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ClinMed International Library

The ClinMed International Library is a repository and an open access publisher for medical research that covers a wide range of areas in Clinical Medicine. ClinMed serves as a global platform for medical practitioners and research scholars to foster their learning and professional acumen through an extensive portfolio of research articles and publications that can be accessed without any restrictions.

Dedicated to clinical medical research, we now publish over 70 quality peer-reviewed journals making all the articles freely accessible. The manuscripts submitted to ClinMed will be processed through standard parameters and international peer review systems. This has enabled us to establish new milestones in the global research arena in terms of cogency and integrity, and to disseminate highly credible and accredited research content for researchers, scholars, and practitioners across the globe.

We ensure that all researchers and authors publishing their papers with us retain copyrights, licensed under Creative Commons Attribution License that permits the unrestricted use and re-use of the content with proper citation.


  Last Updated: March 23, 2023
Articles Search by   Keyword   |   Journal title   |   Author name   |   DOI

 Open Access DOI:10.23937/2378-3672/1410014

Inflammatory Cell Markers in Local Allergic Rhinitis

Senol Comoglu, Ece Comoglu, M. Nesil Keles and Kemal Deger

Article Type: Original Article | First Published: November 06, 2015

Idiopathic rhinitis (IR), previously referred to as 'intrinsic rhinitis' or 'non-allergic perennial rhinitis', is a form of rhinitis that occurs without a known predisposing factor. In fact, IR is a subtype of non-allergic non-infectious rhinitis; the pathophysiology of IR has not been completely elucidated. Negative skin-prick test (SPT) along with the classical symptoms at the time of presentation may lead to misdiagnosis of vasomotor rhinitis. However, vasomotor rhinitis is a form of non-alle...

 Open Access DOI:10.23937/2378-3672/1410013

Immunobiology of S100A8 and S100A9 Proteins and Their Role in Acute Inflammation and Sepsis

Mohamed Elgazzar

Article Type: Review Article | First Published: October 16, 2015

During the stress-mediated response to infection and tissue injury, their levels markedly increase and contribute to acute and chronic inflammatory disorders as cell autonomous and non-autonomous activators of toll-like receptors (TLRs). There is controversy, however, whether S100A8 and S100A9 are pathogenic or protective during infection and inflammation. Some studies suggest that S100A8 and S100A9 proteins function extracellularly to amplify TLR-mediated responses, thereby increasing inflammat...

 Open Access DOI:10.23937/2474-3674/1510009

High Flow Conditioned Oxygen Therapy for Prevention of Reintubation in Critically Ill Patients: A Preliminary Cohort Study

Gonzalo Hernandez, Concepcion Vaquero Collado, Susana Garcia Plaza, Ana Villasclaras Pacheco, Candido Pardo Rey, Eugenia de la Fuente O'Connor, Rafael Cuena, Paloma Gonzalez Arenas, Rafael Fernandez

Article Type: Original Research Article | First Published: December 31, 2015

Oxygen delivery after extubation is the cornerstone treatment to maintain adequate oxygenation and avoid reintubation. Oxygen is usually delivered through low-flow nasal prongs; when necessary, flow is increased or patients are switched to a high-flow face mask. Some other interventions after extubation focus on specific causes of reintubation; for example, high risk patients are administered prophylactic corticosteroids before planned extubation to prevent laryngeal edema and patients with hype...

 Open Access DOI:10.23937/2474-3674/1510008

Relationship Between Isolating Multi-Drug Resistant A. Baumannii and K. Pneumoniae in Bronchial Aspirate and Subsequently in Blood Cultures: Evaluation of Colistin Aerosol Therapy in Intensive Care Patients

Distasi Maria Antonietta, Del Gaudio Tito, Malcangi Annarita and Pirronti Angela

Article Type: Research Article | First Published: December 30, 2015

Klebsiella pneumoniae (K. pneumoniae) and Acinetobacter baumannii (A. baumannii) are multiresistant pathogens most frequently found in patients hospitalized in the Intensive Care of our hospital. We found the highest rate of positivity in the bronchial aspirates, often followed by a similar observation in blood culture. We carried out a study to evaluate the reduction of sepsis that developed after the detection of these microorganisms in bronchial aspirate, following the introduction of treatme...

