ClinMed International Library

For the past decade, ClinMed International Library has been at the forefront of publishing cutting-edge research in clinical medicine. Over the last 10 years, we have consistently provided a platform for publishing innovative findings and advancements in medical science.

The ClinMed International Library is a repository and an open access publisher for medical research that covers a wide range of areas in Clinical Medicine. ClinMed serves as a global platform for medical practitioners and research scholars to foster their learning and professional acumen through an extensive portfolio of research articles and publications that can be accessed without any restrictions.

Dedicated to clinical medical research, we now publish over 70 quality peer-reviewed journals making all the articles freely accessible. The manuscripts submitted to ClinMed will be processed through standard parameters and international peer review systems. This has enabled us to establish new milestones in the global research arena in terms of cogency and integrity, and to disseminate highly credible and accredited research content for researchers, scholars, and practitioners across the globe.

We ensure that all researchers and authors publishing their papers with us retain copyrights, licensed under Creative Commons Attribution License that permits the unrestricted use and re-use of the content with proper citation.



  Last Updated: December 11, 2024

Articles Search by   Keyword   |   Journal title   |   Author name   |   DOI

 Open Access DOI:10.23937/2378-3397/1410037

A Rare Case of Biliary Atresia and Choledochal Cyst in a Premature Infant

Abigail B Podany, Ryan M Juza, Sosamma T Methratta, Peter W Dillon, Mary C Santos, Brett W Engbrecht, Robert E Cilley, Dorothy V Rocourt and Karmaine A Millington

Article Type: Case Report | First Published: February 28, 2016

Recent case reports have described variants in the classification of biliary atresia and choledochal cyst requiring the expansion of the classical system for describing these anomalies. This in effect, further obscures the line between these two previously separate entities while highlighting the difficulties of intraoperative differentiation of biliary atresia, cystic biliary atresia, choledochal cyst, and Caroli's disease. In our case report, we describe a 34-week premature infant who develope...

 Open Access DOI:10.23937/2378-3397/1410036

Transcatheter Embolization of a Large Coronary Artery Fistula in a Child

Gorbatykh A, Krestjaninov O, Soynov I, Voitov A and Nichay N

Article Type: Case Report | First Published: January 25, 2016

Coronary artery fistula is a rare congenital disease of a coronary circulation. The progress is usually favorable, but in case of a large right atrial coronary fistula a volume overload with a progressing heart failure may occur. Conventional treatment involves fistula's closure using cardiopulmonary bypass. We present a case of endovascular closure of a large coronary artery-to-right atrium fistula....

 Open Access DOI:10.23937/2469-5807/1510029

Micronutrients Deficiencies in Rheumatoid Arthritis Patients

Graziela Biude Silva, Bruna Zavarize Reis and Silvia Maria Franciscato Cozzolino

Article Type: Mini Review | First Published: February 29, 2016

Rheumatoid arthritis (RA) is a chronic inflammatory disease that predominantly involves synovial joints and affects up to 2% of adults worldwide. Poor nutrient status in RA patients has been reported and some drug therapies, such as nonsteroidal anti-inflammatory drugs (NSAIDs), prescribed to alleviate RA symptoms, may increase the requirement for some nutrients and reduce their absorption. The importance of micronutrients in this disease is related to their cofactor role in immune system functi...

 Open Access DOI:10.23937/2469-5807/1510028

Research Progress of STK33 in Cancer Biology

Chen Chen and Jianfeng Li

Article Type: Mini Review | First Published: February 29, 2016

In recent years, serine/threonine kinase 33 (STK33) has attracted considerable attention in tumor biology. STK33 displays a heterogenous expression pattern, and in most tissues, expression level is low. It belongs to the CAMK family, and differentiates itself from other members of the CAMK family due to its expression pattern. STK33 is likely to participate in the dynamic changes of intermediate filament cytoskeleton depolymerization by phosphorylating vimentin, and thereby influencing the cell ...

 Open Access DOI:10.23937/2469-5807/1510027

JAK2V617F Mutation Affects Downstream LIN28A and HMGA2 Methylation in Myeloproliferative Neoplasms

Chih-Cheng Chen, Chia-Chen Hsu, Kuan-Der Lee, Chia-Chen Chiu, Hong-Chi Chen, Tim H.-M. Huang, Yu-Wei Leu and Shu-Huei Hsiao

Article Type: Mini Review | First Published: February 29, 2016

The lineage/clonal selection theory for cellular transformation may help identify the effector genes whose functions are crucial for MPN tumorigenesis. MPNs originate from hematopoietic stem cells carrying compartmental mutations such as JAK2V617F. JAK2 signaling regulates target gene expression by altering the phosphorylation and nuclear localization of STATs. To provide selectable gene expression that promotes transformation of certain cellular lineages, specific signals relayed to the cell nu...

