International Journal of Tropical Diseases is an open access peer reviewed journal dealing with the infectious diseases that break out in hot, humid conditions, such as malaria, lymphatic filariasis, chagas disease, african trypanosomiasis, leishmaniasis, schistosomiasis, onchocerciasis, and dengue, etc. The journal is open in gathering high quality awareness among diseases thosefall in diverse group of communicable diseases that prevail in tropical and subtropical conditions.

Journal gathers original research, reviews, communications, letters, cases and short articles related to chagas disease, dengue, helminths, african trypanosomiasis, leishmaniasis, leprosy, lymphatic filariasis, malaria, onchocerciasis, schistosomiasis, sexually transmitted infections, TB-HIV, TB, neglected tropical diseases, "exotic" diseases, prevention and treatment of tropical diseases, controlling tropical diseases, globalization and disease, etc. The journal includes recent advances in improving the understanding of disease and the safe and effective treatment of patients. Published articles are available online without any barriers to use and reuse under the terms of attribution license.

 
Journal Information

Title: International Journal of Tropical diseases

ISSN: 2643-461X

NLM title abbreviation: Int J Trop Dis

ISO abbreviation: Int J Trop Dis

Other titles: IJTD

Category: Infectious diseases

DOI: 10.23937/2643-461X

Peer review: Double blind

Review speed: 3 weeks

Fast-track review: 10 days

Publication format (s): Electronic and print

Publication policy: Open Access; COPE guide

Publication type(s): Periodicals

Publisher: ClinMed International Library

Country of publication: USA

Language: English

Contact email: contact@clinmedjournals.org

 
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 Open Access DOI:10.23937/2643-461X/1710080

Situation Analysis of Leprosy in Jhapa District of Nepal

Dipsikha Aryal, Sudikshya Neupane, Shiekha Basnet and Prarthi Shrestha

Article Type: Viewpoint/Opinion | First Published: 2024/10/05

Mycobacterium leprae is the cause of leprosy, a chronic infectious disease that mostly affects peripheral nerves. Early diagnosis and treatment of leprosy can avoid impairment as it is a curable illness. Since December 2009, Nepal has successfully eliminated leprosy as a public health problem, with a declaration of complete elimination in 2010. Eleven local levels in Nepal's Jhapa district have a high prevalence of leprosy (more than one case per 10,000 populations) 13 years after the disease wa...
 

 Open Access DOI:10.23937/2643-461X/1710079

Nosocomial Dengue Infection in a Haematopoietic Stem Cell Transplantation Unit

Martin Castro, Maria Margarita Fernandez, Karla Oliveros, Claudia Salgueira, Antonio Carnie, Nicolas Fernandez Escobar, Guillermo Drelichman, Jose Scapellato and Gregorio Jaimovich

Article Type: Case Report | First Published: 2024/10/04

As haematopoietic stem cell transplantation (HSCT) continues to expand, infectious complications due to endemic viral and parasitic agents will became relevant. Dengue virus (DENV) infection is endemic in tropical and subtropical countries, and it is transmitted from person to person through mosquitoes. Transmission through transfusion and haematopoietic stem cells has also been described. We report a nosocomial outbreak of DENV affecting 4 transplant recipients. Patients presented fever, skin r...
 

 Open Access DOI:10.23937/2643-461X/1710078

A Neglected Tropical Disease in a Lebanese Patient: Chromoblastomycosis

Joe Khodeir, Paul Ohanian and Hala Abi Rached Megarbane

Article Type: Case Report | First Published: 2024/07/31

Histopathology showed hyperkeratotic skin with pseudoepitheliomatous epidermis and marked mixed interstitial inflammation suggestive of an infectious process. However, initial tests were inconclusive until characteristic spherical spores, indicative of muriform bodies, were identified through potassium hydroxide examination. Treatment with terbinafine was ineffective, but a multidrug regimen including cryotherapy, topical 5-Fluorouracil, and oral itraconazole resulted in significant lesion regre...
 

 Open Access DOI:10.23937/2643-461X/1710077

Neonatal Anemia: Prevalence, Associated Factors, and Impact of Malaria in a Newborn Population at the University Hospital Center of Libreville

Minko J, Mbang Nguema OA, Moutombi Ditombi B, Lembet Mikolo AM, Ovengue FC, Mawili Mboumba DP, Ategbo SJ and Bouyou-Akotet MK

Article Type: Research Article | First Published: 2024/07/07

Demographic, clinical, and paraclinical variables of the newborns, as well as maternal histories were prospectively collected in 2015. A thick drop and a complete blood count were performed....
 

 Open Access DOI:10.23937/2643-461X/1710076

Natural Plant-Based Mosquito Repellent Products: A Potential Complementary Tool for Malaria Vector Control Intervention and Elimination in Zimbabwe

David Singleton Nyasvisvo, Tamuka Nhiwatiwa, Rudo Sithole and Shadreck Sande

Article Type: Review Article | First Published: 2024/03/13

Malaria claims millions of lives globally and it is an important public health threat in Zimbabwe where more than half of the population is at risk of contracting it annually. This paper reviews published data on the evaluation of natural plant-based mosquito repellent products for malaria vector control intervention in Zimbabwe and proposes enhanced assessments of several plants with mosquito-repellent properties given the necessity of new products to prevent malaria in the country....
 

 Open Access DOI:10.23937/2643-461X/1710075

Prevalence of Gastrointestinal Parasitic Infections in Yaounde III Subdivision, Cameroon during the Covid-19 Pandemic

Djoukouo Djontu Sylvia Isabelle, Yamssi Cedric, Noumedem Anangmo Christelle Nadia and Vincent Khan Payne

Article Type: Research Article | First Published: 2023/12/09

Intestinal Parasitic Infections (IPIs) are a major public health problem in tropical and subtropical regions. This study aimed to determine the prevalence of intestinal parasites in Yaounde III Subdivision during the COVID-19 pandemic....
 

 Open Access DOI:10.23937/2643-461X/1710074

Case Report: Bee Sting-Associated Meningitis due to S. aureus

Jessica Maria Oliveira Bordinhon, Renata Pinheiro cavallaro de Oliveira, Larissa Vaneska Izidorio Vidal, Samanta Bernardes Cauti, Juliana Pasquini Ferraz Monfardini, Bruno Macedo de Sousa, Thais Marques Sanches Gentil, Marcus Vinícius Landim Stori Milani and Antonio Camargo Martins, MD, PhD

Article Type: Case Report | First Published: 2023/08/11

S. aureus meningitis usually occurs in the postoperative neurosurgical. There are few cases from the community. We report the case of an 83-year-old woman undergoing alternative therapy for rheumatoid arthritis with bee stings on her knee. She was hospitalized with an allergic reaction after the fourth session. She remained in the hospital for 4 days and was discharged in good general condition. Ten days after discharge, the patient returned to the unit with complaints of headache and fever for ...
 

 Open Access DOI:10.23937/2643-461X/1710073

Educational Intervention Package to Increase Knowledge on Minimizing the Delays in Seeking Treatment of Leptospirosis in a District of Sri Lanka

Kumari AMUP, Vidanapathirana J, Amarasekara J and Karunanayake L

Article Type: Research Article | First Published: 2023/07/15

Leptospirosis is a potentially fatal zoonotic infection and often neglected due to lack of knowledge. As an occupational disease, it has become a global concern due to its disease burden in endemic countries and rural areas. The objective of the study was to assess the effectiveness of an educational intervention for knowledge on minimizing the delays in seeking treatment of leptospirosis among farmers in Monaragala District, Sri Lanka. ...
 

