Journal of Clinical Nephrology and Renal Care is an international, open access, peer reviewed journal that publishes wide variety of clinical information in all the interdisciplinary aspects of Nephrology. The main objective of the journal is to set a forum for publication, education, and exchange of opinions, and to promote research and publications globally. The Journal provides a podium for all clinicians, surgeons and health professionals to contribute their findings and help raise awareness among community in various aspects of renal care. We aim to publish highest quality clinical content via open access platform providing the readers at no cost, immediate and unlimited access.

Journal of Clinical Nephrology and Renal Care is an open journal, accelerates research updates in various aspects such as discovery and innovation in Pediatric Nephrology, Basic Nephrology, Clinical Nephrology, Dialysis, Renal Anatomy, Physiology, Pathophysiology, functioning, Development and Histology, Glomerular/Tubulointerstitial Disease, Diuretic Pharmacology, Acute and Chronic Kidney Injury, Kidney Failure, Urinary Tract Infections, Tumors, Nephrolithiasis, etc. The journal accepts manuscript formats such as Original Article, Reviews, Mini Reviews, Short Communications, Case Reports, Clinical Image, Perspectives/Opinions, Letters, Short Note and Commentaries. All articles published in the journal are subject to a rigorous peer review process. It encourages authors to publish their work in detail to disseminate the updated research findings.

 
Journal Information

Title: Journal of Clinical Nephrology and Renal Care

ISSN: 2572-3286

Editor-in-chief: Saeid Mordechai Nosrati

NLM title abbreviation: J Clin Nephrol Ren Care

ISO abbreviation: J Clin Nephrol Ren Care

Other titles: JCNRC

Category: Nephrology/Renal

DOI: 10.23937/2572-3286

Peer review: Double blind

Review speed: 3 weeks

Fast-track review: 10 days

Publication format (s): Electronic and print

Publication policy: Open Access; COPE guide

Publication type(s): Periodicals

Publisher: ClinMed International Library

Country of publication: USA

Language: English

Contact email: contact@clinmedjournals.org

 
Articles Search by   Keyword   |   Journal title   |   Author name   |   DOI

 

 Open Access DOI:10.23937/2572-3286.1510039

Utility of Trend of Nephrocheck (IGFBP7 × TIMP-2) Biomarker for Early Identification of Acute Kidney Injury in Critically Ill Patients with Sepsis or Respiratory Failure

Ena Gupta, Ravi Sunderkrishnan, Nimrita Sidhu, Maria P Martinez Cantarin, Michael Baram and Bharat Awsare

Article Type: Original Research | First Published: August 27, 2018

Many studies have shown the association between acute kidney injury (AKI) and morbidity and mortality in the Intensive Care Unit (ICU). Traditional measures of AKI, such as serum creatinine and urine output, fail to show dynamic changes in renal function. A feasibility study was performed to evaluate the Nephrocheck test system which comprises of two biomarkers (Insulin-like growth factor binding protein 7 (IGFBP7) and tissue inhibitor of metalloproteinases-2 (TIMP-2)) to screen for patients at ...
 

 Open Access DOI:10.23937/2572-3286.1510038

Tolerability of Double Filtration Plasmapheresis (DFPP) in the Remission-Induction of Severe Lupus Nephritis

Shafira Mohamad Sha

Article Type: Review Article | First Published: July 04, 2018

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by a multitude of autoantibody production. Lupus nephritis (LN) is one of its most severe manifestations and its treatment is well established with the usage of immunosuppressions. However the use of these immunosuppressions at high doses are fraught with adverse effects including infections, subfertility and even malignancy....
 

 Open Access DOI:10.23937/2572-3286.1510037

Genetic Deletion of the Lipid Raft Protein Caveolin-1 Leads to Worsening Renal Fibrosis

S Chand, J Hazeldine, SW Smith and R Borrows

Article Type: Research Article | First Published: June 25, 2018

Renal disease is a major global public health issue. Renal interstitial fibrosis is the characteristic histopathological finding in all progressive renal disease. Caveolin-1 is the essential structural protein for lipid rafts called caveolae that are ubiquitously distributed among fibroblasts, endothelial and epithelial cells. Caveolin-1 acts as an intracellular signalling pathway chaperone in fibrotic disease....
 

