Emergency Embolization of a Rupture of the Left Colic Aneurysm
Domenico Lagana, Maria Petulla, Ierardi Anna, Gianpaolo Carrafiello and Oscar Tamburrini
Article Type: Case Report | First Published: November 25, 2015
This is a case report of an emergency embolization of a left colic aneurysm performed on a 72 year-old woman. The abdominal CTA scan showed a large retroperitoneal hematoma and an aneurysm of a branch of the inferior mesenteric artery. A selective angiography of the inferior mesenteric artery confirmed an aneurysm of the left colic artery. An endovascular ligation was performed with platinum microcoils. The 3-month follow-up confirmed the complete exclusion of the aneurysmatic vessel....
Total Pancreatectomy and Islet Auto-Transplantation for Chronic Painful Pancreatitis: An Overview
Megan Berger, Gregory J Beilman, Ty Dunn, David Sutherland and Srinath Chinnakotla
Article Type: Review Article | First Published: December 02, 2015
Chronic pancreatitis is a progressive and irreversible process that can lead to pain, pancreatic dysfunction, and even malignancy. Management can be difficult, with some patients proving refractory to standard medical or endoscopic treatments. These patients generally depend on narcotics to manage their symptoms. Total pancreatectomy and Islet Auto-Transplantation (TP-IAT) can offer relief for such patients by removing the root cause of their pain. The pancreas is entirely resected and islets ar...
Medical Student Health Literacy Perspectives and Experiences
Julienne K Kirk, Stephen W Davis, Jade Hairston, Kathryn Melius and Gail S Marion
Article Type: Research Article | First Published: November 09, 2015
Medical students described a variety of scenarios they experienced in their first two or three years of medical school and 17 quotes from the narratives were selected from 130 stories. There were four dominant themes identified from student narratives that were related to communication. These categories included information management, active listening, addressing feelings and reaching common ground. Results suggest that medical students can identify effective and ineffective communication and h...
Rethinking HIV Risks among Women on the US/Mexico Border: Alcohol and Latina Sex Behavior
Michael Parsa, Robert Woolard, Dustin Corgan, Susana Villalobos, Paul Chisolm, Lisa Montgomery, Jiayang Liu, Israel Alba and Patrick Tarwater
Article Type: Research Article | First Published: October 31, 2015
Most young Latina ED patients were unconcerned about risk of HIV infection in spite of their reports of HIV sex risk behavior. Latinas who were RAPS4 positive were more likely to report HIV sex risk behavior, but they had no greater concern about their HIV risk and no greater use of condoms. Preventive interventions should be developed to decrease alcohol use and to increase concern about HIV risk among Latinas....
Glycemic Disturbances on Admission as a Predictor of Inpatient Mortality
Daniel Saenz-Abad, Jose Antonio Gimeno-Orna, Maria del Carmen Lahoza-Perez, Elena Rivero-Sanz, Marta Jordan-Domingo, Artur Juan-Arribas, Maria del Mar Becerra-Mayor and Cristina Baquer-Sahun
Article Type: Original Research | First Published: October 30, 2015
This is a case-control retrospective analytical study. The cases were patients deceased during hospitalization and controls where those discharged in the same time period. Patients were age-matched and the final outcome of the study was hospital mortality. Rapid Emergency Medicine Score (REMS) and Charlson comorbidity index as well as blood analysis (full blood count, glucose, renal function, ions) were determined. Abnormal glucose levels (dysglycemia) were those considered to be < 70 or > 200 m...
Ventricular Arrhythmias in Acute Coronary Syndrome Patients: Therapy of Electrical Storm
Tobias Willich and Andreas Goette
Article Type: Review Article | First Published: October 01, 2015
This review provides an overview of the available therapeutic options for acute care and management of malignant ventricular arrhythmias (VA) such as ventricular tachycardia (VT), ventricular fibrillation (VF) and electrical storm (ES). As therapeutic options antiarrhythmic drug (AAD) therapy, implantable cardioverter defibrillator therapy (ICD), radiofrequency catheter ablation (RFA) and neuroaxial modulation like stellate ganglion blockade or renal denervation are available. AAD therapy is lim...
To Give or Not To Give - Is that the Question?: The Changing Face of Emergency Oxygen Therapy
Carol Ann Kelly and Dave Lynes
Article Type: Non-systematic Review | First Published: September 14, 2015
Oxygen's image, together with its reputation, is changing. No longer is it regarded as a benign panacea for all clinical presentations; indeed it is now increasingly evident that oxygen has the potential to contribute to clinical deterioration and mortality. There is an emerging recognition that oxygen is a drug when administered as a therapeutic intervention and should be used with caution. Contemporary guidelines offer criteria and directives for administration and prescription of oxygen, depe...
A Constrained Non-inferiority Approach for Assessing Clinical Efficacy to Establish Biosimilarity
Jason JZ Liao
Article Type: Research Article | First Published: December 3, 2015
To develop a biosimilar product, it is necessary to demonstrate biosimilarity between the proposed biosimilar product and the reference product in terms of the purity, potency, efficacy, and safety. In this paper, clinical efficacy data required for establishing biosimilarity are considered. Non-inferiority (NI) and equivalence methods are commonly used for analyzing clinical trials to meet this requirement. The equivalence approach often requires large, costly, and lengthy clinical trials....
Cross-Sectional Exploration on Feeding Practices of Feeders towards Preschoolers' Picky Eating Behaviors
Louisa Ming Yan Chung and Shirley Siu Ming Fong
Article Type: Original Article | First Published: November 14, 2015
Picky eating is quite common among preschoolers, which may lead to imbalanced diet. Picky eating behavior among preschoolers was found associated with feeding style. With the complex family structure of 2-career parents in Hong Kong and unique authoritarian Chinese feeding style, this study aimed to explore the differences in feeding practices among different preschoolers' feeding persons and to investigate if preschoolers' picky eating showed differences if they are fed by different feeding per...
Effect of Race/Ethnicity and Smoking on Diurnal Variations in Testosterone Levels
Ram B Jain
Article Type: Research article | First Published: December 10, 2015
The effect of race/ethnicity and smoking on diurnal variations in total serum testosterone level (T-TST) was evaluated by analyzing data from NHANES for 2011-2012 for adolescent and adult males. For adolescent males, diurnal variability in T-TST levels was substantially smaller among smokers than nonsmokers for non-Hispanic white (NHW) and Hispanics but the reverse was true for non-Hispanic black (NHB). For adult males, morning levels of T-TST were 21-31% higher than the T-TST levels during even...