 Open Access DOI:10.23937/2469-570X/1410024

Function of Sirtuins in Cancer Stem Cells

Zhen Dong and Hongjuan Cui

Article Type: Review Article | First Published: February 08, 2016

Cancer stem cells (CSCs) are self-renewing cancer cells in tumors that are suggested to be responsible for tumor initiation, progression and relapse. The molecular mechanisms of CSCs biology could provide some novel managements for cancer treatment. Sirtuins, as a family of class III deacetylases, are recently found to play essential roles in the maintenance and differentiation of various cancer stem cells, including glioma stem cells (GSCs), colorectal cancer stem cells (CCSCs), breast cancer s...

 Open Access DOI:10.23937/2469-570X/1410023

Cell-based Therapy for Treatment of Diabetes Mellitus: Can the Agonists of Growth Hormone-releasing Hormone Make a Contribution?

Xianyang Zhang, Norman L. Block and Andrew V Schally

Article Type: Review Article | First Published: February 04, 2016

Beta cell replacement, to supply the body with cells producing insulin, is considered as one of the most important alternative approaches to the treatment of diabetes. Transplantation of human islets and the resulting progressive improvement of clinical results confirm the approach as a positive trend in this field. Recent progress in beta cell differentiation, deriving from many types of pluripotent stem cells, has potentially provided an unlimited source of β cells for research and clinic...

 Open Access DOI:10.23937/2469-570X/1410022

Stem Cell Approach to Generate Cancer Specific Immune Effectors Cells

Sylvie Shen, Ning Xu, Geoff Symonds and Alla Dolnikov

Article Type: Review Article | First Published: February 04, 2016

The ability to target cancer cells using genetically enhanced immune effector cells armed with a chimeric antigen receptor (CAR) capable of recognising tumour associated antigen is a novel approach to the treatment of cancer. Remarkable success in early phase clinical trials has demonstrated a potent anti-cancer effect of T cells modified to express CAR (CART cells) targeting CD19+ B-cell malignancies....

 Open Access DOI:10.23937/2378-3648/1410021

A Comparison of SNaPshot Minisequencing and HRM Analysis in mtSNP Genotyping with Reference Samples from East Timor

Luis Souto, Filipa Tavares, Helena Moreira and Fatima Pinheiro

Article Type: Research Article | First Published: December 28, 2015

The analysis of mtDNA in forensic samples is commonly carried out by direct sequencing of the hyper variable regions of the control region, although with limited power of discrimination. Genotyping SNPs in the coding region of mtDNA can provide additional information and increase the discrimination power of mtDNA typing. In this study, we compare two methodologies for the detection of 9 SNPs in the control region of mtDNA: SNaPshot minisequencing and Real Time PCR, through High-Resolution Meltin...

 Open Access DOI:10.23937/2572-4010.1510011

Physical Exercise versus Natural Estrogen Supplement in Treatment of Metabolic Syndrome in Aged Postmenopausal Wistar Rats

Bahgat NM, Saad RA, Lasheen NN and Sabry YG

Article Type: Research Article | First Published: February 26, 2016

The present study was performed to evaluate the effects of either a low intensity swim- exercise program or low soybean flour supplementation on the different components of metabolic syndrome in aged postmenopausal rats. Fifty five rats, weighing 260-350 gm, were randomly allocated into: Control group (C), Metabolic Syndrome group(MS), Metabolic syndrome 6-week - swim exercised group (MSE), and Metabolic syndrome 6 week -soybean flour supplemented group (MSS)....

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All articles are fully peer reviewed, free to access and can be downloaded from our ClinMed archive.

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All Indexed Journals

Partnered with ICI World of Journals. Check the Index Copernicus Values of ClinMed Journals

ClinMed Journals Index Copernicus Values

Clinical Medical Reviews and Case Reports: 91.40

International Archives of Nursing and Health Care: 90.87

International Journal of Sports and Exercise Medicine: 91.84

Obstetrics and Gynaecology Cases - Reviews: 88.42

International Journal of Womens Health and Wellness: 91.79

Journal of Musculoskeletal Disorders and Treatment: 91.73

Journal of Geriatric Medicine and Gerontology: 91.55

Journal of Infectious Diseases and Epidemiology: 91.55

International Journal of Clinical Cardiology: 89.24

Journal of Dermatology Research and Therapy: 89.34



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Content Registration at Crossref and DOI assignment for all published articles

Why ClinMed?

