Journal of Musculoskeletal Disorders and Treatment is an international, open access, peer reviewed journal that publishes wide variety of information on conditions that affect the muscles, bones, and joints. The journal sets a forum for publication, education, and exchange of opinions globally. JMDT provides a podium for authors to contribute their findings and help raise awareness among readers on causes, diagnosis and prevention of various musculoskeletal disorders. We provide an immediate and unlimited access to highest quality clinical content via open access platform.

Journal of Musculoskeletal Disorders and Treatment focus on various aspects of Repetitive Motion Injuries, Repetitive Strain Injuries, Cumulative Trauma Disorders, Occupational Cervicobrachial Disorders, Overuse Syndrome, Regional Musculoskeletal Disorders, Soft Tissue Disorders, Work-Related Musculoskeletal Disorders, Musculoskeletal Disorders in the Elderly, Arthritis, Drug Interaction Checker, Fibromyalgia, Living Healthy, Lupus Osteoarthritis, Pill Identifier, Rheumatoid Arthritis, Sports Injuries, etc. Original Article, Reviews, Mini Reviews, Short Communications, Case Reports, Clinical Image, Perspectives/Opinions, Letters, Short Note and Commentaries are acceptable for publication. All articles published in the journal are subject to a rigorous peer review process.

Journal Information

Title: Journal of Musculoskeletal Disorders and Treatment

ISSN: 2572-3243

NLM title abbreviation: J Musculoskelet Disord Treat

ISO abbreviation: J Musculoskelet Disord Treat

Other titles: JMDT

Category: Musculoskeletal Disorders

DOI: 10.23937/2572-3243

Peer review: Double blind

Review speed: 3 weeks

Fast-track review: 10 days

Publication format (s): Electronic and print

Publication policy: Open Access; COPE guide

Publication type(s): Periodicals

Publisher: ClinMed International Library

Country of publication: USA

Language: English

Contact email:

Articles Search by   Keyword   |   Journal title   |   Author name   |   DOI


 Open Access DOI:10.23937/2572-3243.1510067

Wartime Orthopedic Surgical Judgment

Ismet Gavrankapetanovic and Adnan Papovic

Article Type: Short Note | First Published: May 29, 2019

Orthopedic surgical judgment and a decision-making process in peace is a topic that has been discussed and written about for decades, but the wartime surgical judgment is something that cannot be predicted or prepared for. There is no wartime surgery class in any medical school worldwide that can prepare a surgeon for his/her work under a wartime environment applying all of their knowledge, skill and effort to achieve the best possible result for a patient. With this short note, authors would li...

 Open Access DOI:10.23937/2572-3243.1510066

Total Talar Extrusion with Medial Malleolar Fracture

Rajesh MB, Chamma R and Ranganathan A

Article Type: Case Report | First Published: March 30, 2019

Total extrusion of the talus with disruption of all the ligaments is called "missing talus". It is a rare injury, associated with severe soft tissue damage and/or fracture. It is a tri-articular dislocation involving talotibial dislocation from above, subtalar joint below and talonavicular joint anteriorly. We present a report of a patient treated with immediate reimplantation and K-wire stabilisation leading to a successful outcome. A 57-year-ol...

 Open Access DOI:10.23937/2572-3243.1510065

Differences in Clinical Variables and Physical Activity Levels of Patients with Knee Osteoarthritis in Ibadan, Nigeria

Adesola C Odole, Ezinne C Ekediegwu and Mercy U Issa

Article Type: Original Article | First Published: March 20, 2019

Osteoarthritis (OA) is a major cause of disability worldwide and it often results in pain, decreased physical functioning and physical activity level. This study was aimed to investigate the Pain Intensity (PI), Physical Function (PF) and Physical Activity Level (PAL) of patients with knee OA and the difference in their PI and PF across the different physical activity levels (PALs). Participants who were more active reported lower PI and higher PF. No significant difference was found between PI ...

 Open Access DOI:10.23937/2572-3243.1510064

Effectiveness of Three Treatment Strategies on Quality of Life for Patients with Chronic Low Back Pain: A Multidisciplinary Approach as Key to Success

Eloy Ovando-Sanders, Lilia Patricia Bustamante-Montes, David Gustavo Rodriguez-Cisneros and Rafael Gonzalez-Alvarez

Article Type: Research Article | First Published: February 27, 2019

Low back pain (LBP) is one of the highest prevalence problems of public health. LBP affects up to 85% people worldwide. Somebody will be affected at less in one point of his life. LBP represent an enormous economic burden on society; its total cost includes: Direct medical costs, work absenteeism, insurance, lost production and disability benefits. Current treatments range from bed rest, physiotherapy, oral analgesic, muscle relaxants, injection of corticosteroids, local anesthetic, surgery, cel...

 Open Access DOI:10.23937/2572-3243.1510063

Prevalence, Perception and Risk Factors for Musculoskeletal Discomfort among Pregnant Women in Southeast Nigeria

Adinma JIB, Adinma ED, Umeononihu OS, Oguaka V, Adinma-Obiajulu ND and Oyedum SO

Article Type: Original Article | First Published: December 31, 2018

A lot of physical and hormonal changes that occur in pregnancy impact the musculoskeletal system leading to a variety of problems, such as back pain, pelvic/pubic pain, transient osteoporosis and tendonitis. The weight gain, hormonal and other biochemical changes that occur during pregnancy increase the strain on the vertebrae and the appendages resulting in increased laxity (and hence mobility) of joints, increased lumbar lordosis, stretching/weakness and separation of the anterior abdominal mu...

 Open Access DOI:10.23937/2572-3243.1510062

Decreased Self Report Physical Activity One Year after an Acute Ankle Sprain

Tricia Hubbard-Turner, Michael J Turner, Chris Burcal, Kyeongtak Song and Erik A Wikstrom

Article Type: Research Article | First Published: December 14, 2018

One of the biggest public health issues present today is physical inactivity. Physical inactivity is currently classified as one of the three highest risk behaviors in the development of cardiovascular disease, cancer, and other chronic diseases such as diabetes and obesity. Research consistently demonstrates the numerous physiological health and psychological well-being benefits with regular physical activity. Lee, et al. estimated globally 5.3...

