. Wei Wang

International Journal of Surgery Research and Practice Editor-in-chief: Prof. Brian Richard Davis

International Journal of Stem Cell Research & Therapy Editor-in-chief: Prof. Faris Farassati

International Journal of Clinical Cardiology Editor-in-chief: Prof. Breijo-Marquez

Journal of Genetics and Genome Research Editor-in-chief: Prof. Ming Zhan

Obstetrics and Gynaecology Cases - Reviews Editor-in-chief: Prof. Leslie Iffy

International Journal of Cancer and Clinical Research Editor-in-chief: Prof. Sulma I Mohammed

International Journal of Diabetes and Clinical Research Editor-in-chief: Prof. Masayoshi Yamaguchi

International Journal of Anesthetics and Anesthesiology Editor-in-chief: Prof. Ike Eriator

International Journal of Respiratory and Pulmonary Medicine Editor-in-chief: Prof. Shufeng Zhou

International Journal of Sports and Exercise Medicine Editor-in-chief: Prof. J David Prologo

Journal of Rheumatic Diseases and Treatment Editor-in-chief: Prof. Bruce M Rothschild

International Archives of Urology and Complications Editor-in-chief: Prof. Ajay Singla

International Journal of Psychology and Psychoanalysis Editor-in-chief: Prof. Joaquim JF Soares

Journal of Obesity and Weight-loss Medication Editor-in-chief: Prof. Timothy Koch

Trauma Cases and Reviews Editor-in-chief: Prof. William Min

Clinical Medical Image Library Editor-in-chief: Prof.

International Journal of Transplantation Research and Medicine Editor-in-chief: Prof. Lydia M Petrovic

Journal of Otolaryngology and Rhinology Editor-in-chief: Prof. John E. Nathan

Journal of Geriatric Medicine and Gerontology Editor-in-chief: Prof. Ryuichi Morishita

International Journal of Critical Care and Emergency Medicine Editor-in-chief: Prof. Yasushi Shibata

International Journal of Womens Health and Wellness Editor-in-chief: Prof. Erich Cosmi

International Journal of Brain Disorders and Treatment Editor-in-chief: Prof. Terry Lichtor

International Journal of Clinical Biostatistics and Biometrics Editor-in-chief: Prof. James Michael Hardin