 Open Access DOI:10.23937/2572-3286.1510036

Alport Syndrome: No Evidence of Improved Prognosis in Modern Era

Kelly YP, Wallis L, Patil A, Murray S, Kant S, Kaballo M5, Casserly L, Doyle B, Dorman T, O'Kelly P and Conlon PJ

Article Type: Research Article | First Published: June 09, 2018

Alport syndrome is an inherited renal disease, first described in 1927, which is characterized by haematuria, renal failure, hearing loss, lenticonus, retinal flecks, a lamellated glomerular basement membrane and mutations in the COL4A5 or COL4A3/COL4A4 genes leading to abnormal Type IV collagen composition. The prevalence of the disease is estimated at 1 in 50,000 live births....
 

 Open Access DOI:10.23937/2572-3286.1510035

Effects of Intra-Dialysis Resistance Training in Hemodynamic Parameters, Oxidative Stress and Health-Related Quality of Life in Patients with Chronic Kidney Disease

Bruna S Lourenco, Marcos A Nascimento, Vicente N Siqueira, Sergio A Draibe, Marco T Mello, Sergio Tufik, Maria EF Canziani and Elisa MS Higa

Article Type: Research Article | First Published: May 06, 2018

Chronic kidney disease is a public health problem that causes severe complications to the patient. The major damage is the loss of muscle mass, with a consequent reduction in the functional capacity that is associated with hypertension and increased oxidative stress. This study aimed to evaluate the effect of intra-dialysis resistance training on the hemodynamic parameters, oxidative stress and quality of life in patients with chronic kidney dise...
 

 Open Access DOI:10.23937/2572-3286.1510034

Effective Role of CVVH in Fatal Phenobarbital Overdose Clearance: A Case Report

Chaudhry Adeel Ebad, Alan Gaffney and Peter J Conlon

Article Type: Case Report | First Published: January 31, 2018

We report affective utilization of continuous veno-venous hemofiltration for removal of phenobarbital in a patient who took twice amount of fatal dose and was hemodynamically stable. Historically treatment includes supportive care, activated charcoal and urinary alkalinisation along with the application of extracorporeal treatments such as charcoal haem perfusion or hemodialysis and continuous veno-venous hemodiafiltration are affective treatment...
 

 Open Access DOI:10.23937/2572-3286.1510033

A Self-Sufficiency Philosophy for Non-Communicable Disease Control

Narisa Futrakul and Prasit Futrakul

Article Type: Communication | First Published: November 25, 2017

A non-communicable disease comprising various vascular diseases namely renal microvascular disease, cerebrovascular disease, and coronary vascular disease, has been a threatening public health problem today. The failure of preventive strategy is due to the lack of understanding the nature of the origin of vascular disease....
 

 Open Access DOI:10.23937/2572-3286.1510032

Frequency of Hyperkalemia in Chronıc Kidney Patients Under Regular Nephrology Care

Aysun Aybal Kutlugun, Canan Yildiz and Fatma Ayerden Ebinc

Article Type: Original Article | First Published: October 19, 2017

Hyperkalemia is an important life-threatening electrolyte disorder and one of the most important complications of Chronic Kidney Disease (CKD). Decreased Potassium (K) excretion due to decreased glomerular filtration rate and reduced tubular secretion due to tubulointerstitial dysfunction lead to abnormal K balance and hyperkalaemia in CKD....
 

 Open Access DOI:10.23937/2572-3286.1510031

Evaluation of the Change in Hemoglobin Values after the Administration of Intravenous Iron Therapy on Chronic Hemodialysis Patients with Anemia and Elevated Ferritin Levels

Grishma Desai, Ted Walton and John J Doran

Article Type: Research Article | First Published: September 28, 2017

Dialysis patients may experience anemia due to functional iron deficiency, which occurs in the presence of sufficient iron stores but not enough circulating iron to provide Erythropoiesis-Stimulating Agents (ESAs) the ability to increase hematopoiesis....
 

 Open Access DOI:10.23937/2572-3286.1510030

Sepsis and Renal Replacement Therapy

Sarinya Boongird, Supawadee Suppadungsuk, Sarassawan Kananuraks and Arkom Nongnuch

Article Type: Review Article | First Published: September 08, 2017

Sepsis has long been recognized as the most common cause of Acute Kidney Injury (AKI), present in approximately 11-40% of patients who are admitted to intensive care units....
 