 Open Access DOI:10.23937/2572-3243.1510061

Reversed Shoulder Arthroplasty on Chronic Glenohumeral Dislocations: A Small Retrospective Cases Series

Miguel Frias, Henrique Sousa, Tiago Pinheiro Torres and Pedro Lourenco

Article Type: Case Series | First Published: November 24, 2018

Anterior dislocation of the shoulder may go undiagnosed and may thus left untreated for a variable length of time. Chronic locked anterior dislocations of the glenohumeral joint is a rare condition. Its diagnosis and management can be challenging. Reverse shoulder arthroplasty has yelded satisfactory outcomes in patients with cuff tear arthropaty and other degenerative changes of the shoulder joint. The concept of this implant theoretically allow...

 Open Access DOI:10.23937/2572-3243.1510060

Physiotherapy Management of Chronic Low Back Pain Patients with Yellow Flags: A Systematic Review

Kieran Macphail

Article Type: Systematic Review | First Published: November 19, 2018

CLBP is the leading cause of years lived with disability worldwide and patients with yellow flags have the worst outcomes and contribute significantly to the societal cost. Clinicians are aware of the importance of yellow flags but feel undertrained to deal with them. Furthermore there is a lack of clarity for clinicians looking at how to specifically manage these patients from guidelines and an incredibly varied set of approaches available to clinicians. The objective of this review was to revi...

 Open Access DOI:10.23937/2572-3243.1510059

Biologics for Osteoporosis: Where Do We Stand?

Tamer A Gheita and Hanan M Fathi

Article Type: Editorial | First Published: November 12, 2018

Osteoporosis is a common disease with wide prevalence, especially in seniors. Fractures induced by osteoporosis not only decrease the patient's quality of life, but also cause heavy financial burden to the society during medical treatment making this major metabolic bone disease a growing health-economic problem worldwide. Estimated annual costs for osteoporotic fractures are between $10 billion and $17 billion in the United States with a provisional estimation by year 2025 to rise up to $25.3. ...

 Open Access DOI:10.23937/2572-3243.1510058

Hip Alpha Angle in Asymptomatic Population

Roberto Seijas, Pedro Alvarez, Oscar Ares, Andrea Sallent, David Barastegui and Ramon Cugat

Article Type: Original Article | First Published: November 05, 2018

Hip osteoarthritis is related to the deformity caused by femoroacetabular impingement (FAI). This lesion is related too with an increased performance of sports activities, such as soccer. Alpha angle is a possible measurement of the deformity caused by FAI, especially Cam-type lesion. The purpose of the present study is to describe the alpha angle measured in AP and axial projections in a group of soccer players, being able to compare it with the general population and populations of adult socce...

 Open Access DOI:10.23937/2572-3243.1510057

Hip Arthroscopy: A Narrative Review of the Current Literature

JRT Pietrzak, MJ Donaldson, B Kayani, FE Rowan and FS Haddad

Article Type: Review Article | First Published: August 18, 2018

The incidence of hip arthroscopy is increasing worldwide. This is due to improved knowledge of the surgical anatomy, expansion of surgical indications, evolution and refinement of surgical instrumentation and continued reports of good long-term functional results. However hip arthroscopy remains a technically challenging surgical procedure with a described "steep" learning curve....

 Open Access DOI:10.23937/2572-3243.1510056

Inferior Dislocation of the Shoulder Complicated with Brachial Plexus Palsy: A Case Report

Hamdi Kaziz, Mohamed Amine Triki, Sofien Benzarti, Thabet Mouelhi, Nader Naouar and Mohamed Laziz Ben Ayeche

Article Type: Case Report | First Published: August 08, 2018

Luxatio erecta humeri are an extremely uncommon injury of the shoulder. The reported mechanism is usually a hyper-abduction of the arm, so that the humeral neck is livered against the acromion causing inferior displacement of the humeral head through the capsule tears. Similar to all shoulder injuries, several complications may occur in shoulder erecta dislocation. There are few reports regarding associated injuries to this entity....

 Open Access DOI:10.23937/2572-3243.1510055

Ultrasonography as an Evaluation Tool in a Randomized Controlled Trial Assessing Balneotherapy Effects in Rheumatoid Arthritis

Santos Isabel, Vasconcelos Jose Carlos, Ribeiro Claudia, Moreira Carolina, Magalhães Alexandre, Cantista Pedro and Vasconcelos Carlos

Article Type: Original Article | First Published: August 06, 2018

A prospective controlled clinical trial, not blinded, randomly assigned of patients with rheumatoid arthritis accordingly to the American College of Rheumatology criteria. The Balneotherapy group received Balneotherapy's throughout 21 days in S. Jorge Spa. The main outcome was hand/wrist ultrasonography measured at the same moments in the two groups, and McNemar's tests were used to compare changes in ecographics signals, with a 5% statistical si...

 Open Access DOI:10.23937/2572-3243.1510054

Knee Compression Loading When Lying Supine: Effects of Foot Position on Mattress

Buckley JG, Nichols S and Bhattacharjee C

Article Type: Original Research | First Published: June 16, 2018

Knee loading from standing for long periods has been shown to cause degenerative effects in knee cartilage, and this has been linked to the onset and progression of osteoarthritis. When lying supine because the heel protrudes 'outwards' from the back of the leg, contact forces are concentrated at the heel and act to 'push' the knee into full extension. The resulting knee-moment (compression loading) can be experienced for prolonged periods....