 Open Access DOI:10.23937/2643-461X/1710072

Assessment of Prevalence of Communicable and Non-Communicable Diseases in a Rural Community and its Neighborhood in Enugu State, Nigeria: A Cross-Sectional Epidemiological Survey from a Health Outreach

Ogbonna N John Dike, Chinelo N Aguiyi-Ikeanyi, Abdulmuminu Isah, Adaobi U Mosanya, Nkechi J Okonkwo-Uzor, Ginikachukwu N Okeke, Ohagwu M Beatrice-zita, Onyia C Oluebube and Nchekwube Precious Ebubechukwu

Article Type: Original Article | First Published: 2023/07/10

Africa faces a double burden of communicable and chronic non-communicable diseases which have long-term public health impact. This study is to ascertain the disease prevalence, the degree, and the predisposing risk factors of communicable and non-communicable disease in Uvuru, in Uzo-Uwani Enugu State....
 

 Open Access DOI:10.23937/2643-461X/1710071

Examining the Challenges Affecting the Application of Innovative Simulation-Based Teaching and Learning among Teaching Staff in Selected Kenya Medical Training College Campuses Offering Medical Laboratory Sciences in Kenya

Muia Prominah Kavinya, Joyce Lugulu and Priscah Mosol

Article Type: Research Article | First Published: 2023/05/28

Simulation is a teaching learning and assessment strategy used in medical education to prepare medical laboratory students for clinical practice. Simulation-based learning is aimed at bridging the gap between theory and practice through the use of innovative teaching strategies and thus it is considered the best alternative teaching, learning and assessment tool in preparing medical laboratory students for practical and professional life....
 

 Open Access DOI:10.23937/2643-461X/1710070

Effects of Intermittent Preventive Treatment (IPT) of Malaria on the Birth Weight of Babies at Delivery in Dschang, West Region of Cameroon

Sabrina Lynda Kamga, Innocent M Ali, Ghislain Romeo NGANGNANG, KEPTCHEU TD Leonard and PAYNE V Khan

Article Type: Research Article | First Published: March 13, 2023

Malaria is an important public health concern among pregnant women, approximately 32 million of them are at risk annually. According to the World Health Organization (WHO), malaria represents annually more than 10.000 maternal deaths and 200.000 neonatal deaths too. Intermittent Preventive Treatment (IPT) is used to reduce disease in pregnancy and their effects on the newborn. Today the WHO recommends that at least three doses of IPT should be taken by pregnant women during Antenatal Care Visit ...
 

 Open Access DOI:10.23937/2643-461X/1710069

Assessment of the Knowledge, Attitude, Practices and Malaria Prevalence among Undergraduates

Temiloluwa Afolayan, Williams O Tanimowo, Azeez G Ibrahim and Huldah Oduwa

Article Type: Research Article | First Published: March 04, 2023

This study assessed the prevalence of malaria infection, associated risk factors, knowledge and practices about malaria among selected students in Lagos state, Nigeria. The study employed quantitative descriptive cross-sectional design, using pre-tested questionnaires and rapid diagnostic test kits to collect data from 172 University students in Lagos state. Data were analyzed using Statistical Package for Social Sciences (SPSS) version 25....
 

 Open Access DOI:10.23937/2643-461X/1710068

Patient Invaded by 99 Mango Fly Larva - A Case Report

Köhler P, MD, Glosse H, Dogan, Oezguer, MD, Loff S and Staubach R, MD

Article Type: Case Report | First Published: January 30, 2023

We report a 35-year-old patient that presented himself to volunteering doctors in the slums of Nairobi, Kenya. The patient has been suffering of a sensation of crawling on his back and the dorsal side of his arms. Furthermore, he mentioned multiple painful swelling increasing in size. Upon clinical status, multiple noduli was discovered in differing clinical stages....
 

 Open Access DOI:10.23937/2643-461X/1710067

Therapeutic Efficacy of Arthemeter-Lumefantrine (Coartem®) for the Treatment of Uncomplicated Plasmodium falciparum Malaria in Woreta, South Gonder Zone, Amhara Region, Ethiopia

Sintayehu Tsegaye Tseha

Article Type: Research Article | First Published: December 19, 2022

The aim of the study was to investigate the therapeutic efficacy of Coartem® in the treatment of uncomplicated P. falciparum malaria in Woreta Town, South Gonder Zone, Ethiopia. 2240 febrile patients attending the health center were screened and capillary blood was obtained by finger prick. Giemsa stained thick and thin blood smears were prepared and used for parasite density and species identification....
 

 Open Access DOI:10.23937/2643-461X/1710066

Survival and Predictors of Mortality among HIV Infected Adults Receiving ART in Hawassa Comprehensive Specialized Hospital, Sidama Regional State, Ethiopia

Bargude Balta and Amanuel Fanta

Article Type: Research Article | First Published: November 27, 2022

HIV/AIDS continues to be a major global public health issue, having claimed. The rapidly expanding access to antiretroviral therapy (ART) is increasing survival of global HIV epidemic dramatic ways and AIDS-related mortality rates are declining fastly. The aim of this study was to determine survival status and predictors’ of mortality among ART patients attending Hawassa Comprehensive Specialized Hospital 2020....
 

 Open Access DOI:10.23937/2643-461X/1710065

Lassa fever in Nigeria: Social and Ecological Risk Factors Exacerbating Transmission and Sustainable Management Strategies

Sylvester Chibueze Izah, Kurotimipa Frank Ovuru and Matthew Chidozie Ogwu

Article Type: Review Article | First Published: July 24, 2022

With the advent of COVID-19, infectious diseases are increasingly a cause of concern to both national and international governments as well as non-governmental organizations. This review focusses on Lassa fever incidence, prevalence, and socioecological factors influencing the spread and management of the disease in Nigeria using data mined from the Nigeria Centre for Disease Control and other public databases....
 

 Open Access DOI:10.23937/2643-461X/1710063

COVID-19 Vaccine Acceptance and Hesitancy: A Continental Review

Olabode Ebenezer Omotoso, Tolulope Oladimeji, John Oluwafemi Teibo and Ayomide Oluwadarasimi Adebesin

Article Type: Review Article | First Published: June 09, 2022

There are various contributory factors that decide acceptance or ensure hesitancy among the populace which includes: Age, education, gender, residence, household income, marital status, religion, information source, access to vaccine and vaccine equity, etc. Major concerns, barriers, and motivators about vaccination were highlighted....
 

 Open Access DOI:10.23937/2643-461X/1710064

Clinical Profile of the Diagnosis and Treatment of Human Brucellosis in Ghindae Zonal Referral Hospital, Northern Red Sea Region, Eritrea

Esayas T Mehari, MD, Dawit Kidane, Abraham Dawit Jeff, Feven T Mehari, Michael Ghebrezghabiher and Fitsum Kibreab

Article Type: Original article | First Published: June 13, 2022

The study aims to uncover the burden of brucellosis in Ghindae Zonal Referral Hospital, the therapeutic approach used at the hospital, and the outcome of treatment....
 

 Open Access DOI:10.23937/2643-461X/1710062

Telfairia occidentalis as a Potential Lavicide against Human Malarial Vector, Anopheles coluzzi (Diptera: Culicidae): A First Report

Nura Abubakar and Muhammad Mahe Mukhtar

Article Type: Original Article | First Published: April 28, 2022

The eco-friendly nature of plant extracts has made them become sustainable alternative vector control agents. Anopheles mosquitoes serve as the vectors for human malaria. Malaria still kills more than 600,000 individuals every year, 90% of this in sub-Saharan Africa and mostly children under five. In the present study, larvicidal activity of leaf extract of Telfairia occidentalis was evaluated against the malarial vector, Anopheles coluzzi. The adult bloodfed Anopheles mosquitoes were collected ...
 