 Open Access DOI:10.23937/2469-570X/1410021

A Conceptual Integration of Extra-, Intra- and Gap Junctional- Intercellular Communication in the Evolution of Multi-cellularity and Stem Cells: How Disrupted Cell-Cell Communication during Development can Affect Diseases later in Life

James E Trosko

Article Type: Review Article | First Published: January 29, 2016

An attempt will be made to provide a short conceptual review to integrate, from an evolutionary perspective, how the emergence of gap junctional intercellular communication helped to bring about multi-cellularity and new adaptive phenotypes. This new fundamental biological function of the metazoans was needed to provide homeostatic control of new cellular functions of an interacting society of different cell types existing in a 3-dimensional unit. Changing paleo-physics- and -chemistry of the ea...

 Open Access DOI:10.23937/2469-570X/1410020

Hypophosphatasia and Mesenchymal Stem Cells: A Therapeutic Promise

Maria Teresa Valenti, Luca Dalle Carbonare and Monica Mottes

Article Type: Review Article | First Published: January 29, 2016

Hypophosphatasia (HPP) is due to mutations in ALPL gene which encodes the tissue non-specific alkaline phosphatase isozyme (TNSALP). Defective/inactive TNSALP causes an increased concentration of inorganic pyrophosphate (PPi) in bone matrix that impairs bone mineralization. The accumulation of extracellular PPi observed in HPP causes impairment in bone mineralization process and leads to a disturbance of calcium and Pi homeostasis. The pathogenesis of bone hypomineralization in HPP is relatively...

 Open Access DOI:10.23937/2469-570X/1410019

Mesenchymal Stromal Cells in Cardiovascular Disease

May Al-Nbaheen

Article Type: Review Article | First Published: January 13, 2016

Mesenchymal stem cells (MSCs) can be isolated from different adult tissues and can be differentiated along stromal lineages (i.e. osteoblasts, adipocytes, and chondrocytes). Recent data in the literature provided evidence that MSCs can also be differentiated in vitro into additional cell types, such as endothelial cells. In our studies we showed the endothelial differentiation and angiogenic potential of human neonatal foreskin derived stromal cells (hNSSCs) both in vitro and in vivo....

 Open Access DOI:10.23937/2378-3656/1410086

Chronic Stimulant Use: An Upcoming Cause of Neurocognitive Disorder in Later Life?

Anne Jacobs, Sonja C. Stalpers-Konijnenburg, Cornelis A. de Jong and Radboud M. Marijnissen

Article Type: Case Report | First Published: January 26, 2016

A 58-year-old woman was admitted to a psychiatric ward because of a psychotic episode. Psychiatric history revealed chronic daily stimulant use for more than thirty years, specifically cocaine, amphetamine and nicotine. She also suffered from a psychotic episode at the age of 23 after the death of a child. Medical history did not report any somatic comorbidities....

 Open Access DOI:10.23937/2378-3656/1410085

Unusual Early Aortic Valve Bioprosthesis Failure due to Fungal Infection

Yolanda Carrascal, Gregorio Laguna and Nuria Arce

Article Type: Case Report | First Published: January 23, 2016

We report an early failure of a 19 mm mitroflow A12 aortic pericardial bioprosthetic valve. We excluded all described causes related with early bioprosthesis calcification and degeneration. Neither inflammatory cells nor bacterial colonization were identified in microscopic analysis, but fungal hyphae were observed in the tissue sections from both leaflets, suggesting sub-clinical fungal endocarditis, which might have contributed to early failure....

 Open Access DOI:10.23937/2378-3656/1410084

Therapeutic Efficacy of Platelet-Rich Plasma Injections in Treating Chronic High Hamstring Tendinopathy

Jeffrey Krauss, Ryan Nugent, Marko Bodor and Michael Fredericson

Article Type: Original Research Article | First Published: January 23, 2016

Objective: To determine whether ultrasound-guided platelet-rich plasma (PRP) injections reduce pain and improve function in patients with chronic high hamstring tendinopathy. Design: Prospective case-control study in which patients who have failed treatment serve as their own controls. Setting: Patients were recruited through two sports medicine clinics, one academically based and the other in a community medical center. Injections were performed by a single practitioner. Patients: 14 adult pati...