 Open Access DOI:10.23937/2572-3243.1510053

Clinical Course and Sustained Remission in Rheumatoid Arthritis

Mariana Lagrutta, Roberto Leandro Parodi and Alcides Alejandro Greca

Article Type: Short Review | First Published: July 05, 2018

Rheumatoid arthritis (RA) is an inflammatory, multisystemic autoimmune disease. It has been described as an often progressive chronic disease, characterized by severe functional decline, radiographic progression, frequent work disability and premature mortality. Efforts have been made to identify among patients with peripheral inflammatory arthritis which patients will have a benign course, with spontaneous resolution, and which will develop a chronic progressive inflammatory disabling disease i...

 Open Access DOI:10.23937/2572-3243.1510052

Performance of Hi-Flex Femoral Component in Total Knee Arthroplasty - A Randomized Control Study

Sheldon Moniz, Ryan Du Sart and Piers Yates

Article Type: Research Article | First Published: June 16, 2018

Total knee replacement (TKR) is a surgical procedure for intractable degenerative disease of the knee joint. Despite continued evolution in prosthesis design and surgical procedures, restricted range of motion and functional performance is still common in patients undergoing TKR. Posterior stabilized TKR aims to maintain a more reproducible roll back than cruciate retaining and mobile bearing knees, possibly leading to better flexion and function....

 Open Access DOI:10.23937/2572-3243.1510051

The Effects of Scapular Mobilisation on Upper Limb Neurodynamic Test 1: A Randomised, Placebo-Controlled Crossover Study

Koya Mine

Article Type: Original Research | First Published: May 26, 2018

Cervical and/or upper limb pain due to peripheral neuropathy is a common clinical condition in general population. Although the exact prevalence or incidence is uncertain, cervical radiculopathy is estimated to have a yearly incidence of 0.8-3.5 cases per 1,000 people, with a peak at 50 to 54 years of age in the US....

 Open Access DOI:10.23937/2572-3243.1510050

Carpometacarpal Boss with Extensor Tendon Rupture: Case Report

Ayesha Yahya and H Brent Bamberger

Article Type: Case Report | First Published: May 25, 2018

Carpometacarpal boss is a rare cause of pain and swelling on the dorsum of the hand. Literature is limited on the etiology of this condition and there is no consensus on treatment. We report an unusual case of a 53-year-old man with extensor tendon rupture caused by carpometacarpal boss. Surgical excision of the bony growth and repair of the EIP utilizing interpositional tendon autograft resulted in relief of symptoms and return of function....

 Open Access DOI:10.23937/2572-3243.1510049

Oral Ibuprofen Interferes with Cellular Healing Responses in a Murine Model of Achilles Tendinopathy

Adam Bittermann, Shuguang Gao, Sabah Rezvani, Jun Li, Katie J Sikes, John Sandy, Vincent Wang, Simon Lee, John Holmes, Johnny Lin and Anna Plaas

Article Type: Original Research | First Published: May 21, 2018

The attempted healing of tendon after acute injury (overloading, partial tear or complete rupture) proceeds via the normal wound healing cascade involving hemostasis, inflammation, matrix synthesis and matrix remodeling. Depending on the degree of trauma and the nature of the post-injury milieu, a variable degree of healing and recovery of function occurs....

 Open Access DOI:10.23937/2572-3243.1510048

Bisphosphonates and MeCP2 Deficiency: Cellular Studies and Clinical Application in Rett Syndrome

Jay R Shapiro and Mary E Blue

Article Type: Short Note | First Published: May 18, 2018

In this Short Note, we assess what is known about the structural deficits in bone in Rett syndrome (RTT), a rare x-linked neurodevelopmental disorder and in mouse models of RTT and provide a rationale for the treatment of bone fragility observed in this disorder. RTT is caused by mutations in a gene that encodes for methyl CpG protein binding protein 2 (MeCP2), which can act as an inhibitor or activator of gene transcription. MeCP2 is ubiquitously expressed throughout the body....

 Open Access DOI:10.23937/2572-3243.1510047

Preoperative Factors Predicting Failure of Hemiarthroplasty after Displaced Subcapital Fractured Neck of Femur in the Active Elderly

Moniz S, Eranki A, Hodgkinson S and Yates P

Article Type: Research Article | First Published: May 14, 2018

Displaced intracapsular hip fractures are a common problem in Australia. The majority of patients with this injury are of low demand. They present with fragility fractures and are treated successfully with a hemiarthroplasty which offers a shorter operative time, less chance of reoperation and less blood loss. In more active individual's acetabular erosion, pain and decreased function limit the success of these implants and a total hip replacement may be beneficial....

 Open Access DOI:10.23937/2572-3243.1510046

Effect of Postural Correction and Orthopedic Massage Therapy on the Frequency of Headaches and Tenderness of Muscles in Migraine Patients

Doris Vahtrik, Margot Bergmann , Ingrid Vanahunt and Mark Braschinsky

Article Type: Original Research | First Published: May 12, 2018

Due to controversial information about the effect of different physiotherapy methods used in the treatment of migraine patients, the aim of the study was to assess the effectiveness of postural correction and orthopedic massage as interventions against headache, and neck and shoulder area muscles tenderness, on improving active range of cervical motion and upper body posture in episodic migraine patients (n = 10) before, after five-week therapy p...

 Open Access DOI:10.23937/2572-3243.1510045

Diagnostic Ultrasound for Traumatic Radial Nerve Injury: A Visual Vignette

Rana Terlemez, Selda Çiftçi, Tülay Erçalık, Jülide Öncü, Figen Yilmaz and Banu Kuran

Article Type: Short Commentary | First Published: March 31, 2018

A 35-year-old man had fallen down from the first floor and admitted emergency department with pain, swelling and deformity on the right elbow. The radiograph showed fracture of the right supracondylar humerus. After surgical exploration and internal fixations, the patient referred to our clinic as elbow contracture with traumatic median and ulnar nerve injury....