 Open Access DOI:10.23937/2643-461X/1710060

Impact of a Group-Based Video and Interactive Group Session Addressing Diarrheal Disease, Helminthic and Schistosomiasis Infections, Hypertension and Diabetes on Short and Long- Term Improvement in Knowledge and Healthy Behaviors in Seroconcordant HIV-Negative Zambian Couples

Sharkey, MPH, DrPH (cand), R Parker, MSPH, KM Wall, PhD, K Malama, PhD, W Kilembe, MD, MSc, M Inambao, MD, MPH, A Tichacek, MPH, C Kwok, MPH, N Ahmed, MPH, DrPH, R Burke, MPH, RW Peeling, PhD and S Allen, MD, MPH

Article Type: Original Article | First Published: April 27, 2022

Non-communicable and neglected tropical diseases (NCD and NTD) contribute to high morbidity and mortality in Zambia. While the public health importance of NTD has long been recognized, prevalence of disease remains high. NCD are emerging as causes of morbidity and mortality. Knowledge of risk factors, diagnosis, management, and prevention of NCDs and NTDs in the general population is poor and as a result, low-cost commodities are insufficiently used. Urban couples recruited in five government he...
 

 Open Access DOI:10.23937/2643-461X/1710061

Isothermal Amplification-Based Detection Platforms for Pathogenic Leptospira Species in Flood and Environmental Waters

Rubigilda Paraguison-Alili, Renmar M Dela Cruz, Analiza M Balaga and Winston A Palasi

Article Type: Original Article | First Published: April 27, 2022

Detecting the occurrence of pathogenic Leptospira spp. is vital for public health implications and epidemiological studies. Different isothermal-based techniques ascribed to loop-mediated isothermal amplification (LAMP) to detect Leptospira spp. in black rats and spiked environmental waters were evaluated. In this study, modified platforms were designed to detect the lipL32 gene encoding the major outer membrane lipoprotein of Leptospira spp. Standard and direct dry isothermal technique platform...
 

 Open Access DOI:10.23937/2643-461X/1710059

Performance of GeneXpert in the Diagnosis of Tuberculosis in a Decentralized Area: Example of Hopital De La Paix, in Ziguinchor, Southern Senegal from 2016 to 2018

Kalilou Diallo, Ansoumana Diatta, Bruce Shinga Wembulua, Awa Camara, Habibou Sarr, Mame Ngone Coly, Alassane Diatta and Noel Magloire Manga

Article Type: Research Article | First Published: March 17, 2022

The Xpert MTB/RIF test is one of the innovative responses to the challenges of early diagnosis of tuberculosis and rifampicin resistance. Three years after the arrival of GeneXpert at La Paix hospital, we carried out this study in order to assess its contribution to the diagnostic process. This cross-sectional, descriptive and analytical study focused on suspected tuberculosis patients whose pathological products were analyzed at the unit of microbiology of La Paix hospital of Ziguinchor, Senega...
 

 Open Access DOI:10.23937/2643-461X/1710058

Antimicrobial Resistance Patterns of Pseudomonas aeruginosa in a Vietnamese Tertiary Care Hospital

Thi Ha Vo, PhD, Pharm, Quang Hien Bui, BSc, Pharm, Hoang Hai Nguyen, PhD, MD and Hong Tham Pham, BSc, Pharm

Article Type: Original Article | First Published: March 17, 2022

Vietnam is one of the countries at high alert of antibiotic resistance. This study aimed to evaluate the antimicrobial susceptibility of P. aeruginosa isolates collected from a Vietnamese hospital in 2019. A retrospective review was conducted of all reports of P. aeruginosa isolates from the records of the laboratory of Nhan Dan Gia Dinh Hospital between January 01 2019 to December 31 2019. Of 224 samples, the most common infection from which P. aeruginosa was isolated was pneumonia in hospitali...
 

 Open Access DOI:10.23937/2643-461X/1710057

Understanding the Systemic Effects of COVID-19: Possible Clues to Potential Therapeutic Approaches

Oritoke M Aluko, Saheed A Lawal, Celestine S Reuben, Sikirullai O Jeje and Omamuyovwi M Ijomone

Article Type: Review Article | First Published: February 18, 2022

The novel coronavirus disease (COVID-19) is an infectious disease caused by the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It is an acute respiratory disease that causes life-threatening symptoms. This virus directly or indirectly affects the various systems of the body. In the respiratory system, it causes pulmonary edema, impaired oxygen diffusing capacity, difficulty in breathing, etc. In the nervous system, it causes encephalitis, thrombo-embolitic stroke, Guillan-Barr...
 

 Open Access DOI:10.23937/2643-461X/1710056

Analysis of IgG Responses to P. falciparum Antigens MSP1, MSP4-20 and MSP4-40 during Severe Malaria in Dakar, Senegal

Bruce Shinga Wembulua, Kalilou Diallo, Folly Mawulolo Gaba, Babacar Mbengue and Louise Fortes

Article Type: Original Article | First Published: February 07, 2022

Antibodies to merozoite surface antigens (MSPs), the primary targets of malaria vaccine research, are associated with low malaria morbidity. However, few studies have looked at the implications of their variations on the evolution of clinical-biological forms of severe malaria. This cross-sectional, prospective, and analytical study evaluates by ELISA the IgG responses directed against the antigens MSP1, MSP4-20 and MSP4-40 of P. falciparum during severe malaria in patients hospitalized in the i...
 

 Open Access DOI:10.23937/2643-461X/1710055

Malaria Parasite Infection and its Effect on Packed Cell Volume among Pregnant Women in Zaria, Nigeria

Obed Abigail, Maryam Aminu and Umar Abdullahi

Article Type: Research Article | First Published: December 10, 2021

Malaria in pregnancy is a major public health challenge and priority, because it is a health risk for the mother and her fetus. This study was aimed at determining the prevalence of malaria parasites and its effect on packed cell volume (PCV) among pregnant women attending antenatal clinic in Zaria. A total of 102 pregnant women on ante-natal visit in three different hospitals were enrolled and questionnaires were administered to them to obtain data on some risks and sociodemographic factors tha...
 

 Open Access DOI:10.23937/2643-461X/1710054

Human African Trypanosomiasis in the Northern Region of Zimbabwe: Reported Cases, Health Implications and the Way Forward

Amon Munyenyiwa, Moses Zimba, Mascelini Jenipher Mutsaka-Makuvaza, Portia Manangazira, Tamuka Nhiwatiwa, Charles Maponga and Nicholas Midzi

Article Type: Review Article | First Published: November 10, 2021

Human African Trypanosomiasis (HAT) keeps resurfacing in Zimbabwe raising the need to capacitate the health system with adequate tools to eliminate the disease as a public health threat in the country. The aim of this study is to document recorded HAT cases in Zimbabwe as well as highlighting the impact of the disease and potential control strategies. Published research articles with main focus on HAT in Africa and Zimbabwe were used. The country recorded zero cases of HAT from 1998 to 2004, con...
 

 Open Access DOI:10.23937/2643-461X/1710053

Antioxidant Status of Children Infected with Plasmodium falciparum Malaria in Kebbi Metropolis, Northwestern Nigeria

Mode Muhammad Abduljalil, Mu’azu Gusau Abubakar and Muhammad Abdulmalik Danjuma

Article Type: Original Research | First Published: October 20, 2021

Malaria is a global life aggressive disease caused by the Plasmodium parasite to a host after infected anopheles mosquito leading to release of free radicals which have the capacity to induce oxidative stress. This study was carried out to assess the effect of malaria parasite (Plasmodium falciparum) on some antioxidants (vitamins A, C, E and reduced glutathione) and lipid peroxidation marker (MDA) in children attending Sir Yahaya Memorial Hospital, Birnin Kebbi, Kebbi State, Nigeria. Blood samp...
 

 Open Access DOI:10.23937/2643-461X/1710052

COVID 19 and Neglected Tropical Diseases in Africa: Perspectives from Ghana

Emmanuella Nzeribe, Melody Okereke, Isaac Olushola Ogunkola, Mashkur Abdulhamid Isa, Yusuff Adebayo Adebisi and Don Eliseo Lucero-Prisno III

Article Type: Commentary | First Published: August 28, 2021

Since the World Health Organization declared COVID-19 as a public health emergency, the attention of the global community has been shifted towards interventions and efforts to curb the pandemic at the detriment of other diseases, including Neglected Tropical Diseases (NTDs). Prior to the emergence of COVID-19 in Africa, Ghana has recorded some progress in the economy which has translated to an overall expectation of a decline in the incidence of NTDs and other poverty-related diseases in the cou...
 