 Open Access DOI:10.23937/2572-3286.1510029

Evaluation of Ultrasensitive C-Reactive Protein as a Cardiovascular Risk Marker in Pediatric Patients with End-Stage Renal Disease on Peritoneal Dialysis

Gustavo Orellana, Pedro Zambrano, Alejandro Sepúlveda, Ines Araneda, Jorge Rodriguez and Arnoldo Quezada

Article Type: Research Article | First Published: September 02, 2017

Patients with End-Stage Renal Disease (ESRD) on Peritoneal Dialysis (PD) experience high morbidity and mortality due to Cardiovascular (CV) disease. In pediatric patients, CV problems include Left Ventricular (LV) abnormalities, hypertension, and arrhythmias....
 

 Open Access DOI:10.23937/2572-3286.1510028

Anesthesia Considerations for Insertion of the Peritoneal Dialysis Catheter

Xihui Liu, Xiaoyan Zuo, Xueyuan Heng, Zita Abreu, Todd Penner, Lashmi Venkatraghavan and Joanne M Bargman

Article Type: Research Article | First Published: September 01, 2017

Laparoscopy is an effective method of implantation for Peritoneal Dialysis (PD) catheters. However, in many centers around the world, Peritoneal Dialysis Catheter (PDC) insertions are done using an open surgical method, associated with greater surgical trauma and longer duration of hospitalization....
 

 Open Access DOI:10.23937/2572-3286.1510027

Sporadic Isolated Fanconi Syndrome due to a Mutation of EHHADH: A Case Report

Eleanor G Seaby, David J Bunyan, Sarah Ennis and Rodney D Gilbert

Article Type: Case Report | First Published: August 31, 2017

Hereditary, isolated Fanconi syndrome has been described a handful of times in the literature, displaying variable Mendelian patterns of inheritance. Some cases segregate as autosomal dominant and may or may not be associated with renal failure, whilst other kindreds show recessive and X-linked recessive inheritance....
 

 Open Access DOI:10.23937/2572-3286.1510026

Effects of Two Types of Protein Supplementation in Patients on Peritoneal Dialysis

Fabiola Pansani Maniglia, Edileuza Santana Soares Penido, Naiane Cristina Soares and Sergio Arthur de Oliveira Campos

Article Type: Original Article | First Published: August 30, 2017

Chronic Kidney Disease (CKD) is characterized by the incontrovertible and gradual loss of endocrine, tubular, and glomerular kidney function, which impairs the removal of toxic metabolites from the body....
 

 Open Access DOI:10.23937/2572-3286.1510025

Anti-Glomerular Basement Membrane Disease: A Case Report of an Uncommon Entity with Atypical Histological Findings

Gerren Hobby, Mohammed Siddiqui, Shree Sharma and Manisha Singh

Article Type: Case Report | First Published: June 05, 2017

Anti-glomerular basement membrane disease is one of the infrequently encountered nephritic disorders, but one which can lead to poor renal and patient survival. Recent reports have noted the occurrence of anti-GBM disease with atypical histological features on kidney biopsy....
 

 Open Access DOI:10.23937/2572-3286.1510024

Anti-Neutrophil Cytoplasmic Antibody (Anca)-Negative Small Vessel Pulmonary Vasculitis in a Chronic Hemodialysis Patient

Jose Luis Merino, Yésika Amézquita, Maria Ovidia López-Oliva, María Concepción Prados, Pilar Fidalgo and Vicente Paraíso

Article Type: Case Report | First Published: April 17, 2017

The development of vasculitis in renal replacement therapy is rare due to the immunological condition of these patients. Its diagnosis is often complex and invasive tests are usually required. A multidisciplinary approach is mandatory and a broad study (including lung biopsy) is necessary for its diagnosis which is crucial to support the necessity of immunosuppressive therapy in this kind of patients. ...
 

 Open Access DOI:10.23937/2572-3286.1510023

Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) or Stevens-Johnson Syndrome (SJS): Does the Name Matter!

Awad Magbri and Harshit Seth

Article Type: Case Report | First Published: April 13, 2017

The case is of 23-year-old Caucasian male who fell from 30 feet height in a suicidal attempt. He presented to the hospital with fever, generalized macula-papular rash, and malaise. He was discharged initially to LTAC for continued recovery. After 3 weeks in the LTAC he developed pinhole infection of his hip that was reported methicillin resistant staphylococcal infection (MRSA) positive and was started on Vancomycin....
 