 Open Access DOI:10.23937/2572-3243.1510044

Tocilizumab in Paget's Disease of Bone and Rheumatoid Arthritis: A Case Report

Giovanna Cuomo, Ciro Romano, Elisabetta Maria Frongillo, Gaetano Scognamiglio and Luigi Elio Adinolfi

Article Type: Case Report | First Published: March 31, 2018

PDB is a progressive monostotic or polyostotic metabolic disease characterized by a focal abnormal bone remodeling, with an increased bone resorption and an excessive, disorganized new bone formation. It affects both men and woman, with a slight predominance in men....

 Open Access DOI:10.23937/2572-3243.1510043

Survey of Current and Prospective Approaches in Bone Grafting Technology

William Snyder, Brandon Leighton, Stephanie Kidd, Stephen Shively, Jon Gorog and Jonathan W Lowery

Article Type: Review Article | First Published: March 30, 2018

It is estimated that more than 500,000 bone grafting surgeries occur annually in the US to repair or replace defects. Significant progress has been made in this field in recent years, thus making it opportune to survey the technologies currently available and highlight promising future strategies. Here, we offer a timely summarization of the field separated into three areas: Autografts-where bone tissue is harvested from the patient; allografts- taken from cadavers or animals; and intelligently-...

 Open Access DOI:10.23937/2572-3243.1510042

Development of Multi-Family Group and Mindfulness Treatment for Chronic Pain: Preliminary Outcomes

Crystal Lederhos, Tracy L Skaer, Michael Orr, Celestina Barbosa Leiker, Donelle N Howell and Dennis G Dyck

Article Type: Research Article | First Published: October 11, 2017

Chronic Pain (CP) affects over 100 million people in the US and is responsible for $635 billion in direct and indirect costs annually. Behavioral and family education and support can reduce pain intensity and related negative consequences of pain....

 Open Access DOI:10.23937/2572-3243.1510041

The Short-Term Effects of a Single Lecture on Undergraduate Physiotherapy Students' Understanding Regarding Pain Neurophysiology: A Prospective Case Series

Koya Mine, Sam Gilbert, Junko Tsuchiya and Takashi Nakayama

Article Type: RESEARCH ARTICLE | First Published: September 11, 2017

78 third-year students from the Tokyo University of Technology participated in this study. An 80-minute one-off lecture regarding pain neurophysiology was delivered. Understanding of pain neurophysiology was assessed through a Japanese version of Neurophysiology of Pain Questionnaire (NPQ), immediately before, after, and one month after the lecture....

 Open Access DOI:10.23937/2572-3243.1510040

Intramedullary Gas not Related to Infection

Marian Vives Barquiel , Jose Roberto Ballesteros Betancourt, Raquel Garcia Tarrino, Manel LLusa, Guillem Claret, Xavier Tomas Batlle, Borja Garcia Torres, Guillem Navarro, Jose Estrada and Alex Soriano

Article Type: Case Report | First Published: August 31, 2017

The presence of gas in joints or soft tissues is usually indicative of infectious pathology or degenerative diseases. However, the presence of gas inside the medullary canal in the diaphysis of long bones is an uncommon condition, and it is often associated with fractures or previous surgeries....

 Open Access DOI:10.23937/2572-3243.1510039

Iron Determination in Whole Blood Samples of Dystrophic Mouse Strains Using X-Ray Fluorescence Spectrometry

Sabrina Metairon, Cibele B Zamboni, Dalton Nogueira da Silva Giovanni, Miriam F Suzuki, Carlos R Bueno Jr and Marcia de Almeida Rizzutto

Article Type: Research Article | First Published: August 26, 2017

Several diseases can be monitored by assessing the variation of specific ion concentration in body fluids. This study proposes an alternative analysis, based on the X-ray fluorescence spectrometry technique, for the investigation of iron (Fe concentration determination) in whole blood of the dystrophic animal models....

 Open Access DOI:10.23937/2572-3243.1510038

Survey of Pain Therapies in Marfan Syndrome

Traci J Speed, Matthew Hand, Paul D Sponseller, Kayode A Williams and Claudia M Campbell

Article Type: Research Article | First Published: August 05, 2017

Pain in Marfan syndrome is common, although frequently under diagnosed and undertreated. Few studies have investigated the treatment of pain symptoms in Marfan syndrome and no study has reported on the use of opioid therapy in this patient population. This study aims to characterize the use of pain treatment interventions, including opioid use in individuals with Marfan syndrome....

 Open Access DOI:10.23937/2572-3243.1510037

Molecular Changes at the Post-Synapse and Improved Motor Function Suggest Accelerated Recovery with SARM Treatment in an Androgen-Depleted Animal Model of Nerve Injury

John Bryant, James MacKrell, David Gifondorwa, Benjamin Yaden, Bethany Monroe, Kimberly Tyler, Joshua Davis, Alexander Culver, Pamela Shetler, Prabhakar Jadhav, Henry Bryant and Venkatesh Krishnan

Article Type: Research Article | First Published: June 22, 2017

Nerve crush injury at focal sites causes rapid muscle atrophy in the connected muscle downstream of the affected motor end plate, and results in profound functional and metabolic deficits. This report characterizes the resultant functional and molecular changes at the post-synapse in an androgen depleted mouse model of reversible nerve injury....

 Open Access DOI:10.23937/2572-3243.1510036

Floating First Metacarpal: Fracture Dislocation of the Trapezio-Metacarpal Joint Associated with Fracture of the Base of the Proximal Phalanx: A Case Report

Hamdi Kaziz, Thabet Mouelhi, Walid Osman, Nader Naouar and Mohamed Laziz Ben Ayeche

Article Type: Case Report | First Published: June 21, 2017

Floating first metacarpal has been scarcely described in the literature. Fracture dislocation of the trapezio-metacarpal joint has been reported more than the isolated form but deemed exceptional....