 Open Access DOI:10.23937/2643-461X/1710051

Factors Affecting the Spatial Distribution of Visceral Leishmaniasis in an Urban Area of Recent Emergence in Inner Brazil

José Cláudio Simão, Cassiano Victória and Carlos Magno Castelo Branco Fortaleza

Article Type: Field Research | First Published: August 21, 2021

Study of the spatial distribution of general VL and VL-HIV coinfection in the city of Bauru - SP, Brazil between 2003 to 2016. The cases were georeferenced and attributed to the Census sectors using demographic, socioeconomic and urban infrastructure predictors. The incidence in these sectors was analyzed in univariate and multivariate one-step Poisson regression models. The cumulative incidence rates of LV and LVHIV (per 100,000 inhab.) In this period were 131.1 and 19.7, respectively. In the u...
 

 Open Access DOI:10.23937/2643-461X/1710050

In Vitro Evaluation and Molecular Docking Studies of Aryl- Substituted Imidazoles against Leishmania Amazonensis

Julio Alberto Rojas Vargas, América García López, Aliesky Ramírez Vargas, Lianet Monzote Fidalgo and Matheus Froeyen

Article Type: Research Article | First Published: July 23, 2021

Leishmaniasis is a disease caused by the protozoan Leishmania that is considered one of the causes of death from parasitic infection worldwide. Looking for the right chemotherapy against leishmaniasis has been difficult because of the high toxicity of the most effective drugs. This disease is considered among the 13 unattended diseases worldwide according to the World Health Organization (WHO). In the present work, the leishmanicidal activity against L. amazonensis promastigote and cytotoxicity ...
 

 Open Access DOI:10.23937/2643-461X/1710049

Myelitis due to Varicella-Zoster Infection in an Adult Immunocompetent Patient at Yalgado Ouedraogo University Teaching Hospital (Burkina Faso)

Dabilgou AA, Dao SBA, Dravé A, Kyelem M JA, Napon C and Kaboré J

Article Type: Case Report | First Published: June 30, 2021

Varicella Zoster Virus (VZV) is a ubiquitous virus and is causing both diseases of varicella and herpes zoster. VZV reactivation may lead to neurological complications, including transverse myelitis. However, transverse myelitis caused by VZV reactivation is rare in immunocompetent patients. We reported a case of transverse myelitis caused by VZV in an immunocompetent young patient. A 42-year-old man was presented to the Neurology department in June 2019 with the complaints of cutaneous rash, lo...
 

 Open Access DOI:10.23937/2643-461X/1710047

Dengue Fever: Ophthalmological Perspective

Hernandez-Delgado MA, Salvador-Galvez B and Valdez- Garcia JE

Article Type: Review Article | First Published: April 24, 2021

Dengue fever is a highly prevalent zoonotic disease. This virus endangers 3.9 billion people, with no less than 390 million infections annually. Dengue has a broad spectrum of clinical manifestations; from completely asymptomatic to life threatening complications. This review discusses the relevance of dengue in current medical practice as well as the scarcely known ophthalmological complications. We aimed to first describe the epidemiology, viral characteristics, transmission and global distrib...
 

 Open Access DOI:10.23937/2643-461X/1710046

Performance Evaluation of Malaria HRP-2 Rapid Diagnostic Test among Febrile Patients with Malaria in Iwo, Osun State, Nigeria

Oladosu Oladipo O, Adedokun Victoria A, Adeniyi Akinkunle V and Oyibo Wellington A

Article Type: Original Research | First Published: March 31, 2021

Diagnosis of malaria is a fundamental component of malaria case management. Parasitological confirmation of malaria before treatment was recommended for endemic countries. Microscopy diagnosis of malaria, the gold standard as constraints such as: level of expertise, quality of equipment and reagents may lead to misdiagnosis. The histidine rich protein 2 (HRP-2) based rapid diagnostic test (RDT) detects Plasmodium falciparum only. We therefore evaluated the performance of malaria HRP-2 rapid test...
 

 Open Access DOI:10.23937/2643-461X/1710045

Resistant Hypoglycaemia - A Unique Presentation of Congenital Dengue

Narendra Rai, Neha Thakur and Divya Pandey

Article Type: Case Report | First Published: February 05, 2021

Vertical transmission of dengue is uncommonly reported. There have been occasional case reports of congenital dengue with thrombocytopenia and myocarditis. This is the first case report of refractory hypoglycaemia in congenital dengue. We are reporting a case of congenital dengue in a primigravida who developed dengue fever in last trimester of pregnancy. She underwent an emergency caesarean section in view of decreased foetal movements. Post-operative she developed post-partum haemorrhage and p...
 

 Open Access DOI:10.23937/2643-461X/1710044

Addressing Schistosomiasis in a Community in Nigeria: A Theoretical Approach

Anyanti J, Akuiyibo S , Onuoha O, Nwokolo E, Atagame K and Braide EI

Article Type: Original Research | First Published: January 11, 2021

Schistosomiasis is one of several Neglected Tropical Diseases considered a major public health problem that affects tropical and sub-tropical countries. Residents of Gwako, a rural community in Nigeria’s Federal Capital Territory (FCT) lack access to potable water supply with community members resorting to a dirty stream - an unhygienic water source. It is estimated that significant proportions or all Gwako residents are infested with schistosomiasis with very high transmission rates. Resident...
 

 Open Access DOI:10.23937/2643-461X/1710042

Field Comparison between Blood Immunochromatographic Card Test and Microscopy in Diagnosis of Bancroftian Filariasis in Northern Taraba State, Nigeria

Elkanah OS, Elkanah DS, Wahedi JA, Kela SL, Samaila AB and Madara AA

Article Type: Research Article | First Published: December 24, 2020

Diagnosis of filariasis is important for Programme Managers and Physicians. This study was undertaken to determine the prevalence of lymphatic filariasis in eleven communities of Northern Taraba State. The study employed standard parasitological techniques for diagnosis, and the use of Immunochromatographic Card Test (ICT) to detect Circulating Filarial Antigen (CFA). Chi Square was used to compare and test for differences in infections among communities. 294 persons were examined, and 31.29% we...
 

 Open Access DOI:10.23937/2643-461X/1710041

Animal Trypanosomiasis in Cattle of Good Body Condition Score in the Adamawa Region of Cameroon: Hematological and Immunological Implications

Ebanga Echi Joan, Amadoh Jude Akumbu, Farikou Oumarou, Abba Samuel and Oumar Mahamat

Article Type: Research Article | First Published: December 23, 2020

The control of animal trypanosomiasis consists, amongst other things, the punctual treatment of new cases, primarily diagnosed by pastoralists on the basis of clinical signs. This practice suggests that many healthy infected animals are left untreated. In this study, animal trypanosomiasis in cattle of good body condition score was evaluated, the existence of polyclonal anti-trypanosome (Anti-tryps) and its serotherapy implications were discussed. From January to March 2020, the study was carrie...
 

 Open Access DOI:10.23937/2643-461X/1710040

Knowledge and Utilisation of Long Lasting Insecticidal Nets and Intermittent Preventive Treatment of Malaria in Pregnancy among Pregnant Women and Children Under Five Years in Selected Communities of Ogun State, Nigeria

Adeneye AK, Jegede AS, Mafe MA and Nwokocha EE

Article Type: Research Article | First Published: November 30, 2020

There are very few evidence from studies on the knowledge, accessibility and use of LLIN and IPTp in communities of Ogun State following the promotion of the malaria control strategies across the country. This study was therefore conducted to examine the knowledge, accessibility and use of malaria control strategies that include long-lasting insecticidal nets (LLINs), and intermittent preventive treatment of malaria in pregnancy (IPTp) within the context of rolling back malaria in Ogun State, Ni...
 