 Open Access DOI:10.23937/2572-3286.1510022

Magnetic Resonance Urography as an Imaging Modality for Urinary Stone Diseases

Donghua Xie, Guy M Nehrenz, Fernando Bianco, Boris Klopukh and Edward Gheiler

Article Type: Review Article | First Published: February 28, 2017

Magnetic resonance urography (MRU) techniques have matured and have become applicable to the diagnosis of more and more diseases in urinary tract. Modern MRU offers not only increased spatial and temporal resolution, but also provides anatomic and functional information on renal perfusion, excretion and drainage. Patients with renal colic are better examined by non-enhanced computed tomography (CT) scanning because it is highly sensitive in detec...
 

 Open Access DOI:10.23937/2572-3286.1510021

The Effect of Chronic Kidney Disease on a Physical Activity Intervention: Impact on Physical Function, Adherence, and Safety

CK Liu, F-C Hsu, V Yank, T Church, S Kashaf, S Nayfield, A Newman, DE Weiner, RS Stafford, B Nicklas3, J Milton, KM Beavers, JD Shegog, RA Fielding and LIFE-P Research Group

Article Type: Research Article | First Published: February 14, 2017

Because chronic kidney disease (CKD) is associated with muscle wasting, older adults with CKD are likely to have physical function deficits. Physical activity can improve these deficits, but whether CKD attenuates the benefits is unknown. Our objective was to determine if CKD modified the effect of a physical activity intervention in older adults....
 

 Open Access DOI:10.23937/2572-3286.1510020

Conventional High Volume Hemofiltration for Hypertriglyceridemic Pancreatitis

Juan F Martin-Lazaro, Sanja Janjanin, Vasu Kulhalli and James Napier

Article Type: Review Article | First Published: February 04, 2017

Several therapies have been proposed for the treatment of Hypertriglyceridaemic Pancreatitis; an uncommon cause (1-4%) of acute pancreatitis in which physio-pathology is unclear. Different combinations of medical drugs have been used to reduce hypertriglyceridaemia. Plasmapheresis is an invasive but effective alternative for severe cases but it is an expensive and not very accessible option in most of the centres....
 

 Open Access DOI:10.23937/2572-3286.1510019

Interventional and Surgical Treatments for Renal Artery Aneurysms

Donghua Xie, Edward Gheiler and Xiangfei He

Article Type: Review Article | First Published: February 03, 2017

Renal artery aneurysm (RAA) is an infrequent entity. Most of them are asymptomatic, but when they present as a rupture a high mortality is associated. Due to the potential risks of rupture and renal dysfunction and some persistent symptoms like hypertension, RAAs must be treated if feasible. Coil embolization or covered stent placement can now be used to treat patients with aneurysms whose size or location would make a surgical approach problemat...
 

 Open Access DOI:10.23937/2572-3286.1510018

Henoch-Schonlein Purpura after Tetanus Toxoid Vaccination: A Case Report

Wei-Yen Kong, Wan Zaharatul Ashikin Wan Abdullah, Halim Gafor, Rozita Mohd and Rizna Abdul Cader

Article Type: Case Report | First Published: December 21, 2016

We present here the first reported case of a young boy who developed classic features of HSP, i.e. palpable purpura, arthralgia, abdominal pain with bloody diarrhea and kidney involvement, following a tetanus vaccine. The diagnosis of HSP was confirmed by skin biopsy and also biopsies obtained from esophagogastroduodenoscopy and colonoscopy. He was initially treated with pulsed intravenous methylprednisolone....
 

 Open Access DOI:10.23937/2572-3286.1510017

Catheter-Related Bacteraemia in Renal Replacement Therapy in Critically Ill Patients: Can We Use Femoral Access?

Sergio Castano-Avila, Javier Maynar-Moliner, Yolanda Poveda-Hernandez, Fernando Fonseca-San Miguel, Alejandro Martin-Lopez, Carlos Perez-Lejonagoitia, Noemi Legaristi-Florez, Ana Aced-Urbano, Elena Uson-Garcia and Alberto Manzano-Ramirez

Article Type: Original Article | First Published: December 14, 2016

Prospective analysis was conducted in critically ill patients with haemodialysis catheters between 25 October 2009 and 7 December 2010. We gathered data on: demographic characteristics, risk factors, extracorporeal therapy, mortality and microbiological results. CRB was detected through quantitative blood and catheter cultures. We assessed differences between aseptic and non-aseptic catheter insertion (p < 0.05)....
 

