Host-Related Predictors of Persistence of Hepatitis C Virus Infection
Engy Mohamed El-Ghitany and Azza Galal Farghaly
Article Type: Research Article | First Published: November 16, 2019
Spontaneous clearance occurs in varying proportions in individuals infected by hepatitis C virus (HCV). However, the factors associated with this clearance are debatable. Their recognition may lead to a better understanding of HCV natural history and eventually improve associated prediction and management models. Aim: This study was conducted to determine the host-related factors associated with persistence of HCV infection. Among 1059 HCV-antibody-positive individuals who denied receiving HCV antiviral treatment, 257 (24.3%) spontaneously cleared the virus. Patient groups with persistent infe...
Statistical Behavior of Hospital Admissions for Respiratory Diseases by Probability Distribution Functions
Amaury de Souza, Flavio Aristone, Widinei A Fernandes, Zaccheus Olaofe, Marcel Carvalho Abreu, Jose Francisco de Oliveira Junio, Guilherme Cavazzana and Cícero Manoel dos Santos
Article Type: Research Article | First Published: November 04, 2019
Climate change has a high impact on health and morbidity/ mortality in respiratory system diseases and remains poorly investigated in probability distribution modeling. The objective of this study was to analyze the adjustments of Burr (Bu), Inv Gausian 3P (IG3P), Lognormal (LN), Pert (Pe), Rayleigh 2P (Ra 2P) and Weibull 3P (W3P) distributions of the historical series of hospitalizations for respiratory diseases (total hospital admissions) for the period from 2004 to 2018, in Campo Grande, MS. For the data series, the shape and scale parameters of the distributions were determined to verify t...
Cytogenetics of Chrysichthys nigrodigitatus as Bioindicator of Environmental Pollution from Two Polluted Lagoons, South- Western Nigeria
Bassey OB, Chukwu LO and Alimba GC
Article Type: Research Article | First Published: November 14, 2019
Pollution of aquatic ecosystems from anthropogenic activities has heightened in recent times and this has elicited national and international concern on the impacts on aquatic biota. This study investigated the genotoxic effects in C. nigrodigitatus from two polluted lagoons. Micronuclei (MN) test, as an index of chromosomal damage, is widely applied in field studies. The peripheral erythrocytes from C. nigrodigitatus were subjected to MN analysis and physicochemical parameters were evaluated following APHA standardized protocol. There were significant (p < 0.05) seasonal variations in water t...
Risk Factors for Mucosal Ulceration in Gastric Gastrointestinal Stromal Tumors (GIST)
Eran Ariam, Anton Bermont, Yehuda Herskovitz, Shay Matalon, Bard Vyacheslav, Reut Yaakobi, Daana Baseem, Fadi Younis, Asia Zubkov, Efrat Broide, Benjamin Avidan, Steven F Moss and Haim Shirin
Article Type: Case Report | First Published: November 18, 2019
Gastrointestinal stromal tumors (GIST) are the most common subepithelial tumors in the gastrointestinal (GI) tract and they are usually located in the stomach. To date, only a few studies have investigated the risk factors for GIST ulceration and bleeding and there have been no prior publications focused on role of Helicobacter pylori in GIST ulceration. The aim of current study was to investigate the risk factors of mucosal ulceration in gastric GISTs. A retrospective study was conducted of 130 patients with a histological diagnosis of gastric GIST, recruited from four medical centers in Isra...
Assessment of Reproductive and Sexual Health Literacy of Women in Armenia
Mariam Barseghyan, MD, MS, Hayk Barseghyan, PhD, Gardenia E Nahigian, BA, Eric J Vilain, MD, PhD, Elena Sagayan, MD and Michael S Wilkes, MD, MPH, PhD
Article Type: Research Article | First Published: November 07, 2019
Study consisted of 173 female participants (medical personnel and general respondents) from villages of Armavir and Lori Marz in the Northern Armenia who completed confidential self-filled and validated surveys in Armenian. Questions covered demographics and addressed risk factors, symptoms, and modes of prevention of STIs and cervical cancer as well as contraceptive choices of women. Respondents’ answers were tabulated, and common themes identified. Comparison was made between general population and health care workers level of knowledge on specific topic. Both general population and medica...
