ClinMed International Library

The ClinMed International Library is a repository and an open access publisher for medical research that covers a wide range of areas in Clinical Medicine. ClinMed serves as a global platform for medical practitioners and research scholars to foster their learning and professional acumen through an extensive portfolio of research articles and publications that can be accessed without any restrictions.

Dedicated to clinical medical research, we now publish over 70 quality peer-reviewed journals making all the articles freely accessible. The manuscripts submitted to ClinMed will be processed through standard parameters and international peer review systems. This has enabled us to establish new milestones in the global research arena in terms of cogency and integrity, and to disseminate highly credible and accredited research content for researchers, scholars, and practitioners across the globe.

We ensure that all researchers and authors publishing their papers with us retain copyrights, licensed under Creative Commons Attribution License that permits the unrestricted use and re-use of the content with proper citation.

ClinMed International Library


Articles Published

All articles are fully peer reviewed, free to access and can be downloaded from our ClinMed archive.

Articles Search by   Keyword   |   Journal title   |   Author name   |   DOI

 Open Access DOI:10.23937/2469-5734/1510097

Prevalence of Dental Amalgame in Uninassau School of Dentistry Clinic

Ana Kaline da Silva Pereira and Lívia Andrade Rodrigues

Article Type: Research Article | First Published: September 02, 2019

The dental amalgam is any alloy consisting of mercury, in which we can also find silver (Ag), tin (Sn) and copper (Cu) in its conventional filings. This type of restorative material is the focus of discussion in several countries, raising a great discussion about the continuity or elimination of its use, the reasons are: For the sake of offering little aesthetics or for providing possible risks for the dentist and the patient, due to the presence of mercury in its composition, since it is a volatile and toxic metal. Amalgam still in a certain way has a great importance in the present day, in a...

 Open Access DOI:10.23937/2469-5734/1510096

Use of Platelet-Rich Plasma in Autogenous Bone Graft in Implantology

Gleycielly da Mota Oliveira Souza, Carolina de Lima Borges, Rosa Natalia Rendall dos Santos Ratis and Vivian Kelly Leite Pedrosa

Article Type: Review Article | First Published: September 02, 2019

The use of platelet-rich plasma (PRP) in implantology has potentiated bone regeneration and the healing process, reducing postoperative period, inflammatory process and blood loss. The objective of this study is to verify, based on the literature, the use of PRP in bone regeneration in autogenous grafts, to show its indications and benefits in bone formation and techniques used. A literature review was performed on the efficacy of PRP in autogenous bone grafts in implantology. The databases used were PubMed, Scielo and BVS. In this study, 30 articles from the years 1983 to 2017 were selected d...

 Open Access DOI:10.23937/2469-5734/1510095

Methotrexate Effects at High Doses in the Progression of Inflammatory Periapical Lesions in a Murine Model: Histological and Imaginological Analysis

Silvana Freitas de Souza Leao and Danyel Elias da Cruz Perez

Article Type: Research Article | First Published: August 26, 2019

Treatment for cancer patients can cause significant side effects in the maxillofacial region. The type and intensity of side effects will depend on the mechanism of action of the drugs used. Among these drugs, there are those that cause predominantly cytotoxic acute effects, such as methotrexate. Methotrexate (MTX), 4-amino-N10-methyl pteroylglutamic acid, a synthetic drug also known as amethopterin, is an antimetabolite that is structurally similar to folic acid. MTX interferes with the synthesis and repair of DNA during cell replication and has anti-inflammatory and antineoplastic properties...

 Open Access DOI:10.23937/2378-346X/1410109

Repeat Visual Field Assessments for Patients with Normal Visual Field Tests at their Referring Optometric Practice

A Alwitry and S Hubbard

Article Type: Original Research | First Published: September 07, 2019

To determine whether a normal visual field assessment at a referring optometric practice is predictive of a normal visual field assessment at the hospital eye service and therefore whether there is any need to repeat it prior to first hospital visit. Data on visual fields of 501 consecutive patients, 1002 eyes/visual field assessments were collected. The positive predictive value of a normal visual field at the patients referring optometrist was 97% for the right eye and 98% for the left eye. From all the visual field assessments the rate of a visual field where the glaucoma hemifield test (GH...

 Open Access DOI:10.23937/2378-3664.1410030

The Case for Viscoelastic Treatment of Excessive Girth in Treatment of the Presentation of a Spastic Colon: A Role for a Girth Injury Index?