 Open Access DOI:10.23937/2643-461X/1710039

Parasitaemia in Asymptomatic Bantu and Baka Pygmy People Living in the East Region, Cameroon

Gangueu Djape Clotilde Diane, Yondo Jeannette, Noumedem Anangmo Christelle Nadia, Nkouayep Vanessa Rosine, Atiokeng Tatang Rostang Joel and Mpoame Mbida

Article Type: Research Article | First Published: November 11, 2020

Asymptomatic malaria constitutes a silent threat to an efficient malaria control strategy. The aim of this study was to assess the level of malaria parasitaemia tolerated by asymptomatic individuals in Baka pygmies and the Bantus of the East Region, Cameroon. A community-based cross-sectional study was conducted among asymptomatic Bantu and Baka pygmies from 6 months aged to 76-years-old. A questionnaire was used to collect information from 1032 consenting participants about ethnicity, gender, a...
 

 Open Access DOI:10.23937/2643-461X/1710038

Prevalence, Intensity and Effects of Anthelminthic Drug Efficacy on Gastrointestinal Helminths in Nkambe, North West Region Cameroon

Bup R Manjuh, Khan P Vincent, Noumedem AC Nadia and Yamssi Cedric

Article Type: Research Article | First Published: November 11, 2020

Parasitic infections are major health problems worldwide. These parasitic infections are caused by Helminths and Protozoans. High prevalence is mostly in people with low socio-economic status and this is due to lack of hygiene and sanitation. This study aimed at providing systemic data that will be used to determine the prevalence, intensity and the efficacy of anthelminthic drugs (Albendazole 400 mg and Mebendazole 500 mg) against gastrointestinal helminths among the population of Nkambe. Quali...
 

 Open Access DOI:10.23937/2643-461X/1710037

Detecting Mycobacterium ulcerans in Clinical Specimens from Ghana: Comparative Evaluation of BU-LAMP and IS2404 PCR

Enoch Aninagyei, Rufai Tanko, Comfort Dede Tetteh, Kofi Adjei Ntiri, Mathias Dongyele, Alex Boye and Desmond Omane Acheampong

Article Type: Research Article | First Published: October 19, 2020

Conventional and nested polymerase chain reaction (PCR), and loop-mediated isothermal amplification (LAMP) have been used to identify Mycobacterium ulcerans in separate studies and different specimens. However, the sensitivities of these three techniques have not been compared in a single study. Samples were collected from patients suspected of Buruli ulcer disease (BUD) in Southern Ghana. Ulcerative and non-ulcerative forms of the disease were swabbed and aspirated respectively. Insertion seque...
 

 Open Access DOI:10.23937/2643-461X/1710036

Prevalence of Geo-Helminths and Evaluation of Single Dose of Albendazole (400 mg) among School Children in Poumougne, Western Region, Cameroon

Yamssi Cedric, Kamga Simo Sabrina Lynda, Noumedem Anangmo Christelle Nadia and Vincent Khan Payne

Article Type: Research Article | First Published: October 09, 2020

Soil Transmitted Helminths (STHs) also called Geo-helminths are endemic in rural areas of developing countries. This study was conducted to determine the prevalence of Geo helminths, their risk factors and an evaluation of a single dose of Albendazole 400 mg among infected School Children. Three High schools and Colleges, three Primary schools and a Nursery School were selected at random for sample collection. Stool was collected from each subject and analyzed using floatation technique and Mc- ...
 

 Open Access DOI:10.23937/2643-461X/1710035

Daily Moxifloxacin, Clarithromycin, Minocycline, and Clofazimine in Nonresponsiveness Leprosy Cases to Recommended Treatment Regimen

Francisco Bezerra de Almeida Neto, MD, Rebeca Daniele Buarque Feitosa, OT and Marqueline Soares da Silva, RN

Article Type: Case Series | First Published: October 07, 2020

retrospective, observational case series study was conducted of 4 patients with multibacillary leprosy who presented to a specialized Leprosy health care. Between July 1, 2018, and July 31, 2020, they were treated with moxifloxacin, clarithromycin, minocycline, and clofazimine. A literature review was conducted on the clinical features and treatment of nonresponsiveness leprosy cases to regular MDT-MB. Four patients (3 male; mean [SD] age at treatment, 41 [22.6] years) with nonresponsiveness lep...
 

 Open Access DOI:10.23937/2643-461X/1710034

SARS-CoV-2 Infection & Cardiology: Overview on Renin-Angiotensin- Aldosterone System Inhibition

Gustavo Henrique Sumnienski Bertoldi, Rafael M Ronsoni, MD, MsC and Marcus Vinicius Magno Goncalves, MD, PhD

Article Type: Review Article | First Published: July 04, 2020

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a coronavirus strain, and its main way to get access to the cells is via the angiotensin converting enzyme (ACE2) and causes the Coronavirus Disease 2019 (COVID-19). ACE2 is an important enzyme in the pathogeneses of hypertension. For the treatment of hypertension, it is commonly used angiotensin II receptor blockers (ARBs) and angiotensin II converting enzyme inhibitors (ACEIs). It is clear that there is a lot of uncertainty an...
 

 Open Access DOI:10.23937/2643-461X/1710033

Malaria Control Efforts in the Era of COVID-19: A Call to Remain Vigilant in Endemic Areas

Eliningaya J Kweka

Article Type: Commentary | First Published: June 19, 2020

Success in controlling malaria has been reported across the world mainly through the use of long-lasting insecticidal nets, indoor residual spray, and appropriate diagnosis and treatment. However, in the era of COVID-19, more attention has been shifted to cases and mortality caused by the SARS-CoV-2 virus, which are jeopardizing the continuity of efforts attained so far in malaria control. This commentary proposes alternatives to be adopted during the COVID-19 pandemic to maintain the attained m...
 

 Open Access DOI:10.23937/2643-461X/1710032

Epidemiology of Intestinal Parasitism in Schoolchildren Treated at the Primary Health System. Havana 2020

Osvaldo Batista Rojas, MSc

Article Type: Research Article | First Published: June 04, 2020

An observational, descriptive and cross-sectional study was carried out; the universe of study was represented by all schoolchildren from six Primary Schools in Marianao during the period from August 2018 to January 2020 with the clinical and microbiological diagnosis of intestinal parasitosis and they were treated at Five Family Medical Offices. There was a predominance of the female sex for 51.4%. With greater predominance of the age group of 5 to 7 years for 33.8%, abdominal pain was the most...
 

 Open Access DOI:10.23937/2643-461X/1710031

SARS-Cov-2 Infection and Cardiology: Beware of Myocarditis

Marco Antonio Machado Schlindwein, Leticia Caroline Breis, Isabelle Pastor Bandeira, Rafael M Ronsoni, MD, MsC, Clizenaldo Torres, MD and Marcus Vinicius Magno Goncalves, MD, PhD

Article Type: Commentary | First Published: May 13, 2020

The emergence of SARS-CoV-2 is a challenge in the actual medical scenario. Besides the classical lung and respiratory disease, patients infected with the virus can present with cardiac injury, and pathogenic mechanisms point to direct infection of the heart. In this paper, we seek to show the correlation between cardiology and SARS-CoV-2 infection, especially with regard to myocarditis, which has been shown to be one of the complications in COVID-19. SARS-CoV-2 is the virus responsible for coron...
 

 Open Access DOI:10.23937/2643-461X/1710030

Parasites Intestinal: Level of Knowledge and Envisions Measures Mothers of Schoolchildren of Marianao Municipality

Osvaldo Batista Rojas, MSc

Article Type: Research Article | First Published: April 24, 2020

To determine the association between the level of knowledge about intestinal parasitosis and preventive measures in mothers of parasitized schoolchildren between the ages of 5 and 11 years of the Marianao municipality in Havana in 2019. An observational, analytical, crosssectional study that included 195 mothers of schoolchildren between the ages of 5 and 11 years attended in the four Family Medical Offices of Marianao, Havana. Age, marital status, educational level, occupation, level of knowled...
 