 Open Access DOI:10.23937/2572-3286.1510016

Surveillance of Hemodialysis Vascular Access with Temperature Biosensor Combined with Doppler-Ultrasound to Prevent Vascular Failure

Milagros Fernandez-Lucas, Fernando Caravaca-Fontan, Antonio Chinchilla, Jose-Luis Teruel, Nuria Rodriguez-Mendiola, Estefania Yerovi, Laura Blanco, Maria Delgado and Fernando Liano

Article Type: Research Article | First Published: December 12, 2016

Regular surveillance and pre-emptive correction of subclinical stenosis have been shown to be useful procedures for reducing the rate of vascular access (VA) failure. Blood flow (Qa) measurement is considered the best procedure for VA surveillance. Qa below 500 ml/min or reductions over 25% from preceding Qa measurements are predictors of VA thrombosis....
 

 Open Access DOI:10.23937/2572-3286.1510015

Prevalence of Echocardiographic Abnormalities and its Relation to Thyroid Abnormalities among Hemodialysis Patients

Osama A Khamis, Salama S Abdellatif, Mostafa A Alsawasany, Abdellah H ELSadek, Amin M Hegazy, Khaled M Dessouky and Ahmed M Fahmy

Article Type: Original Article | First Published: October 19, 2016

The kidney is involved in the regulation of thyroid hormones metabolism. Numerous abnormalities of thyroid hormones in end-stage kidney disease (ESKD) have been described. The aim of our study was to estimate the prevalence of thyroid dysfunction and its relation to Echocardiologic abnormalities in patients with end stage kidney disease....
 

 Open Access DOI:10.23937/2572-3286.1510014

Nephrologist Personality Traits and Optimal Renal Replacement Therapy Modality Initiation - 'Teamwork Makes the Dream Work'

Agnes Masengu, Melanie Wolfenden, Alexander P Maxwell and Jennifer B Hanko

Article Type: Research Article | First Published: October 12, 2016

Personality traits have been associated with job performance. Previous studies have explored nephrologist preferences regarding optimal renal replacement therapy (RRT) outcomes in patients with end-stage renal disease. The role of physician personality traits and patient outcomes has not been investigated. A pilot study was carried out at a single centre to investigate this....
 

 Open Access DOI:10.23937/2572-3286.1510013

Evaluation of the Change in Serum Potassium Levels after Potassium Administration

Houda Aboujamous, Ted Walton and John J Doran

Article Type: Research Article | First Published: September 15, 2016

The objective of this study was to quantify the change in serum potassium level after intravenous or oral potassium administration. Secondary objectives include investigating the possible influence of concurrent medications, renal function, and Body Mass Index (BMI)....
 

 Open Access DOI:10.23937/2572-3286.1510012

Does Pre-Eclampsia Predispose Patients to the Development of Focal Segmental Glomerulosclerosis? 'The Chicken or the Egg?'

Nicole Lioufas, Jonathan Ling, Juli Jaw, Mathew Mathew, Matthew Jose and Richard Yu

Article Type: Case Series | First Published: August 31, 2016

Pre-eclampsia is the most common medical complication of pregnancy affecting 3-5% of pregnancies worldwide. Traditional teaching has generally maintained that the natural history of Pre-eclampsia is one of resolution of renal pathology and other clinical features- some days to weeks after delivery of the placenta. Renal injury is mediated by both endothelial and podocyte injury in pre-eclampsia. In some women however, the renal injury does not re...
 

 Open Access DOI:10.23937/2572-3286.1510011

Reducing Non-Beneficial Renal Replacement Therapy in the ICU: Teaching Fellows to Negotiate a Time-Limited Trial

Paul J Hutchison, Yusra Cheema, Hala Yamout, Kathy Johnson Neely and Cybele Ghossein

Article Type: Research Article | First Published: June 27, 2016

Background:Acute kidney injury (AKI) carries a high mortality among patients treated in the intensive care unit (ICU). Continuous renal replacement therapy (CRRT) is used to treat complications of AKI, but it is often initiated in patients who have little hope of surviving. Objective:The authors sought to teach nephrology and pulmonary fellows how to utilize a time-limited trial strategy when discussing CRRT. ...
 