 Open Access DOI:10.23937/2572-3243.1510035

Minimally Invasive Percutaneous Screw Fixation of Phalangeal Fractures of the Hand

Simon-Perez C, Garcia-Virto V, Garcia-Medrano B, Rodriguez-Mateos JI, Faour-Martin O and Martin-Ferrero MA

Article Type: Research Article | First Published: June 01, 2017

This study present the results of an effective, minimally invasive treatment method for displaced diaphyseal and articular fractures of hand phalanges, which are difficult to manage and frequently involve complications stemming from excessive treatment....

 Open Access DOI:10.23937/2572-3243.1510034

Acute Lymphoblastic Leukemia in Systemic Lupus Erythematosus Disguise: A Case Report

Gaafar Ragab, Hala El-Gendy and Rasmia M El-Gohary

Article Type: Case Report | First Published: June 08, 2017

The present report describes the case of an 18-year-old male exhibiting Acute Lymphocytic Leukemia (ALL). He initially presented with a multitude of rheumatic manifestations that were attributed to Systemic Lupus Erythematosus (SLE). The initial peripheral smear and bone marrow exam did not show any abnormal cells that developed later on along his disease course....

 Open Access DOI:10.23937/2572-3243.1510033

Entrapment of the Common Peroneal Nerve due to Multiple Hereditary Exostoses with Synostosis of the Proximal Tibiofibular Joint

Ingo Schmidt

Article Type: Short Communication | First Published: May 19, 2017

A 37-year-old male presented with progredient weakness of dorsiflexion in his left ankle since 5 months that was accompanied with sensory deficits in the superficial peroneal nerve area at the dorsal aspect of his left foot. Additionally, the patient reported increasing pain around his left Proximal Tibiofibular Joint (PTFJ). There was a history of known Multiple Hereditary Exostoses (MHE) that was primarily diagnosed with patient's age of 8 year...

 Open Access DOI:10.23937/2572-3243.1510032

Is Bony Evidence of Enthesial Reaction Sufficient for Differential Diagnosis?

Bruce Rothschild

Article Type: Research Article | First Published: May 10, 2017

Enthesial reaction, as a stress or disease marker, has been a generalized perspective, largely untested as to its veracity. Perhaps valid with soft tissue visualization by computerized tomography or magnetic resonance imaging, examination of standard radiographs reveals minimal evidence of enthesial reaction. The current study seeks to assess the disease-specificity of enthesial reaction by examining the primary evidence that of disease-related v...

 Open Access DOI:10.23937/2572-3243.1510031

Treatment of Sports-Related Injured Knee with Incidental Extra-articular Giant Cell Tumor of the Pes Anserinus Tendon Sheath

Sungwook Choi, Younghee Maeng, Kyungryeol Lee and Donghee Kim

Article Type: Case Report | First Published: February 13, 2017

We report a case of a 21-year-old male with knee injury with a giant cell tumor of the tendon sheath resulting in a pes anserinus. As seen in this case, in a sports-related knee injury with an associated giant cell tumor, an initial treatment of the mass was performed first. After the confirmation of non-recurrence after 1 year follow up, the treatment of the sports related injury was followed. In any type of knee injury associated with giant cel...

 Open Access DOI:10.23937/2572-3243.1510030

Serum Sclerostin and Muscle Strength in Alcoholics

Emilio Gonzalez-Reimers, Lucia Romero-Acevedo, Geraldine Quintero-Platt, Candelaria Martin-Gonzalez, Patricia Cabrera-Garcia, M Angeles Gomez-Rodriguez, Elisa Espelosin-Ortega and Francisco Santolaria-Fernandez

Article Type: Research Article | First Published: January 27, 2017

Chronic alcoholic myopathy is a common complication of alcoholism, leading to muscle atrophy and reduced muscle strength. Sclerostin inhibits bone synthesis in situations of reduced load, such as prolonged bed rest or spinal cord injury. The aim pf this study is to analyze the behavior of serum sclerostin in chronic alcoholic myopathy....

 Open Access DOI:10.23937/2572-3243.1510029

Diaphyseal Femur Fractures in Children: A Preliminary Study Comparing the use of Elastic Stable Intramedullary Nailing (ESIN) Versus Locking Compression Plates (LCP)

Carlos Acosta Olivo, J Antonio Ibargüengoytia, Felix Vilchez Cavazos, J Fernando de la Garza Salazar, J Alberto Moreno, Victor Peña Martinez and Eloy Cardenas Estrada

Article Type: Research Article | First Published: January 26, 2017

We conducted a prospective, longitudinal, randomized clinical trial on patients aged 5-16 years with diaphyseal femur fractures. All patients weighed more than 30 kg and exhibited no evidence of distal neurovascular compromise or severe polytrauma. We evaluated radiographic consolidation and knee flexion and extension mobility....

 Open Access DOI:10.23937/2572-3243.1510028

Appropriateness and Suggested Use of MRI in Management of Shoulder Pain

Alan W Reynolds, AB and April D Armstrong, MD, FRCSC

Article Type: Case Report | First Published: January 24, 2017

Magnetic resonance imaging (MRI) accounts for a significant proportion of the cost to manage patients with shoulder pain. Improved decision making for MRI use could result in a meaningful reduction in the total number of studies ordered and thereby costs of treating shoulder pain. This study aimed to document MRI ordering patterns for patients with shoulder pain and to propose a protocol to guide efficient management of these patients....

 Open Access DOI:10.23937/2572-3243.1510027

Necrotizing Fasciitis without Inflammatory Signs in Patients Receiving Anti-Interleukin-6 Receptor Antibody (Tocilizumab): Two Cases Report

Masaki Fujioka, Kiyoko Fukui and Satoko Ishiyama

Article Type: Case Report | First Published: November 01, 2016

Tocilizumab is a monoclonal antibody directed against the interleukin-6 receptor and used for the treatment of rheumatoid arthritis (RA). However, patients treated with tocilizumab have risk of infection, such as necrotizing fasciitis (NF). We report two cases of NF involving patients who had been treated with tocilizumab, and highlight the risk of serious soft tissue infection....