 Open Access DOI:10.23937/2643-461X/1710029

A Prospective Analysis of Otomycosis in a Tertiary Care Hospital

Shuaib Kayode Aremu, Kayode Rasaq Adewoye and Tayo Ibrahim

Article Type: Original article | First Published: April 08, 2020

The study was conducted in the Ear, Nose, and Throat (ENT) department of Federal Teaching Hospital Ido-Ekiti, which is a tertiary care hospital in Ekiti state, Nigeria. The study involved 275 patients above the age of 10, who presented in the ENT department over 5 years period and were clinically diagnosed cases of otomycosis. Certain patient demographics such as age, gender, and clinical presentations were recorded along with possible risk factors and clinically observed findings. Microbiologic...
 

 Open Access DOI:10.23937/2643-461X/1710028

Results of an Intervention Model in Intestinal Parasitosis in Parents Havana 2019-2020

Osvaldo Batista Rojas, MSc

Article Type: Research article | First Published: February 20, 2020

An educational intervention study on intestinal parasitism was carried out in parents of parasitized children of Capitan San Luis de Marianao Elementary School, Havana in the period May 2018-2019, with the purpose of modifying the knowledge in these parents against some hygienic- sanitary aspects in order to reduce the incidence of disease through the application of a program of educational activities. Knowledge was determined through the use of a structured questionnaire. And social activities ...
 

 Open Access DOI:10.23937/2643-461X/1710027

Early Blood Brain Barrier Traversal by Trypanosoma Brucei Brucei Strains: A Phenomenon of Laboratory Strains or Field Strains as Well?

Monica Namayanja, Gloria Grace Akurut and George W Lubega

Article Type: Short Communication | First Published: February 08, 2020

Trypanosoma brucei brucei in mice, the experimental model of African Trypanosomiasis, is known to begin crossing the blood-brain barrier between 9-13 days post-infection, which is also considered the commencement of the late stage of the disease. A few recent reports however, reported traversal as early as two hours to a few days. In these reports laboratory strains were used thus this study sought to find out if this early brain invasion is phenomenon of laboratory strains or also field isolate...
 

 Open Access DOI:10.23937/2643-461X/1710026

Utility of Mean Platelet Volume to Predict Significant Thrombocytopenia and Complications in Dengue

Anupam Brahma, MBBS, Prasit Kumar Ghosh, MD, Utpal Goswami, MD and Saswati Majumdar, MD

Article Type: Original Article | First Published: December 11, 2019

Dengue fever is one of the most important emerging infectious diseases constituting important contribution in global burden of disease. Platelet transfusion is required in the patients when they develop Dengue Hemorrhagic Fever (DHF) or thrombocytopenia below 20,000/ cu.mm without hemorrhage. Serial platelet counts are used to monitor the patients. In this study we investigated whether Mean Platelet Volume (MPV) could be used as a tool to predict development of significant thrombocytopenia, DHF ...
 

 Open Access DOI:10.23937/2643-461X/1710025

Assessment of Mitochondrial and Nuclear Genes for Molecular Detection during Early Trichinella spiralis Infection

Silvio J Krivokapich, Cinthia L Gonzalez Prous, Graciana M Gatti and Patricia A Arbusti

Article Type: Original Article | First Published: August 31, 2019

Early serological diagnosis of trichinellosis is affected by a long-term immunological "silent" period following infection. This emphasises the need for the development of sensitive diagnostic methods to be used when antibodies cannot be detected. In this study, we assessed the usefulness of three DNA sequences as a direct diagnosis method to detect early infection with Trichinella spiralis in peripheral blood by SYBR green real-time PCR using a murine model. Primers were designed from a nuclear...
 

 Open Access DOI:10.23937/2643-461X/1710024

Results of the First Phase of Educational Intervention in Schoolchildren of Marianao Municipality on Intestinal Parasitosis 2017-2019

Osvaldo Batista Rojas, MSc

Article Type: Original Research | First Published: August 31, 2019

An intervention study was carried out, quasi-experimental, retro-prospective with the students of the Primary School "Hugo Camejo" and their parents in the period 2017-2019. The universe was constituted by 627 students and the sample by the 83 schoolchildren of 4th grade, with the objective of developing an intervention strategy to increase the level of knowledge about intestinal parasitosis. Reaching the following conclusions: Only half of the children before the intervention had adequate hygie...
 

 Open Access DOI:10.23937/2643-461X/1710023

Canine and Human Leishmaniasis: Disease Progression to Brazilian Urbanized Areas

Danilo C Miguel and Danilo C Guarnier, DVM

Article Type: Mini Review | First Published: July 17, 2019

Leishmaniasis is a complex disease considered one of the most neglected tropical diseases of the world. The importance and role of domestic dogs and wild canids as a source of leishmaniasis infection is well recognized. The present mini-review discusses a series of epidemiological studies that reinforce the need to understand the role of reservoirs and vectors in the expansion of leishmaniasis to Brazilian urbanized areas, as Brazil is a country of continental dimensions and endemic for leishman...
 

 Open Access DOI:10.23937/2643-461X/1710021

Causal Relationship of Wastewater Management and Morbidity of Diseases Related to Wastewater in Colombia

Juan Pablo Rodríguez Miranda

Article Type: Short Communication | First Published: May 30, 2019

The causal relationship between environmental pollution and specifically the lack of adequate environmental sanitation, in the context of the elimination of excreta and solid waste disposition on site guaranteed for this purpose, conceives a high risk in the proliferation of vectors and therefore proportional generation morbidity in diseases of a hydric nature that directly or indirectly affects the population....
 

 Open Access DOI:10.23937/2643-461X/1710020

Use of an Antigen Excreted (Sode) in the Search for Antibodies Anti-Trypanosoma Cruzi in Sera from Pediatric Population of the State of Queretaro, Mexico

Maria Elena Villagran-Herrera, Manuel Sanchez-Moreno, Jose Alejandro Martinez-Ibarra, Ricardo Francisco Mercado-Curiel, Adriana Jheny Rodriguez-Mendez, Javier Avila-Morales, Maria del Carmen Aburto-Fernandez, Nicolas Camacho-Calderon and y Jose Antonio de Diego-Cabrera

Article Type: Research article | First Published: May 10, 2019

The acute phase of Chagas disease can occur at any age, however the pediatric population is usually the most affected (from one to 15 years), so it is very important to detect and treat it as soon as possible to try to eliminate the circulating parasite. The main objective of this research is to present the first seroepidemiological study of the infection by Trypanosoma cruzi, carried out to students of school age of both urban and rural primary schools in the State of Querétaro and at the same...
 

 Open Access DOI:10.23937/IJTD-2017/1710019

Plasmodium falciparum Infection among Febrile Patients Attending a Tertiary Healthcare Facility in Central Nigeria: Prevalence, Hematologic and Sociodemographic Factors

Yohanna Jemimah, Oti Victor, Amuta Elizabeth, Philip Akpu and Anizoba Lynda

Article Type: Research article | First Published: April 04, 2019

Plasmodium falciparum infection remains a leading cause of global morbidity and mortality, causing about 3,000 daily deaths. This study intended to document the prevalence, and the associated factors of P. falciparum infection among febrile patients attending Federal the Medical Centre Keffi, Nigeria. After ethical clearance, 400 whole blood samples were collected from patients who gave informed consent and completed a self-structured questionnaire from July 2015 through January 2016. The blood ...
 

 Open Access DOI:10.23937/ijtd-2017/1710018

Insecticidal Activities of Chromolaena odorata and Vernonia amygdalina leaf extracts against Anopheles gambiae [Diptera: Culicidae]

Ileke Kayode David and Olabimi Isaac Omotayo

Article Type: Original Research | First Published: March 18, 2019

Female Anopheles mosquitoes are the vectors of human malaria. The use of chemical insecticides for vector control has hampered with environmental pollution and insect. This suggests the need for the development of more potent and environment-friendly insecticides for effective control of malaria. This research investigated the larvicidal, pupicidal and adulticidal activities of Chromolaena odorata and Vernonia amygdalina leaf extracts against....
 