Highly Indexed Journals
Preservation of author rights
Global followership
Non-commercial objectives
Neutral and unbiased publishing process
Reprints issued accross the world
Timely submission for indexing
Published with CrossMark® policy

New Issues

VOLUME 10

International Journal of Clinical Cardiology

ISSN: 2378-2951 | ICV: 89.24

VOLUME 10

VOLUME 10

Obstetrics and Gynaecology Cases - Reviews

ISSN: 2377-9004 | ICV: 88.42

VOLUME 10

VOLUME 9

Journal of Hypertension and Management

ISSN: 2474-3690 | ICV: 87.69

VOLUME 9

VOLUME 10

International Journal of Diabetes and Clinical Research

ISSN: 2377-3634 | ICV: 87.97

VOLUME 10

VOLUME 9

Journal of Infectious Diseases and Epidemiology

ISSN: 2474-3658 | ICV: 91.55

VOLUME 9

Featured Articles

Rare Case of Uterine Rupture: 29-Week Interstitial Pregnancy

Camille Blouin, MD and Karine Girard, MD, FRCSC

DOI: 10.23937/2377-9004/1410261



Woven EndoBridge (WEB) Device used for Vertebral Artery Sacrifice

Jason J. Sims, Bhageeradh Mulpur, MD2, Nick Khattar, MD and Adam A. Arthur, MD, MPH

DOI: 10.23937/2643-4474/1710163



A Pictorial Essay on Fibromuscular Dysplasia Imaging: Beyond the String of Beads

Mohamed Nashnoush, Michael Negussie, Manasvi Gupta, Sidra Bharmal, Tresha Sivanesanathan, Yanuga Raveendran, Sherry Eskander, Gaurang Bhatt, Armaan Kotadia, Mansi Rathod, Sushmethaa Vijayakumar Shanthi, Jack Wellington, Jouhar Kolleri and Ibsen Ongidi

DOI: 10.23937/2572-3235.1510125



Acute Appendicitis Associated with Mesenteric Tuberculosis: A Case Report

Lair Antonio Lopez Velazquez, Mauricio Davila Cacique, Metztli Erreguin Brena, Ricardo Martin Lerma Alvarado and Maria del Carmen Aburto Fernandez

DOI: 10.23937/2378-3397/1410168


Featured Journals

Clinical Medical Reviews and Case Reports Editor-in-chief: Prof. Wei Wang

International Journal of Surgery Research and Practice Editor-in-chief: Prof. Brian Richard Davis

International Journal of Stem Cell Research & Therapy Editor-in-chief: Prof. Faris Farassati

International Journal of Clinical Cardiology Editor-in-chief: Prof. Breijo-Marquez

Journal of Genetics and Genome Research Editor-in-chief: Prof. Ming Zhan

Obstetrics and Gynaecology Cases - Reviews Editor-in-chief: Prof. Leslie Iffy

International Journal of Cancer and Clinical Research Editor-in-chief: Prof. Sulma I Mohammed

International Journal of Diabetes and Clinical Research Editor-in-chief: Prof. Masayoshi Yamaguchi

International Journal of Anesthetics and Anesthesiology Editor-in-chief: Prof. Ike Eriator

International Journal of Sports and Exercise Medicine Editor-in-chief: Prof. J David Prologo

Journal of Rheumatic Diseases and Treatment Editor-in-chief: Prof. Bruce M Rothschild

International Archives of Urology and Complications Editor-in-chief: Prof. Ajay Singla

International Journal of Psychology and Psychoanalysis Editor-in-chief: Prof. Joaquim JF Soares

Journal of Obesity and Weight-loss Medication Editor-in-chief: Prof. Timothy Koch

Trauma Cases and Reviews Editor-in-chief: Prof. William Min

Clinical Medical Image Library Editor-in-chief: Prof.

International Journal of Transplantation Research and Medicine Editor-in-chief: Prof. Lydia M Petrovic

Journal of Otolaryngology and Rhinology Editor-in-chief: Prof. John E. Nathan

Journal of Geriatric Medicine and Gerontology Editor-in-chief: Prof. Ryuichi Morishita

International Journal of Critical Care and Emergency Medicine Editor-in-chief: Prof. Yasushi Shibata

International Journal of Womens Health and Wellness Editor-in-chief: Prof. Erich Cosmi

International Journal of Brain Disorders and Treatment Editor-in-chief: Prof. Terry Lichtor

International Journal of Clinical Biostatistics and Biometrics Editor-in-chief: Prof. James Michael Hardin