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ClinMed Journals Index Copernicus Values

Clinical Medical Reviews and Case Reports: 91.40

International Archives of Nursing and Health Care: 90.87

International Journal of Sports and Exercise Medicine: 91.84

Obstetrics and Gynaecology Cases - Reviews: 88.42

International Journal of Womens Health and Wellness: 91.79

Journal of Musculoskeletal Disorders and Treatment: 91.73

Journal of Geriatric Medicine and Gerontology: 91.55

Journal of Infectious Diseases and Epidemiology: 91.55

International Journal of Clinical Cardiology: 89.24

Journal of Dermatology Research and Therapy: 89.34



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VOLUME 9, ISSUE 4

International Journal of Clinical Cardiology

ISSN: 2378-2951 | ICV: 89.24

VOLUME 9 | ISSUE 4 | 2022

VOLUME 9, ISSUE 2

Obstetrics and Gynaecology Cases - Reviews

ISSN: 2377-9004 | ICV: 88.42

VOLUME 9 | ISSUE 2 | 2022

VOLUME 8, ISSUE 1

Journal of Hypertension and Management

ISSN: 2474-3690 | ICV: 87.69

VOLUME 8 | ISSUE 1 | 2022

VOLUME 9, ISSUE 2

International Journal of Diabetes and Clinical Research

ISSN: 2377-3634 | ICV: 87.97

VOLUME 9 | ISSUE 2 | 2022

VOLUME 8, ISSUE 8

Journal of Infectious Diseases and Epidemiology

ISSN: 2474-3658 | ICV: 91.55

VOLUME 8 | ISSUE 8 | 2022

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Featured Articles

Rapid Progression of Sternocostoclavicular Hyperostosis (SCCH) Observed after Anti-TNF-a Therapy for Polyarthritis: A Case Report

Atsushi Kitagawa, Mitsuhiko Takahashi, Tomoko Nakamura and Yasushi Hashimoto

DOI: 10.23937/2378-3656/1410402



Body Composition Changes in College Athletes During Holiday Breaks

Aston Dommel and R Drew Sayer

DOI: 10.23937/2469-5718/1510231



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SARS Cov-2 Infection-Related Persistent Air Leaks Managed By Endobronchial Valves

Mukund Tiwari, MBBS, Nikita Tangella, MD, Archana Sreekantan Nair, MD and Killol K Patel, MD

DOI: 10.23937/2378-3516/1410180



Right Ventricular Dysfunction in COVID-19 Patients and its Impact on Mortality

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DOI: 10.23937/2643-3966/1710051


Featured Journals

Clinical Medical Reviews and Case Reports Editor-in-chief: Prof. Wei Wang

International Journal of Surgery Research and Practice Editor-in-chief: Prof. Brian Richard Davis

International Journal of Stem Cell Research & Therapy Editor-in-chief: Prof. Faris Farassati

International Journal of Clinical Cardiology Editor-in-chief: Prof. Breijo-Marquez

Journal of Genetics and Genome Research Editor-in-chief: Prof. Ming Zhan

Obstetrics and Gynaecology Cases - Reviews Editor-in-chief: Prof. Leslie Iffy

International Journal of Cancer and Clinical Research Editor-in-chief: Prof. Sulma I Mohammed

International Journal of Diabetes and Clinical Research Editor-in-chief: Prof. Masayoshi Yamaguchi

International Journal of Anesthetics and Anesthesiology Editor-in-chief: Prof. Ike Eriator

International Journal of Respiratory and Pulmonary Medicine Editor-in-chief: Prof. Shufeng Zhou

International Journal of Sports and Exercise Medicine Editor-in-chief: Prof. J David Prologo

Journal of Rheumatic Diseases and Treatment Editor-in-chief: Prof. Bruce M Rothschild

International Archives of Urology and Complications Editor-in-chief: Prof. Ajay Singla

International Journal of Psychology and Psychoanalysis Editor-in-chief: Prof. Joaquim JF Soares

Journal of Obesity and Weight-loss Medication Editor-in-chief: Prof. Timothy Koch

Trauma Cases and Reviews Editor-in-chief: Prof. William Min

Clinical Medical Image Library Editor-in-chief: Prof.

International Journal of Transplantation Research and Medicine Editor-in-chief: Prof. Lydia M Petrovic

Journal of Otolaryngology and Rhinology Editor-in-chief: Prof. John E. Nathan

Journal of Geriatric Medicine and Gerontology Editor-in-chief: Prof. Ryuichi Morishita

International Journal of Critical Care and Emergency Medicine Editor-in-chief: Prof. Yasushi Shibata

International Journal of Womens Health and Wellness Editor-in-chief: Prof. Erich Cosmi

International Journal of Brain Disorders and Treatment Editor-in-chief: Prof. Terry Lichtor

International Journal of Clinical Biostatistics and Biometrics Editor-in-chief: Prof. James Michael Hardin