 Open Access DOI:10.23937/2572-3286.1510010

Outcomes Associated with a Heparin-Free Hemodialysis Protocol and Review of the Literature

Elizabeth Liang, Mayra Rodriguez, Melissa Mueller, Matthew K Abramowitz and Michele H Mokrzycki

Article Type: Review Article | First Published: May 20, 2016

Background: We aimed to determine outcomes associated with a heparin-free hemodialysis (H-HD) protocol in hospitalized patients. Methods: A retrospective study comparing 2 intra-dialytic heparin protocols: H + HD (routine heparin prime/bolus dosing) and H-HD (saline prime, heparin avoidance). HD circuit patency, need for intra-dialytic interventions and patient bleeding events were the outcomes....
 

 Open Access DOI:10.23937/2572-3286.1510009

Guillain-Barre Syndrome Associated with Cyclosporine A

Rizawati RI, Shamila K, Shafira MS and Ruslinda M

Article Type: Case Report | First Published: May 20, 2016

Guillain-Barre syndrome (GBS) is also known as an acute inflammatory demyelinating polyneuropathy (AIDP). It is an immune-mediated polyneuropathy commonly post-infectious in origin that presents with ascending weakness, loss of sensation and deep tendon reflexes resulting from demyelination of peripheral nerve. Drug-induced neuropathy has been describing before and remains a rare clinical entity. Development GBS after an episode of infections suc...
 

 Open Access DOI:10.23937/2572-3286.1510008

A Review on the Potential Role of Vitamin D and Mineral Metabolism on Chronic Fatigue Illnesses

Anna Dorothea Hock

Article Type: Review Article | First Published: May 14, 2016

Vitamin D3-insufficiency/ deficiency is a common condition arising from prevalent indoor activities and use of sunscreens with high protection factor. Lacking sunlight is frequent in patients suffering from chronic fatigue syndrome (CFS), fibromyalgia (FMS), and myalgic encephalopathy (ME) probably because of fatigue-related reduction of outdoor activity, high premorbid engagement in professional or caring activities, and preceding stressful life...
 

 Open Access DOI:10.23937/2572-3286.1510007

Depression in Late-Life patients with End-Stage Renal Disease under Online-Haemodiafiltration is Associated with Low Social Support, Muscular Mass and Creatinine Serum Levels

Leonilde Amado, Veronica Poveda, Ricardo Ferreira, Nuno Ferreira, Vasco Miranda Laetitia Teixeira, Constanca Paul, Alice Santos-Silva and Elisio Costa

Article Type: Original Article | First Published: April 28, 2016

Patients with end-stage renal disease (ESRD) under dialysis showed a higher prevalence of depression, which is independently associated with non-adherence, hospitalization and mortality. We aimed to evaluate the prevalence of depression and associated variables, among ESRD late-life patients under online-haemodiafiltration (OL-HDF)....
 

 Open Access DOI:10.23937/2572-3286.1510006

A Study Evaluating the Prevalence of Nephropathy among Type 2 Diabetes Patients Attending a Teaching Hospital in Malaysia

Salwa Selim Ibrahim Abougalambou, Syed Azhar Syed Sulaiman, Ayman S. Abougalambou and Mohamed Azmi Hassali

Article Type: Research Article | First Published: March 23, 2016

Nephropathy is a major cause of illness and death of patients with type 2 diabetes mellitus (DM), Diabetic nephropathy has become the leading cause of end-stage renal disease; kidney failure that requires a lifetime of dialysis. It develops in about 20-40% of Type 2 Diabetes patients....
 

 Open Access DOI:10.23937/2572-3286.1510005

Patient Perception of Treatment Success: A Qualitative Interview Study in Patients with End-stage Renal Disease undergoing Hemodialysis

Anna Ryden, Matthew Wolfe and Mona L Martin

Article Type: Research Article | First Published: February 01, 2016

End-stage renal disease treated with hemodialysis (ESRD-HD) is associated with poor outcomes for patients and can substantially reduce health-related quality of life (HRQL). Alongside drug development for this patient group, there is a need for a better understanding of patients' perceptions of their condition, their symptoms and the impact ESRD-HD has on their lives. Here, we report data from qualitative, semi-structured, concept-elicitation int...
 