 Open Access DOI:10.23937/2572-3243.1510026

Recovery of Functional Diaphragmatic Activity following Complicated Unilateral or Bilateral Phrenic Nerve Injuries using Multi-Modality Treatment

Matthew R Kaufman, Lisa Schneider, Andrew I Elkwood, Kameron S Rezzadeh and Reza Jarrahy

Article Type: Original Article | First Published: October 24, 2016

Background: Diaphragmatic paralysis may occur as a result of dysfunction in the central nervous system or phrenic nerves leading to inspiratory muscle weakness and a restrictive ventilatory deficit. Phrenic nerve reconstruction and diaphragm pacemakers have each been studied independently as effective therapeutic modalities. Methods: We report three cases of diaphragmatic paralysis in patients with particularly complex pathological processes to i...

 Open Access DOI:10.23937/2572-3243.1510025

Deep Venous Thrombosis in Behcet's Syndrome: Is Anticoagulation Necessary?

Nieves Marie Leonardo and Julian McNeil

Article Type: Case Report | First Published: October 22, 2016

Deep vein thrombosis (DVT) in the lower extremities is a common medical presentation. Anticoagulation is the cornerstone of management. However, not all DVTs require anticoagulation. We report a case of DVT in a patient with Behcet's Syndrome where venous inflammation is the primary pathology and anti-inflammatory therapy is primary and the role of anti-coagulation is moot....

 Open Access DOI:10.23937/2572-3243.1510024

Effects of Seated Whole-Body Vibration Exposure on Cervical and Trunk Proprioception and Static and Dynamic Postural Stability

Takashi Nagai, Heather M Bansbach, Mallory S Faherty, John P Abt, Timothy C Sell and Scott M Lephart

Article Type: Research Article | First Published: October 05, 2016

Prolonged exposure to seated whole-body vibration (WBV) is considered a risk factor for neck pain (NP) and low back pain (LBP) in aircrew. Decreased trunk proprioception following WBV exposure has been previously reported. Proprioceptive feedback from the mechanoreceptors of the neck and trunk regions plays an important role in maintaining proper postural stability; therefore, it was hypothesized that WBV exposure would negatively affect both cer...

 Open Access DOI:10.23937/2572-3243.1510023

Phoenix Project for Improving the Quality of Life in Rheumatic Diseases: Preliminay Results

Middei Sonia, Pasqualucci Simona and Martin-Martin Luis Severino

Article Type: Research Article | First Published: October 03, 2016

Rheumatic chronic diseases (RCD) are among the most common chronic non-communicable diseases. They are the leading cause of disability in developed countries, and consume a large amount of health and social resources. The purpose of this preliminary study (PHOENIX PROJECT) was to evaluate changes in the quality of life of patients suffering from RCD followed by talks in Group Counseling for emotional support. Group Counseling talks for emotional ...

 Open Access DOI:10.23937/2572-3243.1510022

Current Approaches in Myofunctional Orthodontics

Begum Gokce and Burcak Kaya

Article Type: Short Review | First Published: September 30, 2016

Functional matrix theory is the most widely accepted theory of craniofacial growth recently. Moss and Salentijn, have suggested that the craniofacial growth is the result of the changes in functional matrix. Accordingly, neither bone nor cartilage is responsible for the growth of the craniofacial skeleton. The growth of the face, is formed by the growth of the soft tissues as a result of functional requirements. The soft tissues grow; and bone an...

 Open Access DOI:10.23937/2572-3243.1510021

The Effects of an Audible Low Frequency Acoustic Waveform on Osteoarthritis: A Pilot Study

Harvey W Wallmann and William R VanWye

Article Type: Research Article | First Published: September 15, 2016

Osteoarthritis (OA), referred to as degenerative joint disease, affects over 30 million U.S. adults, accounting for billions of dollars spent on joint replacements and lost work. Modifiable risk factors for developing OA include excessive body mass, joint injury, muscle weakness, and occupation as well as non-modifiable factors such as female gender, increasing age, and genetic predisposition....

 Open Access DOI:10.23937/2572-3243.1510020

The Chondral Tissue and PRP. Theory to Support the Use

Marcus Vinicius Danieli

Article Type: Short Review | First Published: September 12, 2016

The hyaline cartilage structure is very complex, with few cells, and without blood and lymphatic vessels or nerves. This makes the healing potential very limited. Knee cartilage injuries are very common, and its treatment is a major challenge. Surgical options available nowadays like chondroplasty, microfractures, mosaicplasty and autologous chondrocyte transplantation still doesn't have satisfactory results, mainly in long term....

 Open Access DOI:10.23937/2572-3243.1510019

A Longitudinal Study of the Prediction of Pathologic Spinal Fractures in Multiple Myeloma with Trabecular Microarchitecture and CT-Based Finite Element Analyses

Miyuki Takasu, Chihiro Tani, Yoko Kaichi, Baba Yasutaka, Chikako Fujioka, Masao Kiguchi, Kumi Oshima, Yoshiaki Kuroda, Akira Sakai, Tatsuo Ichinohe and Kazuo Awai

Article Type: Original Research | First Published: August 16, 2016

A total of 22 vertebral bodies from 14 patients with multiple myeloma were examined by 64-detector row CT prior to follow-up CT that showed new pathologic spinal fractures. Tissue bone mineral density (tBMD), trabecular parameters, and mechanical properties were calculated for three vertebrae, comprising a vertebra that would become fractured and the two adjacent vertebrae. Areas of lytic lesions were also obtained in the axial images containing ...