Lady or Gentleman? Sex Differences in Osseous and Cartilaginous Structures of the Knee
Lauren C Pringle, MD, Miho J Tanaka, MD and Laura M Fayad, MD
Article Type: Research Article | First Published: November 11, 2019
We performed a comprehensive review of imaging investigations of knee morphology comparing male and female subjects using PUBMED, with search terms for CT/MRI, knee anatomy, and gender. Inclusion criteria were primary imaging investigations of knee osseous/cartilage anatomy (minimum 15 subjects); exclusion criteria were studies of post-operative patients, those with comorbid orthopedic conditions, and review articles. Sex differences in osseous/cartilage anatomy were extracted and aggregated. Of 1550 citations reviewed, 84 studies met inclusion criteria and fell into 5 categories: Bony axes o...
Complex High Turnover in Bone Metabolism Impairs Bone Quality in Female Long-Distance Runners with Menstrual Disorders
Eiji Sasaki, Yuki Fujita, Katsuro Yoneda, Shoko Kinugasa, Ken Kato, Eiichi Tsuda, Yasuyuki Ishibashi and Takashi Umeda
Article Type: Research Article | First Published: November 09, 2019
Menstrual disorder is a risk factor for stress fracture. Stress fractures impede running activity in female long-distance runners. However, the bone metabolism of female long-distance runners, and its relationship with bone quality, are not understood. We examined the characteristics of bone metabolism and bone quality in female long-distance runners with menstrual disorder. Sixteen female university long-distance runners and 31 young female non-athlete volunteers were enrolled. Self-reported menstrual condition was recorded. Serum estradiol, collagen type 1 cross-linked N-telopeptide (NTx), p...
Comparison of Active and Sedentary Bout Lengths in Normal and Overweight Adults using eMouverecherche
Ludivine Paris, Romain Guidoux, Damien Saboul, Martine Duclos, Yves Boirie and Sylvie Rousset
Article Type: Research Article | First Published: November 04, 2019
Physical inactivity and long sedentary time are common in obese people. The eMouveRecherche application was developed to provide accurate minute-by-minute classification of physical activity in light, moderate, vigorous intensity and sedentary bouts. The aim was to compare the frequency and length of bouts in Normal-Weight (NW) and Overweight (OW) adults. Fifty-seven adult participants either normal weight or overweight wore a smartphone with the eMouve application for the entire waking period of the day. The continuous 1-5, 5-15, 15-30, 30-60 and higher than 60-minute bouts for each behavior ...
Research of Prognostic Role of MSI in Endometrioid Adenocarcinoma Cases That Received Postoperative Radiotherapy
Kadriye Sahinturk, MD, Candan Demiroz Abakay, MD, Serdar Sahinturk, MD, PhD, Sebnem Ozemri Sag, Fatma Atalay, Fatma E Can, Meral Kurt, MD, and Sibel Kahraman Cetintas, MD
Article Type: Original Article | First Published: November 11, 2019
One hundred twenty four endometrium cancer patients who were referred for postoperative external radiotherapy and/or brachytherapy during the period between January 2002 and December 2012 at Uludag University Radiation Oncology Department. Out of three all patients received radiotherapy. Since 11 had mixed type pathology, 9 had unspecified paraffine blocks and 2 had unsuccessful MSI analysis, study was performed with 99 patients and all re-staged according to FIGO 2009 staging system. Tumor tissue specimens were extracted within formalin fixed, paraffin-embedded sample tissue. Tumor tissue DNA...
Contribution of 99M TC-HMDP Bone Scintigraphy in the Diagnosis of Fibrous Dysplasia of Mccune Albright Syndrome in Infant: A Case Report
F Fokoue, S El Mselmi and N Ismaili Alaoui
Article Type: Review Article | First Published: November 16, 2019
McCune Albright syndrome is a rare congenital disorder, which is classically defined by a triad associating a Fibrotic Dysplasia (DF) most often polyostotic, "cafe au lait" skin pigmentation and a hyperfunctioning endocrinopathy. "Cafe au lait" skin pigmentations are macules which are common and mostly the first manifestation of the disease, apparent at or shortly after birth. Fibrous Dysplasia (FD), which can involve any part and combination of the craniofacial, axial, and/or appendicular skeleton, can range from an isolated, asymptomatic monostotic lesion discovered incidentally to severe di...