 Open Access DOI:10.23937/2572-3286.1510004

HLA-B*60 and HLA-DR*14 Alleles might be associated with the Hyperuricemic and Possibly Metabolic Syndrome Status in Renal Transplant

Gabriela Hernandez-Molina, Joaquin Zuniga, Adriana Torres-Machorro, Lourdes Mena-Hernandez, Antonio Cachafeiro, Julio Granados and Marina Rull-Gabayet

Article Type: Research Article | First Published: January 31, 2016

Background: Hyperuricemia is frequent among renal transplant recipients. The role of the HLA system in the susceptibility of hyperuricemia is unknown. Methods: We evaluated the HLA-B and HLA-DRB1 distribution among 160 renal recipients: 132 with hyperuricemia (Group 1) and 28 free of it (Group 2) as well as 381 ethnic-specific Mexican-mestizo population historic controls. The HLA alleles were assessed by PCR-SSP and the HLA allele gene frequencie...
 

 Open Access DOI:10.23937/2572-3286.1510003

Assessing Renal Function in Adult Myelomeningocele Patients: Correlation between Volumetric- and Creatinine-based Measurements

Vij Sarah C, Karim Wadih, Luzny Patrik, Myers Jeremy B, Emilio Poggio, Herts Brian and Wood Hadley

Article Type: Research Article | First Published: January 31, 2016

Renal volume-based estimates of glomerular filtration rate (GFR) using computed tomography (CT) in renal donor populations have been described. We hypothesized that the same technology would be especially useful in myelomeningocele (MMC) patients for whom standard methods of GFR assessment are inaccurate....
 

 Open Access DOI:10.23937/2572-3286.1510002

Acute Kidney Injury in Patients with Pandemic 2009 H1N1 Influenza A on Extracorporeal Membrane Oxygenation: Case Series and Review of the Literature

Ibrahim A Qaqish and Mira T Keddis

Article Type: Review Article | First Published: August 22, 2015

The H1N1 influenza A (swine flu) was first recognized in 1918 during the influenza pandemic and was first isolated from humans in 1974. Several reports ofH1N1 influenza A was reported between 1958 and 2005 with mortality rates up to 17%. In 2009 worldwide outbreak of H1N1 influenza A led the world health organization to raise its pandemic alert to its highest level. H1N1 influenza A was found to be associated with significantly higher mortality i...
 

 Open Access DOI:10.23937/2572-3286.1510001

Eighteen-Months May be a Reliable Storage Period for Direct Immunofluorescent Slides of Renal Biopsies at Room Temperature

Tripti Kumar, Thomas Fennell and Ping L. Zhang

Article Type: Original Article | First Published: August 17, 2015

After the initial diagnosis of a renal biopsy, direct immunoflorescent (DIF) slides would be ideally kept for later internal and external reviews. Although there is an assumption that rapid reduction in florescent intensity occurs after DIF staining, no renal DIF study has addressed how long DIF slides can be reliably stored for re-examination at room temperature....

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Pubmed ID:25639474 | PMC ID:PMC4308811
Corpora Amylacea in Neurodegenerative Diseases: Cause or Effect?..
Pubmed ID:26550607 | PMC ID:PMC4634668
Differences in ME and CFS Symptomology in Patients with Normal and..
Pubmed ID:28713856 | PMC ID:PMC5510614
Gene-Specific Promoter Methylation Status in Hormone-Receptor-Positive..
Pubmed ID:26005715 | PMC ID:PMC4440485
A Derivative of Differentiation-Inducing Factor-3 Inhibits PAK1..
Pubmed ID:26688830 | PMC ID:PMC4682050
Overcoming Endocrine Resistance in Hormone-Receptor Positive Advanced..
Pubmed ID:26726315 | PMC ID:PMC4697745
Zinc Ionophore (Clioquinol) Inhibition of Human ZIP1-Deficient Prostate..
Pubmed ID:26878064 | PMC ID:PMC4751054
Electron Microscopic Analysis of Silicate and Calcium Particles..
Pubmed ID:27158665 | PMC ID:PMC4858188
Effects of chest physical therapy in patients with non-tuberculous mycobacteria
Pubmed ID:28804763 | PMC ID:PMC5552049
A Community-Based Exercise and Support Group Program Improves Quality..
Pubmed ID:26640827 | PMC ID:PMC4667740
Four Weeks of Balance Training Does Not Affect Ankle Joint Stiffness in Subjects..
Pubmed ID:27642647 | PMC ID:PMC5025258
Social Ecology and Diabetes Self-Management among Pacific Islanders..
Pubmed ID:28736764 | PMC ID:PMC4516390
Examining Characteristics of Hospitalizations in Heart Failure Patients: Results..
Pubmed ID:28736765 | PMC ID:PMC5517048