 Open Access DOI:10.23937/2572-3243.1510018

Mechanical Fatigue Analysis Comparing Two Locking Plates in a Metaphyseal Fracture Model of the Distal Ulna

M Brodbeck, A Spiegel, J Hunt and J Gruenert

Article Type: Research Article | First Published: August 16, 2016

The purpose of the study was to test the mechanical fatigue properties (fatigue limit and fatigue strength) of two locking plates designed for the distal ulna. Distal Ulna Plate 2.5 (Medartis, Basel, Switzerland) and 2.0 mm LCP Distal Ulna Plate (DePuySynthes, West Chester (PA), USA) were used....

 Open Access DOI:10.23937/2572-3243.1510017

Developmental Insights into Osteoarthritis Increase the Applicability of New Animal Models

Brunt LH, Kague E and Hammond CL

Article Type: Review Article | First Published: July 14, 2016

Osteoarthritis (OA) is an increasingly common degenerative joint condition, estimated to affect more than 100 million people worldwide and more than 40% of people over 70 years of age. There is currently no pharmacological cure. The genetic contribution to osteoarthritis is estimated at between 39 and 60% in knee and hip OA respectively and a number of Genome Wide association studies have identified a number of alleles and loci that confer increa...

 Open Access DOI:10.23937/2572-3243.1510016

Improved Walking Capabilities after Eight Weeks of Hal Exoskeleton-Supported Treadmill Therapy in a Patient with Limb-Girdle Muscular Dystrophy Type 2I

Matthias Sczesny-Kaiser, Rebecca Kowalewski, Mirko Aach, Dennis Grasmucke, Thomas A Schildhauer, Matthias Vorgerd and Martin Tegenthoff

Article Type: Video Case Report | First Published: July 02, 2016

Objective: HAL robot suit is a new voluntary driven exoskeleton for the lower limbs. It has already been demonstrated to improve walking functions in spinal cord injury and stroke patients. So far, it is not known if HAL training may be beneficial in patients with limb girdle muscular dystrophy, too....

 Open Access DOI:10.23937/2572-3243.1510015

Perspectives on Improving the Efficacy of PRP Treatment for Tendinopathy

James H-C Wang and Xavier Nirmala

Article Type: Commentary | First Published: June 30, 2016

Platelet-rich plasma (PRP), popularly called PRP, is almost like a "house-hold" name these days because of its wide recognition by physicians and patients due to its prevalent use. The popularity of PRP is due to its efficacy in treating chronic tendon injury (or tendinopathy) in some clinical studies. It is particularly preferred by elite athletes because PRP injections were reported to accelerate healing and enable quicker return to sport activ...

 Open Access DOI:10.23937/2572-3243.1510014

Medial Epicondylitis and Medial Elbow Pain Syndrome: Current Treatment Strategies

Christina Brady and Anil Dutta

Article Type: Review Article | First Published: June 03, 2016

Medial elbow pain is a common complaint in the active population. The most frequent muscular or tendinous condition to cause medial elbow pain is Medial Epicondylitis (ME). The disorder is classically described as Golfer's elbow due its association with elbow pain caused by excessive eccentric force across the common flexor origin encountered during the golf swing. In the working population, the condition is frequently associated with repetitive ...

 Open Access DOI:10.23937/2572-3243.1510013

Regenerative Therapy in Osteoarthritis of the Knee

Jonathan Theo and Edward Pang

Article Type: Literature Review | First Published: May 21, 2016

Osteoarthritis (OA) is the most common joint disorder in the world. It commonly affects the knee and current treatment options are limited, focusing mainly on symptom relief. It is now known that OA is the result of both mechanical and biological events that disrupt anabolic and catabolic processes in the joint. Recently, research in regenerative therapies has been gaining interest because of its potential to restore normal structure and function...

 Open Access DOI:10.23937/2572-3243.1510012

Outcomes of Non-operative Management of Deep Gluteal Syndrome - A Case Series of Six Patients

Ricardo Goncalves Schroder, Rob Roy L Martin, Valerie L Bobb, Anthony Nicholas Khoury, Ian James Palmer and Hal David Martin

Article Type: Case Series | First Published: April 27, 2016

The detailed history, physical examination, imaging, diagnostic testing, and physical therapy of six subjects diagnosed with deep gluteal syndrome were retrospectively analyzed and reviewed. Conservative treatment included neuropsychiatry management, intra-muscular injections through CT guidance, intra-pelvic assessment/therapy, and a home exercise program. The Visual analog scale (VAS), modified Harris Hip Score (mHHS) was utilized to measure ou...

 Open Access DOI:10.23937/2572-3243.1510011

The Effects of Manual Mobilization on the Mobility of the Thoracic Spine in Patients with Ankylosing Spondylitis

Uwe Lange, Martin Sperling, Katrin Richter, Gabriel Dischereit, Ulf Muller-Ladner and Ingo H. Tarner

Article Type: Original Article | First Published: April 26, 2016

Two groups, each consisting of 12 patients, were treated with standard physiotherapy during a regular inpatient stay. After randomization, one group was also treated with manual mobilization of the thoracic spine for an average of 6 sessions, whereas the other group only received conventional physiotherapy. The primary outcome parameter was the mobility of the thoracic spine represented by the Ott's sign. The secondary outcome parameters were pai...

 Open Access DOI:10.23937/2572-3243.1510010

Exploring Cross-Curriculum Content of Undergraduate Musculoskeletal Therapy Courses Regarding Articular Cartilage; Implications of Surveying UK Healthcare Curriculum Providers

Philip Bright and Karen Hambly

Article Type: Original Article | First Published: March 30, 2016

Assessing curriculum across undergraduate healthcare education can be challenging with potential heterogeneity. Focus on a subset of healthcare may indicate variability in curriculum content. Knee articular cartilage and associated injury and repair procedures demand attention; debilitation and development of osteoarthritis severely affect patient quality of life. The level to which musculoskeletal (MSK) therapy education encompasses this area ac...