Gareth R Williams, Timothy J Prior, Geoffrey Hayes, Barry L Chuckle, and Chas N Dave

Article Type: Short Communication | First Published: August 26, 2019

Spastic colon injure tangible introduces viscoelastic jumpy moist introduces value overconfident tangible value introduces tame; tame tangible overconfident efficacy tame tangible curtail overconfident tangible overconfident injure girth moist island spastic colon. Viscoelastic tangible island and therefore spastic colon injure viscoelastic and therefore tame spastic colon moist curtail efficacy island girth introduces spastic colon jumpy in tangible and therefore moist girth viscoelastic tame overconfident and therefore spastic colon island injure in tangible value jumpy curtail jumpy tame va...

 Open Access DOI:10.23937/2378-3664.1410029

A Supramolecular Indicator System for Detecting Urea Based on the Cellulose-Nanodiamond Composite Material and Urease

Ekaterina Posokhina, Nikita Ronzhin, Olga Mogilnaya, Alexey Baron and Vladimir Bondar

Article Type: Research Article | First Published: August 14, 2019

A supramolecular indicator system (cellulose-nanodiamonds- urease) for reusable biochemical detection of urea has been fabricated using sequential immobilization of the components. Modified nanodiamonds (MNDs) were covalently immobilized onto DEAE cellulose granules via the nucleophilic addition reaction. At DEAE cellulose: MND ratio of 4:1 (w/w), up to 110 μg of nanoparticles bound onto 1 mg of the polymer during the addition reaction. Urease was immobilized by covalent conjugation onto the polymer-MND composite with the benzoquinone-activated surface. In comparative experiments, the enzyme ...

 Open Access DOI:10.23937/2378-3672/1410038

The Role of Genetics Mutations in Genes PORCN, TWIST2, HCCS in Goltz Syndrome

Shahin Asadi and Mahsa Jamali

Article Type: Review Article | First Published: August 26, 2019

Goltz syndrome (focal skin hypoplasia) is a genetic disorder that primarily affects the skin, skeletal system, eyes and face. People with Goltz syndrome have birth defects. These disorders include very thin skin veins (skin hypoplasia), pink yellow nodules, subcutaneous fat, lack of upper skin layers (aplasia cutis), small clusters of superficial skin vessels (telangiectasia), and veins in dark skin Or bright. Goltz syndrome is caused by mutation genes PORCN, TWIST2, HCCS. Goltz syndrome (focal skin hypoplasia) is a genetic disorder that primarily affects the skin, skeletal system, eyes and fa...

 Open Access DOI:10.23937/2378-3672/1410037

Rituximab Modifies Peripheral Blood Mononuclear Cells Immune Responses

Meir-Djaldetti, MD, Chyia-Leibovitch, MD, Esther-Ganelin-Cohen, MD, PhD and Hanna-Bessler, PhD

Article Type: Research Article | First Published: August 26, 2019

Rituximab, the monoclonal antibody against B lymphocyte protein CD20, is a major asset for treatment of diseases in which B CD20 cells are the foremost etiologic culprit. Based on observations that rituximab is capable to modulate immune responses the question if the drug may affect the capacity of human peripheral blood mononuclear cells (PBMC) for cytokine production was posed. The discovery of rituximab, a monoclonal antibody against B lymphocyte membrane protein CD20, contributed greatly to the treatment of B-cell non-Hodgkin’s lymphoma and certain autoimmune diseases such as rheumatoid ...

 Open Access DOI:10.23937/2643-3885/1710032

Plantar Fasciitis Rupture - Who is the Culprit?

Fairuz Suhaimi

Article Type: Case Report | First Published: August 26, 2019

The plantar fascia is an important structure in the foot, which helps, stabilizes the arch of the foot during motion and provides shock absorption when the foot hits the ground. Inflammation of the plantar fascia has been high in incidence, with multiple factors attributed to it. However, occurrence of the plantar fascia rupturing is not common. Corticosteroid injection to the plantar fascia has long been advocated as the major cause of this. Nonetheless, in recent literatures, corticosteroid injections have been shown to be safe and provide good results in treating pathologies of the plantar ...

 Open Access DOI:10.23937/2643-3885/1710031

Freiberg's Infraction in a Geriatric Patient - A Case Report

Daniel Pollack, DPM, FACFAS

Article Type: Case Report | First Published: August 17, 2019

Foot pain is debilitating and common, especially in the geriatric population. It causes difficulty, or an inability, to ambulate which may lead to further issues such as weight gain, reliance on others for assistance, and imbalance which can lead to falls. It is important to consider Freiberg's infraction as a cause of foot pain in the elderly, even if it normally occurs in younger patients. Freiberg's infraction (also known as Freiberg's disease) is premature bone death, or osteonecrosis, of most commonly the head of the second metatarsal bone in the foot, occurring most commonly the in secon...

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Role of Oxidative Stress and Apoptosis in the Hepatic Toxicity Induced by Cerium Oxide Nanoparticles Following Intratracheal Instillation in Male Sprague-Dawley Rats

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