 Open Access DOI:10.23937/ijtd-2017/1710017

The Efficacy of Three Indigenous Plants (Tetrapleura tetraptera, Bridelia ferruginea and Azadirachta indica) as Plant Derived Molluscicides against Fresh Water Snails

Afolabi Olajide Joseph, Ojo Babatunde David and Simon-Oke Iyabo Adepeju

Article Type: Original Article | First Published: March 13, 2019

Schistosomiasis is a parasitic disease transmitted by fresh water snail infected with the Schistosoma parasites. The disease is endemic in many parts of Asia, Africa, and South America affecting people who are unable to avoid contact with water, either because of their profession or because of lack of reliable source of safe water for drinking, washing and bathing. The study focused on the molluscicidal activities of the oil extracts of Tetrapleura tetraptera, Bridelia ferruginea and Azadirachta...
 

 Open Access DOI:10.23937/ijtd-2017/1710016

The Influence of Human T-Lymphotropic Virus 1 on Patients Coinfected by the Helminth Strongyloides stercoralis

Larissa Rodrigues Bosqui, Taylon Felipe Silva, Raquel Arruda Sanfelice, Lais Fernanda Machado, Erika Caroline Steinle, Bianca Arranzato Bertasso, Marina Leticia Rezende Mantovani, Gabriela de Alcantara Dalevedo, Milena Menegazzo Miranda-Sapla, Ivete Conchon-Costa, Wander Rogerio Pavanelli, Francine Nesello Melanda and Idessania Nazareth Costa

Article Type: Review Article | First Published: February 09, 2019

Strongyloides stercoralis is the helminth which causes strongyloidiasis, a neglected disease, with a global prevalence estimated at 60 million people infected, principally in tropical regions. The parasite’s proliferation occurs mainly in immunosuppressed hosts, in particular, patients carrying Human T-lymphotropic virus 1 (HTLV-1), which is responsible for the infection of cells of the immune system. As a result, we aimed to identify and discuss clinical and pathological aspects of infection ...
 

 Open Access DOI:10.23937/ijtd-2017/1710015

Excavata-Kinetoplastea Trypanosomatidae Parasites and the Interaction with their Hosts

Sylvia Ortiz and Aldo Solari

Article Type: Review Article | First Published: February 06, 2019

Kinetoplastea Trypanosomatidae are unicellular flagellated parasites of different kind of hosts. They cause diseases in plants, animals and humans. These parasites are transmitted by insect vectors in a wide range of geographic areas. In this communication we review the interactions between trypanosomatid parasites, their hosts and thoughts about their impact on environmental health, especially in those regions where hosts are natural reserves of many species. The interactions of these parasites...
 

 Open Access DOI:10.23937/ijtd-2017/1710014

Prevalence of Plasmodium Falciparum among Nigerians in Abuja and Central States: A Comparative Analysis of Sensitivity and Specificity Using Rapid Diagnostic Test and Microscopy as Tools in Management of Malaria

Peter Asaga Mac, Hussaini Fatima Asheadzi, Amuga Gideon, Prerna Thaker and Philomena Airiohuodion

Article Type: Research Article | First Published: January 30, 2019

A cross-sectional study of 403 consenting healthy individuals who came to National hospital, Abuja and Nasarawa State University hospital, Keffi for medical examination were recruited from April 2017 through July 2017. The socio-demographic charactersitics of each participant was obtained through oral consultation. Information collected included the sex, age, occupation and locality to which they belonged. The gold standard tool (microscopy) and RDTs were used to determine the prevalence of mala...
 

 Open Access DOI:10.23937/ijtd-2017/1710013

Macrophage's Arsenal in the Battle against Zaire EBOLA Virus

Michelino Di Rosa and Lucia Malaguarnera

Article Type: Research Article | First Published: January 25, 2019

Over forty years of extensive research has not yet solved the complexity of Ebola pathogenesis leading to a continued need for a successful cure. This virus has evolved different strategies to counteract immune responses as they are unreceptive to a large portion of the known antiviral drugs and there is no valid treatment as to date for disease created by this pathogen. A plethora of evidences have revealed that monocytes/macrophage contribute significantly in viral pathogenesis....
 

 Open Access DOI:10.23937/ijtd-2017/1710012

Pulmonary Strongyloidiasis in a Patient with Terminal Pulmonary Syndrome in Manabi Province, Ecuador: A Report Case

Juan Carlos Alava, Susana Alava and Juan Jose Alava

Article Type: Case Report | First Published: December 08, 2018

Strongyloides stercoralis is a common nematode causing intestinal parasitosis in the Ecuadorian population, but cases of lung infection by this helminth have not been documented in Ecuador. We document the first case of pulmonary strongyloidias is caused by S. stercoralis filariform larvae in a male patient from Manabí Province (Ecuador), showing clinical symptoms of terminal pulmonary syndrome. Previous to the decease of the patient, the larvae were identified by the direct smear method of a f...
 

 Open Access DOI:10.23937/ijtd-2017/1710011

Detection of Intestinal Parasites Transmitted Mechanically by House Flies (Musca domestica, Diptera: Muscidae) Infesting Slaughterhouses in Khartoum State, Sudan

Ahmed Mohammed Al-hassan Ibrahim, Hafiz Hassan Shebeir Ahmed, Rehab AbdElgadir Adam, Ayman Ahmed and Arwa Elaagip

Article Type: Original Article | First Published: November 19, 2018

The housefly, Musca domestica, is a common household pest known to transmit human diseases like pathogenic bacteria, protozoa, metazoan, fungi and viruses. Apart from they are also responsible for transmitting intestinal parasites, which when outbreaks occur, could wreak havoc on both man and animals. The importance of house fly in disease transmission prompted this study to investigate the presence of intestinal parasites transmitted mechanically by houseflies that infested slaughterhouses in c...
 

 Open Access DOI:10.23937/ijtd-2017/1710010

High Prevalence of Epilepsy in Onchocerciasis Endemic Communities of Ngie: Lack of Association with Taeniasis but Strong Indicators of Hereditary Factors and Characteristics of Onchocerciasis Associated Epilepsy Observed

Raphael Awah Abong, Fongoh Ayong Hassan, Tatsinkou Betrand Fossi, Peter Ndefon, Theresa Nkuo-Akenji, Samuel Wanji and Anong Damian Nota

Article Type: Original Article | First Published: November 12, 2018

Epilepsy, a neurological condition which affects individuals of all ages has been widely reported to be caused by parasitic, fungal, bacterial or viral infectious diseases of the Central Nervous System (CNS). Taenia solium infection otherwise known as neurocysticercosis in taeniasis endemic zones, Onchocerca volvulus infection in onchocerciasis meso/hyperendemic areas in Africa and other infectious agents have been highly incriminated in different parts of the world. Epilepsy remains an importan...
 

 Open Access DOI:10.23937/ijtd-2017/1710009

Acute Myopericarditis an Uncommon Presentation of Severe Leptospirosis - A Case Report and Literature Review

Cavalcanti S, L Lerena V and Gomez C

Article Type: Case Report | First Published: October 27, 2018

Cardiovascular involvement by Leptospira is infrequent. However the statistics are under estimated. This paper reports a case of a 39 years old male, who works as a Marine and had traveled to a tropical endemic area for Leptospira in Peru. He was initially admitted with fever, headache and myalgias. He was diagnosed of Leptospirosis (Ig M positive and MAT positive) and malaria and receive specific treatment for both diseases (Doxycycline, Cloroquine, Primaquine). Ten days later he was readmitted...
 