 Open Access DOI:10.23937/2572-3243.1510009

Radiographic Follow-up of Transforaminal Lumbar Fusion with Silicon Nitride Spacers: A case Report of Two Patients

Jim A Youssef, Sue Lynn Myhre and B. Sonny Bal

Article Type: Original Article | First Published: March 28, 2016

When non operative actions for degenerative spinal disorders fall flat, surgical intervention frequently becomes the popular choice of treatment. Although the class of pathology matters, the surgical operation will generally include an arthrodesis procedure. The gravity of a successful initial fusion surgery is intensified not only by the growing number of arthrodesis procedures, but also by the rising costs for revisal operations. Additionally, ...

 Open Access DOI:10.23937/2572-3243.1510008

Bone Mineral Density Measured by Quantitative Computed Tomography in pre-pubertal/Early Pubertal children with hypovitaminosis D

Ferenc Peter, Agota Muzsnai, Laszlo Blatniczky and Peter Lakatos

Article Type: Original Article | First Published: March 28, 2016

These examinations were performed in pre-pubertal and early pubertal white European children living in one of the inner Buda districts of Budapest. This region of the city is populated by slightly more well-to-do families than the average. The selection was made in two schools. All parents of studied children provided written informed consent, enrollment included more than 90% of children in the chosen classes. To avoid the effects of pubertal ch...

 Open Access DOI:10.23937/2572-3243.1510007

Immune-mediated Mechanisms and Immunotherapy of Duchenne Muscular Dystrophy

Ruojie He and Cheng Zhang

Article Type: Review Article | First Published: March 01, 2016

The immune response is a critical mechanism for dystrophic muscle pathology and muscle wasting in Duchenne Muscular Dystrophy (DMD). The inflammatory processes are supposed to associate with activation of the innate immune response like macrophages infiltration, T cell-mediated immune response, generation of cytokines and chemokines and the aberrant activation of NF-kB signaling pathway, which contribute to severe muscle necrosis and fibrosis....

 Open Access DOI:10.23937/2572-3243.1510006

Use of CD-ROMS for Digital Image Viewing During New Pediatric Orthopaedic Consults - Do We Need a Standardized Viewer for Digital Imaging?

Czoch Wojciech, William Hennrikus, Alexander Kish and Douglas Armstrong

Article Type: Research Article | First Published: February 01, 2016

The purpose of this study is to perform a practice management evaluation of CD-ROM imaging. Thirty-three patients who presented with images on a CD-ROM before and 33 patients after the addition of DICOM software were compared. Data collected included; site of origin of the CD-ROM, time in minutes spent to access the images, number of computers tried until images were viewed, cases of failure to view the images, quality of the images on a Likert 1...

 Open Access DOI:10.23937/2572-3243.1510005

Treatment of Recalcitrant Lateral Epicondylitis with Autologous Conditioning Plasma

Wing Yum Man, Paul Y Lee and Andrew Rogers

Article Type: Research Article | First Published: December 31, 2015

Background: Platelet-rich plasma (PRP) injections are part of a developing therapy believed to promote healing using the patient's own blood components. Certain studies have shown PRP treatment to be effective in the treatment of various tendinopathies such as lateral epicondylitis. Currently there is no standard method for PRP preparation with manufacturers each claiming various benefits for their system. Purpose: Autologous Conditioning serum (...

 Open Access DOI:10.23937/2572-3243.1510004

Infrequently Encountered Multiple Displaced Proximal Phalangeal Fractures of the Hand: A Surgical Case Report

Hamdi Kaziz, Thabet Mouelhi, Mohamed Amine Triki, Yamen Grissa, Nader Naouar and Mohamed Laziz Ben Ayeche

Article Type: Case Report | First Published: November 16, 2015

Proximal phalangeal fractures are frequently seen in hand injuries. However, multiple proximal phalangeal fractures are uncommon and they are the direct result of a high energy force. The prevalence of multiple phalangeal fractures in our hospital is estimated at roughly 3 cases each year but rarely multiple displaced fractures have been reported. The treatment depends on whether they are displaced, comminuted, compound, intraarticular, spiral, o...

 Open Access DOI:10.23937/2572-3243.1510003

Prevalence of Anti-Gastric Parietal Cell Antibodies and Vitamin B12 Deficiency in Rheumatoid Arthritis

Matthew B Carroll and Christopher M Tessier

Article Type: Original Research Article | First Published: October 14, 2015

Recent studies are lacking in assessing presence of both the anti-gastric parietal cell (GPC) antibody and concurrent vitamin B12 deficiency in Rheumatoid Arthritis (RA) patients in the era of more aggressive disease modifying therapy. We recruited patients to one of three arms: those with RA, autoimmune thyroid disease (AITD), and no known autoimmune disorder (controls). A one-time serum assessment of vitamin B12 level, methylmalonic acid, and a...

 Open Access DOI:10.23937/2572-3243.1510002

Management of Occupational Shoulder Injuries in Primary Care

Glenn Brown, Kayne Park and Ryan T Bicknell

Article Type: Review Article | First Published: September 28, 2015

The shoulder is the most mobile joint in the body and is comprised of an intricate complex of muscles, tendons, and ligaments. Due to thismobility and heavy reliance on arms, shoulder injuries are one of the most debilitating and common disorders afflicted in the workplace. They have been categorized as a high impact injury by the workplace safety and insurance board (WSIB) of Ontario due to the long recovery and return to work (RTW) times....

 Open Access DOI:10.23937/2572-3243.1510001

The Effects of Whole-Body Vibration Training for Rehabilitation after ACL Reconstruction: A Systematic Review

Y. Osawa, Y. Oguma, T. Hashimoto and Naokata Ishii

Article Type: Review Article | First Published: September 21, 2015

We investigated the effects of short-term WBVT program for rehabilitation after ACL reconstruction on postural control, knee position sense, and knee laxity. This review was restricted to randomized controlled trials, which investigated the rehabilitation effects of WBVT on physical function compared with conventional rehabilitation program. Data from a total of 99 participants with ACL reconstruction in 3 studies were included. Articles with hig...


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