 Open Access DOI:10.23937/ijtd-2017/1710008

A Qualitative Ecohealth Model of Dengue Fever (DF) in Bandung, Indonesia

Titik Respati, Yudi Feriandi, Ermi Ndoen, Ardini Raksanegara, Heni Djuhaeni, Asep Sofyan and Pat Dale

Article Type: Original Article | First Published: October 12, 2018

Dengue Fever (DF) is a serious disease in Indonesia. The sustainability of a DF prevention program remains constrained despite continuing education programs and community participation efforts. Identifying the issues related to the cause of the disease is a major factor in its control. In this study we try to understand the complexity of the management of the disease. We apply an eco-health approach to explore DF management in Bandung city, West Java, an area of high DF incidence. A qualitative ...
 

 Open Access DOI:10.23937/ijtd-2017/1710007

Serological Evidence of Dengue and Chikungunya Exposures in Malian Children by Multiplex Bead Assay

Delynn M Moss, Matthew T Whitney, Anna N Chard, Victoria Trinies, Seydou Doumbia, Christin H Goodman, Stevan Bullard, Ryan E Wiegand, Matthew C Freeman, Patrick J Lammie and Gwong-Jen Chang

Article Type: Research Article | First Published: October 11, 2018

We opportunistically included a chikungunya envelope 1 recombinant virus antigen (CHIKV E1), a dengue 2 virus-like protein (DENV-2 VLP), and a DENV-3 VLP in a multiplex bead assay (MBA) for serological assessment involving improvements in water, sanitation, and hygiene for students attending 42 elementary schools in southern Mali in Western Africa. From students attending grades 1-6,805 dried blood spots (DBS) were collected. Immunoglobulin (Ig) G was eluted from the DBS and was probed for respo...
 

 Open Access DOI:10.23937/IJTD-2017/1710006

Extrapulmonary Tuberculosis: Update on the Epidemiology, Risk Factors and Prevention Strategies

Houda Ben Ayed, Makram Koubaa, Chakib Marrakchi, Khaoula Rekik, Fatma Hammami, Fatma Smaoui, Mariem Ben Hmida, Sourour Yaich, Imed Maaloul, Jamel Damak and Mounir Ben Jemaa

Article Type: REVIEW ARTICLE | First Published: September 03, 2018

Tuberculosis (TB) is one of the major public health threats, competing with the human immunodeficiency virus (HIV) as the cause of death due to infectious diseases worldwide. Extrapulmonary tuberculosis (EPTB) contributes to the burden of disease and does not receive specific attention in international control strategies. We aimed to give an update on the current epidemiological data of EPTB, to describe its clinical spectrum, to identify the main risk factors and to propose effective preventive...
 

 Open Access DOI:10.23937/ijtd-2017/1710005

Development of Vaccination against Fungal Disease: A Review Article

Gebrehiwet Tesfahuneygn and Gebremichael Gebreegziabher

Article Type: Review Article | First Published: August 25, 2018

Vaccines have been hailed as one of the greatest achievements in the public health during the past century. So far, the development of safe and efficacious vaccines has been a major barrier for other infectious agents including fungi, partly due to of our lack of knowledge about the mechanisms that underpin protective immunity....
 

 Open Access DOI:10.23937/ijtd-2017/1710004

Prevalence of Urinary Schistosomiasis among Secondary School Students in Ifedore Local Government, Ondo State, Nigeria

Akinneye JO, Fasidi MM, Afolabi OJ and Adesina FP

Article Type: Research Article | First Published: August 04, 2 018

Schistosomiasis (Bilharziasis) is water borne parasitic disease caused by a blood fluke (trematode) of the genus Schistosoma. Adult schistosome worms live in mammalian host and the intermediate host is aquatic snail. Schistosomiasis ranks second to malaria in terms of prevalence and persistence with grave public health and socio-economic importance in endemic communities. This study assessed the prevalence of urinary schistosomiasis among students of five selected secondary schools in Ifedore Lo...
 

 Open Access DOI:10.23937/ijtd-2017/1710003

Chronic Skin Ulcer due to Mycobacterium Simiae in an Immunocompetent Lady

Lakshmi Vemu, Ashok R, Chaitanya Veena and G Satyanarayana

Article Type: Case Report | First Published: August 04, 2 018

Skin and soft tissue infections (SSTIs) with Nontuberculous Mycobacteria (NTMs) are increasingly encountered in recent times. We describe a case of a chronic non-healing ulcer on the foot of a young immunocompetent lady caused by Mycobacterium simiae. The diagnostic approach and successful management of the case have been reviewed. This is probably the first case report SSTI due to M. simiae from India....
 

 Open Access DOI:10.23937/ijtd-2017/1710002

Uncomplicated Malaria in Children under 6 Months or Less than 5 Kg; How Prescribers in Ghana Manage it in the Absence of a National Policy

Evans Paul Kwame Ameade, Cynthia Gbolo Tee, Henrietta Chefudeme Dakurah and Hamdaratu Mateko Opata

Article Type: Research Article | First Published: July 20, 2018

Malaria caused by various species of Plasmodium had brought untold socio-economic burden to poor and developing countries of the world. Most malaria associated deaths occur in children below 5 years. The suggestion that antibodies and toxic nature of fetal hemoglobin provide immunity against malaria in children less than 6 months had been disproven. With Ghana having no treatment guideline on the management of uncomplicated malaria in this age group, this study ascertained how Ghanaian prescribe...
 

 Open Access DOI:10.23937/ijtd-2017/1710001

Rubella Cases Detection through Measles Surveillance System from 2012 to 2016 in Côte d'Ivoire

Christophe Kouakou Nguessan, Serge Kouadio Agbo, Youssouf Traore, Cyrille Gourmanon, Daniel Kouadio Ekra and Simplice Ncho Dagnan

Article Type: Research Article | First Published: May 16, 2018

Rubella is a contagious disease caused by a virus. Rubella is a major cause of miscarriage or serious birth defects in a developing baby if a woman is infected while she is pregnant. Côte d'Ivoire is a country that is not immunizing against rubella in its Expend program on immunization (EPI)....

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ClinMed Journals Index Copernicus Values

Clinical Medical Image Library: 93.51

International Journal of Critical Care and Emergency Medicine: 92.83

International Journal of Sports and Exercise Medicine: 91.84

International Journal of Womens Health and Wellness: 91.79

Journal of Musculoskeletal Disorders and Treatment: 91.73

Journal of Geriatric Medicine and Gerontology: 91.55

Journal of Infectious Diseases and Epidemiology: 91.55

Clinical Medical Reviews and Case Reports: 91.40

International Archives of Nursing and Health Care: 90.87

International Journal of Ophthalmology and Clinical Research: 90.80

International Archives of Urology and Complications: 90.73

Journal of Clinical Nephrology and Renal Care: 90.33

Journal of Family Medicine and Disease Prevention: 89.99

Journal of Clinical Gastroenterology and Treatment: 89.54

Journal of Dermatology Research and Therapy: 89.34

International Journal of Clinical Cardiology: 89.24

International Journal of Radiology and Imaging Technology: 88.88

Obstetrics and Gynaecology Cases - Reviews: 88.42

International Journal of Blood Research and Disorders: 88.22

International Journal of Diabetes and Clinical Research: 87.97




New Issues

VOLUME 8, ISSUE 2

International Journal of Clinical Cardiology

ISSN: 2378-2951 | ICV: 89.24

VOLUME 8

VOLUME 8, ISSUE 2

Obstetrics and Gynaecology Cases - Reviews

ISSN: 2377-9004 | ICV: 88.42

VOLUME 8

VOLUME 7, ISSUE 1

Journal of Hypertension and Management

ISSN: 2474-3690 | ICV: 87.69

VOLUME 7

VOLUME 8, ISSUE 2

International Journal of Diabetes and Clinical Research

ISSN: 2377-3634 | ICV: 87.97

VOLUME 8

VOLUME 7, ISSUE 4

Journal of Infectious Diseases and Epidemiology

ISSN: 2474-3658 | ICV: 91.55

VOLUME 7